Digital Commons Network^™

Rna-Seq Analysis Of The Sclerotinia Homoeocarpa – Creeping Bentgrass Pathosystem, Angela M. Orshinsky, Jinnan Hu, Stephen O. Opiyo, Venu Reddyvari-Channarayappa, Thomas K. Mitchell, Michael J. Boehm

Department of Plant Pathology: Faculty Publications

Sclerotinia homoeocarpa causes dollar spot disease, the predominate disease on highly-maintained turfgrass. Currently, there are major gaps in our understanding of the molecular interactions between S. homoeocarpa and creeping bentgrass. In this study, 454 sequencing technology was used in the de novo assembly of S. homoeocarpa and creeping bentgrass transcriptomes. Transcript sequence data obtained using Illumina’s first generation sequencing-by-synthesis (SBS) were mapped to the transcriptome assemblies to estimate transcript representation in different SBS libraries. SBS libraries included a S. homoeocarpa culture control, a creeping bentgrass uninoculated control, and a library for creeping bentgrass inoculated with S. homoeocarpa and incubated for …

Modeling An Improvement In Phosphorus Utilization In Tropical Agriculture, David Edelstein, David J. Tonjes

Technology & Society Faculty Publications

Studies of Terra Preta soils have generated interest in recreating their fertility elsewhere. Much of the research has focused on soil amendment charcoal (“biochar”). Terra Preta also contains bone fragments, producing a high concentration of phosphorus. Some forecast worldwide declines in phosphorus supplies, and better agricultural system management is required to improve phosphorus use efficiency. A conceptual model is offered to consider the influence of charcoal on bioavailability of phosphorus. The model describes a system where improvements in the chemical and biological condition of the soil result in increased phosphorus availability and cycling. Mechanisms of phosphorus/charcoal interaction are considered, and …

Becoming "Black" In America: Exploring Racial Identity Development Of African Immigrants, Godfried Agyeman Asante

All Graduate Theses, Dissertations, and Other Capstone Projects

This qualitative study critically examined how African immigrants experience racialization and the process of developing Black racial consciousness. Focus group interviews were conducted to sample the collective racial experience among African immigrants. Thematic analysis was used as the basic methodology for analyzing the data. It was discovered that the participants "become African" and also "become Black" during the process of racial identification. "Becoming African" and "Becoming Black" constituted two sets of processes that simultaneously shaped the identity of African immigrants as they assimilated into the United States. From the study it became evident that there was tension between ethnic identification …

Interest And Its Development, K. Ann Renninger, Stephanie Su , '11

Educational Studies Faculty Works

No abstract provided.

Fact Book 2012-13, Western Michigan University

Western Michigan University Fact Books

• General Information
• Enrollment Information
• Institutional Comparison
• Student Information
• Faculty Information
• Budgets and Resources

The Western Michigan University Magazine, Winter 2012, Western Michigan University

Western Michigan University Magazine (1997-present)

• Government and the Economic Crisis: Professor’s book probes the Fed’s role in the U.S. financial market meltdown.
• A History of Honors: The Lee Honors College celebrates 50 years of guiding gifted students.
• Class, a Click Away WMU’s online programs and classes are a popular way to learn—from anywhere in the world.
• ‘Mavericks of American Dance’: Alum’s film on the legendary Joffrey Ballet is to air on PBS.
• App to Fly: The iPad is becoming a cockpit asset in college and industry.
• From Startup to Market: Meet the force behind the Biosciences Research & Commercialization Center at WMU.
• Generational Lessons: Learned …

Faculty Senate Yearbook, 2012-13, Wmu Faculty Senate

WMU Faculty Senate Yearbooks

No abstract provided.

2012 Warbler, Eastern Illinois University

The Warbler

The 2012 Warbler, yearbook of Eastern Illinois University

Research Annual Report 2012, Children's Mercy Hospital

Research Annual Reports

Annual report of the research at Children's Mercy Hospital in Kansas City MO, a pediatric medical center.

The Kamlet Laboratories Collection At The University Of South Florida, Dean F. Martin, Karina Bidani

Chemistry Faculty Publications

Jonas Kamlet (1914-1960) and his wife Edna (1915- 2011) founded the Kamlet Laboratory (as it was then called) in 1941 (I). It was in many ways a pioneering consulting laboratory that was unique for its approach and creativity. In 2006, the collected papers of the Kamlet Laboratories that were housed in two storage units in Sarasota, Florida, were donated to the University of South Florida (USF) Library, Tampa Campus, as noted elsewhere (I). This paper describes the background of the laboratory and indicates the potential value of the material in the Kamlet Chemical Laboratories Collection. The collection came to USF …

