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Admissions Brochure 2012-2013, William & Mary Law School

Admissions Brochures

No abstract provided.

Black Women’S Perceptions Of The Relationship Among Nepotism, Cronyism Job Satisfaction, And Job-Focused Self-Efficacy, Johnson Lavoria Chandler

Doctoral Dissertations

Corporate America struggles with inclusion of certain groups such as Black women. Although Black women have met or surpassed their Caucasian, Hispanic, Asian, and Native American female counterparts and their Black male counterparts in education, and sit on boards of Fortune 500 companies, too many Black women are stymied in attempts for advancement as a result of nepotism and cronyism. Oftentimes, Black women are left with feelings of incompetence and believing they are undervalued in the workplace.

This study examined Black women's perceptions of nepotism and cronyism in the workplace. Further, the study was conducted to establish to what extent …

Hepatic Effect Of Inhaled Ozone In Sprague-Dawley Rat, Whitney Slone Theis

All ETDs from UAB

Ozone (O3) is a primary component of photochemical smog and represents a serious public health concern as more than 50% of the U.S. population lives in areas exceeding national ambient air quality standards for this toxic pollutant. Recent findings indicate that the effects of inhaled O3 extend to extra-pulmonary tissues like the heart and liver. We hypothesize that inhaled O3 exposure-related events in the lung will cause downstream alterations in the liver proteome. To test this, we exposed male Sprague-Dawley rats to 0.5 ppm ozone for 8 hr a day for 5 days. After exposures, livers were removed and proteomic …

Hepatic Effect Of Inhaled Ozone In Sprague-Dawley Rat, Whitney Slone Theis

All ETDs from UAB

Ozone (O3) is a primary component of photochemical smog and represents a serious public health concern as more than 50% of the U.S. population lives in areas exceeding national ambient air quality standards for this toxic pollutant. Recent findings indicate that the effects of inhaled O3 extend to extra-pulmonary tissues like the heart and liver. We hypothesize that inhaled O3 exposure-related events in the lung will cause downstream alterations in the liver proteome. To test this, we exposed male Sprague-Dawley rats to 0.5 ppm ozone for 8 hr a day for 5 days. After exposures, livers were removed and proteomic …

Environmental Enrichment Recouples Histone Methylation In The Hippocampus To Restore Cognition In Aging, Sarah Jean Morse

All ETDs from UAB

It is hypothesized that age-related memory deficits arise in part due to altered gene transcription within the hippocampus. These aberrations in gene transcription can lead to alterations in the induction of synaptic plasticity and subsequently interrupt the process of memory formation. Histone methylation-mediated chromatin remodeling mechanisms have recently emerged as crucial regulators of gene transcription in the hippocampus during memory formation. In the present study, we examined the contributions of histone methylation to cognitive deficits and transcriptional aberrations in the hippocampus throughout aging. We found that aging is associated with reduced histone acetylation and an increase in tri-methylation of histone …

Down-Modulation Of Mica On Malignant Glioma Cells By Herpes Simplex Virus, Carl Irwin Odom

All ETDs from UAB

Glioblastoma Multiforme is a primary malignancy of the central nervous system and is fatal for patients despite surgical resection and radiotherapy. Oncolytic Herpes Simplex Virus (oHSV) vectors deleted of the γ134.5 neurovirulence gene are potential therapies for treating glioblastoma tumors. Although replication in permissive cells is considered the primary mechanism of oHSV mediated tumor clearance, there is evidence that the immune system is part of the tumor clearance mechanism during treatment with oncolytic viruses. Specifically, natural killer (NK) cells may be important for tumor clearance during oHSV therapy. NK cell activation relies partially on the stimulation of activating or inhibitory …

Structural Investigations Of Retinoid X Receptor Transcriptional Activation By Anti-Cancer Rexinoids, Leeann J. Boerma

All ETDs from UAB

Nuclear receptor (NR) protein retinoid X receptor (RXR) is a ligand-inducible transcription factor that binds retinoids for regulation of target genes. Agonist binding induces a major structural rearrangement in the ligand binding domain (LBD) and formation of the coactivator binding interface. RXR-signaling pathways control proliferation, differentiation, and growth in epithelial tissues. To understand how RXR agonists enhance signaling at the molecular level requires an understanding of how agonists induce structural and dynamical changes in the LBD to recruit coactivators for activation of anti-cancer relevant transcription. While most studies of NR activation center on the position of Helix 12 (H12)/activation function-2 …

Kean University Institutional Profile 2012, Kean University

Evidence Inventory

No abstract provided.

