Digital Commons Network^™

Competition Agency Design: What's On The Menu?, William E. Kovacic, David A. Hyman

GW Law Faculty Publications & Other Works

In recent years the United Kingdom and various other countries have decided to restructure the institutions responsible for enforcing competition laws. How should a nation choose among myriad alternative arrangements? This paper lays out nine major institutional choices that governments must address in designing the implementation mechanism for a competition law. The paper discusses tradeoffs associated with each choice and examines interdependencies among different design elements. In doing so, the paper offers a structured framework that countries can use in forming new competition systems or altering existing institutional arrangements.

Pain Relief In Older Adults Following Static Contractions Is Not Task-Dependent, Kathy J. Lemley, Breanna Drewek, Lauren Miller, Sandra K. Hunter, Marie K. Hoeger Bement

Physical Therapy Faculty Research and Publications

Pain complaints increase with age. Exercise is frequently utilized for pain relief but the optimal exercise prescription to relieve pain is not clear. Following static contractions, young adults experience the greatest pain relief with low intensity, long duration contractions. The pain response to static contractions in older adults however is unknown.

PURPOSE : To compare pain reports in healthy older adults before and after static contractions of varying intensity and duration.

METHODS: Pain perception was assessed in 23 healthy older adults (11 men, 12 women; 72.0 ± 6.3 yrs) using a pressure pain device consisting of a 10 N force …

Why We Should Never Pay Down The National Debt, Neil H. Buchanan

GW Law Faculty Publications & Other Works

Calls either to balance the federal budget on an annual basis, or to pay down all or part of the national debt, are based on little more than uninformed intuitions that there is something inherently bad about borrowing money. We should not only ignore calls to balance the budget or to pay down the national debt, but we should engage in a responsible plan to increase the national debt each year. Only by issuing debt to lubricate the financial system, and to support the economy’s healthy growth, can we guarantee a prosperous future for current and future citizens of the …

Learning Sparse Representations For Fruit Fly Gene Expression Pattern Image Annotation And Retreival, Lei Yuan, Alexander Woodard, Shuiwang Ji, Yuan Jiang, Zhi-Hua Zhou, Sudhir Kumar, Jieping Ye

Computer Science Faculty Publications

Background: Fruit fly embryogenesis is one of the best understood animal development systems, and the spatiotemporal gene expression dynamics in this process are captured by digital images. Analysis of these high-throughput images will provide novel insights into the functions, interactions, and networks of animal genes governing development. To facilitate comparative analysis, web-based interfaces have been developed to conduct image retrieval based on body part keywords and images. Currently, the keyword annotation of spatiotemporal gene expression patterns is conducted manually. However, this manual practice does not scale with the continuously expanding collection of images. In addition, existing image retrieval systems based …

Reassessing The Cultural Distance Between China And The United States As Perceived By Students From The Sino-American 1+2+1 Dual Degree Program, Cynthia Letts

EWU Masters Thesis Collection

"As a result of the exponential growth of international commerce and academic exchange between Mainland China and the United States, this thesis examines the present-day validity of those Chinese and American cultural characteristics, such as practices and values, historically understood as defining cultural differences. Using Babiker's Cultural Distance Index (Babiker, Cox, & Miller, 1980) questionnaire (an institutionally established instrument since 1980), 45 Mainland Chinese student-sojourners conveyed their perceptions of cultural differences found in daily living. Chinese participants identified many cultural attributes that still affect the migrant's perceptions of difference. These attributes are language, food, education costs, and leisure activities. Participants …

The Impact Of Black Swan (Cygnus Atratus) Grazing On The Seagrass Halophila Ovalis In The Lower Swan River Estuary, Gary Choney

Theses: Doctorates and Masters

Grazing is an important ecosystem process, influencing community structure and rates of ecosystem processes. Although grazing on seagrasses is generally considered to be minor in many temperate regions of the world, waterfowl are often considered significant grazers in temperate lagoons and estuaries. This study examined spatial and temporal variation in swan abundance, grazing pressure and the impact grazing has on seagrass. Little is known on how grazing rates vary on larger water bodies in the southern hemisphere at different times of year and whether temporal changes in grazing rates affect the ability of seagrasses to tolerate grazing. The plant response …

Prevalence Of Anguillicoloides Crassus And Growth Variation In Migrant Yellow-Phase American Eels Of The Upper Potomac River Drainage, Jl Zimmerman, Sa Welsh

Faculty & Staff Scholarship

No abstract provided.

