Digital Commons Network^™

Winter Site Fidelity In Secretive Marsh Sparrows Along The Coast Of South Carolina, Susan M. Shaw

Electronic Theses and Dissertations

Salt marshes, which are threatened by sea level rise and development, provide habitat for a distinctive suite of specialized vertebrates, and knowledge of the life histories of salt marsh specialists may help preserve salt marsh fauna in the face of change. I studied wintering site fidelity of Seaside (Ammodramus maritimus), Saltmarsh (A. caudacutus) and Nelson's (A. nelsoni) Sparrows by mist-netting and banding birds at six sites in two salt marshes in South Carolina. I banded 261 sparrows over two winters, 2009-2010 and 2010-2011, and recaptured 92. Across-year return rates were high, but significantly different across species: 43% for Seaside, 63% …

Trail Blazer - Volume 115, Number 12, Morehead State University. Trail Blazer.

Morehead State Trail Blazer Archive

Morehead State Trail Blazer published on December 6, 2012.

A Hunter Virus That Targets Both Infected Cells And Hiv Free Virions: Implications For Therapy, Cody Greer, Gisela García-Ramos

Biology Faculty Publications

The design of 'hunter' viruses aimed at destroying human immunodeficiency virus (HIV) infected cells is an active area of research that has produced promising results in vitro. Hunters are designed to target exposed viral envelope proteins in the membranes of infected cells, but there is evidence that the hunter may also target envelope proteins of free HIV, inducing virus-virus fusion. In order to predict the effects of this fusion on therapy outcomes and determine whether fusion ability is advantageous for hunter virus design, we have constructed a model to account for the possibility of hunter-HIV fusion. The study was based …

Vista: December 6, 2012, University Of San Diego

USD Vista (1965-)

No abstract provided.

Summer Watering Patterns Of Mule Deer And Differential Use Of Water By Bighorn Sheep, Elk, Mule Deer, And Pronghorn In Utah, Andrew V. Shields

Theses and Dissertations

Changes in the abundance and distribution of free (drinking) water can influence wildlife in arid regions. In the western USA, free water is considered by wildlife managers to be important for bighorn sheep (Ovis canadensis), elk (Cervus elaphus), mule deer (Odocoileus hemionus), and pronghorn (Antilocapra americana). Nonetheless, we lack information on the influence of habitat and landscape features surrounding water sources, including wildlife water developments, and how these features may influence use of water by sexes differently. Consequently, a better understanding of differential use of water by the sexes could influence the conservation and management of those ungulates and water …

Daily Eastern News: December 06, 2012, Eastern Illinois University

December

No abstract provided.

Kenyon Collegian - December 6, 2012

The Kenyon Collegian

No abstract provided.

The P2y(12) Antagonists, 2mesamp And Cangrelor, Inhibit Platelet Activation Through P2y(12)/G(I)-Dependent Mechanism, Binggang Xiang, Guoying Zhang, Hongmei Ren, Manjula Sunkara, Andrew J. Morris, T. Kent Gartner, Susan S. Smyth, Zhenyu Li

Saha Cardiovascular Research Center Faculty Publications

BACKGROUND: ADP is an important physiological agonist that induces integrin activation and platelet aggregation through its receptors P2Y(1) (Gα(q)-coupled) and P2Y(12) (Gα(i)-coupled). P2Y(12) plays a critical role in platelet activation and thrombosis. Adenosine-based P2Y(12) antagonists, 2-methylthioadenosine 5'-monophosphate triethylammonium salt hydrate (2MeSAMP) and Cangrelor (AR-C69931MX) have been widely used to demonstrate the role of P2Y(12) in platelet function. Cangrelor is being evaluated in clinical trials of thrombotic diseases. However, a recent study reported that both 2MeSAMP and Cangrelor raise intra-platelet cAMP levels and inhibit platelet aggregation through a P2Y(12)-independent mechanism.

