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2012

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State Sovereignty And Self-Defense In Cyberspace: A Normative Framework For Balancing Legal Rights, Catherine Lotrionte Jan 2012

State Sovereignty And Self-Defense In Cyberspace: A Normative Framework For Balancing Legal Rights, Catherine Lotrionte

Emory International Law Review

Today's threats recognize no national boundaries, are connected, and must be addressed at the global and regional as well as the national levels. When warranted, [the United States] will respond to hostile acts in cyberspace as we would to any other threat to our country. All states possess an inherent right to self-defense . . . . [We recognize] that hostile acts conducted through cyberspace could compel actions under the commitments we have with our military treaty partners . . . America must also face the rapidly growing threat from cyber-attacks. Now, we know hackers steal people's identities and infiltrate …

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Giving Teeth To European Patent Reform: Overcoming Recent Legal Challenges, Matthew Parker Jan 2012

Giving Teeth To European Patent Reform: Overcoming Recent Legal Challenges, Matthew Parker

Emory International Law Review

Europe must transition from a national, splintered patent enforcement regime to a transnational, uniform patent enforcement regime to protect the value of European patents in the global economy. Patent reform in Europe is ongoing and supported by most member states of the European Union (EU), but objections by the European Court of Justice (ECJ), the European Parliament, Spain, and Italy have stymied progress. This Comment proposes modifications to patent reform in an effort to overcome these myriad objections and to enable the realization of meaningful European patent reform.

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Conformational And Thermodynamic Properties Modulate The Nulceotide Excision Repair Of 2-Aminofluorene And 2-Acetylaminofluorene Dg Adducts In The Nari Sequence, Vipin Jain, Benjamin Hilton, Satyakam Patnaik, Yue Zou, M. Paul Chiarelli, Bongsup P. Cho Jan 2012

Conformational And Thermodynamic Properties Modulate The Nulceotide Excision Repair Of 2-Aminofluorene And 2-Acetylaminofluorene Dg Adducts In The Nari Sequence, Vipin Jain, Benjamin Hilton, Satyakam Patnaik, Yue Zou, M. Paul Chiarelli, Bongsup P. Cho

Chemistry: Faculty Publications and Other Works

Nucleotide excision repair (NER) is a major repair pathway that recognizes and corrects various lesions in cellular DNA. We hypothesize that damage recognition is an initial step in NER that senses conformational anomalies in the DNA caused by lesions. We prepared three DNA duplexes containing the carcinogen adduct N-(2'-deoxyguanosin-8-yl)-7-fluoro-2-acetylaminofluorene (FAAF) at G(1), G(2) or G(3) of NarI sequence (5'-CCG(1)G(2)CG(3)CC-3'). Our (19)F-NMR/ICD results showed that FAAF at G(1) and G(3) prefer syn S- and W-conformers, whereas anti B-conformer was predominant for G(2). We found that the repair of FAAF occurs in a conformation-specific manner, i.e. the highly S/W-conformeric G(3) and -G(1) …

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Returning Genetic Research Results: Considerations For Existing No-Return And Future Biobanks, Karen J. Maschke Jan 2012

Returning Genetic Research Results: Considerations For Existing No-Return And Future Biobanks, Karen J. Maschke

Minnesota Journal of Law, Science & Technology

No abstract provided.

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Using Participatory Scenarios To Stimulate Social Learning For Collaborative Sustainable Development, Kris A. Johnson, Genya Dana, Nicholas R. Jordan, Kathy J. Draeger, Anne Kapuscinski Jan 2012

Using Participatory Scenarios To Stimulate Social Learning For Collaborative Sustainable Development, Kris A. Johnson, Genya Dana, Nicholas R. Jordan, Kathy J. Draeger, Anne Kapuscinski

Dartmouth Scholarship

Interdependent human and biophysical systems are highly complex and behave in unpredictable and uncontrollable ways. Social and ecological challenges that emerge from this complexity often defy straightforward solutions, and efforts to address these problems will require not only scientific and technological capabilities but also learning and adaptation. Scenarios are a useful tool for grappling with the uncertainty and complexity of social-ecological challenges because they enable participants to build adaptive capacity through the contemplation of multiple future possibilities. Furthermore, scenarios provide a platform for social learning, which is critical to acting in the face of uncertain, complex, and conflict-laden problems. We …