Network Modeling Of Bvd Transmission, Mark Tinsley, Fraser I. Lewis, Franz Brulisauer

Faculty & Staff Scholarship

Endemic diseases of cattle, such as bovine viral diarrhea, have significant impact on production efficiency of food of animal origin with consequences for animal welfare and climate change reduction targets. Many modeling studies focus on the local scale, examining the on-farm dynamics of this infectious disease. However, insight into prevalence and control across a network of farms ultimately requires a network level approach. Here, we implement understanding of infection dynamics, gained through these detailed on-farm modeling studies, to produce a national scale model of bovine viral diarrhea virus transmission. The complex disease epidemiology and on-farm dynamics are approximated using SIS …

The Phosphodiesterase-4 Inhibitor Rolipram Reverses Aβ-Induced Cognitive Impairment And Neuroinflammatory And Apoptotic Responses In Rats, Chuang Wang, Xue-Mei Yang, Ye-Ye Zhuo, Heng Zhou, Huan-Bing Lin, Yu-Fang Cheng, Jiang-Ping Xu, Han-Ting Zhang

Faculty & Staff Scholarship

No abstract provided.

Forty Years Of Increasing Suicide Mortality In Poland: Undercounting Amidst A Hanging Epidemic?, Peter Höfer, Ian R H Rockett, Peeter Värnik, Elmar Etzersdorfer, Nestor D Kapusta

Faculty & Staff Scholarship

No abstract provided.

Mechanism Of Action Of A Novel Antifungal Compound, Amber Ward

Honors Theses

Opportunistic fungal infections have become problematic in recent years. There has been an emergence of new fungal pathogens, development of antifungal resistance, and increasing prevalence. In addition, toxicity, resistance, and lack of efficacy as a single agent limit the effectiveness of current antifungal drugs. Therefore, new drugs targeting new pathways are greatly needed. An analog derived from the marine natural product phloeodictine, analog PHL5-34A, was identified as having strong in vitro antifungal activity. In this study, its mechanism of action (MOA) was investigated in the model yeast, Saccharomyces cerevisiae. This study made use of a collection of 166 yeast mutants …

Working Towards A Solution To The Obesity Epidemic: A Marketer's Perspective, Elizabeth Ann Clippard

Honors Theses

The obesity epidemic is a social issue in that critics are quick to blame business and government for failing the consumers. The truth is that all three parties have failed each other by allowing such a cultural change to occur. The issue is similar to the tobacco public health crisis following the spike in lung cancer in the 1950s and 60s. The tobacco companies were blamed entirely for their unhealthy products and the government still spends millions today regulating their products. In order to improve upon this course of action, I believe that a more cooperative solution exists in order …

Angiotensin Ii As A Potential Regulator Of Inflammatory Cytokines In Inducing Hypertension In Systemic Lupus Erythematosus, Khush Singh Aujla

Honors Theses

The disease Systemic Lupus Erythematosus is a chronic inflammatory, autoimmune disorder that primarily affects women during their reproductive years. Women with SLE are at a greater risk of developing hypertension, which increases their risk of mortality from a cardiac related event. A proposed mechanism for SLE hypertension suggests that inflammation in the kidneys causes renal dysfunction, presumably resulting in less water excretion, increased plasma volume, and thus high blood pressure. This experiment tests the hypothesis that the T-cells from a mouse model of SLE hyper secrete the inflammatory cytokines IL-17, IL-10, and DFN- y, and are more sensitive to the …

