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2012

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Molecular Mechanisms Involved In Inflammatory Angiogenesis Induced By Monocyte Chemotactic Protein Induced Protein-1 (Mcpip1), Arpita Roy Jan 2012

Molecular Mechanisms Involved In Inflammatory Angiogenesis Induced By Monocyte Chemotactic Protein Induced Protein-1 (Mcpip1), Arpita Roy

Electronic Theses and Dissertations

Major diseases such as cardiovascular diseases, diabetes, obesity and tumor growth are known to involve inflammatory angiogenesis. MCP-induced protein 1 (MCPIP1) encoded by ZC3H12A gene, was reported to promote angiogenesis and is addressed in my dissertation as MCPIP. The mechanism/s involved in the angiogenic differentiation induced by MCPIP was however unknown. The aim of this study was to bridge this gap in our knowledge and delineate the molecular mechanisms and sequential processes involved in angiogenesis mediated via MCPIP. To determine if angiogenesis induced by inflammatory cytokines, TNF-, IL-1 and IL-8 is mediated via induction of MCPIP, knockdown of MCPIP by …


Infraded Surface Plasmon Polaritons On Semiconductor, Semimetal And Conducting Polymer, Monas Shahzad Jan 2012

Infraded Surface Plasmon Polaritons On Semiconductor, Semimetal And Conducting Polymer, Monas Shahzad

Electronic Theses and Dissertations

Conductors with IR (infrared) plasma frequencies are potentially useful hosts of surface plasmon polaritons (SPPs) with subwavelength mode confinement for sensing applications. The underlying aim of this work is to identify such conductors that also have sharp SPP excitation resonances for biosensor applications at infrared (3-11 m) wavelengths, where biological analytes are strongly differentiated by their IR absorption spectra. In this work, various materials were investigated such as a heavily doped semiconductor, a semimetal, a conducting polymer and its composite. Heavily doped silicon was investigated by tuning its plasma frequency to the infrared region by heavily doping. The measured complex …


The Behavior Of Cerium Oxide Nanoparticles In Polymer Electrolyte Membranes In Ex-Situ And In-Situ Fuel Cell Durability Tests, Benjamin Pearman Jan 2012

The Behavior Of Cerium Oxide Nanoparticles In Polymer Electrolyte Membranes In Ex-Situ And In-Situ Fuel Cell Durability Tests, Benjamin Pearman

Electronic Theses and Dissertations

Fuel cells are known for their high efficiency and have the potential to become a major technology for producing clean energy, especially when the fuel, e.g. hydrogen, is produced from renewable energy sources such as wind or solar. Currently, the two main obstacles to wide-spread commercialization are their high cost and the short operational lifetime of certain components. Polymer electrolyte membrane (PEM) fuel cells have been a focus of attention in recent years, due to their use of hydrogen as a fuel, their comparatively low operating temperature and flexibility for use in both stationary and portable (automotive) applications. Perfluorosulfonic acid …


Landscaping Perceptions And Behaviors: Socio-Ecological Drivers Of Nitrogen In The Residential Landscape, Leesa Souto Jan 2012

Landscaping Perceptions And Behaviors: Socio-Ecological Drivers Of Nitrogen In The Residential Landscape, Leesa Souto

Electronic Theses and Dissertations

Driven by individual influences such as beliefs, attitudes, personal norms, and abilities, as well as by social influences like community norms, mandates, and the market, suburban homeowners are motivated to select and maintain a turf grass landscape. In many areas of Florida, effective suburban lawn maintenance requires regular inputs of nitrogenous fertilizer, some of which is lost to the environment, contributing to water quality degradation and ecosystem dysfunction. Reducing nitrogen inputs to aquatic systems requires a better understanding of the links between residential landscape management and the potential for fertilizer loss. This dissertation examines the linkages between the human behaviors …


Examination Of Mediational Models Of The Hostility-Health Link, Carol Goulet Jan 2012

Examination Of Mediational Models Of The Hostility-Health Link, Carol Goulet

Graduate Theses, Dissertations, and Problem Reports (ETD)

This study investigated health behavior as a possible mediator of the link between hostility and poor physical and psychological health. The relations of health behavior, character strength, and virtuous behavior to hostility and health were also examined. A sample of 689 undergraduate participants (69.4% female) completed a series of on-line assessments that measured hostility, physical health, psychological health, health behavior, social support, character strength, and virtuous behavior. Health behavior was examined and found to be a significant partial mediator of the relations between hostility and physical and psychological health. Furthermore, the results of multiple regressions revealed that gender, hostility, and …