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The Formin Fmnl3 Is A Cytoskeletal Regulator Of Angiogenesis, Clare Hetheridge, Alice N. Scott, Rajeeb K. Swain, John W. Copeland, Henry N. Higgs Jan 2012

The Formin Fmnl3 Is A Cytoskeletal Regulator Of Angiogenesis, Clare Hetheridge, Alice N. Scott, Rajeeb K. Swain, John W. Copeland, Henry N. Higgs

Dartmouth Scholarship

The process of angiogenesis requires endothelial cells (ECs) to undergo profound changes in shape and polarity. Although this must involve remodelling of the EC cytoskeleton, little is known about this process or the proteins that control it. We used a co-culture assay of angiogenesis to examine the cytoskeleton of ECs actively undergoing angiogenic morphogenesis. We found that elongation of ECs during angiogenesis is accompanied by stabilisation of microtubules and their alignment into parallel arrays directed at the growing tip. In other systems, similar microtubule alignments are mediated by the formin family of cytoskeletal regulators. We screened a library of human …

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A Seminaphthofluorescein-Based Fluorescent Chemodosimeter For The Highly Selective Detection Of Cysteine, Xiaofeng Yang, Yixing Guo, Robert M. Strongin Jan 2012

A Seminaphthofluorescein-Based Fluorescent Chemodosimeter For The Highly Selective Detection Of Cysteine, Xiaofeng Yang, Yixing Guo, Robert M. Strongin

Chemistry Faculty Publications and Presentations

A fluorescent chemodosimeter for cysteine detection was developed based on a tandem conjugate addition and intramolecular cyclization reaction. The method exhibited an excellent selectivity for cysteine over other biothiols such as homocysteine and glutathione.

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Wilderness, Water, And Climate Change, Sandra B. Zellmer Jan 2012

Wilderness, Water, And Climate Change, Sandra B. Zellmer

Faculty Law Review Articles

As the nation searches for climate mitigation and adaptation strategies, the pressure to develop water resources within wilderness areas and to exploit the timber, forage, wildlife, fish, and other virtually untapped components of wilderness will become more acute. This Article makes the case that managers and legislatures should not yield to this pressure and argues that, if anything, the need to preserve untrammeled wilderness characteristics is just as imperative today as it was in 1964 when the Wilderness Act was passed The Article examines the potency of the Wilderness Act and a trio of federal water law doctrines-federally reserved water …

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Beyond Spacetime Geometry – The Death Of Philosophy And Its Quantum Reincarnation, Wen-Ran Zhang Jan 2012

Beyond Spacetime Geometry – The Death Of Philosophy And Its Quantum Reincarnation, Wen-Ran Zhang

Computer Science: Faculty Publications

Contrary to the “end” and “death” assertions on philosophy, this paper predicts an equilibrium-based and harmony-centered scientific reincarnation of philosophy. Logically, the reincarnation is backed by a formal system and a background independent geometry that transcends spacetime. Physically, it is supported by definable quantum causality and bipolar logical unifications of matter and antimatter, particle and wave, big bang and black hole, relativity and quantum entanglement. Philosophically, it is distinguished from Western metaphysics and dialectics as well as the Dao of Laozi. It is named a quantum reincarnation for its central claim that YinYang bipolar quantum entanglement is the source of …

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Novel Techniques Of Using Diversity In Software Security And Information Hiding, Jin Han Jan 2012

Novel Techniques Of Using Diversity In Software Security And Information Hiding, Jin Han

Dissertations and Theses Collection (Open Access)

Diversity is an important and valuable concept that has been adopted in many fields to reduce correlated risks and to increase survivability. In information security, diversity also helps to increase both defense capability and fault tolerance for information systems and communication networks, where diversity can be adopted from many different perspectives. This dissertation, in particular, focuses mainly on two aspects of diversity – the application software diversity and the diversity in data interpretation. Software diversity has many advantages over mono-culture in improving system security. A number of previous researches focused on utilizing existing off-theshelf diverse software for network protection and …

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Assessment Of Motor Functioning In The Preschool Period, Jan Piek, Beth P. Hands, Melissa Licari Jan 2012

