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The Alestle - Vol. 65 No. 14 - 11/29/2012, Southern Illinois University Edwardsville

The Alestle

Vol. 65 No. 14

Sandspur, Vol 119, No 09, November 29, 2012, Rollins College

The Rollins Sandspur

Rollins College student newspaper, written by the students and published at Rollins College. The Sandspur started as a literary journal.

Curriculum Minutes 11/29/2012, Curriculum Committee

Curriculum Committee Minutes

No abstract provided.

The Daily Gamecock, Thursday, November 29, 2012, University Of South Carolina, Office Of Student Media

November

No abstract provided.

Divergent Carbon Dynamics Under Climate Change In Forests With Diverse Soils, Tree Species, And Land Use Histories, Robert M. Scheller, Alec M. Kretchun, Steve Van Tuyl, Kenneth L. Clark, Melissa S. Lucash, John Hom

Environmental Science and Management Faculty Publications and Presentations

Accounting for both climate change and natural disturbances—which typically result in greenhouse gas emissions—is necessary to begin managing forest carbon sequestration. Gaining a complete understanding of forest carbon dynamics is, however, challenging in systems characterized by historic over-utilization, diverse soils and tree species, and frequent disturbance. In order to elucidate the cascading effects of potential climate change on such systems, we projected forest carbon dynamics, including soil carbon changes, and shifts in tree species composition as a consequence of wildfires and climate change in the New Jersey pine barrens (NJPB) over the next 100 years. To do so, we used …

Localizing Brain Regions Associated With Female Mate Preference Behavior In A Swordtail, Ryan Y. Wong, Mary E. Ramsey, Molly E. Cummings

Biology Faculty Publications

Female mate choice behavior is a critical component of sexual selection, yet identifying the neural basis of this behavior is largely unresolved. Previous studies have implicated sensory processing and hypothalamic brain regions during female mate choice and there is a conserved network of brain regions (Social Behavior Network, SBN) that underlies sexual behaviors. However, we are only beginning to understand the role this network has in pre-copulatory female mate choice. Using in situ hybridization, we identify brain regions associated with mate preference in female Xiphophorus nigrensis, a swordtail species with a female choice mating system. We measure gene expression in …

Role Of Tyrosyl-Dna Phosphodiesterase (Tdp 1) On Repair Of 3′-Phosphoglycolate (3′- Pg) Terminated Dna Double-Strand Breaks (Dsbs) And In Response To Oxidative Stress, Tong Zhou

Theses and Dissertations

DNA DSBs are most toxic to cells because they can lead to genomic rearrangements and even cell death. Most DSBs induced by ionizing radiation or radiomimetic drugs such as calicheamicin and bleomycin, bear 3′-phosphate or 3′- PG moieties that must be removed to allow subsequent gap filling and ligation. DSBs can be repaired by two main pathways: the homologous recombination (HR) pathway and the non-homologous end-joining (NHEJ) pathway, NHEJ is the primary repair pathway in mammalian cells. While HR repairs single strand breaks (SSBs) or DSBs accurately by using an undamaged copy of the sequence mostly at late S phase …

Costs And Use Of Oral Anti-Cancer Medications Among Senior Medicare Part D Beneficiaries, Nantana Kaisaeng

Theses and Dissertations

Oral cancer drugs are branded and expensive medications that generally do not have generics available. The restrictions of the Medicare Part D program, including the coverage gap and high cost-sharing, and the high cost of oral chemotherapy may lead to patients’ non-adherence to medication. Few studies have examined the cost and utilization of oral anti-cancer medications. This study will be the first to examine the costs associated with the use of oral anti-cancer medications and the impact of cost-sharing and type of prescription drug subsidy on medication discontinuation in the Medicare Part D elderly population. Objectives: To determine the usage …

Washington State Dependency Best Practices Report, Justice Bobbe J. Bridge, Michelle Ressa, Jacob D'Annunzio, Hathaway Burden, Dr. Sheri L. Hill, Lisa Kelly, Rose Wentz

Books

The judge's work in child abuse and neglect cases is among the most challenging of any judicial proceeding. The complexities are substantial. Such cases depend upon the exercise of discretion and good judgment together with the application of sound legal principles. The judge must call upon his or her most cherished skills—objectivity, wisdom, patience, and foresight—in circumstances of acute stress. Lives are literally at stake—the lives of the most vulnerable children and youth in our communities and the lives of families wracked by generations of poverty and despair. Families, children, and youth who have experienced intense trauma; who may be …

