Digital Commons Network^™

High-Throughput Screens Identify Genotype-Specific Therapeutics For Channelopathies, Christian L. Egly, Alex Shen, Tri Q. Do, Carlos Tellet Cabiya, Paxton A. Ritschel, Suah Woo, Matthew Ku, Brian P. Delisle, Brett M. Kroncke, Björn C. Knollmann

Physiology Faculty Publications

Genetic diseases such as ion channelopathies substantially burden human health. Existing treatments are limited and not genotype specific. Here, we report a 2-step high-throughput approach to rapidly identify drug candidates for repurposing as genotype-specific therapy. We first screened 1,680 medicines using a thallium-flux trafficking assay against Kv11.1 gene variants causing long QT syndrome (LQTS), an ion channelopathy associated with fatal cardiac arrhythmia. We identified evacetrapib as a suitable drug candidate that improves membrane trafficking and activates channels. We then used deep mutational scanning to prospectively identify all Kv11.1 missense variants in an LQTS hotspot region responsive to treatment with evacetrapib. …

The Global Hypophosphatasia Registry: Lessons Learned From A Decade Of Real-World Data., Priya S. Kishnani, Lothar Seefried, Keiichi Ozono, Gabriel Ángel Martos-Moreno, Cheryl Rockman-Greenberg, Deborah Fowler, Luke K. Burke, William R. Mowrey, Eric T. Rush, Peter R. Ebeling, Wolfgang Högler, Agnès Linglart, Shona Fang, Anna Petryk, Kathryn M. Dahir

Manuscripts, Articles, Book Chapters and Other Papers

INTRODUCTION: Hypophosphatasia (HPP) is an inherited, metabolic, rare disease characterized by a high level of clinical heterogeneity. In response to this robust heterogeneity, the Global HPP Registry was formed to characterize the types of manifestations that patients may experience, as well as to compile information on genetic underpinnings of the disease, overall impact on patient quality of life, and safety and effectiveness of enzyme replacement therapy. The objective of this review was to synthesize key learnings gained from the Global HPP Registry, which is now in its tenth year of enrolling patients.

METHODS: Registry data were analyzed to provide up-to-date …

Candida Glabrata Vertebral Osteomyelitis Following L3-4 Transforaminal Lumbar Fusion: Illustrative Case, Bryce R. Michael, Adam Youssef, Paige Grafton, Saleh Mostafa, Jonathan Sayegh, Luis A. Robles, Abduljabbar Alhammoud

Student Publications

Background: Candida vertebral osteomyelitis is rare, particularly following instrumented spine surgery. Candida glabrata presents additional management challenges due to its frequent resistance to azole antifungal treatment and its association with immunocompromised hosts.

Observations: A 74-year-old immunosuppressed man underwent L3-4 transforaminal lumbar interbody fusion with cyst excision. Seven weeks postoperatively, he presented with constitutional symptoms and elevated inflammatory markers but was discharged with presumed viral illness. Nine months after surgery, imaging revealed cage displacement. Intraoperative cultures during hardware removal identified C. glabrata. The patient underwent repeat irrigation and debridement with hardware exchange and was treated with intravenous micafungin and oral fluconazole …

Critical Technology Areas Part 2: Implications And Recommendations For The Warfighter And Warfighting, James Giordano

Strategic Insights

This commentary builds on the designation of six Critical Technology Areas defined by the U.S. Department of War: Applied Artificial Intelligence, biomanufacturing, contested logistics technologies, quantum and battlefield information dominance, scaled directed energy, and scaled hypersonics, to analyze their implications for future warfighting and to offer practical recommendations. Dr. Giordano explains how these technologies will compress decision timelines, blur attribution, and integrate across domains, fundamentally altering operational tempo and strategic risk. Preparing warfighters for these changes requires heightened technical literacy, updated education and training, organizational adaptation, and robust ethical frameworks. The article argues that doctrinal evolution, iterative experimentation, and interdisciplinary …

Chimes: November 24, 2025, Calvin University

Chimes

Student Senate welcomes LCS council by Ellery Johnson

Administrators respond to student questions in second academic transition town hall by Ian Tjoelker & Ashley Hammons

Matins: A poetry collection by Professor Otto Selles by McKenna Wilkinson

No Noise November: A spiritual, physical and mental practice by Ella Vanden Berg

Seminary: A "seedbed" for growth by Joe Toly

Calvin's Women's Rugby on the rise by Hendrik Beelen

Furry friends on campus keep watch over students by Ashley Hamons & Maya Oeverman

