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Transcriptomic Analysis Of Peritoneal Cells In A Mouse Model Of Sepsis: Confirmatory And Novel Results In Early And Late Sepsis., Minny Bhatty, Ruping Fan, William M. Muir, Stephen B. Pruett, Bindu Nanduri

Department of Animal Sciences Faculty Publications

Background

The events leading to sepsis start with an invasive infection of a primary organ of the body followed by an overwhelming systemic response. Intra-abdominal infections are the second most common cause of sepsis. Peritoneal fluid is the primary site of infection in these cases. A microarray-based approach was used to study the temporal changes in cells from the peritoneal cavity of septic mice and to identify potential biomarkers and therapeutic targets for this subset of sepsis patients.

Results

We conducted microarray analysis of the peritoneal cells of mice infected with a non-pathogenic strain of Escherichia coli. Differentially expressed …

The Greatest Book You Will Never Read: Public Access Rights And The Orphan Works Dilemma, Libby Greismann

Duke Law & Technology Review

Copyright law aims to promote the dual goals of incentivizing production of literary and artistic works, and promoting public access and free speech. To achieve these goals, Congress has implemented a policy that acknowledges the rights of both the copyright holder and the public, which vest with the fixation of the work. However, as Congressional action has strengthened copyright protection, the rights of the public have been narrowed. Orphan works – works to which the copyright owner cannot be located or identified – present a unique problem, in that achieving free access and use of the works is often impossible. …

Genetics Of Sle: Functional Relevance For Monocytes/Macrophages In Disease, Jennifer C. Byrne, Joan Ní Gabhann, Elisa Lazzari, Rebecca Mahony, Siobhán Smith, Kevin Stacey, Claire Wynne, Caroline A. Jefferies

Articles

Genetic studies in the last 5 years have greatly facilitated our understanding of how the dysregulation of diverse components of the innate immune system contributes to pathophysiology of SLE. A role for macrophages in the pathogenesis of SLE was first proposed as early as the 1980s following the discovery that SLE macrophages were defective in their ability to clear apoptotic cell debris, thus prolonging exposure of potential autoantigens to the adaptive immune response. More recently, there is an emerging appreciation of the contribution both monocytes and macrophages play in orchestrating immune responses with perturbations in their activation or regulation leading …

Semester Abroad At Avignon, Julie Hughes

Letters from Returnees: Sharing the Value of Study Abroad

This letter from returnee Julie Hughes explains the value of studying abroad in France.

Lanthorn, Vol. 47, No. 11, September 24, 2012, Grand Valley State University

Volume 47, July 2, 2012 - June 3, 2013

Lanthorn is Grand Valley State's student newspaper, published from 1968 to the present.

The Statesman, V. 56, I. 04, Stony Brook University

Stony Brook Statesman-Sucolian

v. 56, i. 04

Current, September 24, 2012, University Of Missouri-St. Louis

Current (2010s)

No abstract provided.

Columbia Chronicle (09/24/2012), Columbia College Chicago

Columbia Chronicle

Student newspaper from September 24, 2012 entitled The Columbia Chronicle. This issue is 44 pages and is listed as Volume 48, Number 4. Cover story: "Acclaimed alumnit to visit Columbia" Editor-in-Chief: Heather Schröering

Intronic Rnas Constitute The Major Fraction Of The Non-Coding Rna In Mammalian Cells, Georges St. Laurent, Dmitry Shtokalo, Michael R. Tackett, Zhaoqing Yang, Tatyana Eremina, Claes Wahlestedt, Silvio Urcuqui-Inchima, Bernd Seilheimer, Timothy A. Mccaffrey, Philipp Kapranov

Medicine Faculty Publications

Background

The function of RNA from the non-coding (the so called “dark matter”) regions of the genome has been a subject of considerable recent debate. Perhaps the most controversy is regarding the function of RNAs found in introns of annotated transcripts, where most of the reads that map outside of exons are usually found. However, it has been reported that the levels of RNA in introns are minor relative to those of the corresponding exons, and that changes in the levels of intronic RNAs correlate tightly with that of adjacent exons. This would suggest that RNAs produced from the vast …