Complex Interactions Between Marine Sponges And Their Symbiotic Microbial Communities, Christopher John Freeman

All ETDs from UAB

Microbial communities spanning nearly all evolutionary lineages of bacteria and archaea are found within many species of marine sponges. Although diverse microbial metabolic pathways may benefit sponge hosts, minimal experimental evidence exists supporting host assimilation of symbiont-derived nutrients. By coupling manipulative shading experiments with stable isotope analyses of isolated microbial and sponge cell fractions, I provide evidence that some sponge hosts assimilate a large proportion of their C and N from microbial symbionts and that these inputs are crucial to host performance. Interestingly, however, these interactions are highly variable across host species, suggesting that overall symbiont abundance alone does not …

Investigating Potential Novel Angiogenic And Immunogenic Properties Of Heme Oxygenase-1, Carl Antonio Frizell

All ETDs from UAB

INVESTIGATING POTENTIAL NOVEL ANGIOGENIC AND IMMUNOGENIC PROPERTIES OF HEME OXYGENASE-1 According to the American Heart Association and Centers of Disease Control and Prevention, cardiovascular diseases comprise the primary causes of death in the United States. Heme oxygenase-1 (HO-1), an inducible microsomal enzyme, catalyzes the rate limiting step in heme degradation releasing equimolar amounts of biliverdin, iron and carbon monoxide. Importantly, the induction of HO-1 is an adaptive response that affords protection in these disease states and several others. Expression of HO-1 has been demonstrated in several disease states and pathophysiological processes, including ischemia-reperfusion, inflammation and organ transplantation. This protection is …

Myosin Ii Regulates Actin Dynamics Critical For Structural Plasticity And Fear Memory Formation, Cristin Gavin

All ETDs from UAB

Dynamic changes to the actin cytoskeleton are required for synaptic plasticity and long-term memory formation. However, the molecular mechanisms that mediate filamentous actin (F-actin) dynamics during both activity-dependent synaptic potentiation and long-term memory encoding are poorly understood. Myosin II motor proteins are highly expressed in actin-rich growth structures in neurons, including dendritic spines. Recent work demonstrates that these molecular machines mobilize F-actin in response to synaptic stimulation and are required for memory encoding in CA1 hippocampus of rodents. The aims of this project were two-fold. First, we sought to establish if myosin II regulates actin filament polymerization necessary for structural …

Childhood Obesity: The Role Of Genetic Admixture, Parental Feeding Practices, And The School Food Environment, Michelle Cardel

All ETDs from UAB

Disentangling the etiology of pediatric obesity continues to challenge researchers due to the interconnecting of behavioral, physiological, environmental, and genetic factors. Studies have focused on the role of the obesogenic environment, characterized by excess energy intake and sedentary behavior, as it relates to weight and fat gain in children. Although these factors certainly have an impact on fat accumulation, increased energy intake and decreased physical activity do not solely account for the increasing trends in obesity prevalence. Less explored genetic and environmental factors may contribute independently and/or synergistically to the current obesity epidemic, and that, these factors could vary in …

Calcium Signaling And The Regulation Of Ecdysteroid Hormone Synthesis By Blue Crab (Callinectes Sapidus) Molting Glands, Hsiang-Yin Chen

All ETDs from UAB

In crustaceans, cellular events that lead to molting are triggered by steroid molting hormones, ecdysteroids. The synthesis of ecdysteroids is negatively regulated by molt-inhibiting hormone (MIH) mediated by one or more cyclic nucleotide second messengers. Existing data indicate ecdysteroidogenesis is positively regulated by Ca2+ through the activation of phosphodiesterases (PDEs). The studies presented in this dissertation composed the first report of intracellular Ca2+ measurement in Y-organ cells from any crustacean species. Studies demonstrated that elevated cytosolic Ca2+ levels in Y-organ cells were associated with increased hemolymphatic ecdysteroid titer. Measurement of Ca2+ levels in Y-organ cells in a natural molting cycle …

