Digital Commons Network^™

Proving Medical Child Abuse: The Time Is Now For Ohio To Focus On The Victim And Not The Abuser, Tiffany S. Allison

Journal of Law and Health

Part I of this Note will discuss the history of Munchausen's Syndrome by Proxy and how the medical community is trying to make the general public aware of medical child abuse. Part II provides a history of Munchausen's Syndrome by Proxy and medical child abuse. It also highlights the differences in how litigation was previously handled under the nomenclature of Munchausen's Syndrome by Proxy and how litigation should be handled in the future under the nomenclature of medical child abuse. Part III identifies Ohio's current statutes and federal legislation that have an effect on child abuse. Part III also identifies …

Sex, Work, And The Feminist Erasure Of Class, Brooke M. Beloso

Scholarship and Professional Work - LAS

In this essay, I trace the contemporary feminist debate on prostitution to the period in which Catharine MacKinnon and Gayle Rubin deemed Marxism inadequate to the task of theorizing women’s oppression. In seeking to surmount this perceived inadequacy, both thinkers counterposed alternative theoretical frameworks for analyzing women’s oppression that nonetheless relied upon certain of Marxism’s central tenets. In a reliance that took the form of strikingly similar translations of Marxism foregrounding what came to be known as radical feminism (in the case of MacKinnon) and queer theory (in the case of Rubin), both theorists problematically render class as, respectively, gender …

Proceedings Of The Design Research Society International Conference, 2012. Vol. 3: Re-Search - Uncertainty, Contradiction And Value, Praima Israsena, Juthamas Tangsantikul, David Durling

DRS Conference Volumes

The proceedings of the 2012 Design Research Society International Conference hosted by Chulalongkorn University in Bangkok, Thailand. Submissions covered extensive themes and emerging research that is broad in scope and depth, submitted with the conference theme of Re-Search: uncertainty, contradiction and value, in mind. The initial abstract submission was high with approximately 550 initial abstracts submitted. Of the 288 full papers submitted, 183 papers were accepted and of these 154 papers were presented at the conference along with an additional 23 poster presentations.

Removal Of Uracil By Uracil Dna Glycosylase Limits Pemetrexed Cytotoxicity: Overriding The Limit With Methoxyamine To Inhibit Base Excision Repair, A. D. Bulgar, L. D. Weeks, Y. Miao, S. Yang, Yan Xu, C. Guo, S. Markowitz, N. Oleinick, S. L. Gerson, Lili Liu

Chemistry Faculty Publications

Uracil DNA glycosylase (UDG) specifically removes uracil bases from DNA, and its repair activity determines the sensitivity of the cell to anticancer agents that are capable of introducing uracil into DNA. In the present study, the participation of UDG in the response to pemetrexed-induced incorporation of uracil into DNA was studied using isogenic human tumor cell lines with or without UDG (UDG+/+/UDG−/−). UDG−/− cells were very sensitive to pemetrexed. Cell killing by pemetrexed was associated with genomic uracil accumulation, stalled DNA replication, and catastrophic DNA strand breaks. By contrast, UDG+/+ cells were >10 times more resistant to pemetrexed due to …

A Review Of Above Ground Necromass In Tropical Forests, Michael W. Palace, Michael Keller, George C. Hurtt, Steve Frolking

Earth Sciences

No abstract provided.

Uis Bulletin, Volume 53, No. 1 & 2, 2010, Fadi Nader

UIS Bulletin

Contents: Message from the Secretary General -- Minutes of the 2010 Annual UIS Bureau Meeting -- Report on the 11th International Symposium on Pseudokarst -- Spéléo-Secours: 3ième Rencontre des pays des karsts alpins -- Argentina: la UIS acompaña a la Red de Áreas Protegidas Espeleológicas -- UIS Bureau 2009-2013 -- National Delegates and Substitutes -- UIS Departments, Commissions, and Working Groups -- Contributions and Bank Account

The History Of Inequality In Education, Amity L. Noltemeyer, Julie Mujic, Caven S. Mcloughlin

