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Functional Interactions Between Par-1b Protein Kinase And Rnf41 E3 Ubiquitin Ligase, Katherine Terese Vega

All Theses and Dissertations (ETDs)

The Par-1 family of serine/threonine protein kinases functions to regulate cell polarity and is conserved from yeast to humans. Par-1 is encoded by one of six Par: partitioning-defective) genes: Par-1-6) originally identified in a genetic screen conducted in Caenorhabditis elegans: C. elegans). The mammalian Par-1 family is comprised of four members: Par-1a, b, c and d). Par-1 kinases are regulated by two arms of the Protein Kinase C: PKC) pathway. Atypical Protein Kinase C: aPKC) phosphorylates Par-1b on a conserved threonine residue: T595) and I participated in studies demonstrating that novel Protein Kinase C: nPKC) activates Protein Kinase D: PKD) …

Effect Of Strategic Thinking In Human Resource Management Strategies “Analytical Field Study Of The Views Of A Sample Of Managers In The Iraqi Ministry Of Health”, Salah Al-Din Al-Kubaisy

Journal of Economics and Administrative Sciences

The researcher attemptstodiagnosethe level of theeffect of strategic thinkingskills (intuition,meditation,creativity)of themanagers in the Ministry ofHealth in Iraqand some ofits institutionsin the formulation ofhuman resources management: (selection, training, incentivence , performance appraisal (Recognizing the importance of the subjects studied, and because of the importance of the expected results of the field under consideration, researcher selected a sample of Size (50) general managers and department managers in the office of the Ministry and the Departments of health Baghdad –Karkh, Rusafa, Medical City and Peoples Clinics, as most interested in the subject the most significant result obtained indiadcated that level of skills of …

Nature, Culture, And Social Engineering: Reflections On Evolution And Equality, Linda C. Mcclain

Faculty Scholarship

This book chapter explores evolution and morality by considering the appeal to nature, and in particular to how evolution has shaped female and male brains differently, to explain evident sex differences and the persistence of sex inequality. It uses as illustrative the popularizing accounts of male and female brains found in Louann Brizendine, The Female Brain and The Male Brain, and the portrayal in such accounts of fundamental male and female differences in human mate selection and parenting. Drawing on the work of scientist and philosophers, the chapter critiques these accounts for engaging in an increasingly popular “neurosexism.” Such neurosexism …

Weakest-Link Attacker-Defender Games With Multiple Attack Technologies, Daniel G. Arce, Dan Kovenock, Brian Roberson

Economics Faculty Articles and Research

In this article, we examine a model of terrorism that focuses on the tradeoffs facing a terrorist organization that has two qualitatively different attack modes at its disposal. The terrorist organization's objective is to successfully attack at least one target. Success for the target government is defined as defending all targets from any and all attacks. In this context, we examine how terrorist entities strategically utilize an efficient but discrete attack technology e.g., suicide attacks when a more conventional mode of attack is available, and the optimal anti-terrorism measures.

The Journal At Fifty, Archie P. Mcdonald

East Texas Historical Journal

No abstract provided.

Land Snails In Ephemeral Pools At Ottine Swamp, Gonzales County, Texas, Frank J. Dirrigl, Robert H. Mohlenbrock

School of Integrative Biological & Chemical Sciences (Formerly Dept. of Biology)

We found five species of terrestrial land snails in dried ephemeral pools at Ottine Swamp, Palmetto State Park, Gonzales County, Texas. We recorded four species previously known (Anguispira stronglyodes, Mesomphix friabilis, Olygyra orbiculata, and Rabdotus dealbatus) and added a new occurrence (Mesodon thyroidus) to the list of species in the park.