Consumer And Processor Methods To Control Salmonella And Listeria In Shrimp, Genevieve Anne Edwards

LSU Master's Theses

A common method used by consumers to determine if shrimp are thoroughly cooked when boiling, is to wait until the shrimp float to the top of the water and are pink in color. The purpose of this study was to determine whether the current floating and color cooking method is adequate to ensure the elimination of Listeria and Salmonella species. Furthermore, to determine if processing and storage methods reduce the effectiveness of this method. Shrimp samples were submerged into bacterial suspensions for 30 min then allowed to air dry for 1 hr and color parameters were measured using a colorimeter. …

Biomass And Mass Balance Isotope Content Of Mussel Seep Populations, Philip Martin Riekenberg

LSU Master's Theses

Cold seep mussels, Bathymodiolus childressi, are common cold seep constituents that form large populations at upper continental slope (500-1000 m) cold seep sites in the Northern Gulf of Mexico. These mussels utilize methane present through symbiotic relationships with methanotrophic bacteria. This study uses a coupled isotope technique to determine the relative incorporation of respiratory carbon in the shell as a measure of the availability of methane between different seep sites. This method indicates a higher abundance of methane at the Brine Pool site than at the Bush Hill site which appears significantly more resource limited and that changes in methane …

Modulation Of Mesenchymal Stem Cell Behavior By Nano And Micro-Sized Beta-Tricalcium Phosphate Particles In Suspension And Composite Structures, Lekeith Terrell

LSU Master's Theses

Nano and micro particles have steadily grown in interest for synthetic bone composite structures. Nano and micro sized calcium phosphates especially are of interest because of the osteoinductive behavior of calcium phosphate. Engineered composites incorporating polymers and ceramics, such as poly l-lactic acid (PLLA)/β-TCP, for bone tissue regeneration have been well investigated for their proliferative and osteoinductive abilities. Limited research has been done to thoroughly investigate the effects of various sized β-TCP particles on human mesenchymal stem cell behavior. Foreign bodies are known to elicit an inflammatory and cytotoxic response and several nano-particles are known to elicit cytotoxic and pro-inflammatory …

Evaluation Of Phosphorous And Nitrogen Removal In Alligator And Dairy Wastewater Via Lime And Bentonite Precipitation, Srikanth Bukkapatnam Tirumala

LSU Master's Theses

In many situations, the manure produced by confined animal feeding operations (CAFO) needs to be treated before being land applied in order to prevent negative impacts on the environment. Treatment methods are focused on reducing organics, recovering nitrogen and phosphorous. The purpose of this study is to evaluate the efficacy of burnt-lime (Ca(OH)2) and bentonite clay precipitation system of recovering phosphorous from dairy wastewater and alligator wastewater and trapping any possible emissions of ammonia (NH3). Wastewater samples of flush dairy manure from a collection pit, dairy wastewater from an anaerobic lagoon and alligator wastewater from an anaerobic lagoon were investigated …

Repeatability Of Prolactin Responses To Sulpiride In Mares And Geldings And The Effect Of Pergolide And Cabergoline, Rebekah C. Hebert

LSU Master's Theses

Four experiments were conducted in an effort to develop a method, based on prolactin secretion, for assessing the efficacy and duration of activity of dopaminergic agonists for the treatment of pituitary pars intermedia dysfunction (PPID) in horses. In the first experiment, prolactin response to a low dose of the dopamine antagonist, sulpiride, was generally repeatable in estrogen-primed geldings in winter over 8 every-other-day challenges. It was concluded that estrogen-primed, sulpiride-challenged geldings in winter could serve as a model for the study of potential dopaminergic drugs for the treatment of PPID in horses. The second experiment was performed in the summer …

The Potential Of The Angle Of The First Rib, Head To Tubercle, In Sexing Adult Individuals In Forensic Contexts, Paige Whitney Elrod

