Digital Commons Network^™

List Of Participants, Jennifer Spohrer

Blended Learning in the Liberal Arts Conference

List of faculty and staff participating in the Blended Learning Conference held at Bryn Mawr College on 7-8 May 2012.

Increased Modulation By Cognitive Control Region During Fmri Working Memory Task Suggest Inefficiencies In Network Connectivity In Children With Adhd, Ashley Burgess

Honors College Theses

Attention Deficit / Hyperactivity Disorder is a neurodevelopmental disorder common among children and adolescent populations whose symptoms are believed to be caused by deficits in executive functioning processes such as working memory. Using fMRI analyses, differences in the modulatory influence exhibited by the dorsal anterior cingulate cortex (dACC) on cortico-striatal regions implicated in working memory (2-back) (Owen et al 2005) was assessed between children with ADHD (twenty-three participants; mean age 6 yrs: 6.4-14.9 yrs) and healthy controls (twenty-six participants; mean age 10.1yrs: 6.3-14.1 yrs). Modulatory influence is defined as the degree to which one region exerts control on another region …

Ber And Folate Deficiency: A Comprehensive Overview Of Dna Base Excision Repair And The Effect Of Dietary Folate, Lydia Lanni

Honors College Theses

Folate is the naturally occurring form of water-soluble B vitamin that is found in foods such as leafy vegetables, fruits, legumes, etc. Dietary supplementation of folate has shown to be protective against neural tube defects and other congenital disorders, and of recent, its role in carcinogenesis has been of special interest. Though mechanistically unclear, a positive correlation has been observed between folate deficiency in the diet and decrease function of DNA base excision repair pathways. DNA base excision repair, commonly referred to as BER, is an important cellular process that is responsible for the removal and repair of individual damaged …

Seeds For Change: Examining The Association Between Race, Food Security, And Urban Agriculture, Komal Razvi

Honors College Theses

Access to healthy, nutritious food is one of the most basic human needs. Unfortunately, a large portion of the global population, including that of the United States, has limited access to such food, hence putting families in a state of food insecurity. Food insecurity occurs when households are unable to (or struggle to) provide adequate food to all household members due to lack of funds or food resources. This phenomenon is considered to be a major concern in many urban settings such as Detroit, as it is a characteristic of societal distress. Interestingly, research has shown that while food insecurity …

Exploratory Study Of Immigrant Kenyan Mothers Knowledge, Beliefs And Attitudes About Health And Nutrition, Akua Smith

Health and Kinesiology Theses

The focus of this study was Sub Saharan African women living in the U.S. and their knowledge, beliefs and attitudes about good health and nutrition and how their knowledge, beliefs and attitudes affect their behaviors and the behaviors of their children. Social Cognitive Theory was selected as the best fit behavioral model and was utilized in this study. The research method used for this study was traditional focus groups, which provide a forum for both researcher and participant to expound on the study subject matter through guided discussion, combined with photo voice, a visual elicitation method. In this study the …

Detection Of Single-Stranded Dna Viruses In Insects And Wild Vegetation, Marco Padilla Rodriguez

USF St. Petersburg campus Honors Program Theses (Undergraduate)

The smallest viruses known to infect eukaryotic organisms contain circular, singlestranded (ssDNA) genomes. Viruses with these characteristics infect economically important animals (Circoviridae) and food crops (Geminiviridae). Circoviruses were traditionally thought to only infect vertebrates; however, recent studies have characterized circoviruses in dragonflies, suggesting that these viruses may be widespread within insect populations. Since there has not been an effort to further characterize circoviruses in these populations, the first objective of this study is to survey various insect species for the presence of circoviruses. A Polymerase Chain Reaction (PCR) assay revealed a novel circovirus genome (~1700 nucleotides) in a Eurycotis floridana …

Faculty And Staff Honored At 2012 Recognition Dinner, University Relations

Campus News Archive

The event provides the campus an opportunity to congratulate 2012 award recipients and thank faculty and staff retirees for their service to the Morris campus.

Population Based Model Of Gonorrhea And Interventions Against Increased Antibiotic Resistance, Courtney Henry

Theses and Dissertations

Gonnorrhea is an infectious sexually transmitted disease (STD) caused by the bacterium Neisseria gonorrhoeae that commonly reproduces in the reproductive tract.The Centers of Disease Control and Prevention (CDC) estimate that more than 700,000 individuals in the U.S. contract new gonorrheal infections per year. During recent years, there has been a progressive global increase of drug-resistant strains of gonorrhea. Therefore, there exists the necessity for health organizations to encourage the monitoring, research and development of innovative treatment regimens. We have developed multiple mathematical models to explore the gonorrheal disease state. The first objective of model formulation was to fit the model …

Characterization Of Superhydrophobic Surfaces Fabricated Using Ac-Electrospinning And Random Particle Deposition, Mohamed Samaha Jr.

