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Synthesis Of Knowledge On Tremolite In Talc, Chantal Dion, Guy Perrault, Mounia Rhazi

États de la question, rapports d’expertise et revues de littérature

Le talc est largement utilisé dans différents milieux de travail, notamment dans les secteurs de la céramique, des peintures (peinture antirouille), des composés à joint pour gypse, des cosmétiques, du plastique et du caoutchouc. Puisque certains talcs peuvent contenir des amphiboles dont la trémolite, possiblement sous la morphologie asbestiforme (ou fibreuse) et non asbestiforme (fragments de clivage), il est important d'en connaître la provenance et la composition afin de mettre en place des stratégies de surveillance de l'exposition et des moyens de prévention adéquats pour les travailleurs et autres utilisateurs.

Plusieurs définitions et applications du terme amiante sont utilisées pour …

Synthèse Des Connaissances Sur La Trémolite Contenue Dans Le Talc, Chantal Dion, Guy Perrault, Mounia Rhazi

États de la question, rapports d’expertise et revues de littérature

Le talc est largement utilisé dans différents milieux de travail, notamment dans les secteurs de la céramique, des peintures (peinture antirouille), des composés à joint pour gypse, des cosmétiques, du plastique et du caoutchouc. Puisque certains talcs peuvent contenir des amphiboles dont la trémolite, possiblement sous la morphologie asbestiforme (ou fibreuse) et non asbestiforme (fragments de clivage), il est important d'en connaître la provenance et la composition afin de mettre en place des stratégies de surveillance de l'exposition et des moyens de prévention adéquats pour les travailleurs et autres utilisateurs.

Plusieurs définitions et applications du terme amiante sont utilisées pour …

Gera Conference Program [2012], Gera

Georgia Educational Research Association Conference

Conference program for 2012.

The Hospital’S Role Within A Regional Disaster Response: A Comparison Study Of An Urban Hospital Versus A Rural Hospital, Ali Alshehri

Theses

The goal of this research is to evaluate the hospital's role in a regional disaster response. It focuses on identifying the level of the hospital's preparedness and its response to disasters and includes a comparison study between an urban and a rural hospital in New York state. The findings of this work show some differences between the urban and rural hospitals in terms of their capabilities and available resources and the effect of the community infrastructures on their preparedness. Both hospitals have similarities in the way participants view the hospital's role during a regional disaster response. It is noted that …

Hospital As A Critical Infrastructure In The Community Disaster Response System, Yixuan Li

Theses

The Department of Homeland Security lists 19 groups of sectors as Critical Infrastructure Key Resources (CIKR) such as Water, Emergency Services, and Healthcare and Public Health (HPH). Protection of those interdependent sectors is of vital interest for the country in the event of disaster. Hospital infrastructure systems are basic HPH elements of the CIKR. Local hospitals deliver essential routine healthcare services as well as serving as frontline responders during non-routine disaster events. Currently, hospitals generally extend their routine healthcare activities for external community disaster preparedness and response services. This extension takes the form of coordination with other responders within the …

Synthesis Of A Difluorometric Cross-Membrane Molecular Probe For Studying Amphipathic Systems, Danielle Raymond

Theses

A surfactant is an amphiphile which consists of a hydrophobic and hydrophilic end. In nonpolar solvents containing a small amount of water surfactants can form reverse micelles. Extensive research has been done using fluorescent probes to study several properties of these amphiphilic aggregates including mechanism of formation, critical micelle concentration, aggregate number and size, nanopolarity, and viscosity. Dr. Langner's group at RIT proposed the structure of a difluorometric, ratiometric probe that can transverse the membrane of a reverse micelle created in a system of decane/water/AOT/butyl alcohol. This probe has a dansyl and a coumarin portion making it amphiphilic and could …

A Preliminary Study On The Potential Of Manuka Honey And Platelet-Rich Plasma In Wound Healing, Scott A. Sell, Patricia S. Wolfe, Andrew J. Spence, Isaac A. Rodriguez, Jennifer M. Mccoll, Rebecca L. Petrella, Koyal Garg, Jeffery J. Ericksen, Gary L. Bowlin