"You Will Be Like God": On freedom and the fall of Anakin Skywalker by Joe Toly

Node-Attributed Spatial Graph Partitioning: A Kullback-Leibler Divergence Based Approach, Valentin Nechita

Electronic Theses and Dissertations

This thesis presents a novel approach to node-attributed spatial graph partitioning (NSGP) that addresses limitations in existing homogeneity measures. We introduce a Kullback-Leibler (KL) divergence-based formulation we name KLD that measures attribute similarity by comparing each node’s distribution to its subgraph centroid, providing a computationally efficient method of measuring homogeneity. Integrated within a multilevel graph partitioning framework and Fiduccia-Mattheyses refinement, our approach achieves approximately 90% runtime reduction compared to the baseline Clustering and Local Refinement (CLR) algorithm while maintaining comparable partition quality. Applied to COVID-19 infection data combined with American Community Survey demographics across U.S. FIPS codes, KLD successfully identifies …

Sampling Gear Performance And Elasmobranch Distributions In The Upper Florida Keys, Ethan L. Dewald

Electronic Theses and Dissertations

Elasmobranchs (sharks, skates, and rays) are vital marine predators, yet many populations are declining from overfishing and habitat loss. Marine protected areas like the Florida Keys National Marine Sanctuary (FKNMS) can support recovery, but knowledge gaps remain in habitat-specific community structure and survey effectiveness. I surveyed inshore (seagrass, hardbottom) and offshore (patch reef, bank reef) habitats in the Upper Florida Keys using longlines, drumlines, baited remote underwater video (BRUVs), and unmanned aerial vehicles (UAVs). Inshore assemblages showed strong habitat-driven patterns, with Ginglymostoma cirratum dominating seagrass sites, whereas offshore reefs were more homogeneous. UAVs captured the highest inshore richness, and drumlines …

A Contemporary Review On Heart Failure With Improved Ejection Fraction, Allison Weiss, Ambre Flowers, Scott D Eisenberg, Lingling Wu, Mario Rodriguez, Muzamil Khawaja, Errol Moras, Carl J Lavie, Gregg C Fonarow, W H Wilson Tang, Biykem Bozkurt, Chayakrit Krittanawong

Faculty, Staff and Students Publications

Heart failure is a complex condition caused by various etiologies that reduce cardiac output or increase cardiac pressures. It is classified by left ventricular ejection fraction, a key prognostic factor. New therapies, devices, and better management of secondary causes have improved outcomes. A recently identified group-those with heart failure and improved ejection fraction-shows better prognosis. This review explores its definition, causes, clinical significance, and management strategies.

Stiefel Md Anderson Oropharynx Cancer (Mda-Opc) Cohort: A Single-Institution, Prospective Longitudinal Outcomes Study, Amy Moreno, Ariana J Sahli, Faye Johnson, Xiaowen Sun, Carly Barbon, Waree Rinsurongkawong, Wenye Song, Flavie M Luciani, Han Liang, Jun Li, Wei Liu, J Jack Lee, S J Frank, Stephen Lai, Clifton Fuller, Katherine Hutcheson

Faculty, Staff and Student Publications

Purpose: The MD Anderson Oropharynx Cancer (MDA-OPC) cohort is a unique single-institution, prospective longitudinal cancer cohort. The cohort aims to enhance the therapeutic index of OPC management by supporting data needs for independent investigators to conduct rigorous observational studies examining exposures and factors associated with acute and late toxicities, cancer progression, recurrence, new malignancies and quality of life in OPC survivors.

Participants: A total of 1811 patients with OPC with a minimum follow-up of 6 months have been consented to our prospective registry between 18 March 2015 and 29 December 2023. Clinical and treatment (Tx) data are available on all …

Mycobacterium Chelonae Outbreak Investigation At A Quaternary Pediatric Hospital Following The Opening Of A Leed-Certified Critical Care Tower: Where Does Water Sustainability Intersect With Infection Control?, Andrea L Ankrum, Silvia M Caceres, Michael Torsell, Elaine Epperson, Vinicius Calado Nogueira De Moura, Jennifer J Gilick, Michael Strong, Qingyun Liu, Matthew J Strand, Rachel N Wilsey, Jennifer R Honda, Jane E Gross, Felicia A Scaggs-Huang

Faculty, Staff and Student Publications

Objective: Investigate the increased incidence of Mycobacterium chelonae positive respiratory cultures in hospitalized patients.