The Principal Genetic Determinants For Nasopharyngeal Carcinoma In China Involve The Hla Class I Antigen Recognition Groove, Minzhong Tang, J. A. Lautenberger, Xiaojiang Gao, Efe Sezgin, Sher L. Hendrickson, Jennifer L. Troyer, Victor A. David, Li Guan, Carl Mcintosh, Xiuchan Guo, Yuming Zheng, Jian Liao, Hong Deng, Michael Malasky, Bailey Kessing, Cheryl Winkler, Mary Carrington, Guy De The, Yi Zeng, Stephen J. O'Brien

Biology Faculty Articles

Nasopharyngeal carcinoma (NPC) is an epithelial malignancy facilitated by Epstein-Barr Virus infection. Here we resolve the major genetic influences for NPC incidence using a genome-wide association study (GWAS), independent cohort replication, and high-resolution molecular HLA class I gene typing including 4,055 study participants from the Guangxi Zhuang Autonomous Region and Guangdong province of southern China. We detect and replicate strong association signals involving SNPs, HLA alleles, and amino acid (aa) variants across the major histocompatibility complex-HLA-A, HLA –B, and HLA -C class I genes (P_{HLA-A-aa-site-62}= 7.4×10⁻²⁹; P _{HLA-B-aa-site-116}= 6.5×10⁻¹⁹; P _{HLA-C-aa-site-156} = 6.8×10 …

New Technologies For Whole Wheat Processing: Addressing Milling And Storage Issues, Andres F. Doblado-Maldonado

Department of Food Science and Technology: Dissertations, Theses, and Student Research

Whole wheat flour production and demand has increased dramatically during the last decade due to evidence supporting the benefits of whole grains in the diet. Hence, the food industry has provided a wide variety of new whole grain products. There are unique challenges that accompany whole wheat flour production, especially related to milling and storage. The present thesis provides new strategies on the adaptation of new technologies to overcome whole wheat processing issues. These issues are first discussed in a literature review and then followed by three research studies. In the first study, retail whole wheat flours were evaluated for …

The Genomes Of The Fungal Plant Pathogens Cladosporium Fulvum And Dothistroma Septosporum Reveal Adaptation To Different Hosts And Lifestyles But Also Signatures Of Common Ancestry., Pierre J.G.M. De Wit, Ate Van Der Burgt, Bilal Ökmen, Ionnis Stergiopulos, Kamel A. Abd-Elsalam, Andrea L. Aerts, Ali H. Bahkali, Henriek G. Beenen, Pranav Chettri, Murray P. Cox, Erwin Datema, Ronald P. De Vries, Braham Dhillon, Austen R. Ganley, Scott A. Griffiths, Yanan Guo, Richard C. Hamelin, Bernard Henrissat, M Shahjahan Kabir, Mansoor Karimi Jashni, Gert Kema, Sylvia Klaubauf, Alla Lapidus, Anthony Levasseur, Erika Lindquist, Rahim Mehrabi, Robin A. Ohm, Timothy J. Owen, Asaf Salamov, Arne Schwelm, Elio Schijlen, Hui Sun, Harrold A. Van Den Burg, Roeland C.H.J. Van Ham, Shuguang Zhang, Stephen B. Goodwin, Igor V. Grigoriev, Jérôme Collemare, Rosie E. Bradshaw

Department of Botany and Plant Pathology Faculty Publications

We sequenced and compared the genomes of the Dothideomycete fungal plant pathogensCladosporium fulvum (Cfu) (syn. Passalora fulva) and Dothistroma septosporum (Dse) that are closely related phylogenetically, but have different lifestyles and hosts. Although both fungi grow extracellularly in close contact with host mesophyll cells, Cfu is a biotroph infecting tomato, while Dse is a hemibiotroph infecting pine. The genomes of these fungi have a similar set of genes (70% of gene content in both genomes are homologs), but differ significantly in size (Cfu >61.1-Mb; Dse 31.2-Mb), which is mainly due to the difference in repeat content (47.2% …