Se encontraron cinco especies de caracoles terrestres en los fondos secos de unos charcos efímeros en Ottine Swamp, Palmetto State Park, en el condado de Gonzales, Texas. Registramos cuatro especies conocidas anteriormente (Anguispira stronglyodes, Mesomphix friabilis, Olygyra orbiculata y …

Gambling On Genes: Ambiguity Aversion Explains Investment In Sisters' Children, Brishti Guha

Research Collection School Of Economics

Many men invest in their sisters’ children instead of their wives’. Existing theories addressing such behavior depend on the level of paternity probability in such men’s societies being implausibly low. I link this anthropologically observed investment behavior with the experimentally observed phenomenon that some individuals are ambiguity averse. Arguing that men’s decisions are made under ambiguity, I show that an increase in ambiguity aversion results in investment in sisters’, rather than wives’, children. I show that this can happen even under risk neutrality. I also consider the special cases of a SEU maximizer and of extreme ambiguity aversion in the …

The Effects Of Coaching On Situational Judgment Tests In High-Stakes Selection, Filip Lievens, Tine Buyse, Paul R. Sackett, Brian S. Connelly

Research Collection Lee Kong Chian School Of Business

Although the evidence for the use of situational judgment tests (SJTs) in high-stakes testing has been generally promising, questions have been raised regarding the potential coachability of SJTs. This study reports the first examination of the effects of coaching on SJT scores in an operational high-stakes setting. We contrast findings from a simple comparison of SJT scores for coached and uncoached participants (posttest only) with three different approaches to deal with the effects of self-selection into coaching programs, namely using a pretest as a covariate and using two different forms of propensity score-based matching using a wide range of variables …

Defending The Castle: Integrated Pest Management In High Tunnel Strawberries, Tiffany Maughan, Taunya Ernst, Brent Black, Daniel Drost

All Current Publications

In recent years, the use of high tunnels for extending the growing season has become fairly widespread. High tunnels operate and look like greenhouses (Image 1), but are passively heated and cooled which helps keep operating costs low.

September 2012 News Releases, University Of Montana--Missoula. Office Of University Relations

University of Montana News Releases, 1928, 1956-present

No abstract provided.

Evaluation Of Persistence And Relative Toxicity Of Some Pest Control Products To Adults Of Two Native Trichogrammatid Species In Kenya, G. Momanyi, R. Maranga, S. Sithanantham, S. Agong, C. M. Matoka, S. A. Hassan

All Peer-Reviewed Publications

The utilization of native trichogrammatids for biocontrol of Helicoverpa armigera (Hbn.) and their potential integration with pesticide use are currently receiving attention. In this study the interaction of adults of Trichogramma sp. nr. mwanzai and Trichogrammatoidea sp. nr. lutea with commonly used pesticide products was investigated. The toxicity of eight pest control products commonly used in vegetable crops in Kenya, were evaluated by exposing the adults of the two species to detached potted tomato leaves at different intervals after spraying. Two biologically derived products, Achook ® (neem-based) and Dipel ® (Bt ssp. kurstaki)-were found to be harmless and had no …

Biosynthetic Pathways And The Role Of The Mas Receptor In The Effects Of Angiotensin-(1-7) In Smooth Muscles., Marcio Augusto Fressatto De Godoy, Larissa Pernomian, Ana Maria De Oliveira, Satish Rattan

Department of Medicine Faculty Papers

Ang-(1-7) is produced via degradation of Ang II by the human angiotensin converting enzyme, also known as ACE2. In the cardiovascular system, Ang-(1-7) has been shown to produce effects that are opposite to those of Ang II. These include smooth muscle relaxation and cardioprotection. While the roles of Ang-(1-7) in other systems are currently topic of intense research, functional data suggest a relaxation action in gastrointestinal smooth muscles in a way that corroborates the results obtained from vascular tissues. However, more studies are necessary to determine a relevant role for Ang-(1-7) in the gastrointestinal system. The Ang-(1-7) actions are mediated …

Graphene-Coated Substrates For Biochemical And Optoelectronic Applications, Amrita Banerjee

Dissertations

Graphene - monolayer or a few layers of graphite -- has proven to possess remarkable properties: large thermal conductivity, mechanical robustness, two-dimensional ultra large electronic mobility, chemical inertness and biochemical compatibility. Realization of some applications has been impeded by lack of a large area deposition method. By using a novel methodology to deposit graphene on solid and perforated substrates, various optoelectronic and biochemical elements have been demonstrated in this thesis: (1) graphene based transistors were fabricated and their characteristics were assessed. The mobility for such transistors exceeded 5000 cm2/V·s, much larger than their silicon based counterparts. Such attribute opens up …