Design: Apply the Healthcare-Associated Links in Transmission of Nontuberculous Mycobacteria (HALT NTM) toolkit to an outbreak investigation of M. chelonae.

Setting: Quaternary-care pediatric hospital and medical center in the United States with a recently opened LEED-certified critical care tower.

Patients: Adult and pediatric patients with M. chelonae positive respiratory cultures between June 2022 and January 2024.

Methods: An epidemiological investigation involving clinical and laboratory practices, water management, building construction and renovation projects. Environmental sampling of air vents, water sources and endoscope reprocessing equipment was performed. M. …

Analysis Of A Deeply-Phenotyped Familial Hypercholesterolemia Cohort From Mexico Shows A Role For Both Rare And Common Alleles Across Known Dyslipidemia Genes And Reveals Structural Variation In A Novel Locus, Nicholas Katsanis, Niki Mourtzi, Consuelo D Quinto-Cortés, Alexandro J Martagon, Alexander G Ioannidis, Francisco M De La Vega, Jeff Gulcher, Ming Ta Michael Lee, Mohammad A Faghihi, Arturo Lopez-Pineda, Sonia Moreno-Grau, Daniel Mas Montserrat, Míriam Barrabés, David Bonet, Pavel Salazar Fernandez, Jeff Wall, Babak Moatamed, Roopa Mehta, Gabriela A Galan-Ramirez, Rafael Zubirán, Daniel Elias-Lopez, Teresa Tusié-Luna, Carlos A Aguilar-Salinas, Carlos D Bustamante

Faculty, Staff and Student Publications

Familial hypercholesterolemia (FH) is a genetic disorder driven in part by mutations in three genes that encode components of the cholesterol pathway: LDLR, APOB, and PCSK9. However, the majority of FH genetics has been performed in individuals of European descent. Here, we leveraged a cohort of 300 patients from the Mexican FH registry to understand how rare, high liability alleles and common variants might contribute to shaping individual risk. Using a combination of whole exome and of short- and long-read whole genome sequencing, we report three key findings. First, we observed that rare pathogenic point mutations and structural variants in …

Population Dynamics, Host Range, And Impact Of The Naturalized Weevil Ochyromera Ligustri: A Potential Biological Control Agent Of Invasive Ligustrum Sinense, Brandi H. Misiaszek

LSU Master's Theses

Invasive woody plants have become dominant components of many forest understories in the southeastern United States. These species can displace native species, disrupt ecosystem processes, and reduce biodiversity. Chinese privet (Oleaceae: Ligustrum sinense Lour.) is an invasive shrub distributed through the Southeastern United States. The ligustrum weevil (Coleoptera: Curculionidae: Ochyromera ligustri Warner) is a non-native insect that was first found in the U.S. on Ligustrum in 1959. This weevil is considered a potential fortuitous biological control agent of invasive Ligustrum spp. in the U.S. The objectives of this study were to evaluate O. ligustri as a potential biological control agent …

Modified Artificial Neural Networks In Stochastic Differential Equations To Estimate The Occurrence Rate Of A New Process For Software Reliability Growth Modelling, Adel Sufyan Hussain, Zedan Zubair Mashikhin, Noora Taha Abduirazzaq

Baghdad Science Journal

This paper aims to utilize modified artificial neural networks under stochastic differential equations to improve the estimation of occurrence rates on models towards the growth of software reliability through such models. There has never been a time when reliable assessment methods have been more important as software systems grow ever more sophisticated. This study covers the risks arising from software bugs, security weaknesses, and the need to meet legal requirements. The authors use a new method that combines artificial intelligence techniques with classical reliability models to achieve their goal of a more efficient computational tool for predicting software reliability. It …

Serum Levels Of Uchl1 And S100b In Covid-19 And Multiple Sclerosis Patients: A Comparative Study In Erbil City, Krg, Iraq, Daldar Fares Jeejo, Mayada Noori Iqbal, Nisreen Sherif Alyasiri

Baghdad Science Journal

Ubiquitin carboxyl-terminal hydrolase L1 (UCHL1) and S100B are proteins involved in neuronal development and damage. Their levels in serum have been proposed as potential biomarkers for various neurological conditions, including COVID-19 and Multiple Sclerosis (MS). The study aimed to compare serum levels of UCHL1 and S100B among COVID-19 patients, MS patients, and healthy controls, and to assess the correlation between these biomarkers in the context of COVID-19. This cross-sectional study included 91 COVID-19 patients, 29 MS patients, and 50 healthy controls from the Kurdistan Region (KRG) of Iraq. Serum levels of UCHL1 and S100B were quantified using enzyme-linked immunosorbent assay …