Assessment Of Motor Functioning In The Preschool Period, Jan Piek, Beth P. Hands, Melissa Licari

Health Sciences Papers and Journal Articles

The assessment of motor functioning in young children has become increasingly important in recent years with the acknowledgement that motor impairment is linked with cognitive, language, social and emotional difficulties. However, there is no one gold standard assessment tool to investigate motor ability in children. The aim of the current paper was to discuss the issues related to the assessment of motor ability in young pre-school children and to provide guidelines on the best approach for motor assessment. The paper discusses the maturational changes in brain development at the preschool level in relation to motor ability. Other issues include sex …

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Gender Bias In The Technical Disciplines, Jessica Lynn Campbell Jan 2012

Gender Bias In The Technical Disciplines, Jessica Lynn Campbell

Electronic Theses and Dissertations

This study investigates how women are affected by gender bias in the workplace. Despite the increasing numbers of women in the workforce, women are still under-represented and under-valued in workplaces, which, in part, is due to their gender stereotype. This study demonstrates how gender bias in the workplace has been proven to limit women in their careers and potential in their occupational roles. The media’s negative depiction of women in their gender stereotype reinforces and perpetuates this image as a cultural norm in society. Women both conform and are judged and evaluated according to their weak and submissive gender stereotype. …

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Examining Gender In Pharmaceutical Rhetoric Through A Cultural Studies Lens: A Case Study On The Gardasil Vaccine, Jennifer Fickley-Baker Jan 2012

Examining Gender In Pharmaceutical Rhetoric Through A Cultural Studies Lens: A Case Study On The Gardasil Vaccine, Jennifer Fickley-Baker

Electronic Theses and Dissertations

On June 8, 2006, Merck announced the debut of Gardasil, the world's first vaccine found successful in preventing human papillomavirus (HPV) infections, a sexually transmitted infection that is one of the main causes of certain cancers in men and women, including cervical, vulvar, penile and anal cancers. To promote the vaccine's release, Merck launched Gardasil's "One Less" advertising campaign that included television commercials, print ads and a consumerfocused website (www.Gardasil.com), each promoting the message that "you" could now be "one less woman" affected by cervical cancer ("One Less" campaign). The vaccine, tested and approved only for females age 9-26, was …

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The Foods And Crops Of The Muisca: A Dietary Reconstruction Of The Intermediate Chiefdoms Of Bogota (Bacata) And Tunja (Hunza), Colombia, Jorge Luis Garcia Jan 2012

The Foods And Crops Of The Muisca: A Dietary Reconstruction Of The Intermediate Chiefdoms Of Bogota (Bacata) And Tunja (Hunza), Colombia, Jorge Luis Garcia

Electronic Theses and Dissertations

The Muisca people of the Eastern Cordillera of Colombia had an exceptionally complex diet, which is the result of specific subsistence strategies, environmental advantages, and social restrictions. The distinct varieties of microclimates, caused by the sharp elevations in this part of the Andes, allows for a great biodiversity of plants and animals that was accessible to the native population. The crops of domesticated and adopted plants of the Muisca include a wide variety of tubers, cereals, fruits, and leaves that are described in detail in this thesis. The Muisca used an agricultural method known as microverticality where the different thermic …

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Educating Gifted Students With Asperger's Syndrome: A Case Study Of Three Students And Their Classroom Experiences, Beverly S. Horn Jan 2012

Educating Gifted Students With Asperger's Syndrome: A Case Study Of Three Students And Their Classroom Experiences, Beverly S. Horn

Electronic Theses and Dissertations

Much research has focused on students with Asperger’s Syndrome (AS), and much research has also been done on gifted students with special needs, yet very little has been published that looks at the characteristics of students who have been identified as both Gifted and as having Asperger Syndrome (G/AS), and what teachers are doing in the classroom to meet their needs. This is an important topic because this group of twice exceptional students has characteristics of both exceptionalities, and trying to meet the special needs of both groups in the same classroom would likely be a challenge for the teacher. …

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Stable Isotopes And Multiple Tissue Analysis: Reconstructing Life Histories For Individuals From Dakhleh Oasis, Egypt, Noel Johns Jan 2012

Stable Isotopes And Multiple Tissue Analysis: Reconstructing Life Histories For Individuals From Dakhleh Oasis, Egypt, Noel Johns