High Aspect Ratio Electrodes For High Yield Electroporation Of Cells, Anil B. Shrirao

Dissertations

Electroporation is a widely used process in cell biology studies. It uses an electric field to create pores on the cell membrane in order to either insert exogenous molecules inside the cells or disrupt the cell membrane to kill the cells. Current micro-fluidic electroporation devices use the planar electrodes situated at the bottom of a microchannel. These planar electrodes i) require a high voltage and ii) generate a nonuniform electric field which result in low yield of the electroporation. The standard silicon microfabrication technologies are not suitable to fabricate non-planar electrodes required to increase the yield of electroporation.

In this …

Use Of Quantitative Membrane Proteomics Identifies A Novel Role Of Mitochondria In Healing Injured Muscles., Nimisha Sharma, Sushma Medikayala, Sree Rayavarapu, Kristy J. Brown, Yetrib Hathout, Jyoti K. Jaiswal, Aurelia Defour

Pediatrics Faculty Publications

Skeletal muscles are proficient at healing from a variety of injuries. Healing occurs in two phases, early and late phase. Early phase involves healing the injured sarcolemma and restricting the spread of damage to the injured myofiber. Late phase of healing occurs a few days postinjury and involves interaction of injured myofibers with regenerative and inflammatory cells. Of the two phases, cellular and molecular processes involved in the early phase of healing are poorly understood. We have implemented an improved sarcolemmal proteomics approach together with in vivo labeling of proteins with modified amino acids in mice to study acute changes …

The Echo: August 31, 2012, Taylor University

2012-2013 (Volume 100)

Taylor Community Saves Polar Pops – Contraceptive Controversy Continues – Up to code: field house revealed – Top 5 News Events of the Week – Rentals and E-books Gain Popularity – DCs and Das join Residence Life – In The Loop – Weekly Forecast – Local Speedway provides fun for more than 16 years – Prayer for the masses – Al-Assad, Syria’s con man – International doctors undercover – Around the World – Looking into Euler – Jury serves historic verdict: Apply awarded $1B in patent dispute – Through curiosity’s eyes – Remembering Adam Such – Community Plunge – Where …

Increasing Community Participation With Self-Organizing Meeting Processes, Philip H. Howard

Journal of Rural Social Sciences

Involving many people in community-based research provides many benefits, such as more labor power and increased buy-in. Traditional meeting formats, however, are not well suited to attracting broad engagement. One way to address this challenge is to instead employ self-organizing meeting processes, which are designed to invite active participation from attendees, and do not predefine the agenda. This article describes three such processes, 1) Open Space Technology, 2) World Café, and 3) Dynamic Facilitation, followed by my observations on their advantages and disadvantages when employed in community-based research efforts. Their use requires giving up a great amount of control when …

"In Space" Or "As Space"?: A New Model, Charles H. Smith, Megan Derr

DLPS Faculty Publications

In this analysis natural systems are posed to subsystemize in a manner facilitating both structured information/energy sharing and an entropy maximization process projecting a three-dimensional, spatial, outcome. Numerical simulations were first carried out to determine whether n × n input-output matrices could, once entropymaximized, project a three-dimensional Euclidean metric. Only 4 × 4 matrices could; a small proportion passed the test. Larger proportions passed when grouped random patterns on and within two- and three-dimensional forms were tested. Topographical patterns within 31 stream basin systems in the state of Kentucky, USA, were then similarly investigated, anticipating that the spatial configuration of …

Human Endometrial Stromal Stem Cells Differentiate Into Megakaryocytes With The Ability To Produce Functional Platelets, Jinju Wang, Shuzhen Chen, Cheng Zhang, Samantha Stegeman, Teresa Pfaff-Amesse, Ying Zhang, Wenfeng Zhang, Lawrence Amesse, Yanfang Chen