History Faculty Publications

The purpose of this chapter is to consider a sampling of the critical events that demonstrate this history of inequity, with the understanding that they have contributed to the current status of American schools. To this end, we will explore relevant events related to the education of individuals of different racial, gender, language, and disability backgrounds. We do not intend to provide an exhaustive overview of the history of American education, nor will we provide a detailed account of the history of equity in the broader society outside of the educational sector. Rather, we will provide a cursory glimpse at …

Hyponatremia In The 2009 161-Km Western States Endurance Run, Martin D. Hoffman, Kristin J. Stuempfle, Ian R. Rogers, Louise B. Weschler, Tamara Hew-Butler

Health Sciences Faculty Publications

Purpose:To determine the incidence of exercise-associated hyponatremia (EAH), the associated biochemical measurements and risk factors for EAH, and whether there is an association between postrace blood sodium concentration ([Na⁺]) and changes in body mass among participants in the 2009 Western States Endurance Run, a 161-km mountain trail run.

Methods: Change in body mass, postrace [Na⁺], and blood creatine phosphokinase (CPK) concentration, and selected runner characteristics were evaluated among consenting competitors.

Results: Of the 47 study participants, 14 (30%) had EAH as defined by a postrace [Na⁺] /L. Postrace [Na^{+ …}

Estimating Covariation Between Vital Rates: A Simulation Study Of Connected Vs. Separate Generalized Linear Mixed Models (Glmms), Margaret Ek Evans, Kent E. Holsinger

EEB Articles

Covariation between vital rates is recognized as an important pattern to be accounted for in demographic modeling. We recently introduced a model for estimating vital rates and their covariation as a function of known and unknown effects, using generalized linear mixed models (GLMM’s) implemented in a hierarchical Bayesian framework (Evans et al. 2010). In particular, this model included a model-wide year effect (YEAR) influencing all vital rates, which we used to estimate covariation between vital rates due to exogenous factors not directly included in the model. This YEAR effect connected the GLMMs of vital rates into one large model; we …

Theory And Design Of Nature Reserves, Kent E. Holsinger

EEB Articles

Notes that accompany a lecture on reserve design when I taught a graduate level course in conservation biology. These notes provide an introductory overview to the theory and design of nature reserves.

The Effect Of Historical Legacy On Adaptation: Do Closely Related Species Respond To The Environment In The Same Way?, Rachel Prunier, Kent E. Holsinger, Jane E. Carlson

EEB Articles

The many documented examples of parallel and convergent evolution in similar environments are strong evidence for the role of natural selection in the evolution of trait variation. However, species may respond to selection in different ways; idiosyncrasies of their evolutionary history may affect how different species respond to the same selective pressure. To determine whether evolutionary history affects trait-environment associations in a recently diverged lineage, we investigated within-species trait-environment associations in the white proteas, a closely related monophyletic group. We first used MANOVAs to determine the relative importance of shared response to selection, evolutionary history, and unique responses to selection …

Salinity Preference Of Alaskan Threespine Stickleback: Test For Divergence In Halotaxis Between Ancestral And Landlocked Populations, David Fryxell, Eric T. Schultz

EEB Articles

Glacial retreat during the Pleistocene caused landlocking of anadromous Alaskan threespine stickleback, Gasterosteus aculeatus, furnishing a natural ‘experiment’ in osmoregulatory divergence. The objective of this study was to assess the effects of individual acclimation and population divergence on salinity preference. Full-sibling families of marine, anadromous, and freshwater-landlocked populations of stickleback were reared in common environments until 3 weeks post-hatch, then were split and acclimated to low or high salinity. At 6 to 8 weeks of age the six experimental groups were tested for salinity preference in a tank that offers fish a choice of compartments with different salinities arranged …

A General Overview Of Afro-American History, George C. Wright

President Emeritus George C. Wright Speeches

No abstract provided.