Ellmer School of Nursing Faculty Publications

Aim. The purpose of this study was to determine the in vitro response of cells critical to the wound healing process in culture media supplemented with a lyophilized preparation rich in growth factors (PRGF) and Manuka honey. Materials and Methods. This study utilized cell culture media supplemented with PRGF, as well as whole Manuka honey and the medical-grade Medihoney (MH), a Manuka honey product. The response of human fibroblasts (hDF), macrophages, and endothelial cells (hPMEC) was evaluated, with respect to cell proliferation, chemotaxis, collagen matrix production, and angiogenic potential, when subjected to culture with media containing PRGF, MH, Manuka honey, …

A Chemical Proteomic Probe For Detecting Dehydrogenases: Catechol Rhodanine, Xia Ge, Daniel S. Sem

Chemistry Faculty Research and Publications

The inherent complexity of the proteome often demands that it be studied as manageable subsets, termed subproteomes. A subproteome can be defined in a number of ways, although a pragmatic approach is to define it based on common features in an active site that lead to binding of a common small molecule ligand (ex. a cofactor or a cross-reactive drug lead). The subproteome, so defined, can be purified using that common ligand tethered to a resin, with affinity chromatography. Affinity purification of a subproteome is described in the next chapter. That subproteome can then be analyzed using a common ligand …

How Selective Is Social Learning In Dolphins?, Stan A. Kuczaj Ii, Deirdre Yeater, Lauren Highfill

Psychology Faculty Publications

Social learning is an important aspect of dolphin social life and dolphin behavioral development. In addition to vocal social learning, dolphins discover behaviors for foraging, play, and social interactions by observing other members of their social group. But dolphins neither indiscriminately observe nor mindlessly mimic other dolphins. To the contrary, dolphin calves are quite selective in their choices of who to observe and/or imitate. Calves are most likely to learn foraging behaviors from their mothers, but they are more likely to watch and reproduce the play behaviors of other calves than the play behaviors of adult dolphins (including their mothers). …

Strategies Of Cooperation And Punishment Among Students And Clerical Workers, Maria Bigoni, Gabriele Camera, Marco Casari

ESI Working Papers

We study the individual behavior of students and workers in an experiment where they repeatedly face the same cooperative task. The data show that clerical workers differ from college students in overall cooperation rates, strategy adoption and use of punishment opportunities. Students cooperate more than workers. Cooperation increases in both subject pools when a personal punishment option is available. Students are less likely than workers to adopt strategies of unconditional defection, and more likely to select strategies of conditional cooperation. Finally, students are more likely than workers to sanction uncooperative behavior by adopting decentralized punishment, and also personal punishment when …

Building And Rebuilding Trust With Promises And Apologies, Eric Schniter, Roman M. Sheremeta, Daniel Sznycer

ESI Working Papers

Using trust games, we study how promises and messages are used to build new trust where it did not previously exist and to rebuild damaged trust. In these games, trustees made non-binding promises of investment-contingent returns, then investors decided whether to invest, and finally trustees decided how much to return. After an unexpected second game was announced, but before it commenced, trustees could send a one-way message. This design allowed us to observe the endogenous emergence and natural distribution of trust-relevant behaviors and focus on naturally occurring remedial strategies used by promise-breakers and distrusted trustees, their effects on investors, and …

Why Can’T We Be Friends? Entitlements, Bargaining, And Conflict, Erik O. Kimbrough, Roman M. Sheremeta

ESI Working Papers

We design an experiment to explore the impact of earned entitlements on the frequency and intensity of conflicts in a two-stage conflict game with side-payments. In this game, residents (Proposers) make side-payment offers and contestants (Responders) decide whether to accept the offers and whether to engage in a conflict. When subjects earn their roles, conflicts are 44% more likely to be avoided than when roles are assigned randomly. Earned rights impact behavior in three important ways: (1) residents who have earned their position persistently offer larger side-payments; (2) larger offers lead to a lower probability of conflict, but (3) residents …