A Question Of Life Or Death: Suicide And Survival In The Union Army, Kathleen Anneliese Logothetis Jan 2012

A Question Of Life Or Death: Suicide And Survival In The Union Army, Kathleen Anneliese Logothetis

Graduate Theses, Dissertations, and Problem Reports (ETD)

Studying the Civil War soldier involves a quest to comprehend how they soldiers understood and managed their war experiences. Under the conditions of soldier life and the horrific violence of Civil War battles, mental trauma and suicide would not be unthinkable consequences. Union soldiers did commit suicide during the war, sometimes in response to the trauma of battle, hospital, or prison camp. However, suicide in fact was a very small percentage of casualties in the Union army, representing less than one percent of the losses during the war.;This thesis examines the dual nature of suicide in the Union army. On …


Evaluation Of Novel Sigma Receptor Antagonists Against Meth-Induced Neurotoxicity: In Vivo And In Vitro Studies, Nidhi Kaushal Jan 2012

Evaluation Of Novel Sigma Receptor Antagonists Against Meth-Induced Neurotoxicity: In Vivo And In Vitro Studies, Nidhi Kaushal

Graduate Theses, Dissertations, and Problem Reports (ETD)

Methamphetamine (METH) is a highly addictive psychostimulant drug of abuse, causing hyperthermia and neurotoxicity at high doses. Currently, there is no clinically proven pharmacotherapy to treat these effects of METH, necessitating identification of potential novel therapeutic targets. Earlier studies showed that METH binds to sigma receptors in the brain at physiologically relevant concentrations, where it acts in part as an agonist. AC927 (1-(2-phenethyl)piperidine oxalate), CM156 (3-(4-(4-cyclohexylpiperazin-1-yl)butyl)benzo[d]thiazole-2(3H)-thione) and SN79 (6-acetyl-3-(4-(4-(4-florophenyl)piperazin-1-yl)butyl)benzo[d]oxazol-2(3H)-one) were synthesized as putative sigma receptor antagonists with nanomolar affinity and selectivity for sigma receptors over 29-80 other binding sites. AC927, CM156 and SN79 pretreatment afforded protection against METH-induced hyperthermia and …


Pharmacological Characterization Of Sigma-2 Preferring Compounds: Implications In Cocaine-Induced Behaviors, Bahar Noorbakhsh Jan 2012

Pharmacological Characterization Of Sigma-2 Preferring Compounds: Implications In Cocaine-Induced Behaviors, Bahar Noorbakhsh

Graduate Theses, Dissertations, and Problem Reports (ETD)

Cocaine is a powerful psychostimulant that is highly abused by 1.9 million people in the United States. It accounts for more emergency department visits than any other illicit drug. Even with the high rate of cocaine abuse, no FDA approved pharmacological treatments exist. Many attempts at finding a pharmacotherapy for cocaine abuse and addiction have been made, but proven unsuccessful. Cocaine is known to bind sigma receptors at physiologically relevant concentrations, deeming them potential targets for cocaine pharmacotherapies and helping to elucidate the actions of cocaine. Two subtypes of sigma receptors have been described, sigma-1 and sigma-2. Minimal information is …


Synthesis Of Functional 1,2,3-Triazoles And Its Applications In Transition Metal Catalysis, Wuming Yan Jan 2012

Synthesis Of Functional 1,2,3-Triazoles And Its Applications In Transition Metal Catalysis, Wuming Yan

Graduate Theses, Dissertations, and Problem Reports (ETD)

Several new methodologies for synthesizing functional 1,2,3-triazoles which include arylation, vinylation, propargylation and allenation, have been successfully developed. These resulting new methods are of great benefit to the organic chemists who are working on the research fields related to 1,2,3-triazoles. Particularly, the iron catalyzed propargylation and allenation have initiated the iron chemistry with 1,2,3-triazoles as the ligand. For example, our efforts led to the discovery of a practical approach for the synthesis of conjugated enynes that is challenging through conventional methods. In the synthesis of conjugated enyne, 1,2,3-triazoles were revealed as the only ligand effectively promoting this important and challenging …


The Relationship Between Identity And Intimacy As Moderated By Culture, Garima Jhingon Jan 2012

The Relationship Between Identity And Intimacy As Moderated By Culture, Garima Jhingon