Efficient Face Mask Recognition Model Based On Deep Learning And Multi-Machine Learning Classifiers, Hassenien Ali Hussein, Firas Muneam Bachay, Saffa Jasim Mosa, Mohammed Hasan Abdulameer

Baghdad Science Journal

Safety in chemical and biological laboratories requires face masks. Nevertheless, the masked face images present obstacles to accommodate the wide pose variations, low resolution, changes in size and incomplete cropping, and varying emotive expressions, making feature extraction and recognition robust difficult. To decern between faces with proper, improper, and no facemask, Deep Learning (the use of Convolutional Neural Networks (CNNs)) and classifiers such as SoftMax, Support Vector Machines (SVM) and K-Nearest Neighbors (KNN) were used. The methodology utilized the 2075 AR face images that contain various resolutions, orientations, and occlusions. The paper develops a Deep Learning-based model utilizing CNNs and …

Thinning Antarctic Glaciers Expose High-Altitude Nunataks Delivering More Bioavailable Iron To The Southern Ocean, Kate Winter, John Woodward, Stuart A. Dunning, James R. Jordan, Joseph A. Graly, Matthew J. Westoby, Sian F. Henley, Robert Raiswell

School of Geography, Earth and Environmental Sciences

Glacial systems entrain and transfer sediment, rich in essential nutrients, from continental sources to the ocean, where they are released by meltwater. In the Southern Ocean, primary producers are limited by the availability of micronutrients, like iron (Fe), so any increase in continental sediment supply could enhance primary productivity and subsequent drawdown of atmospheric CO₂. Here we provide a systematic account of labile Fe concentrations in Antarctic continental sediments. Ferrihydrite and crystalline Fe (oxyhydr)oxides were extracted from 27 Antarctic samples collected from nunataks, lateral moraines and blue ice areas in the Sør Rondane Mountains, East Antarctica. We report …

Investigating The Mechanisms Of Microbial Interactions Using A Model Cystic Fibrosis Polymicrobial Community, Bassam El Hafi

Dartmouth College Ph.D Dissertations

Cystic fibrosis (CF) airway microbial communities are complex ecosystems where interspecies interactions influence pathogen survival and disease progression. We leverage a CF-relevant in vitro four-species model composed of Pseudomonas aeruginosa, Staphylococcus aureus, Streptococcus sanguinis, and Prevotella melaninogenica, alongside a microbiome dataset with over 4,000 respiratory samples from publicly available sequencing data of CF patient samples, to explore the dynamics of microbial interactions in CF. On a broader scale, we performed microbial network analysis to examine how the latest modulator therapy, elexacaftor/tezacaftor/ivacaftor (ETI), might influence CF microbial communities. Our analysis revealed a reduction in node connections and …

Revisiting The Meaning Of 'Forests'—In Re: T.N. Godavarman Thirumulpad V Uoi, Gayathri D. Naik

Journal of Law and Public Policy

This Case Comment reflects on the contributions of the judiciary to forest governance and management through the use of continuous mandamus in the landmark case T.N. Godavarman v UoI. It offers insights into these contributions, particularly an expansion of the understanding of ‘forests’, by examining the latest judicial decision in the Godavarman series, which was on the protection of sacred groves in Rajasthan. The expansion of the definition of ‘forests’ to include sacred groves can help accord the protection and ensure the preservation of these small forest lands with rich biodiversity and religious and cultural significance.

Exploring The Recognition Of Internalizing Problems Among Black Students: Delving Into The Youth Mental Health Help-Seeking Pathway, Marketta A. Adams

LSU Master's Theses

The mental health of Black adolescents is a growing concern, with high prevalence rates of internalizing disorders such as anxiety and depression. National studies report that nearly 47% of Black adolescents experience a mental health disorder by age 18, with over 60% reporting moderate to severe depressive symptomology. Despite these alarming rates, Black youth underutilize mental health services, often due to cultural stigma, limited access to culturally competent care, and under-recognition of their mental health needs. This study aimed to explore problem recognition as a key component in the mental health help-seeking pathway for Black adolescents in school settings. Grounded …

“What Are We And What’S Coming Next?”: Queer People’S Experiences During Sociopolitical Unrest In The Us, Ariana Cristal Morales