Electronic Theses and Dissertations

Stable isotope analysis is often used to evaluate elements of the lives of past peoples, such as diet and health status, at a societal level. Analysis at an individual level is exceptionally rare, and has not been conducted using a variety of tissues representing both early life and life approximate to death. In this study, δ 13C and δ15N isotope signatures are used to create life histories for single individuals from Romano-Christian period Kellis 2 cemetery in the Dakhleh Oasis, Egypt. Samples are obtained from several different tissues, including tooth dentin, bone collagen, hair, nail, skin, and gut content, all …

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Deconstructing Disability, Assistive Technology: Secondary Orality, The Path To Universal Access, Tara Prakash Tripathi Jan 2012

Deconstructing Disability, Assistive Technology: Secondary Orality, The Path To Universal Access, Tara Prakash Tripathi

Electronic Theses and Dissertations

When Thomas Edison applied for a patent for his phonograph, he listed the talking books for the blind as one of the benefits of his invention. Edison was correct in his claim about talking books or audio books. Audio books have immensely helped the blind to achieve their academic and professional goals. Blind and visually impaired people have also been using audio books for pleasure reading. But several studies have demonstrated the benefits of audio books for people who are not defined as disabled. Many nondisabled people listen to audio books and take advantage of speech based technology, such as …

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Classroom Based Substance Use Prevention Programs: A Meta-Analysis, Alyssa R. Boucher Jan 2012

Classroom Based Substance Use Prevention Programs: A Meta-Analysis, Alyssa R. Boucher

Electronic Theses and Dissertations

This paper reports on a meta-analysis performed on forty one studies evaluating classroom-based substance abuse primary prevention programs. Studies included were delivered in a classroom to the general student body, had a primary focus of substance abuse prevention, measured behavior change, and were published in peer-reviewed outlets between 2000 and 2011. Comprehensive Meta-Analysis was used to calculate a random effects Cohen’s d and moderator analyses. Results indicated a significant effect for alcohol (d=0.10) and tobacco (d=0.09) in multi-target interventions. Specific program components and characteristics associated with more effective prevention programs are discussed. Despite the best efforts of those who develop …

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The Impact Of Timed Versus Untimed Standardized Tests On Reading Scores Of Third Grade Students In Title I Schools, Ruth Elizabeth Haniff Jan 2012

The Impact Of Timed Versus Untimed Standardized Tests On Reading Scores Of Third Grade Students In Title I Schools, Ruth Elizabeth Haniff

Electronic Theses and Dissertations

The purpose of this study was to investigate the extent to which the performance of Title I third grade students in a central Florida School District differed on tests administered under timed and untimed conditions. Further examined was the literature on reasons for the achievement gap which centered around seven different themes: (a) standardized testing, (b) achievement gap data and identified factors (c) deficit theory, (d) cultural mismatch theory, (e) extended time accommodations, (f) test anxiety and stress, and (g) timed versus untimed tests. Six Title I schools participated in this study by assigning 194 students to take the 2006 …

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Foreclosures And Crime: Testing Social Disorganization Theory In The Suburbs, Sara Hoskin Jan 2012

Foreclosures And Crime: Testing Social Disorganization Theory In The Suburbs, Sara Hoskin

Electronic Theses and Dissertations

Foreclosures have increased in the US since the 1970’s. The increase in foreclosures has caused concern among some researchers on their affect on crime. Social disorganization theory measures the effect various structural characteristics, such as poverty, residential instability/mobility, racial/ethnic heterogeneity, and family disruption have on crime. This study, though, is concerned with residential instability/mobility, or the presence of foreclosed houses in neighborhoods. Although most studies using this theory look at low-income neighborhoods, the following research looks at middle- and upper-income neighborhoods, which have been greatly affected by foreclosures. The theory also argues that the level of collective efficacy can reduce …

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Comorbidity Of Psychopathy In Schizotypy: Skin Conductance To Affective Pictures, Kathleen A. Ragsdale Jan 2012

Comorbidity Of Psychopathy In Schizotypy: Skin Conductance To Affective Pictures, Kathleen A. Ragsdale