Theses and Dissertations

Surfaces with static contact angle greater than 150 degrees are typically classified as superhydrophobic. Such coatings have been inspired by the lotus leaf. As water flows over a superhydrophobic surface, "slip effect" is produced resulting in a reduction in the skin-friction drag exerted on the surface. Slip flow is caused by the entrapment of a layer of air between water and the surface. Superhydrophobicity could be utilized to design surfaces for applications such as energy conservation, noise reduction, laminar-to-turbulent-transition delay, and mixing enhancement. A popular method of manufacturing a superhydrophobic surface is microfabrication in which well-designed microgrooves and/or poles are …

Assessment Of The Utilization Of Hiv Interventions By Sex Workers In Selected Brothels In Bangladesh: An Exploratory Study, Nafisa Lira Huq, Mahbub Elahi Chowdhury

The Qualitative Report

In this qualitative study of brothel-based Female Sex Workers (FSWs), the authors explored factors that influence safe sex practices of FSWs within an integrated HIV intervention. Qualitative methods, including focus group discussions (FGDs), in-depth interviews and key informant interviews were applied in four brothels in Bangladesh. Young and elderly FSWs, Sordarnis (Madams who own young FSWs and who may be either active or inactive sex workers themselves), program managers and providers were the participants for this study. Findings showed that condom use was high but not consistent among bonded FSWs (those who are under the control of a Sordarni) who …

N-Terminal Processing Of Ribosomal Protein L27 In Staphylococcus Aureus, J. Harry Caufield

Theses and Dissertations

The bacterial ribosome is essential to cell growth yet little is known about how its proteins attain their mature structures. Recent studies indicate that certain Staphlyococcus aureus bacteriophage protein sequences contain specific sites that may be cleaved by a non-bacteriophage enzyme (Poliakov et al. 2008). The phage cleavage site was found to bear sequence similarity to the N-terminus of S. aureus ribosomal protein L27. Previous studies in E. coli (Wower et al.1998; Maguire et al. 2005) found that L27 is situated adjacent to the ribosomal peptidyl transferase site, where it likely aids in new peptide formation. The predicted S. aureus …

Mechanism Of Inhibition Of Influenza A Virus M2 Proton Channel, Douglas Randall Bretzing, Victoria Man-Fung Burr

Faculty Publications

The influenza A virus integral membrane protein, M2, is a proton-conducting channel. The ability of influenza A virus to unpack its genome, replicate, and infect its host is contingent upon the M2-mediated acidification of the viral interior. The antiviral drugs amantadine and rimantadine were previously effective in blocking proton influx through M2; however, mutations in the proton channel have rendered these drugs ineffective. Multiple models for the inhibiting mechanism of the adamantane drugs have been hypothesized. In an attempt to better understand the mechanism of M2 inhibition, and ultimately to assist in the development of a replacement M2-targeting antiviral drug, …

Behaviors That Eliminate Health Disparities For Racial And Ethnic Minorities: A Narrative Systematic Review, Truman Ryan Keys

Proceedings of the New York State Communication Association

Within the health care provider-health care recipient relationship the communication must be culturally competent to eliminate barriers to equitable health care for all Americans. This assertion has conceptual grounding in Public Law 106-129 (the Health Care Research and Quality Act of 1999) and Public Law 106-525 (the Minority Health and Health Disparities Research and Education Act of 2000). This narrative systematic review examines this assertion by using selection and exclusion criteria to gather interventions, assessments, and testimonies conducted from 2000-2007. Reports that were not eliminated via these criteria were analyzed to determine the effect of specific practices that were undertaken …

Evolution And Biogeography Of Fire-Eye Antbirds (Genus Pyriglena): Insights From Molecules And Songs, Marcos Maldonado Coelho

Dissertations

The importance of climatic and geologic factors as drivers of population differentiation and speciation in the Neotropical region has long been appreciated. However, many questions remain regarding their roles underlying the processes and patterns of diversification. Studies conducted in distinct regions containing a suite of geological and ecological conditions constitute ideal scenarios to assess the role of Pleistocene climatic changes, rivers, and mountain building as historical diversification mechanisms. In chapters 1 and 2, I used an integrative approach combining molecular phylogenetics, phylogeography and population genetics to elucidate the importance of climatic and geological factors as engines of diversification. I focused …

2012 May 5-6

Commencement Programs

No abstract provided.

Medical School Watercooler Newsletter - May 6, 2012, Lindsey Lyle

Watercooler Newsletter

This is the May 6, 2012 edition of the Frederick P. Whiddon College of Medicine's newsletter - Watercooler.