Master's Theses

Queer (lesbian, gay, bisexual, transgender, queer, or other gender and sexual identities) folx have become a major focal point during political elections. As political climates have projected forced attacks towards queer populations, society has followed suit. Investigation on the impacts of such changes towards queer folx is important to uncover, as sociopolitical climates have shifted within the last 10 years in the US. The present study utilizes a phenomenological framework to understand the lived experiences of queer participants living in the US from 2015-2025 during political and social shifts. Semi-structured interviews were utilized to explore 10 queer participant’s lived experience …

Analysis Of The Submergence, Landing, And Navigation Of An Autonomous Underwater Landing Vehicle, Theresa Wainwright

Electronic Theses and Dissertations

Autonomous Underwater Landing Vehicles allow for seafloor data to be taken in multiple locations with little to no human intervention. The movement of these vehicles needs to be analyzed through simulated to ensure the correct programming of vehicle missions. This analysis includes the surface navigation, the drift experienced by the vehicle during descent, and the seafloor stability of the vehicle. The results then inform the limitations of this vehicle and the necessary adjustments to subsequent versions. Surface navigation allows understanding of vehicle movement between ascent locations, waypoints, and descent locations. Drift during descent allows for visual of the vehicle’s movements …

Sustained Cellular Survival Amid Amyloid Beta (Aβ) Burden, Giselle Shim

Electronic Theses and Dissertations

Amyloid beta (Aβ) accumulation is a hallmark of Alzheimer’s disease (AD), persisting in the brain for years. Despite its neurotoxic potential, widespread neuronal death is not consistently observed. Histopathological analysis indicates that most neurons remain viable, suggesting an altered survival state under chronic Aβ burden. This study integrates clinical, imaging, and in vitro evidence to characterize this non-lethal state. FDG-PET imaging reveals reduced glucose metabolism. In vitro, Aβ exposure leads to decreased uptake of glucose and amino acids. Reductions in ATP levels and AMPK activity indicate impaired metabolic regulation. Despite these metabolic disruptions, cell death is not observed, implying a …

The Influence Of Russian Folklore On Perceptions Of Female Heroism, Mariia V. Subbotina

Heroism Science

This article examines how Russian folklore traditions have shaped cultural perceptions of female heroism. The study addresses the limited attention given to gendered aspects of heroism, particularly “female” models, which are often linked to self-sacrifice and resilience, in contrast to “male” heroism associated with physical strength and risk. As the first stage of a larger project, this research aims to introduce the issue and identify key archetypes of female heroism. Based on an analysis of A.N. Afanasyev’s collection of fairy tales, three central archetypes of active heroines are identified: the Warrior Woman (Marya Morevna), the Wise Maiden/Enchantress (Vasilisa the Beautiful), …

2025 - The Sixth Annual Fall Symposium Of Student Scholars

Symposium of Student Scholars Program Books

The full program book from the Fall 2025 Symposium of Student Scholars, held in November 2025. Includes abstracts from the presentations and posters.

Fish-Spec: Fast Identification System For Handheld Spectroscopy And Species Classification, Mitchell Sueker, Nicholas Mackinnon, Gregory Bearman, Amanda Tabb, Diane Kim, Rosalee S. Hellberg, Alireza Akhbardeh, Hamid Reza Marateb, Jianwei Qin, Moon Kim, Fartash Vasefi, Hossein Kashani Zadeh

Food Science Faculty Articles and Research

Accurate fish species identification is critical to prevent mislabeling and fraud in the seafood industry. We present a handheld multi-mode point spectroscopy system that combines fluorescence (365 and 395 nm excitation) and reflectance measurements in the visible to near-infrared (∼350–900 nm) and short-wave infrared (∼900–1700 nm) regions for rapid, non-destructive classification of fish fillets. Tissue spectra were acquired at 25 positions on 68 fillets from 11 species, in both frozen and thawed states. Feature-level fusion across all four modes enabled higher classification accuracy than any single mode alone. A global machine-learning model classified all species with 85 ± 2.8 %, …

The Differential Effects Of Camp Mobilizing Agents On Tgf-Β-Induced Extracellular Matrix In Human Lung-Derived Fibroblasts: Insights Into Therapeutic Targets For Lung Fibrosis, Sarah Orfanos, Brian T. Deeney, Gaoyuan Cao, Nikhil Karmacharya, Anjani Ravi, Cynthia J. Koziol-White, Qi Yang, Rennolds S. Ostrom, Reynold A. Panettieri Jr.