Almaliach V. State, Edna Arbel, Zvi Zylbertal, Uzi Vogelman

Translated Opinions

Facts: The appellant was convicted of the crimes of carrying a weapon, intimidation, and possession of stolen property. The indictment charged that in the early morning hours of December 2, 2006, in the city of Ashdod, the appellant carried a stolen grenade into a building in which the Biton family resided, and then taped the grenade to a piece of cardboard which he then taped to the Biton family‘s front door, leaving a string tied to the grenade‘s safety mechanism. He ran away after a family member woke up and opened the door. The indictment was based on DNA evidence …

Centromere Remodeling In Hoolock Leuconedys (Hylobatidae) By A New Transposable Element Unique To The Gibbons, Lucia Carbone, R. Alan Harris, Alan R. Mootnick, Aleksandar Milosavljevic, David I.K. Martin, Mariano Rocchi, Oronzo Capozzi, Nicoletta Archidiacono, Miriam K. Konkel, Jerilyn A. Walker, Mark A. Batzer, Pieter J. De Jong

Faculty Publications

Gibbons (Hylobatidae) shared a common ancestor with the other hominoids only 15-18 million years ago. Nevertheless, gibbons show very distinctive features that include heavily rearranged chromosomes. Previous observations indicate that this phenomenon may be linked to the attenuated epigenetic repression of transposable elements (TEs) in gibbon species. Here we describe the massive expansion of a repeat in almost all the centromeres of the eastern hoolock gibbon (Hoolock leuconedys). We discovered that this repeat is a new composite TE originating from the combination of portions of three other elements (L1ME5, AluSz6, and SVA-A) and thus named it LAVA. We determined that …

Pyrosequencing-Based Analysis Of The Microbiome Associated With The Horn Fly, Haematobia Irritans, Azhahianambi Palavesam, Felix D. Guerrero, Andrew M. Heekin, Ju Wang, Scot E. Dowd, Yan Sun, Lane D. Foil, Adalberto A. Pérez De León

Faculty Publications

The horn fly, Haematobia irritans, is one of the most economically important pests of cattle. Insecticides have been a major element of horn fly management programs. Growing concerns with insecticide resistance, insecticide residues on farm products, and non-availability of new generation insecticides, are serious issues for the livestock industry. Alternative horn fly control methods offer the promise to decrease the use of insecticides and reduce the amount of insecticide residues on livestock products and give an impetus to the organic livestock farming segment. The horn fly, an obligatory blood feeder, requires the help of microflora to supply additional nutrients and …

The Collegian (2012-09-24), Joe Molina

UTB/TSC Archives - The Collegian [Newspaper]

Vol. 65, No. 5

Parameters – Full Issue, Usawc Parameters

The US Army War College Quarterly: Parameters

American Landpower and the Middle East of 2030 by Micael R. Eastman. The Afghanistan Experience: Democratization by Force, by Cora Sol Goldstein. COIN is Dead–Long Live Transformation, by Matthew Ford, Patrick Rose, and Howard Body. Afghanistan: Strategy and War Termination, by Christopher Tuck. The Futility of Force and the Preservation of Power: British Strategic failure in America 1780-1783. by Daniel T. Canfield. The Internet, New Media, and the Evolution of Insurgency, by Steven Metz

Gwu Honors Students Participate In Nc Big Sweep, Office Of University Communications

Gardner-Webb NewsCenter Archive

One of the oldest rivers in the world recently received a helping hand from Gardner-Webb University honors students as they participated in an annual environmental clean up event. Over 60 students, faculty members, and volunteers took part in the annual New River clean up day, held Sept. 8 in Ashe County, N.C. The initiative is coordinated by North Carolina Big Sweep, an organization whose purpose is to rid the environment of litter by promoting environmental education and organizing annual statewide cleanup efforts of waterways and other areas.

Grand Valley Forum, Volume 037, Number 05, September 24, 2012, Grand Valley State University

2012-2013, Volume 37

Grand Valley Forum is Grand Valley State's faculty and staff newsletter, published from 1976 to the present.

Crow's Nest, September 24, 2012, Crow's Nest Staff

Crow's Nest

The September 24, 2012, issue of the Crow's Nest.