Coplanar Pcb77 And Angii Induced Vascular Disorders, Madhura Parulkar

Theses and Dissertations--Nutritional Sciences

Previous studies demonstrated that coplanar PCBs promote inflammation by release of pro-inflammatory cytokines like TNF, MCP-1, and VCAM-1 from endothelial cells as well as adipocytes. Also these PCBs at small doses may contribute to the development of obesity by inducing adipocyte differentiation. Obesity is a known risk factor that promotes cardiovascular disorders like atherosclerosis and AAAs. Evidence shows Ang II, a component of the RAS, leads to the formation of atherosclerosis and AAAs in both normal as well as hyperlipidemic mice. Earlier studies in our laboratory have also shown that coplanar PCB-77 promotes atherosclerotic lesion formation in ApoE-/- mice. The …

Associations Between Serum Concentrations Of Polychlorinated Biphenyls, Serum Carotenoids, And The Probability Of Metabolic Syndrome In The National Health And Nutrition Examination Survey 2003-2004, Carolyn R. Hofe

Theses and Dissertations--Nutritional Sciences

Diabetes and cardiovascular disease are leading causes of death and disability in the United States. These chronic diseases are clinical sequelae of metabolic syndrome (MetS), a condition that affects approximately one-third (1/3) of American adults. Metabolic syndrome occurs in response to environmental and genetic influences, among them food intake, a sedentary lifestyle, BMI, advancing age, and exposure to persistent organic pollutants (POPs). POPs are known to cause endocrine disruption and PCBs cause oxidative stress, disrupt endothelial cell integrity, and promote atherosclerosis. Nutrition plays a significant role in the prevention and management of these chronic diseases and has been shown to …

Deficiency Of Ace2 In Bone-Marrow-Derived Cells Increases Expression Of Tnf-Α In Adipose Stromal Cells And Augments Glucose Intolerance In Obese C57bl/6 Mice, Sean E. Thatcher, Manisha Gupte, Nicholas Hatch, Lisa A. Cassis

Graduate Center for Nutritional Sciences Faculty Publications

Deficiency of ACE2 in macrophages has been suggested to promote the development of an inflammatory M1 macrophage phenotype. We evaluated effects of ACE2 deficiency in bone-marrow-derived stem cells on adipose inflammation and glucose tolerance in C57BL/6 mice fed a high fat (HF) diet. ACE2 activity was increased in the stromal vascular fraction (SVF) isolated from visceral, but not subcutaneous adipose tissue of HF-fed mice. Deficiency of ACE2 in bone marrow cells significantly increased mRNA abundance of F4/80 and TNF-α in the SVF isolated from visceral adipose tissue of HF-fed chimeric mice, supporting increased presence of inflammatory macrophages in adipose tissue. …

Table Of Contents For Volume 100, Issue 3, Kentucky Law Journal

Kentucky Law Journal

No abstract provided.

Kentucky Water Resources Research Institute Annual Technical Report Fy 2011, Kentucky Water Resources Research Institute, University Of Kentucky

KWRRI Annual Technical Reports (USGS’s 104b Grant Program)

The FY2011 Annual Technical Report for Kentucky consolidates reporting requirements for the Section 104(b) base grant award into a single document that includes; 1) a synopsis of each research project that was conducted during the period, 2) citations for related publications, reports, and presentations, 3) a description of information transfer activities, 4) a summary of student support during the reporting period, and 5) notable awards and achievements during the year.

Project 2011KY166B (Sewage to fertilizer: a proposed solution to water pollution) was not initiated because the principal investigator (Dr. Rebecca Evans Kelley) resigned from the Department of Biological Sciences at …

Model Ordinance For Development On Karst In Kentucky: Guidance For Construction On Karst Terrain And The Reduction Of Property Damage And Threat To Human Health Resulting From Karst Geologic Hazard, James C. Currens

Information Circular--KGS

I have dealt with hundreds of incidents of karst-related geohazards; some have caused major damage to buildings and infrastructure. Although cases are largely limited to the ground surface being made unusable, a significant number of structures are damaged by karst flooding or cover collapse each year, which is devastating to families who have lost their homes. Most of these events should never have happened, because the karst hazard could have been avoided by selecting a better building site or designing the building to withstand the damage from the hazard. Furthermore, most of the planning authorities I have had experience with …

5q Minus Myelodysplasia Associated With Multiple Epithelioid Granulomas Within Conventional Renal Cell Carcinoma, Rahul G. Matnani, Roshan K Patel, Stephen E Strup, Rouzan Karabakhtsian