Pharmacy Faculty Articles and Research

Background

Injury-repair responses typically induce tissue or organ scarring. Generally, cAMP-mobilizing agents inhibit the activation of fibroblasts and deposition of extracellular matrix. Some but not all cAMP-mobilizing agents inhibit fibrosis. Evidence suggests that inhaled treprostinil, a prostacyclin (IP) analog, increases intracellular cAMP levels [cAMP]I, and slows the decline in pulmonary function in patients with idiopathic pulmonary fibrosis (IPF). However, the molecular mechanisms by which cAMP-mobilizing agents, including treprostinil, alter the expression of matrix proteins in human lung fibroblasts (HLF) remain unclear. Unlike other Gαs -coupled receptors, we posit that the antifibrotic properties of treprostinil are driven by cAMP-mobilizing-dependent and -independent …

Gboost-Ctl: A Novel Method In Multi-Tissue Transcriptome-Wide Associations Studies In Cross-Tissue Learner Incorporating Gwas Information, Md Mutasim Billah, Hairong Wei, Fengzhu Sun, Kui Zhang

Michigan Tech Publications

Genome-wide association studies (GWAS) have uncovered numerous genetic variants linked to complex human diseases, yet linking these variants to transcripts and tissues that drive pathology remains difficult. Multi-tissue transcriptome-wide association studies (TWAS) offer a powerful bridge, but existing analytical methods have some limitations, either by discarding important signals by separately analyzing and then aggregating results across tissues, implying imputation models in individual tissues, or fusing them with weights that ignore how much GWAS signal each tissue actually carries. Therefore, most of the existing methods do not work uniformly across different GWAS cohorts. Here, we propose GBoost-CTL - a GWAS-boosted cross-tissue …

An Essay On Trailblazing With Service Animals Langer, Pilot, Bowie, And Izzie: Preserving Non-Partisan Public Health And The Law, Gary C. Norman

Journal of Law and Health

A direct correlation exists among humans, their animals, and human health and wellness. This article will focus concisely on law students with disabilities and lawyers with disabilities and how they can be empowered to be trailblazers while remaining healthy and well. Salutogenic Model should be optimized by lawyers with disabilities working at the intersection of animal law, disability law, and public health law. Service animals have positive and salubrious impacts upon their handlers in several ways, including psychosocial health and wellbeing. The Grand Architect (or in my Cherokee tradition, "great spirit") continuously partners me with complicated but magnificent dog partners …

Madagascar's Urban Lemur Meat Trade, Cortni Borgerson, Be Noel Razafindrapaoly, Be Jean Rodolph Rasolofoniaina

Department of Anthropology Faculty Scholarship and Creative Works

As the world's most endangered mammals, lemurs are key to understanding how humans and wildlife can sustainably coexist. We present the first national assessment of the urban lemur meat trade. We interviewed 2600 participants across 17 cities to determine its scale, target species, distribution, and drivers. We reveal a considerable trade, with thousands of threatened lemurs sold annually. This trade is largely hidden, with 95% of sales occurring directly between suppliers and a trusted clientele, and targets some of the nation's most endangered species, often during critical breeding seasons. While entrepreneurial peri-urban suppliers are lured by a dependable economic opportunity, …

Harnessing Hyperspectral Imaging And Deep Learning For Terrestrial Habitat Mapping In Arid Landscapes: A Case Study In Saudi Arabia, Ali Elgendy, Hesham Morgan, Brandon Tran, Rejoice Thomas, Tamer Ismail, Yehya Kh. Shehadeh, Ahmed Elgharib, Ahmed Abdullah Al-Dughairi, Ali El Muburak, Khaled Allam Harhash, Hesham El-Askary

Mathematics, Physics, and Computer Science Faculty Articles and Research

Arid ecosystems remain under-mapped at actionable scales despite their ecological importance. Decision makers lack reliable, high-resolution habitat maps in drylands to prioritize protection and target restoration. This research integrates spaceborne hyperspectral imaging from the Environmental Mapping and Analysis Program (EnMAP) with deep learning semantic segmentation models to produce an updated level of habitat classification based on the International Union for Conservation of Nature (IUCN) for part of the Imam Turki bin Abdullah Royal Reserve, Saudi Arabia. Using ground control points and the full EnMAP spectral cube without band selection, U-Net and DeepLabV3+ architectures were each implemented with VGG19 and ResNet-101 …