METHODOLOGY/PRINCIPAL FINDINGS: The present work, using P2Y(12) deficient mice, sought to …

The Adverse Effects Periodontal Disease Has On Women, Jennifer Long

Honors Theses

The Adverse Effects Periodontal Diseases Has on Women Periodontal diseases are challenging to define given the number and variety of different oral diseases. This review sought to answer the question: How does a periodontal disease impact a woman throughout the life span? Specifically, this document discussed how, because of the cycling hormones and the effects those hormones have on the different bacteria, women's periodontal diseases differ from men's. Diseases of the mouth were first discovered during the Egyptian period and the information and knowledge about the different diseases advanced as time progressed. From here, non-surgical and surgical treatments were discussed …

Reactive Oxygen Species Production And Brugia Pahangi Survivorship In Aedes Polynesiensis With Artificial Wolbachia Infection Types, Elizabeth S. Andrews, Philip R. Crain, Yuqing Fu, Daniel K. Howe, Stephen L. Dobson

Entomology Faculty Publications

Heterologous transinfection with the endosymbiotic bacterium Wolbachia has been shown previously to induce pathogen interference phenotypes in mosquito hosts. Here we examine an artificially infected strain of Aedes polynesiensis, the primary vector of Wuchereria bancrofti, which is the causative agent of Lymphatic filariasis (LF) throughout much of the South Pacific. Embryonic microinjection was used to transfer the wAlbB infection from Aedes albopictus into an aposymbiotic strain of Ae. polynesiensis. The resulting strain (designated "MTB") experiences a stable artificial infection with high maternal inheritance. Reciprocal crosses of MTB with naturally infected wild-type Ae. polynesiensis demonstrate strong bidirectional incompatibility. Levels of reactive …

Habitat Selection Of Greater Sage-Grouse Centrocercus Urophasianus And Northern River Otters Lontra Canadensis In Utah, Matthew D. Westover

Theses and Dissertations

Greater sage-grouse populations have decreased steadily since European settlement in western North America. Reduced availability of brood-rearing habitat has been identified as a limiting factor for many populations. We used radio-telemetry to acquire locations of sage-grouse broods from 1998 to 2012 in Strawberry Valley, Utah. Using these locations and remotely-sensed imagery, we proceeded to 1) determine which features of brood-rearing habitat could be identified using widely available, fine-scale imagery 2) assess the scale at which sage-grouse selected brood-rearing habitat in our study area, and 3) create a predictive habitat model that could be applied across our large study area to …

Centers Of Cultural Gravity: Cultural Translation In Nublares, William Foster Carr

Theses and Dissertations

In the novel Nublares, Antonio Pérez Henares presents a caveman who typifies the modern, fragmented subject. The protagonist, Ojo Largo, a hybrid child of various cultures, crosses the boundaries between those cultures and negotiates the in-between space as a cultural translator. The concept of the fragmented, hybrid self reflects modern cognitive science. Daniel Dennett's Multiple Drafts model of consciousness presents a fragmented self characterized by "disaggregated agency," a subject consisting of the center of gravity between disparate mental processes and accumulated "narratives." Taking this model as point of departure, this thesis finds a consensus between three novels of prehistory, …

Information Literacy On The Web: How College Students Use Visual And Textual Cues To Assess Credibility On Health Websites, Katrina L. Pariera

Communications in Information Literacy

One of the most important literacy skills in today's information society is the ability to determine the credibility of online information. Users sort through a staggering number of websites while discerning which will provide satisfactory information. In this study, 70 college students assessed the credibility of health websites with a low and high design quality, in either low or high credibility groups. The study's purpose was to understand if students relied more on textual or visual cues in determining credibility, and to understand if this affected their recall of those cues later. The results indicate that when viewing a high …

Binding Of An Indenoisoquinoline To The Topoisomerase-Dna Complex Induces Reduction Of Linker Mobility And Strengthening Of Protein-Dna Interaction., Giordano Mancini, Ilda D'Annessa, Andrea Coletta, Giovanni Chillemi, Yves Pommier, Mark S. Cushman, Alessandro Desideri

Borch Department of Medicinal Chemistry and Molecular Pharmacology Faculty Publications

Long-duration comparative molecular dynamics simulations of the DNA-topoisomerase binary and DNA-topoisomerase-indenoisoquinoline ternary complexes have been carried out. The analyses demonstrated the role of the drug in conformationally stabilizing the protein-DNA interaction. In detail, the protein lips, clamping the DNA substrate, interact more tightly in the ternary complex than in the binary one. The drug also reduces the conformational space sampled by the protein linker domain through an increased interaction with the helix bundle proximal to the active site. A similar alteration of linker domain dynamics has been observed in a precedent work for topotecan but the molecular mechanisms were different …