LSU Master's Theses

Accurately assessing the sex of an adult human skeleton is fundamental in forming the biological profile used in forensic anthropology (Patil and Mody, 2005). The first rib was chosen due to its distinct shape, compact size and increased sustainability to the taphonomic processes encountered in forensic and bioarchaeological situations. The first rib has been examined in previous studies; however, these studies have focused mainly on the sternal end of the rib. This study looks at the angle created between the tubercle and head and its potential use as an indication of the sex of an individual. This angle, created by …

A Novel Rna Extraction Method For Cyanobacteria, Zenghui Zhang

LSU Master's Theses

Research on production of polyhydroxyalkanoates (PHA) by microorganisms has captured attention over the last two decades, since PHA have similar properties as petroleum-based thermoplastics, yet are close to carbon neutral and made from renewable sources. Cyanobacteria are considered to be good PHA producers because of their simple nutrient requirements (mainly water, sunlight and CO2) and fast cell growth. However, knowledge of metabolisms behind PHA production by cyanobacteria is limited. Therefore, gene expression analysis of cyanobacteria is required to get a thorough understanding at the molecular level, and gene expression analysis requires the extraction of high quality RNA. Extracting high quality …

The Problem And Possibility Of Animal Minds In Brandom's Work: Revisiting Heidegger, Rationality And Normativity, Joel David Musser

LSU Master's Theses

Robert Brandom denies animals implicit reasoning by emphasizing their inability to make inferences explicit, and in so doing, denigrates animals by likening their behavior to that of machines and artifacts. I contest, however, that animals are paradigmatically more than any similarity or analogy to mechanical processing, just as humans are paradigmatically more than any reductive analogy to animals. The human/animal distinction need not come at the cost of ignoring the difference between animals and artifacts, and I believe we can largely subscribe to Brandom’s differentiation of the human in terms of expressionism if we allow that animals can make implicit …

Effects Of Varying Land Use On Headwater Stream Fish Assemblages And In-Stream Habitats In Southwestern Louisiana, Alexandra Marie Fitzgerald

LSU Master's Theses

Although watershed land use effects on in-stream fish habitat and fish-macrohabitat associations have been widely studied in the past, low-gradient, coastal Louisiana streams have been poorly described in the literature. In this thesis, I report the results of a two-year study exploring relationships among regional land use, in-stream physical habitat, and headwater stream fish assemblages. In chapter two, I examined in-stream habitat variables such as depth, flow, and substrate combined with three-pass electrofishing depletion estimates at thirteen 100-m stream sites. I used a combination of principle component analysis and structural equation modeling to determine if trends were present in the …

Impact Of Teaching Style On Student Learning Of Evolution, Laurie Font

LSU Master's Theses

Natural selection is a topic that is laden with misconceptions. These misconceptions are often not addressed, and students can leave a biology classroom with the same incorrect ideas that they entered with. These misconceptions can be identified and addressed by using the Concept Inventory of Natural Selection (CINS). Furthermore, by teaching using methods that encourage hands-on, inquiry based techniques, students are more apt to reconcile these misconceptions and have a deeper understanding of the natural selection process. The goal of my research was to show a positive correlation between reduction in student misconceptions about natural selection and inquiry based activities. …

Ensemble Methods For Malware Diagnosis Based On One-Class Svms, Xing An

LSU Master's Theses

Malware diagnosis is one of today’s most popular topics of machine learning. Instead of simply applying all the classical classification algorithms to the problem and claim the highest accuracy as the result of prediction, which is the typical approach adopted by studies of this kind, we stick to the Support Vector Machine (SVM) classifier and based on our observation of some principles of learning, characteristics of statistics and the behavior of SVM, we employed a number of the potential preprocessing or ensemble methods including rescaling, bagging and clustering that may enhance the performance to the classical algorithm. We implemented the …