Side-Payments And The Costs Of Conflict, Erik O. Kimbrough, Roman M. Sheremeta

ESI Working Papers

Conflict and competition often impose costs on both winners and losers, and conflicting parties may prefer to resolve the dispute before it occurs. The equilibrium of a conflict game with side-payments predicts that with binding offers, proposers make and responders accept side-payments, generating settlements that strongly favor proposers. When side-payments are non-binding, proposers offer nothing and conflicts always arise. Laboratory experiments confirm that binding side-payments reduce conflicts. However, 30% of responders reject binding offers, and offers are more egalitarian than predicted. Surprisingly, non-binding side-payments also improve efficiency, although less than binding. With binding side-payments, 87% of efficiency gains come from …

Role Of Extracytoplasmic Function Sigma Factors In Porphyromonas Gingivalis, Suhasini Yanamandra Sai

Theses and Dissertations

Porphyromonas gingivalis is a major etiological agent that is responsible for the cause and progression of periodontal diseases. The bacterium is exposed to various environmental conditions and oxidative stress conditions while it is in the oral cavity. So, P. gingivalis should have an efficient regulatory system in order to adjust and survive in the oral cavity. But little is known about the regulatory mechanisms that help the bacteria to survive in the oral cavity. So, it is essential to understand and characterize these regulatory mechanisms. The response and adaptation of P. gingivalis to environmental stress conditions occur at the level …

The Role Of R7 Regulators Of G Protein Signaling In The Retina, Hoon Shim

Theses and Dissertations

The R7 regulators of G protein signaling (R7 RGS), namely RGS6, RGS7, RGS9 and RGS11, are expressed in the retina along with its binding partner Gβ5. The RGS9-1 isoform is expressed only in retinal photoreceptors and rate-limits the recovery of rod phototransduction by acting as a member of the transducin GAP complex (RGS9-1/Gβ5L/R9AP). The Gβ5L isoform is also only expressed in retinal photoreceptors and acts by stabilizing the GAP complex. The Gβ5S isoform differs from Gβ5L by the absence of exon 1 due to alternative splicing and is expressed in many other retinal cells. Gβ5L is barely detectable in RGS9-/- …

Designing Direct And Indirect Factor Xa Inhibitors, Rami Al-Horani

Theses and Dissertations

Anticoagulants are the basis for treatment and prevention of thrombotic diseases. The currently available medicines are associated with a wide range of adverse reactions that mandates developing new anticoagulants. Several lines of evidence support the superiority of factor Xa (FXa) as a promising target to develop novel anticoagulants. This work focuses on the design of direct and indirect FXa inhibitors using an interdisciplinary approach. As indirect FXa inhibitors, a focused library of tetrasulfated N–arylacyl tetrahydroisoquinoline (THIQ) nonsaccharide allosteric antithrombin activators was designed, synthesized, and biochemically evaluated to establish their structure–activity relationship (SAR). An N–arylacyl THIQ analog having carboxylate at position–3, …

Investigating The Role Of Α6 And Α4 Containing Neuronal Nicotinic Acetylcholine Receptors In Nicotine And Cocaine Conditioned Place Preference Tests In Mice., Sarah Sanjakdar

Theses and Dissertations

Neuronal nicotinic acetylcholine receptors modulate both cholinergic and non-cholinergic synaptic transmission. Our research concerns α6 and α4 neuronal nicotinic subunits because they often co-assemble with the β2 subunit, which has abundant expression in the CNS and previous work has demonstrated that β2* nAChRs are involved in nicotine and cocaine reward. α6β2* and α4β2* nAChRs are highly expressed in midbrain, which is known to be critical for the incentive salience associated with natural and artificial (drug) reward. Our goal was to assess the role of α6β2* and α4β2* nAChRs in nicotine and cocaine reward using an unbiased conditioned place preference (CPP) …

Identifying Sortase A Variants With Higher Catalytic Effeciency, Muna Suliman

Theses and Dissertations

In the past two decades, the field of protein engineering has evolved rapidly to include new genetic and chemical techniques to alter protein function. Protein engineering seeks to improve enzyme properties through powerful methods that specifically incorporate novel or improved function in proteins. One such method is protein ligation, which is used to selectively link synthetic and recombinant polypeptides. Due to the limitations of current protein labeling techniques, simple site-specific modification methods remain in high demand. Use of enzyme-based labeling has been the focus of various studies because of its substrate specificity. Sortase-mediated transpeptidation is one approach that has been …