Electronic Theses and Dissertations

Prior research substantiates a relationship between psychopathy and schizophrenia-spectrum disorders, which has begun to elucidate why some individuals with schizophrenia are violent. Unfortunately, this relationship has been limited to self-report. To objectively corroborate this finding, undergraduate students were recruited from an online screening administration of the Schizotypal Personality Questionnaire. This resulted in 56 participants (52% male) with a mean age of 20.37 (SD = 4.74) and a wide range of schizotypy scores who participated in the experiment. Following completion of self-report measures, participants viewed 15 pictures (five neutral, five threatening, and five of others in distress) from the International Affective …

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Examination Of An Online College Mathematics Course: Correlation Between Learning Styles And Student Achievement, Bridget Steele Jan 2012

Examination Of An Online College Mathematics Course: Correlation Between Learning Styles And Student Achievement, Bridget Steele

Electronic Theses and Dissertations

The purpose of this study was to determine if there was a significant relationship between learning styles and student learning outcomes in an online college mathematics course. Specifically, the study was guided by two research questions focused on (a) the extent to which learning styles had a predictive relationship with student achievement in an online college mathematics course and (b) the extent to which various learning styles among mathematics students in online versus face-to-face courses predicted mathematics achievement. The population for this study consisted of the 779 college mathematics and algebra (CMA) students who were enrolled in a private multimedia …

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The Effects Of Phosphatidylserine On Reaction Time And Cognitive Function Following An Exercise Stress, Adam John Wells Jan 2012

The Effects Of Phosphatidylserine On Reaction Time And Cognitive Function Following An Exercise Stress, Adam John Wells

Electronic Theses and Dissertations

Phosphatidylserine (PS) is an endogenously occurring phospholipid that has been shown to have cognition and mood enhancing properties in humans, possibly through its role as an enzyme co-factor in cellular signal transduction. Specifically, PS has been identified as activator of classical isoforms of protein kinase C, an enzyme known to be involved in the growth and differentiation of neural cells, and is therefore thought to play a role in the protection of neurons. The purpose of this study was to examine the effects of supplementation with PS and caffeine on measures of cognition, reaction time and mood prior to and …

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Phosphatidic Acid Increases Lean Body Tissue And Strength In Resistance Trained Men, David Williams Jan 2012

Phosphatidic Acid Increases Lean Body Tissue And Strength In Resistance Trained Men, David Williams

Electronic Theses and Dissertations

Phosphatidic Acid (PA) is a natural phospholipid compound derived from lecithin which is commonly found in egg yolk, grains, fish, soybeans, peanuts and yeast. It has been suggested that PA is involved in several intracellular processes associated with muscle hypertrophy. Specifically, PA has been reported to activate protein synthesis through the mammalian target of rapamycin (mTOR) signaling pathway and thereby may enhance the anabolic effects of resistance training. To our knowledge, no one has examined the effect of PA supplementation in humans while undergoing a progressive resistance training program. To examine the effect of PA supplementation on lean soft tissue …

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A Wolf In Military Clothing: A Case Study Examination Of Lone Wolf Terrorism And The Roles And Responsibilities Of Government Agencies, Peter Bandel Jan 2012

A Wolf In Military Clothing: A Case Study Examination Of Lone Wolf Terrorism And The Roles And Responsibilities Of Government Agencies, Peter Bandel

Electronic Theses and Dissertations

Since the fall of September, 2011, there has been a major increase in awareness and study of global terrorism. Academia, the media, politicians, and the average citizen all have varying definitions, ideas, and concerns about terrorism. The focus has mainly been on international terrorism. Terrorist organizations like Al Qaeda have permeated the discussion. However, there is a growing concern of the "lone wolf terrorist." A lone wolf terrorist acts without a terrorist organization and is capable of having his/her own radical agenda with the audacity and simplicity to carry it out solely and enact great damage. The focus in the …

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Quantifying The Impacts Of Oyster Reef Restoration On Oyster Coverage, Wave Attenuation And Seagrass Fragment Retention In Mosquito Lagoon, Florida, Stephanie Garvis Jan 2012

Quantifying The Impacts Of Oyster Reef Restoration On Oyster Coverage, Wave Attenuation And Seagrass Fragment Retention In Mosquito Lagoon, Florida, Stephanie Garvis

