Digital Commons Network^™

Clinical And Translation Research Day, The Rockefeller University

Posters

The Rockefeller University Hospital hosted Clinical and Translation Research Day on September 20th, 2012

Into The Bush, Unh Communications And Public Affairs

UNH Today Archive

No abstract provided.

Metabolic Effects Of Darunavir/Ritonavir Versus Atazanavir/Ritonavir In Treatment-Naive, Hiv Type 1-Infected Subjects Over 48 Weeks, Judith A. Aberg, Pablo Tebas, Edgar Turner Overton, Samir K. Gupta, Paul E. Sax, Alan Landay, Ron Falcon, Robert Ryan, Guy De La Rosa

Open Access Publications

No abstract provided.

September 20, 2012 Grove Edition, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

The Good 5 Cent Cigar (9/19/2012), University Of Rhode Island

The Good 5 Cent Cigar (Student Newspaper Archives)

This is a digitized, downloadable version of the University of Rhode Island school newspaper.

Gpsa Legislative Steering Committee Meeting, 9/18/2012, Graduate And Professional Student Association

GPSA Meeting Agendas and Minutes

No abstract provided.

Ultraviolet Radiation–Induced Cataract In Mice: The Effect Of Age And The Potential Biochemical Mechanism, Jie Zhang, Hong Yan, Stefan Lofgren, Xiaoli Tian, Marjorie F. Lou

School of Veterinary and Biomedical Sciences: Faculty Publications

PURPOSE. To study the effect of age on the morphologic and biochemical alterations induced by in vivo exposure of ultraviolet radiation (UV).

METHODS. Young and old C57BL/6 mice were exposed to broadband UVBþUVA and euthanized after 2 days. Another batch of UV-exposed young mice was monitored for changes after 1, 2, 4, and 8 days. Age-matched nonexposed mice served as controls. Lens changes were documented in vivo by slit-lamp biomicroscopy and dark field microscopy photographs ex vivo. Lens homogenates were analyzed for glutathione (GSH) level, and the activities of thioredoxin (Trx), thioltransferase (TTase), and glyceraldehyde-3-phosphate dehydrogenase (G3PD). Glutathionylated lens proteins …

What Is The Predictive Power Of The Colobine Protein-To-Fiber Model And Its Conservation Value?, Jan F. Gogarten, Melissa Guzman, Colin A. Chapman, Aerin L. Jacob, Patrick A. Omeja, Jessica Rothman

Publications and Research

Predicting variation in animal abundance across time and space has proven very difficult; however, a model exists to predict the biomass of small folivorous primates that has considerable correlative support. This model suggests that the protein-to-fiber ratio of leaves in a habitat can predict folivore biomass. Here we present an experimental test of this protein-to-fiber model to assess if the number of infant monkeys per female and group size can be predicted based on the leaf chemistry of a habitat. We expected regenerating forest in Kibale National Park, Uganda to have leaves with higher concentrations of crude protein and lower …

Evaluating Short-Term Patient Outcomes After Hiv Care Interventions In A Low Resource Setting: Preparing For An Hiv Vaccine Trial Site In Bamako, Mali, Z. Koty, A. Bicki, Y. Koné, L. Diarra, K. Tounkara, F. Siby Diallo, L. Levitz, B. Aboubacar, M. Rochas, S. Dao, Anne S. De Groot

Institute for Immunology and Informatics Faculty Publications

Poster Presentation From AIDS Vaccine 2012 Boston, MA, USA. 9-12 September 2012

Commonwealth Times 2012-09-13

Commonwealth Times, 1969-

No abstract provided.

Sandspur, Vol 119, No 02, September 13, 2012, Rollins College

The Rollins Sandspur

Rollins College student newspaper, written by the students and published at Rollins College. The Sandspur started as a literary journal.

Building A Sustainable Nurse-Managed Clinic System Through Faculty Practice And Technology Integration, Julie Cowan Novak

International Nursing Research Congress (INRC)

Scope/Significance: Over the past four years, the UTHSCSA School of Nursing has developed, implemented, and evaluated a viable alternative to the failing, mismanaged US healthcare delivery system. Two nurse-managed clinics are currently in operation with two in development. Client visits exceeded 7,000 in 2011. The clinics are sustained through a mosaic of support from a variety of funding sources including private, state and federal insurance, billing, and grants. Faculty and students develop an integrated model of discovery, learning and engagement focused on evidence-based health promotion/disease prevention, client, family, and community education, acute, episodic illness care, management of stable chronic conditions …

"Whatever It Takes:" A Photovoice Exploration Of Isolated Allogenic Hematopoietic Stem Cell Transplantation Patients, Caroline E. Brown, Kathryn R. Siebert, Ellen R. Carr

International Nursing Research Congress (INRC)

Purpose: Protective isolation is a common practice among hematopoietic stem cell transplantation (HSCT) patients. Psychological intolerance of protective isolation was identified as a problem leading to discontinuation of isolation in between 2-42% of patients in a recent systematic review. The purpose of this qualitative study was to explore isolated HCST patients' perceptions of isolation and elicit suggestions for interventions to mediate the experience of isolation.