Electronic Theses and Dissertations

Several important developmental processes occur in the young adulthood period. Young adults form their identities, determine trajectories regarding careers, and typically they form intimate relationships. Erikson (1963) stated that healthy identity development during adolescence is a necessary precursor to intimacy in romantic relationships during emerging adulthood. Although findings from cross-sectional and short-term longitudinal studies somewhat confirm the proposed link between identity and intimacy development, none of them addresses the role of culture in moderating Erikson‘s tenets of developmental ordering. The primary goal of the present investigation was to determine the role of cultural orientation in identity and intimacy development among …


Understanding Phonological Memory Deficits In Boys With Attention-Deficit/Hyperactivity Disorder (Adhd): Dissociation Of Short-Term Storage And Articulatory Rehearsal Processes, Jennifer Bolden Jan 2012

Understanding Phonological Memory Deficits In Boys With Attention-Deficit/Hyperactivity Disorder (Adhd): Dissociation Of Short-Term Storage And Articulatory Rehearsal Processes, Jennifer Bolden

Electronic Theses and Dissertations

The current study dissociated and examined the two primary components of the phonological working memory subsystem – the short-term store and articulatory rehearsal mechanism – in boys with ADHD (n = 18) relative to typically developing boys (n = 15). Word lists of increasing length (2, 4, and 6 words per trial) were presented to and recalled by children following a brief (3 s) interval to assess their phonological short-term storage capacity. Children’s ability to utilize the articulatory rehearsal mechanism to actively maintain information in the phonological short-term store was assessed using word lists at their established memory span but …


Predictors Of Immunosuppressant Adherence In Long-Term Renal Transplant Recipients, Sandra J. Galura Jan 2012

Predictors Of Immunosuppressant Adherence In Long-Term Renal Transplant Recipients, Sandra J. Galura

Electronic Theses and Dissertations

To sustain the health and viability of renal transplants, adherence to immunosuppressant therapy (IST) medications is critical. Studies continue to identify decreased adherence rates as time from transplant increases (Chisholm-Burns, Kwong, Mulloy & Spivey, 2008; Chisholm, Lance, Mulloy, 2005; Chisholm, Mulloy, & DiPiro, 2005; Nivens & Thomas, 2009). While previous research has explored the effect of variables known to influence IST adherence in adult renal transplant recipients, limited studies have explored these variables in a population of renal transplant recipients with longer time posttransplant intervals. The purpose of this study was to examine demographic variables, time posttransplant, immunosuppressive agents, health …


The Dynamic Functions Of Bax Are Dependent On Key Structural And Regulatory Features, Rebecca Boohaker Jan 2012

The Dynamic Functions Of Bax Are Dependent On Key Structural And Regulatory Features, Rebecca Boohaker

Electronic Theses and Dissertations

Bax is an essential mediator of cell fate. Since its discovery in 1985 as a protein that interacts with the anti-apoptotic protein, Bcl-2, key elements related to its function, structure and regulation remains to be determined. To this end, mitochondrial metabolism was examined in non-apoptotic Bax-deficient HCT-116 cells as well as primary hepatocytes from Bax-deficient mice. Although mitochondrial density and mitochondrial DNA content was the same in Bax-containing and Bax -deficient cells, MitoTracker staining patterns differed, suggesting the existence of Bax -dependent functional differences in mitochondrial physiology. Oxygen consumption and cellular ATP levels were reduced in Bax -deficient cells, while …


Map1272c Encodes An Nlpc/P60 Protein, An Antigen Detected In Cattle With Johne’S Disease, John Bannantine, Cari K. Lingle, Judith R. Stabel, Kasra X. Ramyar, Brandon L. Garcia, Alex J. Raeber, Pascal Schacher, Vivek Kapur, Brian V. Geisbrechtb Jan 2012

Map1272c Encodes An Nlpc/P60 Protein, An Antigen Detected In Cattle With Johne’S Disease, John Bannantine, Cari K. Lingle, Judith R. Stabel, Kasra X. Ramyar, Brandon L. Garcia, Alex J. Raeber, Pascal Schacher, Vivek Kapur, Brian V. Geisbrechtb

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

The protein encoded by MAP1272c has been shown to be an antigen of Mycobacterium avium subsp. paratuberculosis that con- tains an NlpC/P60 superfamily domain found in lipoproteins or integral membrane proteins. Proteins containing this domain have diverse enzymatic functions that include peptidases, amidases, and acetyltransferases. The NlpC protein was examined in comparison to over 100 recombinant proteins and showed the strongest antigenicity when analyzed with sera from cattle with Johne’s disease. To further localize the immunogenicity of NlpC, recombinant proteins representing defined regions were ex- pressed and evaluated with sera from cattle with Johne’s disease. The region from amino acids …