Pharmacology and Toxicology Faculty Publications

Human endometrium is a high dynamic tissue that contains endometrial stromal stem cells (hESSCs). The hESSCs have been differentiated into a number of cell lineages. However, differentiation of hESSCs into megakaryocytes (MKs) has not yet been investigated. The aim of this study was to investigate the feasibility of MK generation from hESSCs and subsequent production of functional platelets (PLTs). In our study, hESSCs were cultured from endometrial stromal cells as confirmed by positive stromal cell specific markers (CD90 and CD29) and negative hematopoietic stem cell markers (CD45 and CD34) expression. Then, hESSCs were differentiated in a medium supplemented with thrombopoietin …

Adrenal Steroids Uniquely Influence Sexual Motivation Behavior In Male Rats, George Taylor, Joshua Dearborn, Susan Maloney

Psychology Faculty Works

The androgenic adrenal steroids dehydroepiandrosterone (DHEA) and 4α-androstenedione (4-A) have significant biological activity, but it is unclear if the behavioral effects are unique or only reflections of the effects of testosterone (TS). Gonadally intact male Long-Evans rats were assigned to groups to receive supplements of DHEA, 4-A, TS, corticosteroid (CORT), all at 400 µg steroid/kg of body weight, or vehicle only for 5 weeks. All males were tested in a paradigm for sexual motivation that measures time and urinary marks near an inaccessible receptive female. It was found that DHEA and 4-A supplements failed to influence time near the estrous …

The Wooster Voice (Wooster, Oh), 2012-08-31, Wooster Voice Editors

The Voice: 2012-Present

The headlining article "Class of 2016: Most selective class yet" talks about the challenges of the tough enrollment process for the 2012-2013 year. "Beall Avenue's new stoplight will monitor foot traffic" details the newly added crosswalk signals to alleviate traffic issues between Lowry and the Libraries, as well as staff needed to act as crossing guards. Other news stories are on a new judicial board to assess Greek Life members, the new APEX program in Gault Library, and dinner returning to Kittredge Hall. The Features section includes articles on a graduate's non-profit to help indegenious Chileans and encouragement for students …

Today - August 31, 2012, Loma Linda University

TODAY

Inside this issue:

-- School of Dentistry opens Hugh Love Center for Research & Education in Technology
-- CMS team positive after visiting various Loma Linda health care entities
-- Advanced imaging and microscopy core facility celebrates first anniversary
-- SPH professor speaks on chronic diseases at Pan American Forum
-- Dentistry professor wins first place in poster competition at NIH event
-- Third-year pharmacy student attends seminar at University of Utah
-- American Board of Operative Dentistry elects dentistry professor as president
-- School of Dentistry alumnus volunteers among the Maasai
-- Gateway program introduces teens to health careers …

Early Invasion Of Brain Parenchyma By African Trypanosomes, Ute Frevert, Alexandru Movila, Olga V. Nikolskaia, Jayne Raper, Zachary B. Mackey, Maha Abdulla, James Mckerrow, Dennis J. Grab

Publications and Research

Human African trypanosomiasis or sleeping sickness is a vector-borne parasitic disease that has a major impact on human health and welfare in sub-Saharan countries. Based mostly on data from animal models, it is currently thought that trypanosome entry into the brain occurs by initial infection of the choroid plexus and the circumventricular organs followed days to weeks later by entry into the brain parenchyma. However, Trypanosoma brucei bloodstream forms rapidly cross human brain microvascular endothelial cells in vitro and appear to be able to enter the murine brain without inflicting cerebral injury. Using a murine model and intravital brain imaging, …

Soundings 2012-08-31, N/A N/A

Soundings

No abstract provided.