Contents Include:

• Seniors Prepare for Graduation, Residency Assignments
• Books Collected During National Library Week Delivered to USA Children's Medical Center
• Dr. Brevard Receives Distinguished Alumnus Award from St. Paul's Episcopal School
• Medical Student Kickball Team Wins Championship Game
• USA Center for Autism and Developmental Disabilities To Host Autism Grand Rounds

Commencement Convocation Program, St. Petersburg, May 6, 2012, University Of South Florida St. Petersburg

USF St. Petersburg Graduations and Commencements

King O'Neal Award - John Boda, Andrew Thurston, Emily Young; Outstanding Graduate - Britanny Lyp

Education Preparation To Respond To The Needs Of Homeless Children & Youth: Perceptions Of School Personnel, Sarah Elizabeth Harris

Honors Scholar Theses

Each year, 1.5 million children spend at least one night in a homeless situation (Public Broadcast Station, 2009). These students struggle to achieve academically with schooling that is inconsistent in both location and curriculum and living conditions that are not conducive to homework and study. This study examined educators’ perceptions of homelessness and the academic and social needs of homeless students, as well as the preparation that teachers and other school personnel report that they have received in pre-service preparation programs and through professional development opportunities to address the unique needs of homeless children and youth. The project explored educator …

Effect Of Plant-Derived Molecules On Acinetobacter Baumannii Biofilm On Abiotic Surfaces, Ryan P. Pelletier

Honors Scholar Theses

The emergence of multiple drug resistant (MDR) Acinetobacter baumannii has lead to an increased interest in finding alternative antimicrobial compounds for controlling the pathogen. The present study investigated the effect of three plant-derived antimicrobials, namely eugenol (EUG), carvacrol (CAR), and thymol (THY), on A. baumannii biofilms. Using concentrations equal to or greater than the minimum bactericidal concentration (MBC) of each compound, the ability of EUG, CAR, and THY to inactivate the mature biofilms of three strains of MDR A. baumannii on polystyrene microtiter plates and stainless steel coupons was examined. All three plant-derived compounds significantly inactivated the bioflims of all …

Elucidating The Mechanism Of Antimigratory Activity Of Cardiac Glycosides, Joshua H. Johnson

Honors Scholar Theses

The focus of this research is on cell migration and how it can be better understood through the use of small molecules that modulate cell migratory activity. The results have particular relevance in the realm of cancer pharmacology. Cardiac glycosides, which are known inhibitors of the eukaryotic Na⁺/K⁺-ATPase, have been determined to have antimigratory activities through the screening of several small molecule libraries. Here we investigate the antimigratory activities of the cardiac glycoside digitoxin as well as its analogs that we synthesized. Antimigratory activity was determined by conducting a wound closure assay with MDA-MB-231 human breast …

Point Of Use Water Treatment With Forward Osmosis For Emergency And Population Migration Relief, Ethan L. Butler

Honors Scholar Theses

According to the World Health Organization, 780 million people do not have access to an improved water source. Many of these people are victims of emergencies and/or forced population migration, and suffer from malnutrition and diarrheal illness as well. One promising solution is Hydration Technology Innovation’s (HTI’s) forward osmosis (FO) systems: the HydroWell and Village System. These systems produce clean drink from almost any source water. A systematic evaluation of HTI’s systems was performed. Bench-top testing showed that HTI’s membrane can remove significant concentrations of inorganic contaminants that have been found to be problematic in disaster-prone regions. A cost model …

University Of Alaska Anchorage Commencement Program May 2012, N/A N/A

Commencement

These official programs are distributed to attendees of the annual commencement ceremonies. The programs include the event schedule as well as the degrees and honors awarded, listing recipients of the degrees and honors. May 2012

Dmft And Its Possible Determinants In The Honduran Population, Patrick T. Cooper

Honors Scholar Theses

Objectives: This study was designed to investigate the dental health status of several communities in Honduras in terms of the DMFT index (decayed missing and filled teeth). Specifically the study focused on comparisons of the Garifuna (a maroon community in Tela) with the people of San Jose, Copan, and others who traveled from other regions to come to a medical clinic. These results were also compared to other populations of developing and developed countries. Through looking at each participant’s DMFT score, many possible correlations to oral health were explored including region, age, gender, snacking, tobacco use, and oral hygiene. …

Improved Tissue Caliper, Kenneth Ted-Luck Hung

Honors Scholar Theses

My honors thesis will be covering the work that I am doing for my senior design project. My senior design project involves building a tissue caliper for medical device company, Covidien. During medical research and development it is often necessary to measure and document the thickness of tissue samples and media (simulated tissue foam). A device known as a tissue caliper is currently used to perform such measurements. Our project requires us to design, build, calibrate, and validate an instrument, which will be capable of measuring sample thicknesses ranging from 0.10 to 1.00 inches with an accuracy of ± 0.005 …