Characterization Of Sorghum Grain And Evaluation Of Sorghum Flour In A Chinese Egg Noodle System, Liman Liu, Thomas J. Herald, Donghai Wang, Jeff D. Wilson, Scott R. Bean, Fadi M. Aramouni Jan 2012

Characterization Of Sorghum Grain And Evaluation Of Sorghum Flour In A Chinese Egg Noodle System, Liman Liu, Thomas J. Herald, Donghai Wang, Jeff D. Wilson, Scott R. Bean, Fadi M. Aramouni

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Sorghum is a gluten free grain that has potential to be used as an alternative to wheat flour for the Celiac Sprue market. There are thousands of sorghum lines that have not been characterized for grain, flour or end product quality. The objective of the research was to gain an understanding among grain sorghum quality factors and Chinese egg noodles quality. Four sorghum hybrids were characterized and evaluated for kernel characteristics, proximate analysis, flour composition and end product in a Chinese egg noodle system. Kernel size and weight affected the flour particle size and the amount of starch damage. Flour …


Post-Biological Control Invasion Trajectory For Melaleuca Quinquenervia In A Seasonally Inundated Wetland, Philip W. Tipping, Melissa R. Martin, Ryan Pierce, Ted D. Center, Paul R. Pratt, Min B. Rayamajhi Jan 2012

Post-Biological Control Invasion Trajectory For Melaleuca Quinquenervia In A Seasonally Inundated Wetland, Philip W. Tipping, Melissa R. Martin, Ryan Pierce, Ted D. Center, Paul R. Pratt, Min B. Rayamajhi

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

The recruitment and mortality of Melaleuca quinquenervia seedlings were evaluated over a 3-year period in a seasonally inundated wetland in the western Everglades region. The mean (±SE) density of seedlings/ saplingsm-1 declined from 64.8 (±4.5) to 0.5 (±0.2) over the 3 years, a population reduction of 99.2%. Four distinct water regimes characterized this site: dry, dry to wet transition, flooded, and wet to dry transition. Seedling recruitment was highest in the dry to wet transition and lowest in the flooded water regime, while mortality was highest under flooded and dry water regimes. The mean estimate of population growth (λ) …


Judging Parents, Judging Place: Poverty, Rurality, And Termination Of Parental Rights, Janet L. Wallace, Lisa R. Pruitt Jan 2012

Judging Parents, Judging Place: Poverty, Rurality, And Termination Of Parental Rights, Janet L. Wallace, Lisa R. Pruitt

Missouri Law Review

Parents are judged constantly, by fellow parents and by wider society. But the consequences of judging parents may extend beyond community reputation and social status. One of the harshest potential consequences is the state's termination of parental rights. In such legal contexts, the state assesses parents' merits as parents in relation to a wide array of their characteristics, decisions and actions, including where the parents live. Among those parents judged harshly in relation to geography are impoverished parents who live in rural places. We argue that such judgments are unjust because poor rural parents often do not have ready access …


Recovery Of Dna Profiles From Fingerprints On Paper After The Application Of Ninhydrin Or Dfo Given Certain Time Periods, Marco Colin Lovejoy Jan 2012

Recovery Of Dna Profiles From Fingerprints On Paper After The Application Of Ninhydrin Or Dfo Given Certain Time Periods, Marco Colin Lovejoy

Graduate Theses, Dissertations, and Problem Reports (ETD)

This study examined the recovery of DNA profiles from fingerprints on paper. This examination occurred in three phases: initial determination of DNA profiles on paper, recovery of DNA profiles given certain time periods, and recovery of DNA profiles after the application of the chemical enhancement techniques of ninhydrin or DFO given certain time periods. Phase II and Phase III paper sheets were exposed to the environment to simulate a house setting. All samples from the phases were extracted with phenol-chloroform. Samples from Phase I and Phase II were amplified with AMPF/STRRTM IdentifilerRTM amplification kit while samples from Phase III were …


The Role Of Src-Homology 2 Domain-Containing Tyrosine Phosphatase 2 In Signaling And Tumorigenesis Of Basal Type/Triple Negative Breast Cancer, Fatimah Kh. Matalkah Jan 2012

The Role Of Src-Homology 2 Domain-Containing Tyrosine Phosphatase 2 In Signaling And Tumorigenesis Of Basal Type/Triple Negative Breast Cancer, Fatimah Kh. Matalkah