Methods: Participants were recruited from isolated patients on the inpatient Bone Marrow Transplantation (BMT) unit after at least one week of isolation. In-depth interview was the primary research method used; in addition photo voice was …

September 12, 2012, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

The Effect Of Tenofovir On Vitamin D Metabolism In Hiv-Infected Adults Is Dependent On Sex And Ethnicity, Karen Klassen, Adrian R. Martineau, Robert J. Wilkinson, Graham Cooke, Alan P. Courtney, Mary Hickson

School of Health Professions

No abstract provided.

A Global Health Internship For Bsn Students, Phyllis Shanley Hansell

International Nursing Research Congress (INRC)

Purpose: The purpose of this project was to implement a project to advance the global perspective for nursing education and research. Methods: International partnership exchange opportunities were made available to undergraduate students on a competitive. opportunities included exchange practicum experiences with a variety of international educational exchange opportunities that were available at a variety of international settings. Students chose from among partnership opportunities in Copenhagen, Denmark; Petoria, South Africa; Galway, Ireland; Wuhan, China; the Philippines and Macau, China. Students who met the criteria received full support for airfare and support for their designated project. Students selected application for the program …

2012 Proceedings Of The 19th Annual Summer Research Symposium, College Of The Holy Cross

Summer Research Program

The 2012 Undergraduate Summer Research Symposium, now in its 19th year, is a college-wide event that brings together faculty and students from all disciplines at Holy Cross and provides an opportunity to celebrate their accomplishments over the summer of 2012. This program lists participating students, the faculty with whom they worked and their projects.

September 7, 2012 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

Human Cytomegalovirus Induces Tlr4 Signaling Components In Monocytes Altering Tirap, Tram And Downstream Interferon-Beta And Tnf-Alpha Expression., Kok-Hooi Yew, Cory Carpenter, R Scott Duncan, Christopher J. Harrison

Manuscripts, Articles, Book Chapters and Other Papers

Using TLR pathways, primary human cytomegalovirus (HCMV) induces innate responses including the production of inflammatory cytokines. Mounting evidence suggests that LPS recognition by TLR4/MD2/CD14 results in differential utilization of TIRAP-TRAF6 and TRAM-TRIF signaling, thereby leading to transcriptional activation of various cytokine genes. However, relative roles of the TLR4/MD2/CD14 complex and its adaptor proteins TIRAP and TRAM involved in regulating monocyte responses to HCMV are incomplete. Here, we provided evidence supporting the notion that the TLR4/MD2/CD14 complex contributes notably to HCMV-induced signaling and subsequent cytokine production in monocytes. In particular, induction of both IL-6 and IL-8 is associated with elevated TIRAP …

Human Cytomegalovirus Induces Tlr4 Signaling Components In Monocytes Altering Tirap, Tram And Downstream Interferon-Beta And Tnf-Alpha Expression, Kok-Hooi Yew, Cory Carpenter, R. Scott Duncan, Christopher J. Harrison

Student Publications

Using TLR pathways, primary human cytomegalovirus (HCMV) induces innate responses including the production of inflammatory cytokines. Mounting evidence suggests that LPS recognition by TLR4/MD2/CD14 results in differential utilization of TIRAP-TRAF6 and TRAM-TRIF signaling, thereby leading to transcriptional activation of various cytokine genes. However, relative roles of the TLR4/MD2/CD14 complex and its adaptor proteins TIRAP and TRAM involved in regulating monocyte responses to HCMV are incomplete. Here, we provided evidence supporting the notion that the TLR4/MD2/CD14 complex contributes notably to HCMV-induced signaling and subsequent cytokine production in monocytes. In particular, induction of both IL-6 and IL-8 is associated with elevated TIRAP …

Rag1-/- Mutant Zebrafish Demonstrate Specific Protection Following Bacterial Re-Exposure., Claudia Hohn, Lora Petrie-Hanson

CVM Publications

BACKGROUND: Recombination activation gene 1 deficient (rag1(-/-)) mutant zebrafish have a reduced lymphocyte-like cell population that lacks functional B and T lymphocytes of the acquired immune system, but includes Natural Killer (NK)-like cells and Non-specific cytotoxic cells (NCC) of the innate immune system. The innate immune system is thought to lack the adaptive characteristics of an acquired immune system that provide enhanced protection to a second exposure of the same pathogen. It has been shown that NK cells have the ability to mediate adaptive immunity to chemical haptens and cytomegalovirus in murine models. In this study we evaluated the ability …

Case Study Of Indoor Air Quality Of Health Care Facilities And Hospitals In Malaysia / Phuah Kok Sun, Kok Sun Phuah

Student Works (2010-2019)

Hospitals and healthcare facilities are buildings that require proper design for diverse environment due to their nature. The comfort of occupants and the spread of germs should be consider in the design of such facilities. Airborne diseases have become a serious concern after the spread of influenza H1N1 and Severe Acture Respiratory Syndrome (SARS) viruses. Healthcare facilities, particularly those built in the past, do not consider air as the transport medium for infectious diseases. Most of the recent studies in indoor air control revolve around specialized environments such as isolation rooms and operating theatres. This dissertation studies the indoor air …