Diverse Lifestyles And Strategies Of Plant Pathogenesis Encoded In The Genomes Of Eighteen Dothideomycetes Fungi., Robin A. Ohm, Nicolas Feau, Bernard Henrissat, Conrad L. Schoch, Benjamin A. Horwitz, Kerry W. Barry, Bradford J. Condon, Alex C. Copeland, Braham Dhillon, Fabian Glaser, Cedar N. Hesse, Idit Kosti, Kurt Labutti, Erika A. Lindquist, Susan Lucas, Asaf A. Salamov, Rosie E. Bradshaw, Lynda Ciuffetti, Richard C. Hamelin, Gert H.J. Kema, Christopher Lawrence, James A. Scott, Joseph W. Spatafora, B Gillian Turgeon, Pierre J.G.M. De Wit, Shaobin Zhong, Stephen B. Goodwin, Igor V. Grigoriev

Department of Botany and Plant Pathology Faculty Publications

The class Dothideomycetes is one of the largest groups of fungi with a high level of ecological diversity including many plant pathogens infecting a broad range of hosts. Here, we compare genome features of 18 members of this class, including 6 necrotrophs, 9 (hemi)biotrophs and 3 saprotrophs, to analyze genome structure, evolution, and the diverse strategies of pathogenesis. The Dothideomycetes most likely evolved from a common ancestor more than 280 million years ago. The 18 genome sequences differ dramatically in size due to variation in repetitive content, but show much less variation in number of (core) genes. Gene order appears …

Modernization, Sexual Risk-Taking, And Gynecological Morbidity Among Bolivian Forager-Horticulturalists, Jonathan Stieglitz, Aaron D. Blackwell, Raúl Quispe Gutierrez, Edhitt Cortez Linares, Michael Gurven, Hillard Kaplan

ESI Publications

Sexual risk-taking and reproductive morbidity are common among rapidly modernizing populations with little material wealth, limited schooling, minimal access to modern contraception and healthcare, and gendered inequalities in resource access that limit female autonomy in cohabiting relationships. Few studies have examined how modernization influences sexual risk-taking and reproductive health early in demographic transition. Tsimane are a natural fertility population of Bolivian forager-farmers; they are not urbanized, reside in small-scale villages, and lack public health infrastructure. We test whether modernization is associated with greater sexual risk-taking, report prevalence of gynecological morbidity (GM), and test whether modernization, sexual risk-taking and parity are …

Dissolved Organic Matter Composition And Bioavailability Reflect Ecosystem Productivity In The Western Arctic Ocean, Yuan Shen, Cedric Fichot, Ronald Benner

Faculty Publications

Dissolved organic carbon (DOC) and total dissolved amino acids (TDAA) were measured in high (Chukchi Sea) and low (Beaufort Sea) productivity regions of the western Arctic Ocean to investigate the composition and bioavailability of dissolved organic matter (DOM). Concentrations and DOC-normalized yields of TDAA in Chukchi surface waters were relatively high, indicating an accumulation of bioavailable DOM. High concentrations and yields of TDAA were also observed in the upper halocline of slope and basin waters, indicating off-shelf transport of bioavailable DOM from the Chukchi Sea. In contrast, concentrations and yields of TDAA in Beaufort surface waters were relatively low, indicting …

Selection Of Trna Charging Quality Control Mechanisms That Increase Mistranslation Of The Genetic Code, Srujana S. Yadavalli, Michael Ibba

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Mistranslation can follow two events during protein synthesis: production of non-cognate amino acid:transfer RNA (tRNA) pairs by aminoacyl-tRNA synthetases (aaRSs) and inaccurate selection of aminoacyl-tRNAs by the ribosome. Many aaRSs actively edit non-cognate amino acids, but editing mechanisms are not evolutionarily conserved, and their physiological significance remains unclear. To address the connection between aaRSs and mistranslation, the evolutionary divergence of tyrosine editing by phenylalanyl-tRNA synthetase (PheRS) was used as a model. Certain PheRSs are naturally error prone, most notably a Mycoplasma example that displayed a low level of specificity consistent with elevated mistranslation of the proteome. Mycoplasma PheRS was found …

Microfluidic Devices With Integrated Sample Preparation For Improved Analysis Of Protein Biomarkers, Pamela Nsang Nge

Theses and Dissertations

Biomarkers present a non-invasive means of detecting cancer because they can be obtained from body fluids. They can also be used for prognosis and assessing response to treatment. To limit interferences it is essential to pretreat biological samples before analysis. Sample preparation methods include extraction of analyte from an unsuitable matrix, purification, concentration or dilution and labeling. The many advantages offered by microfluidics include portability, speed, automation and integration. Because of the difficulties encountered in integrating this step in microfluidic devices most sample preparation methods are often carried out off-chip. In the fabrication of micro-total analysis systems it is important …

Microflora Of Traditional Mexican Corn Masa And Its Effect On Folic Acid Degradation, Stephen J. Adolphson