Pathology and Laboratory Medicine Faculty Publications

A 69-year-old Caucasian female, with a previous diagnosis of 5q minus myelodysplastic syndrome, presented with conventional renal cell carcinoma (RCC) associated with multiple-epithelioid nonnecrotizing granulomas. Two previous reports of sarcoidosis, primarily involving the lung and skin, have been described in patients with 5q minus myelodysplasia. A cluster of closely linked genes encoding for cytokines such as IL-4, IL-5, and IL-3 are present on chromosome 5q. Hence, in sarcoidosis, cytokine imbalances associated with the deletion of these cytokine genes have been postulated. However, an occurrence of epithelioid granulomas within a carcinoma, in preexisting clonal myelodysplastic syndrome, has not been described. The …

“The Play’S The Thing”: Theatre As A Scholarly Meeting Ground In Age Studies, Valerie Barnes Lipscomb

English Sarasota Manatee Campus Faculty Publications

Addressing three current critical turns in gerontology, this article proposes the theatre as a fertile ground for various theoretical angles in age studies - including the performative on and off stage, the narrative in the script and the critical questioning of age and ageism in the multiple realities of performance. Beginning from a shared site in the theatre, researchers may be able to establish greater common ground, resulting not only in multi-disciplinary efforts but also in truly interdisciplinary work. With a foundation in performance studies, this article suggests promising directions for age studies and theatre scholarship by examining three aspects …

Levels Of Pahs In The Waters, Sediments, And Shrimps Of Estero De Urias, An Estuary In Mexico, And Their Toxicological Effects, Foday M. Jaward, Henry A. Alegria, Jose G. Galindo Reyes, Armando Hoare

Environmental and Occupational Health Faculty Publications

PAHs were measured in water, sediment, and shrimps of Estero de Urias, an estuary in Sinaloa, Mexico, during the rainy and dry seasons, and analyzed for eleven PAHs routinely detected in samples. Phenanthrene was the most dominant congener in the water, sediment, and shrimp samples comprising about 38, 24, and 25%, respectively, of the eleven PAHs detected, followed by pyrene and naphthalene in water and sediment samples, and pyrene and fluorine in the shrimp samples. Total PAH concentrations ranged from 9 to 347 ng/L in water, 27 to 418 ng/g in sediments, and 36 to 498 ng/g in shrimps. The …

Mixed-Effects Tobit Joint Models For Longitudinal Data With Skewness, Detection Limits, And Measurement Errors, Getachew A. Dagne, Yangxin Huang

Epidemiology and Biostatistics Faculty Publications

Complex longitudinal data are commonly analyzed using nonlinear mixed-effects (NLME) models with a normal distribution. However, a departure from normality may lead to invalid inference and unreasonable parameter estimates. Some covariates may be measured with substantial errors, and the response observations may also be subjected to left-censoring due to a detection limit. Inferential procedures can be complicated dramatically when such data with asymmetric characteristics, left censoring, and measurement errors are analyzed. There is relatively little work concerning all of the three features simultaneously. In this paper, we jointly investigate a skew-t NLME Tobit model for response (with left censoring) …

Hot, Crowded, And Legal: A Look At Industrial Agriculture In The United States And Brazil, David N. Cassuto, Sarah Saville

Animal Law Review

Over the last sixty years, industrial agriculture has expanded in the United States and throughout the world, including in Brazil. Any benefit this expansion has brought comes at significant environmental and social costs. Industrial agriculture is a leading contributor to global climate change, air and water pollution, deforestation, and dangers in the workplace. This Article discusses the impact of industrial animal agriculture in the U.S. and Brazil. It also examines the laws pertaining to industrial agriculture in both countries and provides a comparative analysis of the two legal regimes. Finally, this Article concludes with the observation that although the price …

2011 Legislative And Administrative Review, Patrick Graves, Keith Mosman, Shayna Rogers

Animal Law Review

It is my pleasure to introduce Animal Law’s fourteenth annual Legislative and Administrative Review. The 2011 Legislative and Administrative Review analyzes some of the year’s most groundbreaking developments in animal-related state and federal legislation, such as federal regulations of genetically engineered fish and attempts by state legislatures to overturn animal-related citizen initiatives.

Additionally, for the first time in Animal Law’s history, this year’s Review also includes an analysis of some of the most important animal-related administrative law developments of the year. Because many decisions impacting animals occur in the administrative arena, it is our hope that the administrative section complements …

The Universal Declaration Of Animal Rights Or The Creation Of A New Equilibrium Between Species, Jean-Marc Neumann

Animal Law Review

This Essay is a translation of the author’s original French text. It examines the Universal Declaration of Animal Rights of 1978, which lays out fundamental rights for animals in fourteen articles. This Essay explores the origins of and influences behind the original Declaration, as well as details the changes which were brought to it in a revised version in 1989. It then examines the scope of the Declaration and why it has not had the far-reaching implications its authors once hoped for. Finally, this Essay questions what the Declaration means for the future of animal rights and whether the document …