Comparing Functional Outcomes On Open Reduction And Internal Fixation For Acute Perilunate Dislocation And Fracture-Dislocations: A Systematic Review, Melissa Mundy Allen

MUSC Theses and Dissertations

Introduction: Outcomes based research on trauma-related orthopaedic injuries is imperative for gauging the effectiveness of current surgical procedures and thereby maximizing the patient's functional status. In patients sustaining perilunate dislocations (PLD) and fracture-dislocations (PLFD) following a traumatic fall on an outstretched hand, early open reduction and internal fixation (ORIF) is widely considered the standard of care for acute cases, but evidence supporting optimal techniques and materials is limited in a body of literature consisting mainly of small retrospective case series and expert opinion. The aims of this study were to compare functional outcomes of PLD and PLFD by surgical technique …

The Role Of Human Papillomavirus In Human Immunodeficiency Virus Acquisition In Men Who Have Sex With Men: A Review Of The Literature, Brandon Brown, Mariam Davtyan, Jerome T. Galea, Erica Chow, Segundo Leon, Jeffrey D. Klausner

Social Work Faculty Publications

Human Papillomavirus (HPV) infection is the most common sexually transmitted infection (STI) worldwide. Incidence rates of HPV infection among human immunodeficiency virus (HIV)-infected individuals are well documented and are several-fold higher than among HIV-uninfected individuals. Few studies have demonstrated an increased risk for acquiring HIV infection in those with HPV infection, and this risk seems to be higher when HPV strains are of high-risk oncogenic potential. The estimated prevalence of high-risk oncogenic HPV infection is highest in men who have sex with men (MSM), a particularly vulnerable group with high prevalence rates of HIV infection and other STIs. In this …

Updates From The Regional Human Rights Systems, Anna Taylor, Matthew Lopas, Sarone Solomon

Human Rights Brief

No abstract provided.

Session Four: Institutionalizing Medical Documentation At The National Level, Victor Madrigal-Borloz, Loreine Dela Cruz, Sebnem Korur Fincanci, Rusudan Beriashvili, Suzanne Jabbour, Sana Hamzeh

Human Rights Brief

No abstract provided.

The Club-K Anti-Ship Missile System: A Case Study In Perfidy And Its Repression, Robert Clarke

Human Rights Brief

No abstract provided.

Reflections On Science And Technoscience, Hugh Lacey

Philosophy Faculty Works

Technoscientific research, a kind of scientific research conducted within the decontextualized approach (DA), uses advanced technology to produce instruments, experimental objects, and new objects and structures, that enable us to gain knowledge of states of affairs of novel domains, especially knowledge about new possibilities of what we can do and make, with the horizons of practical, industrial, medical or military innovation, and economic growth and competition, never far removed from view. The legitimacy of technoscientific innovations can be appraised only in the course of considering fully what sorts of objects technoscientific objects are: objects that embody scientific knowledge confirmed within …

Athletics Panels, Historical Administration

Building Memories - Docs

No abstract provided.

Building Memories - Design Brief, Historical Administration

Building Memories - Docs

No abstract provided.

Building Memories - Exhibit Booklet, Historical Administration

Building Memories - Docs

No abstract provided.

Resuscitating Bad Science: Eugenics Past And Present, Ann G. Winfield

Education Faculty Publications

No abstract provided.

Topological Theory In Bioconstructivism, John Shannon Hendrix

Architecture, Art, and Historic Preservation Faculty Publications

In the essay “Landscapes of Change: Boccioni’s Stati d’animo as a General Theory of Models,” in Assemblage 19, 1992, Sanford Kwinter proposed a number of theoretical models which could be applied to computer-generated forms in Bioconstructivism. These included topological theory, epigenesis, the epigenetic landscape, morphogenesis, catastrophe and catastrophe theory. Topological theory entails transformational events or deformations in nature which introduce discontinuities into the evolution of a system. Epigenesis entails the generation of smooth landscapes, in waves or the surface of the earth, for example, formed by complex underlying topological interactions. The epigenetic landscape is the smooth forms of relief which …

Persistent Systemic Inflammation Is Associated With Poor Clinical Outcomes In Copd: A Novel Phenotype, Alvar Agustí, Lisa D. Edwards, Stephen I. Rennard, William Macnee, Ruth Tal-Singer, Bruce E. Miller, Jørgen Vestbo, David A. Lomas, Peter M.A. Calverley, Emiel Wouters, Courtney Crim, Julie C. Yates, Edwin K. Silverman, Harvey O. Coxson, Per Bakke, Ruth J. Mayer, Bartolome Celli, Evaluation Of Copd Longitudinally To Identify Predictive Surrogate Endpoints (Eclipse) Investigators

Journal Articles: Pulmonary & Critical Care Med

BACKGROUND: Because chronic obstructive pulmonary disease (COPD) is a heterogeneous condition, the identification of specific clinical phenotypes is key to developing more effective therapies. To explore if the persistence of systemic inflammation is associated with poor clinical outcomes in COPD we assessed patients recruited to the well-characterized ECLIPSE cohort (NCT00292552).