An Investigation Of Host Variation In The Host-Parasite Interaction Of Sciurus Carolinensis And Cuterebra Emasculator, Miles Moore Debardeleben

Honors Theses

Within a population, susceptibility to parasitism may vary. Individuals possessing certain intrinsic or extrinsic traits are often more likely to be parasitized than individuals within that population that do not possess those certain traits. As a result, parasites can have profound effects of the population dynamics of theirs hosts. Much research has been done on the host-parasite interaction of the eastern grey squirrel {Sciurus caroUnensis) and the tree squirrel hot fly {Cuterebra emasculator). However, relatively little research has been done on host susceptibility to this parasite. Knowing that bot flies can lower reproductive success, reduce fitness, and cause death of …

Investigation Of Brown Recluse (Loxosceles Reclusa) And Black Widow (Latrodectus Mactans) Spider-Bite Diagnoses By Medical Professionals Across Three Regions Of Mississippi, Hillary Michelle Howell

Honors Theses

During 4 weeks of the spring of 2011 and 5 weeks of the fall of 2011, interviews were conducted with medical professionals practicing in Mississippi regarding the diagnosis of brown recluse {Loxosceles reclusa) and black widow {Latrodectus mactans) spider bites. During the spring, a total of 19 interviews were held with emergency room physicians and dermatologists practicing in urban and rural, non-medically underserved areas of Mississippi. The participants varied in their location of practice across the 3 regions of Mississippi. During the fall, a total of 5 interviews were conducted with nurse practitioners and one pediatrician practicing in rural, medically …

Strict Liability In Negligence, Kenneth S. Abraham

DePaul Law Review

No abstract provided.

Reflections On Tort And The Administrative State, Robert L. Rabin

DePaul Law Review

No abstract provided.

An Alternative Explanation For No-Fault's Demise, Nora Freeman Engstrom

DePaul Law Review

No abstract provided.

Professor Rabin And The Administrative State , Peter H. Schuck

DePaul Law Review

No abstract provided.

Pure Confusion: Should Pure Licensors Share The Products Liability Of Manufacturers And Sellers Of Dangerously Defective Products?, Stephen C. Jarvis

DePaul Law Review

No abstract provided.

The Federal Employers' Liability Act: Sense And Nonsense About Causation, Michael D. Green

DePaul Law Review

No abstract provided.

Against Categorical Preemption: Vaccines And The Compensation Piece Of The Preemption Puzzle, Catherine M. Sharkey

DePaul Law Review

No abstract provided.

Why No Duty?, Stephen D. Sugarman

DePaul Law Review

No abstract provided.

Whom Must The Clergy Protect: The Interests Of At-Risk Children In Conflict With Clergy-Penitent Privilege, Paul Winters

DePaul Law Review

No abstract provided.

Angiotensin Ii: A Potential Link Between Inflammation And Hypertension In Sle, Khush Singh Aujla

Honors Theses

The disease Systemic Lupus Erythematosus is a chronic inflammatory, autoimmune disorder that primarily affects women during their reproductive years. Women with SLE are at a greater risk of developing hypertension, which increases their risk of mortality from a cardiac related event. A proposed mechanism for SLE hypertension suggests that inflammation in the kidneys causes renal dysfunction, presumably resulting in less water excretion, increased plasma volume, and thus high blood pressure. This experiment tests the hypothesis that the T-cells from a mouse model of SLE hyper secrete the inflammatory cytokines IL-17, IL-10, and IFN- y, and are more sensitive to the …

Defects In Acute Rsponses To Tlr4 In Btk-Deficient Mice Result In Impaired Dendritic Cell-Induced Ifn-Γ Production By Natural Killer Cells, Joan Ní Gabhann, Shaun Spence, Claire Wynne, Siobhán Smith, Jennifer C. Byrne, Barbara Coffey, Kevin Stacey, Adrien Kissenpfennig, James A. Johnston, Caroline A. Jefferies