Expression Of Cadherin-11 During Organogenesis In The Chick Embryo, Kacie D. Flaherty, Alicia F. Paulson, Ashley L. Adamson, Darrell J. Wiens

Faculty Work

Cadherin-11 (cad-11) is primarily a mesenchymal cadherin that appears in delaminating neural crest cells. Its expression correlates with morphogenetic events and the pattern has been studied in mouse, rat and Xenopus embryos, but not during avian organogenesis. Our purpose was to investigate this pattern in the chick embryo during organogenesis using immunolocalization and in situ hybridization. Cad-11 was expressed in mesenchyme around the pharynx and aortic arches, eyes, auditory vesicles, lung buds, stomach, and nasal placodes. Neural expression included some cranial ganglia and also new neuroepithelium within the tail bud region undergoing secondary neurulation. We also found expression in epithelia …

Gram Stains: A Resource For Retrospective Analysis Of Bacterial Pathogens In Clinical Studies, Usha Srinivasan, Sreelatha Ponnalurl, Lisa Villareal, Brenda Gillespie, Ai Wen, Arianna Miles, Brigette Bucholz, Carl F. Marrs, Ram K. Iyer, Dawn Misra, Betsy Foxman

Faculty Work

We demonstrate the feasibility of using qPCR on DNA extracted from vaginal Gram stain slides to estimate the presence and relative abundance of specific bacterial pathogens. We first tested Gram stained slides spiked with a mix of 108 cfu/ml of Escherichia coli and 105cfu/ml of Lactobacillus acidophilus. Primers were designed for amplification of total and species-specific bacterial DNA based on 16S ribosomal gene regions. Sample DNA was pre-amplified with nearly full length 16S rDNA ribosomal gene fragment, followed by quantitative PCR with genera and species-specific 16S rDNA primers. Pre-amplification PCR increased the bacterial amounts; relative proportions of Escherichia coli …

Recent Developments In The Interactions Between Caveolin And Pathogens, Fabiana S. Machado, Nilda E. Rodriguez, Daniel Adesse, Luciana R. Garzoni, Lisia Esper, Michael P. Lisanti, Robert D. Burk, Chris Albanese, Koenraad Van Doorslaer, Louis M. Weiss, Fnu Nagajyothi, Joshua D. Nosanchuk, Mary E. Wilson, Herbert B. Tanowitz

Faculty Work

The role of caveolin and caveolae in the pathogenesis of infection has only recently been appreciated. In this chapter, we have highlighted some important new data on the role of caveolin in infections due to bacteria, viruses and fungi but with particular emphasis on the protozoan parasites Leishmania spp., Trypanosoma cruzi and Toxoplasma gondii. This is a continuing area of research and the final chapter has not been written on this topic.

Physiochemical Characteristics Contributing To The Cytotoxicity Of Transition Metal Oxides, Chi-Heng Wu

Masters Theses

"In the past ten years nanotechnology has not only evolved to play a prominent role in our economy but also increased the concern over potential adverse effects caused by nanomaterials to human health and the environment. Nanotoxicity is to understand the nature and origin of the toxicity imposed by nanomaterials. Studies from our laboratory have shown that nanoparticle induces oxidative stress, perturbs calcium homeostasis, alter gene expression, and produces pro-inflammatory responses. We also identified a trend of toxicity: TiO₂ < Cr₂O₃ < Fe₂O₃ < Mn₂O₃ < NiO < ZnO < CuO. We then asked a question: what are physiochemical factors of transition metal nanoparticles that contributed to this increasing cytotoxicity. In this thesis I investigated the correlation between physicochemical properties and toxicity of the transition metal oxides in the 4th Period of the Periodic Table of Elements. Particle size, BET surface area, point of zero charge, metal dissolution, and degree of surface adsorption of transition metal oxide nanoparticles were measured. There were no increasing trends in both particle size and specific surface area. The point of zero charge showed an increasing trend as TiO₂ < Cr₂O₃ < Fe₂O₃ < NiO < CuO = ZnO < Mn₂O₃. The number of available binding sites of nanoparticle showed an increasing trend as Cr₂O₃ > ZnO > CuO > NiO > Fe₂O₃ > Mn₂O₃ > TiO₂. The degree of adsorption on the surface of nanoparticles showed an increasing trend with atomic …

Interring The Pioneer Invention Doctrine, Brian J. Love

North Carolina Law Review

No abstract provided.

Michigan Academician, Volume 40, Issue 3

Michigan Academician

No abstract provided.

Annual Reports Of The Town Of Greenland, New Hampshire For The Fiscal Year Ending December 31, 2011 As Compiled By The Town Officers., Greenland Town Representatives

Greenland, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.