Young Black Children's Representations Of The Father Figure In Low-Income Households, Shawnae Shalae Thompson

Honors Scholar Theses

This study investigated the cognitive-emotional schemas surrounding the father role in 50 young, low-income, Black children in relation to the amount of father involvement in the first 5 years of their lives. These representations were framed within four parenting categories: Nice, Mean, Authoritative, and Authoritarian. Diana Baumrind’s parenting style framework was utilized to create the Authoritative and Authoritarian parenting categories. This question was investigated in low-income families; the impact of gender of the child was also considered. Information on fathers’ involvements in the children’s lives were gathered through interviews and self-reports from the children’s fathers and mothers. Story Stem Narrative …

Ketamine Can Disrupt Episodic Memory (Hours To Days) Consolidation: Effects Of Varying Dose And Retention Intervals, Ryan Darius Tabtabai

Honors Scholar Theses

Memory consolidation is the process wherein short-term, episodic memories are converted into stable, long-term representations. Forebrain N-methy-d-aspartate receptors (NMDARs), particularly frontal cortical and hippocampal receptors, are thought to play a key role in neuronal plasticity and memory consolidation. Ketamine is an NMDA antagonist that disrupts memory, particularly encoding and retrieval processes. Previously we have observed no effect of post-acquisition ketamine treatment (50-100 mg/kg) on memory consolidation in rats performing a delayed-match-to place radial water maze task. The current study reexamined the effects of ketamine (25-100 mg/kg) on memory consolidation in this task over varying retention intervals (4, 24, and 48 …

Salinity Preference Of Alaskan Threespine Stickleback: Test For Divergence In Halotaxis Between Ancestral And Landlocked Populations, David C. Fryxell

Honors Scholar Theses

Glacial retreat during the Pleistocene caused landlocking of anadromous Alaskan threespine stickleback, Gasterosteus aculeatus, furnishing a natural 'experiment' in osmoregulatory divergence. The objective of this study was to assess the effects of individual acclimation and population divergence on salinity preference. Full-sibling families of marine, anadromous, and freshwater-landlocked populations of stickleback were reared in common environments until 3 weeks post-hatch, then were split and acclimated to low or high salinity. At 6 to 8 weeks of age the six experimental groups were tested for salinity preference in a tank that offers fish a choice of compartments with different salinities arranged in …

Improvements To The Forensic Analysis Of Mitochondrial Dna Typing, Elizabeth Montano

Honors Scholar Theses

Sequence analysis of human mitochondrial DNA (mtDNA) is an effective and reliable tool for the genetic characterization of forensic samples. The nature of the mitochondrial genome (mtgenome), its high copy number and small size (~17kb) makes it more resistant to degradation and more stable than nuclear DNA. For this reason mitochondrial DNA is often the only feasible option for the forensic analysis of environmentally compromised samples. Currently the forensic analysis of the mtgenome is restricted to the hypervariable regions, also known as the Displacement loop (d-loop). Previous studies, confirmed in the Strausbaugh lab, have demonstrated an increased variability in the …

Dcm Methylation Is Detrimental To Plasmid Transformation In Clostridium Thermocellum, Adam M. Guss, Daniel G. Olson, Nicky C. Caiazza, Lee R. Lynd

Dartmouth Scholarship

Background: Industrial production of biofuels and other products by cellulolytic microorganisms is of interest but hindered by the nascent state of genetic tools. Although a genetic system for Clostridium thermocellum DSM1313 has recently been developed, available methods achieve relatively low efficiency and similar plasmids can transform C. thermocellum at dramatically different efficiencies. Results: We report an increase in transformation efficiency of C. thermocellum for a variety of plasmids by using DNA that has been methylated by Escherichia coli Dam but not Dcm methylases. When isolated from a dam + dcm + E. coli strain, pAMG206 transforms C. thermocellum 100-fold better …

Metallothionein Gene Dose And The Immune Response, Meaghan Roy-O-Reilly

Honors Scholar Theses

Metallothionein (MT) is a small, cysteine-rich protein with significant immunomodulatory activity. It has been shown to play a critical role in important cellular mechanisms including heavy metal detoxification, essential metal management and the inflammatory response. MT production can be induced by a number of cellular stressors and acts to lessen the harmful effects of oxidizing agents and heavy metal exposure. Previous studies have shown that the dose of the metallothionein gene present in an individual may have significant effects on the adaptive immune response, yet the mechanism behind this phenomenon remains unknown. We hypothesize that the gene dose of metallothionein …