The Effects Of Teaching Style On Student Learning Of Dna, Rebecca Branton

LSU Master's Theses

New methods and practices are constantly being introduced in education due to new research that emerges as a push for student achievement increases. We as teachers must adapt to these new ideas to ensure student success. This study was completed to determine if inquiry-based teaching methods would be more beneficial in learning Biology concepts than traditional lecture instruction. The students were divided into two groups, which differed based solely on their instructional format. The activities involved in this study included inquiry-based activities and traditional activities, i.e. PowerPoints, guided notes, experiments and worksheets. The participants in this study, students in a …

Evaluating The Efficacy Of Methoxyfenozide On Louisiana, Texas And The Mid-Southern Soybean Looper Populations, Sebe Anthony Brown

LSU Master's Theses

The soybean looper, Chrysodeixis includens (Walker), is a defoliating insect pest of soybean in the Mid-South and Texas. In 2008, Louisiana producers reported unsatisfactory control of soybean loopers in soybean with methoxyfenozide. In 2009 and 2010, field collections from Louisiana, Missouri, Mississippi and Texas were exposed to discriminating concentrations (0.020 to 5.000 ai ìg/ml) of methoxyfenozide in diet incorporation bioassays. All field colonies were compared to a reference strain LC50 of 0.007 ìg/ml for 2009 and 0.008 ìg/ml for 2010. Louisiana populations exhibited LC50’s of 0.079 ìg/ml and 0.122 ìg/ml for 2009 and 2010, respectively, which were the highest values …

The Moderating Effects Of Perceived Intentionality: Exploring The Relationships Between Ideas Of Reference, Paranoia, And Social Anxiety In Schizotypy, Sean Cameron Morrison

LSU Master's Theses

Ideas of reference (IOR), paranoia, and social anxiety are three common symptoms of schizophrenia-spectrum disorders, which appear to be conceptually related. However, the precise nature of these relationships is unclear. A new measure that assesses perceived intentionality (PI), a social-cognitive bias for perceiving the actions of others during unpleasant social situations as being directed at oneself in an intentionally malicious manner, has provided preliminary evidence for a link between PI and paranoia. The primary aim of this study was to examine the moderating role of PI on the relationships between IOR and paranoia, and between IOR and social anxiety amongst …

A Survey Of Ballistosporic Phylloplane Yeasts In Baton Rouge, Louisiana, Sebastian Albu

LSU Master's Theses

A study documenting basidiomycete yeast biodiversity was conducted in Baton Rouge, Louisiana during 2010 and 2011. Using the spore-fall method, the leaf surfaces of seven ferns were sampled at biweekly intervals. Maximum likelihood phylogenetic analyses of the internal transcribed spacer (ITS) region and the D1/D2 domain of the large subunit (LSU) of nuclear ribosomal DNA were used to identify 463 isolates representing 81 species spanning 12 orders within six classes in Basidiomycota. Nearly 30 of these isolates appear to be species new to science. Data indicate fern leaf developmental stage has an effect on the number of yeasts present. A …

Extending Job Embeddedness Theory To The Family Domain: Development Of A Construct And Measure For Family Embeddedness And Integration Through A Work-Family Balance Perspective, Tatiana H. Toumbeva

LSU Master's Theses

The goal of this study was to extend theory and research on job embeddedness by conceptualizing a parallel phenomenon that also exists in the family domain, referred to here as family embeddedness. Work-family balance perspective was utilized to argue that job and family embeddedness facilitate successful role functioning by guiding the resource allocation process in both the work and family domains. There were two parts to this study. In Phase 1, a measure was developed and a nomological network was established for family embeddedness. In Phase 2, a model was tested to understand the process through which two types of …

Biodegradation And Distribution Of Crude Oil Sampled At Fourchon Beach, Kendall Ray Lemelle

LSU Master's Theses

This study was developed to determine the distribution and fate of crude oil spilled from the Deepwater Horizon oil rig starting on April 24, 2010. Crude oil from this spill contaminated portions of Fourchon Beach, Louisiana which was the study site for this thesis. Understanding the fate processes that affect crude oil once it’s released is important because the compounds that comprise oil can be hazardous to humans and wildlife. Composite and small surface residual ball (SSRB) samples were collected from the supratidal zone of Fourchon Beach and analyzed for PAHs and alkanes. Alkane concentrations decreased significantly over time, while …