Regeneration Of Electrospun Bioresorbable Vascular Grafts: A Phenomenon Associated With Vascular Graft Properties And Macrophage Phenotypes (M1/M2), Koyal Garg

Theses and Dissertations

Macrophages (MФ) and mast cells are important cell types in the context of tissue remodeling and regeneration. Mast cells participate in the early stages of wound healing and modulate the acute inflammatory responses to biomaterials. Mast cells can secrete a myriad of different cytokines by the process of degranulation; the process of regulated secretion in which preformed contents stored in their granules are rapidly released by exocytosis. Some of these cytokines such as IL-4, IL-13 and TNF-α can modulate the MФ phenotype. Macrophages (MΦ) are innate immune cells, crucial for tissue homeostasis, presentation of foreign and self-antigens following infection/injury, pathogen …

Novel Fluorous Hybrid Surface Modification Characterized By Wetting Dynamics, Morphology And Nanomechanics, Sithara Nair

Theses and Dissertations

The surface response of a polymer substrate to external stimuli such as initial wetting is controlled by the outermost molecular layer. Thus, changes on the nanoscale may be engaged to control macroscale wetting behavior. Our work has predominantly focused on surface modification of conventional polyurethane coatings (HMDI-BD-PTMO). Studies on network constrained phase separation and facile polydimethylsiloxane surface functionalization led to the discovery of a simpler one-step and more general approach to functional polymer surfaces that we have designated as “Bottle-Brush Nanoglass” (BB-NG) after the two principle components: (a) a polyoxetane soft block “spine” with side chain “A” bristles and triethoxysilyl …

Structure Of Mandelate Racemase With Bound Intermediate Analogues Benzohydroxamate And Cupferron, Adam D. Lietzan, Mitesh Nagar, Elisa Pellmann, Jennifer R. Bourque, Stephen L. Bearne, Martin St. Maurice

Biological Sciences Faculty Research and Publications

Mandelate racemase (MR, EC 5.1.2.2) from Pseudomonas putida catalyzes the Mg2+-dependent interconversion of the enantiomers of mandelate, stabilizing the altered substrate in the transition state by 26 kcal/mol relative to the substrate in the ground state. To understand the origins of this binding discrimination, we determined the X-ray crystal structures of wild-type MR complexed with two analogues of the putative aci-carboxylate intermediate, benzohydroxamate and Cupferron, to 2.2-Å resolution. Benzohydroxamate is shown to be a reasonable mimic of the transition state and/or intermediate because its binding affinity for 21 MR variants correlates well with changes in the free energy of transition …

Developmental Expression Of Drop-Dead Is Required For Early Adult Survival And Normal Body Mass In Drosophila Melanogaster, Christine Lynn Sansone, Edward M. Blumenthal

Biological Sciences Faculty Research and Publications

In Drosophila melanogaster, mutations in the gene drop-dead (drd) result in early adult lethality, with flies dying within 2 weeks of eclosion. Additional phenotypes include neurodegeneration, tracheal defects, starvation, reduced body mass, and female sterility. The cause of early lethality and the function of the drd protein remain unknown. In the current study, the temporal profiles of drd expression required for adult survival and body mass regulation were investigated. Knockdown of drd expression by UAS-RNAi transgenes and rescue of drd expression on a drd mutant background by a UAS-drd transgene were controlled with the Heat Shock Protein …

Savanna Glade Hotspots: Plant Community Development And Synergy With Large Herbivores, Kari E. Veblen

Wildland Resources Faculty Publications

In African savannas, abandonment of traditional livestock corrals (bomas) creates long-term mosaics of nutrient hotspots embedded in a lower-nutrient matrix. It is unclear how plant communities develop over time on these sites in clay-rich “black cotton” soils or how herbivores attracted to these sites affect vegetation development. I first examined whether treeless “glades”, derived from abandoned bomas, function as nutrient and herbivore hotspots. Soil, vegetation, and herbivore data were collected on glades of varying ages. The results indicated that glades persist as long-term (≥four decades) patches (0.25–1.0 ha) of improved soil texture and increased nutrient levels, palatable grasses, and herbivore …