Articles

This study defines a critical role for Btk in regulating TLR4-induced crosstalk between antigen presenting cells (APCs) and natural killer (NK) cells. Reduced levels of IL-12, IL- 18 and IFN-γ were observed in Btk-deficient mice and ex vivo generated macrophages and dendritic cells (DCs) following acute LPS administration, whilst enhanced IL-10 production was observed. In addition, upregulation of activation markers and antigen presentation molecules on APCs was also impaired in the absence of Btk. APCs, by virtue of their ability to produce IL-12 and IL-18, are strong inducers of NK-derived IFN-γ. Co-culture experiments demonstrate that Btk-deficient DCs were unable to …

Bi-Lateral Changes To Hippocampal Cholesterol Levels During Epileptogenesis And In Chronic Epilepsy Following Focal-Onset Status Epilepticus In Mice, Steve Meaney, Maura Heverin, Tobias Engel, Eva Jimenez-Mateosa, Reza Al-Aaudia, David Henshall

Articles

Brain cholesterol homeostasis has been shown to be disrupted in neurodegenerative conditions such as Alzheimer's and Huntington's diseases. Investigations in animal models of seizure-induced brain injury suggest that brain cholesterol levels are altered by prolonged seizures (status epilepticus) and are a feature of the pathophysiology of temporal lobe epilepsy. The present study measured hippocampal sterol levels in a model of unilateral hippocampal injury triggered by focal-onset status epilepticus, and in chronically epileptic mice. Status epilepticus was induced by intra-amygdala microinjection of kainic acid and ipsilateral and contralateral hippocampus analyzed. No significant changes were found for ipsilateral or contralateral hippocampal levels …

Point Of Care Diagnostics: Status And Future, Vladimir Gubala, Leanne Harris, Antonio J. Ricco, Ming X. Tan, David Williams

Articles

The most commonly used test for monitoring heparin therapy is the activated partial thromboplastin time (aPTT). The response of available aPTT reagents to heparin varies significantly. The aim of this study was to highlight the differences between aPTT reagents stored in a dried format to select the most suitable formulations to be used for the development of point-of-care diagnostic devices used for monitoring of unfractionated heparin dose response.

METHODS:

Ten reagents were analysed in terms of their performance in liquid and in dried form after storage for 24 h and 14 days. Performance was assessed by measurement of the clotting …

Eae/Ase Recommendations For Image Acquisition And Display Using Three-Dimensional Echocardiography., Roberto M. Lang, Luigi P. Badano, Wendy Tsang, David H. Adams, Eustachio Agricola, Thomas Buck, Francesco F. Faletra, Andreas Franke, Judy Hung, Leopoldo Pérez De Isla, Otto Kamp, Jaroslaw D. Kasprzak, Patrizio Lancellotti, Thomas H. Marwick, Marti L. Mcculloch, Mark J. Monaghan, Petros Nihoyannopoulos, Natesa G. Pandian, Patricia A. Pellikka, Mauro Pepi, David A. Roberson, Stanton K. Shernan, Girish S. Shirali, Lissa Sugeng, Folkert J. Ten Cate, Mani A. Vannan, Jose Luis Zamorano, William A. Zoghbi, American Society Of Echocardiography, European Association Of Echocardiography

Manuscripts, Articles, Book Chapters and Other Papers

No abstract provided.

Theism And Psychological Science: A Call For Rapprochement, Michael J. Vogel, Tyler A. Gerdin, Mark R. Mcminn

Faculty Publications - Doctor of Psychology (PsyD) Program

The authors offer two arguments for the inclusion of theism in natural science. First, an argument against excluding theism is offered. Though early roots of science promoted a view that it is a way to accumulate knowledge that is untainted by presuppositions and traditions, postmodern critiques call this into question. Scientists have sometimes rejected religion as a context-dependent, tradition-based way of knowing, yet science itself is also context-dependent and tradition-based. Second, an argument for including theism in psychological is offered. Theistic beliefs are relevant insofar as they are part of human experience for many, they represent a form of human …