Weight Gain, Metabolic Syndrome, And Breast Cancer Recurrence: Are Dietary Recommendations Supported By The Data?, Colin E Champ, Jeff S Volek, Joshua Siglin, Lianjin Jin, Nicole L Simone

Department of Radiation Oncology Faculty Papers

Metabolic syndrome, which can include weight gain and central obesity, elevated serum insulin and glucose, and insulin resistance, has been strongly associated with breast cancer recurrence and worse outcomes after treatment. Epidemiologic and prospective data do not show conclusive evidence as to which dietary factors may be responsible for these results. Current strategies employ low-fat diets which emphasize supplementing calories with increased intake of fruit, grain, and vegetable carbohydrate sources. Although results thus far have been inconclusive, recent randomized trials employing markedly different dietary strategies in noncancer patients may hold the key to reducing multiple risk factors in metabolic syndrome …

The Free Press Vol 44 Issue 3, 09-24-2012, Kirsten Sylvain

Free Press, The

Reel Big Fish needs a real big crowd--Gray and Dodge talk Libertarian platform--Faculty complaints about development cuts--Student Senate last Friday

The Bg News September 24, 2012, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. September 24, 2012. Volume 103-Issue 17.

Medical School Watercooler Newsletter - September 23, 2012, Lindsey Lyle

Watercooler Newsletter

This is the September 23, 2012 edition of the Frederick P. Whiddon College of Medicine's newsletter - Watercooler.

Contents Include:

• Final Flu Shot Clinics to be Held Friday
• Dr. Mary Burtnick Receives Research Award
• USMLE Step 1 Results Show USA Medical Students Score Above National Average
• Tailgating for Autism This Weekend
• Next Week's DSS - Dr. Roger Simon
• Drs. Franks, Perkins Featured on Local News

Mother Goats Do Not Forget Their Kids’ Calls, Elodie F. Briefer, Mónica Padilla De La Torre, Alan G. Mcelligott

Sentience Collection

Parent–offspring recognition is crucial for offspring survival. At long distances, this recognition is mainly based on vocalizations. Because of maturation-related changes to the structure of vocalizations, parents have to learn successive call versions produced by their offspring throughout ontogeny in order to maintain recognition. However, because of the difficulties involved in following the same individuals over years, it is not clear how long this vocal memory persists. Here, we investigated long-term vocal recognition in goats. We tested responses of mothers to their kids’ calls 7–13 months after weaning. We then compared mothers’ responses to calls of their previous kids with …

2012 Annual Dinner Program, The O'Callahan Society, College Of The Holy Cross

O'Callahan Society Annual Dinner Program

Twelfth in a series of speaker events sponsored by the O'Callahan Society at its annual dinner. The keynote speaker is Rear Admiral Garry J. Bonelli, Deputy Commander, Naval Special Warfare Command. The evening's program also pays tribute to the Navy SEALS on the fiftieth anniversary of their establishment in 1962.

Rhetorical Research: Methods For Teaching Multiple Purposes For Texts, Phyllis Ryder, Shannon Berry

Georgia International Conference on Information Literacy

See presentation description.

Cal Poly To Host Sustainable Pest Management Conference Dec. 7-8, Public Affairs Office

Press Releases

No abstract provided.

Volume 48 - Issue 03 - Friday, September 21, 2012, Rose Thorn Staff

The Rose Thorn Archive

The Rose Thorn, Rose-Hulman's independent student newspaper.

Soft Microenvironments Promote The Early Neurogenic Differentiation But Not Self-Renewal Of Human Pluripotent Stem Cells, Albert Keung, Prashanth Asuri, Sanjay Kumar, David Schaffer

Bioengineering

Human pluripotent stem cells (hPSCs) are of great interest in biology and medicine due to their ability to self-renew and differentiate into any adult or fetal cell type. Important efforts have identified biochemical factors, signaling pathways, and transcriptional networks that regulate hPSC biology. However, recent work investigating the effect of biophysical cues on mammalian cells and adult stem cells suggests that the mechanical properties of the microenvironment, such as stiffness, may also regulate hPSC behavior. While several studies have explored this mechanoregulation in mouse embryonic stem cells (mESCs), it has been challenging to extrapolate these findings and thereby explore their …

Undergraduate Schedule Of Classes For 2012, Fall [West Campus] | Academic Calendar | Class Schedule, Office Of The Registrar, Stony Brook University

Calendars

No abstract provided.

Academic Calendar | School Of Professional Development For 2012, Fall [West Campus] | Class Schedule, Office Of The Registrar, Stony Brook University

Calendars

No abstract provided.

Academic Calendar | Undergraduate Schedule Of Classes For 2012, Fall [Southampton] | Class Schedule, Office Of The Registrar, Stony Brook University

Calendars

No abstract provided.