Introduction, Establishment, And Spread: 50 Years Of Invasion Ecology Since Elton, Karen H. Beard, Andrew Kulmatiski

Wildland Resources Faculty Publications

While some may argue that Charles Elton was not a "founder" but rather a "prophet" of invasion ecology (Simberloff, this volume), Elton’s 1958 monograph The ecology of invasions by animals and plants (Methuen, London) inspired and informed many of today’s ecologists about the issues and problems of biological invasions. In addition, while many theories Elton proposed in his monograph (e.g., diversityinvasibility) have been questioned and his oversights (e.g., on propagule pressure) have been noted, there is no doubt that he has influenced entire directions of research. Thus, revisiting Elton’s influence on the field of invasion ecology 50 years after his …

Plant-Soil Feedbacks Provide An Alternative Explanation For Diversity-Productivity Relationships, Andrew Kulmatiski, Karen H. Beard, Justin Heavilin

Wildland Resources Faculty Publications

Plant–soil feedbacks (PSFs) have gained attention for their role in plant community dynamics, but their role in productivity has been overlooked. We developed and tested a biomass-specific, multi-species model to examine the role of PSFs in diversity–productivity relationships. The model predicts a negative relationship between PSFs and overyielding: plants with negative PSFs grow more in communities than in monoculture (i.e. overyield), and plants with positive PSFs grow less in communities than in monoculture (i.e. underyield). This effect is predicted to increase with diversity and saturate at low species richness because the proportion of ‘self-cultivated’ soils rapidly decreases as species are …

A New Ensemble Learning Method For Temporal Pattern Identification, Wenjing Zhang, Xin Feng

Electrical and Computer Engineering Faculty Research and Publications

In this paper we present a method for identification of temporal patterns predictive of significant events in a dynamic data system. A new hybrid model using Reconstructed Phase Space (MRPS) and Hidden Markov Model (HMM) is applied to identify temporal patterns. This method constructs phase space embedding by using individual embedding of each variable sequences. We also employ Hidden Markov Models (HMM) to the multivariate sequence data to categorize multi-dimensional data into three states, e.g. normal, patterns and events. A support vector machine optimization method is used to search an optimal classifier to identify temporal patterns that are predictive of …

A Semantic Foundation For Provenance Management, Sudha Ram, Jun Liu

Research & Publications

Provenance is a term used to describe the lineage, history, or origin of an object. While provenance originated from the artworld, it is now becoming increasingly important in the context of digital objects on the World Wide Web. Large scale scientific collaborations and social media platforms on the web have enabled production and sharing of a variety of digital objects on the web. With the proliferation and sharing of such objects, which include documents, pictures, videos, and more, questions such as “where did this object come from?”, “who else is using this object?” and “for what purpose was it generated?” …

He Loves The Immigrant: Deuteronomy's Theological And Social Vision For The Ger, Mark Abraham Awabdy

ATS Dissertations

No abstract provided.

2012 Weed Science Research Report – Blue Section, Ndsu Weed Science, Dept. Of Plant Sciences

Plant Sciences Weed Science Reports

The Weed Science team at North Dakota State University conduct field research in the State of North Dakota. This specific document reports on field research conducted in 2012. It includes work on corn, soybean and the management of several weeds in North Dakota.

Comparative Microbial Sampling From Eutrophic Caves In Slovenia And Slovakia Using Rida ®Count Test Kits, Janez Mulec, Václav Krištůfek, Alica Chroňáková

International Journal of Speleology

RIDA®COUNT test plates were used as an easy-to-handle and rapid indicator of microbial counts in karst ecosystems of several caves in Slovakia and Slovenia. All of the caves had a high organic input from water streams, tourists, roosting bat colonies or terrestrial surroundings. We sampled swabs, water and air samples to test robustness and universality of the RIDA®COUNT test kit (R-Biopharm AG, Germany, http://www.r-biopharm.com/) for quantification of total bacteria, coliforms, yeast and mold. Using data from swabs (colony-forming units per cm²) we proposed a scale for description of biocontamination level or superficial microbial load of cave niches. Based …