METHODS AND FINDINGS: Six inflammatory biomarkers in peripheral blood (white blood cells (WBC) count and CRP, IL-6, IL-8, fibrinogen and TNF-α levels) were quantified in 1,755 COPD patients, 297 smokers with normal spirometry and 202 non-smoker controls that were followed-up for three years. We found that, at baseline, 30% of …

“After The Apple”: Female Sexuality In The Writings Of Emilia Pardo Bazán, Susan Walter

Decimonónica

The Biblical story of creation in which Adam and Eve are deceived by the serpent is recognized widely as one of the foundational stories of Western culture. The story’s importance is asserted by many scholars, including Elaine Pagels in her groundbreaking study Adam, Eve and the Serpent: “[T]he biblical creation story, like the creation stories of other cultures, communicates social and religious values and presents them as if they were universally valid” (xx). In this same study Pagels suggests that Christians have interpreted the story of “Genesis” in various ways over the centuries, finding in it important teachings about …

Reinterpreting Hysteria Under Patriarchy In Emilia Pardo Bazán’S “La Novia Fiel” And “Error De Diagnóstico”, Jennifer Smith

Decimonónica

In the nineteenth century there was an explosion of medical discourses on the illness of hysteria, particularly in relation to women. While there were many theories on the origin and nature of the disease that were circulating throughout Spain in the nineteenth century, the prevailing theory was that the cause of hysteria was the female sexual reproductive organs and that only women suffered from the disease (Jagoe, “Sexo” 341- 43). In fact, some Spanish doctors, such as Baltasar de Viguera, considered by many to be Spain’s first gynecologist, continued to subscribe to ancient Greek conceptions of the disease as an …

Predicting Protein Interactions By Brownian Dynamics Simulations, Xuan-Yu Meng, Yu Xu, Hong Zhang, Mihaly Mezei, Meng Cui

Physiology and Biophysics Publications and Presentations

We present a newly adapted Brownian-Dynamics (BD)-based protein docking method for predicting native protein complexes. The approach includes global BD conformational sampling, compact complex selection, and local energy minimization. In order to reduce the computational costs for energy evaluations, a shell-based grid force field was developed to represent the receptor protein and solvation effects. The performance of this BD protein docking approach has been evaluated on a test set of 24 crystal protein complexes. Reproduction of experimental structures in the test set indicates the adequate conformational sampling and accurate scoring of this BD protein docking approach. Furthermore, we have developed …

Wildlife, Water Quality, And The Public Trust Doctrine: A Means Of Enforcing Agricultural Nonpoint Source Pollution Management Plans, Veronique Jarrell-King

Villanova Environmental Law Journal (1991 - )

No abstract provided.

The Molecular Mechanism By Which Pip2 Opens The Intracellular G-Loop Gate Of A Kir3.1 Channel, Xuan-Yu Meng, Hong-Xing Zhang, Diomedes E. Logothetis, Meng Cui

Physiology and Biophysics Publications and Presentations

Abstract

Inwardly rectifying potassium (Kir) channels are characterized by a long pore comprised of continuous transmembrane and cytosolic portions. A high-resolution structure of a Kir3.1 chimera revealed the presence of the cytosolic (G-loop) gate captured in the closed or open conformations. Here, we conducted molecular-dynamics simulations of these two channel states in the presence and absence of phosphatidylinositol bisphosphate (PIP₂), a phospholipid that is known to gate Kir channels. Simulations of the closed state with PIP₂ revealed an intermediate state between the closed and open conformations involving direct transient interactions with PIP₂, as well as …