Leveraging The Dialectical Theory In Case Study Analysis: Genzyme's Ethical Dilemma, Andrei Duta

The Journal of Business, Entrepreneurship & the Law

This paper provides the theoretical framework for a case study that I share with students in my courses. The dialectical theory is used to analyze ethical conundrums pertaining to Genzyme, a successful bio-tech corporation based in Boston, Massachusetts that manufactures treatments for serious diseases such as kidney problems, immune diseases, and cancer. We discuss questions such as: is Genzyme acting unethically when averaging extremely high profit margins on drugs for rare diseases? Is the company taking advantage of the lack of pharmaceutical choices that patients have when addressing their ailments? The dialectical theory provides the framework and vocabulary for discussing, …

With No West Nile Vaccine In Sight, Self-Protection Is Key, Jim Bakken

Browse All News

No abstract provided.

Organization Of The Streptococcal Exportal And Its Interaction With Cationic Antimicrobial Peptides, Luis Alberto Vega

All Theses and Dissertations (ETDs)

Streptococcus pyogenes and other Gram-positive pathogens are highly dependent on secreted virulence proteins for their ability to colonize a host and evade the immune effectors that act on pathogens to prevent this. Unlike eukaryotes and Gram-negative bacteria, all Gram-positive pathogens lack a cellular compartment dedicated to folding and processing secreted proteins once they have been translocated across the cytoplasmic membrane. S. pyogenes and other Gram-positive organisms overcome this challenge by clustering the secretory translocons at a defined anionic lipid microdomain of the cytoplasmic membrane that is enriched for accessory factors needed for protein biogenesis, referred to as the ExPortal. The …

Emerging Burden Of Frail Young And Elderly Persons In Oman : For Whom The Bell Tolls?, Hamed Al-Sinawi, Mohammed Al-Alawi, Rehab Al-Harrasi, Ahmed, Mohammed Al-Shafaee, Samir Al-Adawi

Sultan Qaboos University Medical Journal

Recent improvements in health and an increased standard of living in Oman have led to a reduction in environment-related and infectious diseases. Now the country is experiencing an epidemiological transition characterised by a baby boom, youth bulge and increasing longevity. Common wisdom would therefore suggest that Omanis will suffer less ill health. However, a survey of literature suggests that chronic non-communicable diseases are unexpectedly becoming common. This is possibly fuelled by some socio-cultural patterns specific to Oman, as well as the shortcomings of the ‘miracle’ of health and rapid modernisation. Unfortunately, such new diseases do not spare younger people; a …

First International Nursing Conference Oman Innovations In Nursing Education And Practice Leading To Quality Care Sultan Qaboos University, Oman, 28–29th November 2011, Sultan Qaboos University

Sultan Qaboos University Medical Journal

No abstract provided.

Ada News - 09/03/2012, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

The Causes, Treatment, And Outcome Of Acute Heart Failure In 1006 Africans From 9 Countries, Albertino Damasceno, Bongani M. Mayosi, Mahmoud Sani, Okechukwu S. Ogah, Charles Mondo, Dike Ojji, Anastase Dzudie, Charles Kouam Kouam, Ahmed Suliman, Neshaad Schrueder, Gerald Yonga, Serigne Abdou Ba, Fikru Maru, Bekele Alemayehu, Christopher Edwards, Beth A. Davison, Gad Cotter, Karen Sliwa

Internal Medicine, East Africa

Background: Acute heart failure (AHF) in sub-Saharan Africa has not been well characterized. Therefore,wesought to describe the characteristics, treatment, and outcomes of patients admitted with AHF in sub-Saharan Africa.

Methods: The Sub-Saharan Africa Survey of Heart Failure (THESUS–HF) was a prospective, multicenter, observational survey of patients with AHF admitted to 12 university hospitals in 9 countries. Among patients presenting with AHF, we determined the causes, treatment, and outcomes during 6 months of follow-up.

Results: From July 1, 2007, to June 30, 2010, we enrolled 1006 patients presenting with AHF. Mean (SD) age was 52.3 (18.3) years, 511 (50.8%) were women, …

Occurrence Of Pneumococcal Meningitis In Iraq, Huda Z. Al-Banae, Khalid A. Habib, Kifah A. Al-Khurki

Baghdad Science Journal

This study focuses on the relative frequency of Streptococcus pneumoniae in children with culture-proven bacterial meningitis. The epidemiology has been investigated with clinical and laboratory findings in The Central Public Health Laboratory, Iraq from April to September, 2010. From (138) samples , (55) cases (39.85 %) were diagnosed by physician as bacterial meningitis, (23) cases (16.66 %) as viral menginitis , (18) cases (13.04 %) as different medical cases (e.g febrile convulsion , meningoencephalitis , epilepsy …etc) and (42) cases (30.43 %) as unidentified medical cases. For bacterial meningitis S.pneumoniae was isolated from (10) cases (18.18 %) only. The median …