Hemorrhage Detection And Analysis In Traumatic Pelvic Injuries, Pavani Davuluri

Theses and Dissertations

Traumatic pelvic injuries associated with high-energy pelvic fractures are life-threatening injuries. Extensive bleeding is relatively common with pelvic fractures. However, bleeding is especially prevalent with high-energy fractures. Hemorrhage remains the major cause of death that occur within the first 24 hours after a traumatic pelvic injury. Emergent-life saving treatment is required for high-energy pelvic fractures associated with hemorrhage. A thorough understanding of potential sources of bleeding within a short period is essential for diagnosis and treatment planning. Computed Tomography (CT) images have been widely in use in identifying the potential sources of bleeding. A pelvic CT scan contains a large …

Property Rights For Natural Resources Management In Indonesia: Have They Been Ruled Unconstitutional?, Sarah Waddell

Indonesia Law Review

A new property right known as the coastal waters commercial use right (Hak Pengusahaan Pengairan Pesisir (HP-3)) introduced by Law No. 27 of 2007 regarding the Management of Coastal and Small Island Areas has been ruled inoperative by the Constitutional Court. The decision raises a question as to whether the door has been closed to marketbased instruments that rely on property rights as a policy tool in natural resources management. This concern is relevant as legal developments in natural resources law internationally have moved away from traditional forms of regulation to focus on the creation of new statutory property rights …

Database Of Diazotrophs In Global Ocean: Abundance, Biomass And Nitrogen Fixation Rates, Y.-W. Luo, S.C. Doney, L.A. Anderson, M. Benavides, I. Berman-Frank, A. Bode, S. Bonnet, K. H. Boström, D. Böttjer, D.G. Capone, E.J. Carpenter, Y.L. Chen, M.J. Church, J.E. Dore, L.I. Falcón, A. Fernández, R.A. Foster, K. Furuya, F. Gómez, K. Gundersen, A.M. Hynes, D.M. Karl, S. Kitajima, R.J. Langlois, J. Laroche, R.M. Letelier, E. Marañón, D.J. Mcgillicuddy Jr., P.H. Moisander, C.M. Moore, B. Mouriño-Carballido, M.R. Mulholland, J.A. Needoba, K.M. Orcutt, A.J. Poulton, E. Rahav, P. Raimbault, A.P. Rees, L. Riemann, T. Shiozaki, A. Subramaniam, T. Tyrell, K.A. Turk-Kubo, M. Varela, T.A. Villareal, E.A. Webb, A.E. White, J. Wu, J.P. Zehr

Faculty Publications

Marine N₂ fixing microorganisms, termed diazotrophs, are a key functional group in marine pelagic ecosystems. The biological fixation of dinitrogen (N₂) to bioavailable nitrogen provides an important new source of nitrogen for pelagic marine ecosystems and influences primary productivity and organic matter export to the deep ocean. As one of a series of efforts to collect biomass and rates specific to different phytoplankton functional groups, we have constructed a database on diazotrophic organisms in the global pelagic upper ocean by compiling about 12 000 direct field measurements of cyanobacterial diazotroph abundances (based on microscopic cell counts or …

News Of The Department Of Animal Science, Department Of Animal Science

Animal Science Newsletters

No abstract provided.

Role Of Nf-KB Signaling In Multiple Myeloma, Rachel Rajavi Pallapati

Master's Theses and Doctoral Dissertations

Genomic DNA was purified from Multiple Myeloma Cell Line JJN3, and BMF promoter region was PCR amplified and cloned into pCR 2.1 TOPO vector using One Shot® Chemically Competent E. coli. After confirmation of the clone through polymerase chain reaction (PCR) and restriction analysis, BMF promoter (2.5 Kb) was released from TOPO vector and subcloned into pGL3 promoter vector. The resulting pGL3-BMF-promoter vector was further amplified for MaxiPrep preparation. This plasmid can be used to study the regulation of BMF promoter by various transcription factors including NF-κB family members.

Examining The Affects Of Four Mental Images On Student Dancers' Jumping Height, Teresa Heiland

Dance Faculty Works

A quasi-experimental design was used to assess effects of Franklin Method images on dancers’ jump height. Thirteen dancers applied four image interventions while performing first position jumps for vertical height analysis. Mean heights and within-trial jump degradation and variability were examined. A repeated-measures mixed model analysis with covariates was used to assess whether jump heights differed significantly from baseline. Two of the four images showed significant increases in jump height above baseline. A linear time effect was also found over the course of the study. Anecdotal self-reports revealed that there appeared to be no correlation between jump height and imagery …