Theses and Dissertations

Many Mexican women consume inadequate amounts of folic acid. Fortification of the corn tortilla could be an effective way to help increase the folic acid levels among the Mexican population. Previous studies have shown significant folic acid losses in fortified tortilla dough (masa) as it is held before baking. This loss in folic acid could be due to degradation by lactic acid bacteria naturally present in the masa. The microflora of traditionally made nixtamalized corn masa from six tortilla mills in Guadalajara, Mexico were isolated and characterized, and their effect on folic acid content was evaluated. Isolated bacteria were identified …

Predictors Of Student's Attitudes Toward Science Literacy, Irina I. Holden

Communications in Information Literacy

Being information and science literate are crucial in an age when scientific developments influence the political arena and vice versa. In order to become active and responsible citizens, students must understand such issues as global warming and stem cell research. Furthermore, they must be lifelong learners, capable of researching and educating themselves about new scientific developments. These are some of the complex issues that information literacy educators must address. This article reports on the results of a survey of student's attitudes towards science literacy and lifelong learning, and on variables associated with their attitudes. Most of the students' attitudes were …

A Tangle Net Study On Relative Abundance And Habitat Preference Of Elasmobranchs In North Inlet Estuary, South Carolina, Moriah Heather Moore

Electronic Theses and Dissertations

Although habitat selection is relatively well studied in some elasmobranchs, no field or lab studies have focused on sediment preference, which is important to other benthic marine vertebrates. To determine the relative abundance and sediment preference of shallow water benthic elasmobranch inhabitants of North Inlet, SC, we employed 187 30 minute tangle net sets over two sediment types (mud and sand). The majority of our capture consisted of 41 Dasyatis sayi (tagged 37) and 31 Sphyrna tiburo (tagged 14). Although D. sayi had been recorded in North Inlet, previous studies found greater numbers of congeners D. americana and D. sabina. …

The Effects Of Climate Change And Overexploitation On Birds And Mammals: Phenological Shifts, Range Shifts, And Population Changes, Rachel Denny

Honors Theses

Our world is changing more than many individuals could imagine. Climate change is not a hoax. Comprehensive empirical records of changes since 1900 in local, regional, and global temperature clearly indicate that Earth is warming more rapidly than ever in recorded history. In response, some bird species are already shifting, both phenologically (timing) and geographically. However, the majority of birds are not shifting or not shifting fast enough, and this is resulting in population declines. A much smaller number of studies suggest that mammals are also shifting phenologically and geographically.

If we do not alter our current behaviors soon, Earth …

A Lack Of Willpower May Influence A Leader’S Ability To Act Morally, Tom Karp

The Journal of Values-Based Leadership

Acts of moral leadership do not come without risks of loss of employment, a lessening of personal stature, and compromised mental and physical wellbeing. Thus, the quest to act as a values-based leader necessarily commands the exercise of unfettered willpower and a tenacious willingness to assume such risks.

Why Chinese Neo-Confucian Women Made A Fetish Of Small Feet, Aubrey L. Mcmahan

Grand Valley Journal of History

Abstract for “Why Chinese Neo-Confucian Women Made a Fetish of Small Feet”

This paper explores the source of the traditional practice of Chinese footbinding which first gained popularity at the end of the Tang dynasty and continued to flourish until the last half of the twentieth century.[1] Derived initially from court concubines whose feet were formed to represent an attractive “deer lady” from an Indian tale, footbinding became a wide-spread symbol among the Chinese of obedience, pecuniary reputability, and Confucianism, among other things.[2]^,[3] Drawing on the analyses of such scholars as Beverly Jackson, Valerie Steele …

Bioone Goals & Bioone: Exploring A Collaborative Publishing Model, Heather Joseph

Proceedings of the IATUL Conferences

No abstract provided.

Success Through Working Together: The U.S. National Agricultural Library's Approach To Cooperative Activities, Eleanor G. Frierson, Peggy J. Blake

Proceedings of the IATUL Conferences

No abstract provided.

Interdisciplinarity Across Subject Paths & Institutions: Leading To New Outcomes - The Cal-It2 Project In Detail, Julia Gelfland

Proceedings of the IATUL Conferences

No abstract provided.

"Open Horizon" For Transforming Scholarly Communication In Engineering, Kenneth Frazier

Proceedings of the IATUL Conferences

No abstract provided.

New Collaborations In A Brave World: Building An Agile Consortium For The 21st Century, Adrian W. Alexander

Proceedings of the IATUL Conferences

No abstract provided.