Graduate Theses, Dissertations, and Problem Reports (ETD)

Basal type/triple negative breast cancer (BTBC) represents a distinct tumor group that is characterized by an aggressive disease phenotype and poor clinical outcome. Patients with this subtype cannot benefit from the available anti-hormone and anti-HER2 targeted therapies (e.g. tamoxifen and herceptin). Therefore, characterizing potential therapeutic targets is urgently needed. We reasoned that the Src-homology 2 domain-containing tyrosine phosphatase 2 (SHP2) could serve as a therapeutic target in BTBC, because of its critical regulation of epidermal growth factor receptor (EGFR) which is overexpressed in BTBC. Here, we demonstrated that SHP2 knockdown in BTBC cell lines suppressed cell proliferation, migration, and transformation. …


Ambient Geochemical And Isotopic Variations In Groundwaters Across An Area Of Accelerating Shale Gas Development, Michon L. Mulder Jan 2012

Ambient Geochemical And Isotopic Variations In Groundwaters Across An Area Of Accelerating Shale Gas Development, Michon L. Mulder

Graduate Theses, Dissertations, and Problem Reports (ETD)

One of the main challenges associated with Marcellus Formation shale gas development is to ensure proper management and disposal of flowback water produced as a result of hydraulic fracturing of gas wells. The flowback water consists of a mixture of returned frac'ing fluids and highly saline formation brines. As a result, improper management or disposal of this flowback can potentially contaminate the fresh surface waters and groundwaters of the area. To better assess any detrimental effect on water quality, there is need to understand the natural geochemical variations prior to the rapid expansion of gas drilling in the area.;This study …


Treatment Of Nightmares Using Imagery Rehearsal Therapy: A Multiple Baseline Study, Michael R. Nadorff Jan 2012

Treatment Of Nightmares Using Imagery Rehearsal Therapy: A Multiple Baseline Study, Michael R. Nadorff

Graduate Theses, Dissertations, and Problem Reports (ETD)

Nightmares have been linked with several negative consequences, including death by suicide. Further, nightmare sufferers report that nightmares have a significant negative impact on their lives. To address this problem, several nightmare treatments have been studied, with Imagery Rehearsal Therapy (IRT) having the greatest amount of empirical support. However, there are many unanswered questions in regard to IRT, such as how quickly one may see an effect and whether or not there is a temporary increase in nightmares prior to a decrease. The current study aimed to address these questions by examining IRT using a non-concurrent multiple baseline design. Four …


Detection And Characterization Of Pyromarkers Of Smoked Drugs Of Abuse, Rona Kiyomi Nishikawa Jan 2012

Detection And Characterization Of Pyromarkers Of Smoked Drugs Of Abuse, Rona Kiyomi Nishikawa

Graduate Theses, Dissertations, and Problem Reports (ETD)

Smoking or inhalation has increased in popularity as the choice route of administration of drugs of abuse amongst drug abusers. Combustion products associated with the smoking event (pyromarkers) of these smoked drugs of abuse can be useful in post mortem toxicological analysis both for investigative and public health applications. A method using analytical pyrolysis was developed to simulate the smoking process used for illicit drugs, which is significantly different than methods used for studies of conventional tobacco smoking, This method was used to identify possible markers associated smoked fentanyl and mixes of heroin and fentanyl. Thermocouple temperature probes were used …


“For Tomorrow Will Worry About Itself": Ivan Illich’S Deschooling Society And The Rediscovery Of Hope, Jared Gibbs Jan 2012

“For Tomorrow Will Worry About Itself": Ivan Illich’S Deschooling Society And The Rediscovery Of Hope, Jared Gibbs

Western New England Law Review

This Article examines Ivan Illich’s critique of American schooling and suggested educational reforms in his book, Deschooling Schooling. Illich's critique is based upon his position that American schools are manipulative institutions based on the law of rising expectations which creates a growing frustration gap. Manipulative institutions foster consumer dependence on an institution’s service. Illich suggests schools be reformed to become convivial, allowing for individual agency that permits an individual to freely act as one chooses. Illich refers to this suggested system as learning webs or opportunity webs. The Author identifies problems with instituting Illich’s learning webs. Illich proposed that private …