Similarities Between Line Fishing And Baited Stereo-Video Estimations Of Length-Frequency: Novel Application Of Kernel Density Estimates, Timothy J. Langlois, Benjamin R. Fitzpatrick, David V. Fairclough, Corey B. Wakefield, Sybrand Alexander Hesp, Dianne L. Mclean, Euan S. Harvey, Jessica J. Meeuwig

Fisheries Research Articles

Age structure data is essential for single species stock assessments but length-frequency data can provide complementary information. In south-western Australia, the majority of these data for exploited species are derived from line caught fish. However, baited remote underwater stereo-video systems (stereo-BRUVS) surveys have also been found to provide accurate length measurements. Given that line fishing tends to be biased towards larger fish, we predicted that, stereo-BRUVS would yield length-frequency data with a smaller mean length and skewed towards smaller fish than that collected by fisheries-independent line fishing. To assess the biases and selectivity of stereo-BRUVS and line fishing we compared …

The Cowl - V.77 - N.11 - Nov 29, 2012

The Cowl

The Cowl - student newspaper of Providence College. Vol 77 - No. 11 - November 29, 2012. 28 pages.

Investigating A Model For Fetal Alcohol Damage In Caenorhabditis Elegans, Lindsay Kondo

Theses and Dissertations

Alcohol use and abuse has many harmful effects, especially to children exposed prenatally, including fetal alcohol spectrum disorders (FASDs). The disabilities due to fetal alcohol exposure continue throughout life and cause major financial burdens to society. The molecular mechanisms underlying FASDs are not well understood. We have taken a genetic approach to characterize ethanol’s effect on changing a discrete cell fate decision during embryogenesis in the nematode, Caenorhabditis elegans (C. elegans). Our preliminary data suggest that ethanol can affect the development of AWC neurons, a pair of olfactory neurons in C. elegans. We suggest that lipids can protect AWC neurons …

The Eastern Echo, November 29, 2012, Eastern Michigan University

EMU Student Newspaper: The Normal News & The Eastern Echo

No abstract provided.

The Eastern Echo, November 29, 2012, Eastern Michigan University

EMU Student Newspaper: The Normal News & The Eastern Echo

No abstract provided.

The Eastern Echo, November 29, 2012, Eastern Michigan University

EMU Student Newspaper: The Normal News & The Eastern Echo

No abstract provided.

Lanthorn, Vol. 47, No. 29, November 29, 2012, Grand Valley State University

Volume 47, July 2, 2012 - June 3, 2013

Lanthorn is Grand Valley State's student newspaper, published from 1968 to the present.

November 29, 2012, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

Necrostatin-1 Analogues: Critical Issues On The Specificity, Activity And In Vivo Use In Experimental Disease Models., N Takahashi, L Duprez, S Grootjans, A Cauwels, W Nerinckx, J B Duhadaway, V Goossens, R Roelandt, F Van Hauwermeiren, C Libert, W Declercq, N Callewaert, G C Prendergast, A Degterev, J Yuan, P Vandenabeele

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Necrostatin-1 (Nec-1) is widely used in disease models to examine the contribution of receptor-interacting protein kinase (RIPK) 1 in cell death and inflammation. We studied three Nec-1 analogs: Nec-1, the active inhibitor of RIPK1, Nec-1 inactive (Nec-1i), its inactive variant, and Nec-1 stable (Nec-1s), its more stable variant. We report that Nec-1 is identical to methyl-thiohydantoin-tryptophan, an inhibitor of the potent immunomodulatory enzyme indoleamine 2,3-dioxygenase (IDO). Both Nec-1 and Nec-1i inhibited human IDO, but Nec-1s did not, as predicted by molecular modeling. Therefore, Nec-1s is a more specific RIPK1 inhibitor lacking the IDO-targeting effect. Next, although Nec-1i was ∼100 × …

The Relationship Of Food And Academic Performance: A Preliminary Examination Of The Factors Of Nutritional Neuroscience, Malnutrition, And Diet Adequacy, Allison Woodhouse, Mark A. Lamport, Ph.D.