Electronic Theses and Dissertations

The goal of this project was to determine the effects of oyster reef restoration on oyster coverage, wave height dissipation and seagrass recruitment. First, to assess the current versus historical coverage of natural, dead and restored oyster reefs within Mosquito Lagoon, aerial photographs from 2009, provided by Saint Johns River Water Management District, were digitized using ArcGIS software. Live reefs, restored reefs and dead reefs were screen digitized using a reef ‘signature’ in order to estimate the area of each type of reef. The 2009 maps were used as a guide to digitizing the historical aerial photographs (1943, 1951, 1967, …

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Expression Of Lipase From Mycobacterium Tuberculosis In Nicotiana Tobacum And Lactuca Sativa Chloroplasts, Bethany Lloyd Jan 2012

Expression Of Lipase From Mycobacterium Tuberculosis In Nicotiana Tobacum And Lactuca Sativa Chloroplasts, Bethany Lloyd

Electronic Theses and Dissertations

Tuberculosis (TB), caused by the bacterium Mycobacterium tuberculosis (M. tuberculosis), is a global threat and the leading cause of death among individuals infected with HIV. TB treatment requires multi-drug cocktails, due to the increasing rates of drug resistance of the bacterium. With multi-drug cocktails, strains have been documented to be resistant to all major drugs in the fight against TB. Since the strains are drug resistant, it calls for an increasing need for vaccine and treatment development for the purpose of preventing and managing the disease. The most widely distributed vaccine against TB is Bacillus Calmette-Gue´rin (BCG). Apart from being …

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Selective Multivariate Applications In Forensic Science, Caitlin Rinke Jan 2012

Selective Multivariate Applications In Forensic Science, Caitlin Rinke

Electronic Theses and Dissertations

A 2009 report published by the National Research Council addressed the need for improvements in the field of forensic science. In the report emphasis was placed on the need for more rigorous scientific analysis within many forensic science disciplines and for established limitations and determination of error rates from statistical analysis. This research focused on multivariate statistical techniques for the analysis of spectral data obtained for multiple forensic applications which include samples from: automobile float glasses and paints, bones, metal transfers, ignitable liquids and fire debris, and organic compounds including explosives. The statistical techniques were used for two types of …

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Cerium Oxide Nanoparticles Act As A Unique Catalyst And Scavenge Nitric Oxide And Peroxynitrite And Decrease Rns In Vitro And In Vivo, Janet Dowding Jan 2012

Cerium Oxide Nanoparticles Act As A Unique Catalyst And Scavenge Nitric Oxide And Peroxynitrite And Decrease Rns In Vitro And In Vivo, Janet Dowding

Electronic Theses and Dissertations

Cerium oxide nanoparticles (CeO2 NPs)(nanoceria) have been shown to possess a substantial oxygen storage capacity via the interchangeable surface reduction and oxidation of cerium atoms, cycling between the Ce4+ and Ce3+ redox states. Reduction of Ce4+ to Ce3+ causes oxygen vacancies or defects on the surface of the crystalline lattice structure of the particles, generating a cage for redox reactions to occur. The study of the chemical and biological properties of CeO2 NPs has expanded recently, and the methods used to synthesize these materials are also quite diverse. This has led to a plethora of studies describing various preparations of …

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A Study Of The Degradative Capabilities Of The Bimetallic System: Mg(Pd/C) As Applied In The Destruction Of Decafluoropentane, An Environmental Contaminant, Douglas Tomlin Jan 2012

A Study Of The Degradative Capabilities Of The Bimetallic System: Mg(Pd/C) As Applied In The Destruction Of Decafluoropentane, An Environmental Contaminant, Douglas Tomlin

Electronic Theses and Dissertations

Pollution from hydrofluorocarbons (HFC) poses a serious challenge to the environmental community. Released from industrial operations, they have contaminated both the atmosphere and groundwater and are considered persistent in both media.1 For over the past 20 years, the practice of synthesizing hydrofluorocarbons as alternatives to chlorofluorocarbons (CFC) has been conducted in an effort to reverse the effects of stratospheric ozone layer depletion. 2,3 However, in doing so these new fluorinated compounds exhibited an unexpected property as a potent global warming greenhouse gas (GHG) with radiative forcing potentials in the range of 100 to 10,000 equivalents greater than carbon dioxide.4 Conversely, …

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