Exchange As A Cornerstone Of Families, Martha M. Ertman Jan 2012

Exchange As A Cornerstone Of Families, Martha M. Ertman

Western New England Law Review

In this Article, the Author examines Ivan Illich’s linkages between gender and industrial capitalism discussed in Illich’s book, Gender. First, the Article describes Illich’s allergy to exchange as the agent that replaced households defined by vernacular gender with married pairs in “inhumane” sex-neutral economic partnerships. Second, the Article challenges Illich’s view of exchange as a destroyer that has meddled in families for only a few hundred years. The Author uses sociobiological literature to counter Illich’s case against exchange with one valorizing two exchanges that she calls “primal deals” that played crucial roles in the evolution of humans, families, and day-to-day …


Symposium: Radical Nemesis: Re-Envisioning Ivan Illich’S Theories On Social Institutions: Foreword, Jennifer L. Levi Jan 2012

Symposium: Radical Nemesis: Re-Envisioning Ivan Illich’S Theories On Social Institutions: Foreword, Jennifer L. Levi

Western New England Law Review

The eight articles in this Symposium issue reflect the divergent topics that Ivan Illich managed to reflect upon in his life’s works. The topics include discussion of prisons, education, family law structures, privatization of welfare services and its impact on labor consciousness, media, and the rule of law. The pieces speak for themselves and need no elaboration here.


Land Use For Energy Conservation And Sustainable Development: A New Path Toward Climate Change Mitigation, John R. Nolon Jan 2012

Land Use For Energy Conservation And Sustainable Development: A New Path Toward Climate Change Mitigation, John R. Nolon

Elisabeth Haub School of Law Faculty Publications

Land use tools and techniques have impressive potential to reduce energy consumption, improve the economy, and mitigate climate change. This article explores the little understood influence of local land use decision-making on energy conservation and sustainable development and how it can mitigate climate change if properly assisted by the federal and state governments. The construction and use of buildings combined with extensive vehicular travel throughout the nation’s human settlements consume large amounts of energy, and much of that consumption is highly inefficient. By enforcing and enhancing energy codes, encouraging the use of combined heat and power and district energy systems, …


Arctic Justice: Addressing Persistent Organic Pollutants, Elizabeth Burleson Jan 2012

Arctic Justice: Addressing Persistent Organic Pollutants, Elizabeth Burleson

Elisabeth Haub School of Law Faculty Publications

This article recommends enhanced governance of persistent organic pollutants through incentives to develop environmentally sound, climate friendly technologies as well as caution in developing the Arctic. It highlights the toxicity challenges presented by POPs to Arctic people and ecosystems.


Reflections On Oceans And Sids, Ann Powers Jan 2012

Reflections On Oceans And Sids, Ann Powers

Elisabeth Haub School of Law Faculty Publications

A great deal has already been written about the UN Conference on Sustainable Development and its outcome document, “The Future We Want”. Much of the commentary has been critical of both the process and the document. To understand the process and the final result, it may be useful to look at how one or two issues advanced over the course of the negotiations. Both ocean advocates and representatives of Small Island Developing States (SIDS) seemed relatively satisfied with the results of the conference, and a look at those interlinked matters is interesting.


Reliable Science: Overcoming Public Doubts In The Climate Change Debate, Michelle S. Simon Jan 2012

Reliable Science: Overcoming Public Doubts In The Climate Change Debate, Michelle S. Simon

Elisabeth Haub School of Law Faculty Publications

This article will consider the case for instituting a domestic agency that would evaluate the findings from Intergovernmental Panel on Climate Change (IPCC) assessments to improve the credibility and legitimacy of those claims and conclusions for multiple purposes. The proposed agency would consider the robustness of an assessment's conclusions by construing the evidence through the lens of Daubert rather than Frye. Part I will outline the public debate about climate science-what the debate is about and why it exists. Part II will examine the current role of the IPCC-what it is and why it has not been successful in legitimating …


Climate Change And Cercla Remedies: Adaptation Strategies For Contaminated Sediment Sites, Katrina Fischer Kuh Jan 2012

Climate Change And Cercla Remedies: Adaptation Strategies For Contaminated Sediment Sites, Katrina Fischer Kuh

Elisabeth Haub School of Law Faculty Publications

This article considers climate change questions in the context of a particular type of contaminated site--sites with contaminated sediments subject to the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA). Although climate change may impact a variety of waste sites in different ways, even those without sediment contamination, this article focuses on sediment sites so as to frame a more manageable inquiry susceptible to in-depth treatment. The following section, Part II, identifies the vulnerability of contaminated sediment sites to climate change. The section describes sediment contamination, regulatory approaches to remediating contaminated sediments, and how climate change may impact sediment remedies. …