Christian Perspectives in Education

This article examines the extent of food’s impact on children’s academic achievement. The purpose of this study is to summarize existing research concerning the food-learning correlation and to synthesize studies regarding nutritional needs of the brain, malnutrition during development, and overall diet quality as related to academic achievement. Data finds a fundamental link between nutrition and cognition. Results suggest to the extent the brains of many United States schoolchildren do not receive the nutrients needed for optimal cognition, that academic performance may be consequentially reduced. Finally, a discussion of related learning theory and current debate, and practical implications for educational …

Biology Faculty Member's Article On Exotic Plants Appears In Ecology Letters, Winthrop University

Winthrop News 2012

• In his paper, Matt Heard notes that there has been little experimental fieldwork conducted to determine what factors allows native and exotic plants to live side by side.
• While there have been many potential explanations tossed out, it turns out that just being different is the main reason that they can actually coexist together.

The Cord (November 28, 2012)

The Cord

No abstract provided.

The Good 5 Cent Cigar (11/28/2012), University Of Rhode Island

The Good 5 Cent Cigar (Student Newspaper Archives)

This is a digitized, downloadable version of the University of Rhode Island school newspaper.

Murray Ledger And Times, November 28, 2012, Murray Ledger And Times

The Murray Ledger & Times

No abstract provided.

2012 November 28 - Undergraduate Curriculum Council Minutes, Undergraduate Curriculum Council, East Tennessee State University

Undergraduate Curriculum Council Minutes

No abstract provided.

Global Trophic Position Comparison Of Two Dominant Mesopelagic Fish Families (Myctophidae, Stomiidae) Using Amino Acid Nitrogen Isotopic Analyses, C. Anela Choy, Peter C. Davison, Jeffrey C. Drazen, Adrian Flynn, Elizabeth J. Gier, Joel C. Hoffman, Jennifer P. Mcclain-Counts, Todd W. Miller, Brian N. Popp, Steve W. Ross, Tracey Sutton

Marine & Environmental Sciences Faculty Articles

The δ15N values of organisms are commonly used across diverse ecosystems to estimate trophic position and infer trophic connectivity. We undertook a novel cross-basin comparison of trophic position in two ecologically well-characterized and different groups of dominant mid-water fish consumers using amino acid nitrogen isotope compositions. We found that trophic positions estimated from the δ15N values of individual amino acids are nearly uniform within both families of these fishes across five global regions despite great variability in bulk tissue δ15N values. Regional differences in the δ15N values of phenylalanine confirmed that bulk tissue δ15N values reflect region-specific water mass biogeochemistry …

Adapting To Climate Change On Western Public Lands: Addressing The Ecological Effects Of Domestic, Wild, And Feral Ungulates, Dominick A. Dellasala, Jonathan J. Rhodes, James R. Karr, Mary H. O'Brien, Thomas L. Fleischner, Debra L. Donahue, Robert L. Beschta, Cindy Deacon Williams

Faculty Articles

Climate change affects public land ecosystems and services throughout the American West and these effects are projected to intensify Even if greenhouse gas emissions are reduced adaptation strategies for public lands are needed to reduce anthropogenic stressors of terrestrial and aquatic ecosystems and to help native species and ecosystems survive in an altered environment Historical and contemporary livestock production ' the most widespread and longrunning commercial use of public lands ' can alter vegetation soils hydrology and wildlife species composition and abundances in ways that exacerbate the effects of climate change on these resources Excess abundance of native ungulates eg …

Pharmacokinetics And Brain Uptake In The Rhesus Monkey Of A Fusion Protein Of Arylsulfatase A And A Monoclonal Antibody Against The Human Insulin Receptor, Ruben J. Boado, Jeff Zhiqiang Lu, Eric Ka-Wai Hui, Rachita K. Sumbria, William M. Pardridge

Pharmacy Faculty Articles and Research

Metachromatic leukodystrophy (MLD) is a lysosomal storage disorder of the brain caused by mutations in the gene encoding the lysosomal sulfatase, arylsulfatase A (ASA). It is not possible to treat the brain in MLD with recombinant ASA, because the enzyme does not cross the blood-brain barrier (BBB). In the present investigation, a BBB-penetrating IgG-ASA fusion protein is engineered and expressed, where the ASA monomer is fused to the carboxyl terminus of each heavy chain of an engineered monoclonal antibody (MAb) against the human insulin receptor (HIR). The HIRMAb crosses the BBB via receptor-mediated transport on the endogenous BBB insulin receptor, …