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2012

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Incidental Findings In Genetic Research: A Vexing Challenge For Community Consent, Elana Brief, Jennifer Mackie, Judy Illes Jan 2012

Incidental Findings In Genetic Research: A Vexing Challenge For Community Consent, Elana Brief, Jennifer Mackie, Judy Illes

Minnesota Journal of Law, Science & Technology

No abstract provided.


Enforcing The Rights Of Human Sources To Informed Consent And Disclosures Of Incidental Findings From Biobanks And Researchers: State Mechanisms In Light Of Broad Regulatory Failure, Leili Fatehi, Ralph F. Hall Jan 2012

Enforcing The Rights Of Human Sources To Informed Consent And Disclosures Of Incidental Findings From Biobanks And Researchers: State Mechanisms In Light Of Broad Regulatory Failure, Leili Fatehi, Ralph F. Hall

Minnesota Journal of Law, Science & Technology

No abstract provided.


John Wiley & Sons, Inc. V. Kirtsaeng: The Uncertain Future Of The First-Sale Doctrine, Benjamin Hamborg Jan 2012

John Wiley & Sons, Inc. V. Kirtsaeng: The Uncertain Future Of The First-Sale Doctrine, Benjamin Hamborg

Minnesota Journal of Law, Science & Technology

No abstract provided.


Rethinking Off-Label Regulation In The Wake Of Sorrell V. Ims Health: Can State Involvement Compensate For Waning Fda Authority To Curb Commercial Free Speech?, Ashley A. Zborowsky Jan 2012

Rethinking Off-Label Regulation In The Wake Of Sorrell V. Ims Health: Can State Involvement Compensate For Waning Fda Authority To Curb Commercial Free Speech?, Ashley A. Zborowsky

Minnesota Journal of Law, Science & Technology

No abstract provided.


Memphis Taxpayer Blues: An Economic Analysis Of The Memphis Pilot Program, Norman Lee Morris Iii Jan 2012

Memphis Taxpayer Blues: An Economic Analysis Of The Memphis Pilot Program, Norman Lee Morris Iii

Honors Theses

This thesis evaluates the economic impact of targeted tax cuts in Tennessee. Specifically, I examine the Payment-In-Lieu-Of-Taxes (PILOT) Program in Memphis, TN Using economic data supplied from the Federal Reserve Bank of St. Louis s Federal Economic Data and the Bureau of Labor Statistics, I consider the effectiveness of the program’s ability to improve economic conditions in Memphis, TN. The merits of a targeted tax cut program such as PILOT are often touted as the total number of jobs created and amount of dollars invested into the community. However, this method of counting the total number of jobs created overstates …


Antibiotic Resistance Of Bacteria Isolated From Leafy Green Salad Vegetables, Brooke Elizabeth Reynolds Jan 2012

Antibiotic Resistance Of Bacteria Isolated From Leafy Green Salad Vegetables, Brooke Elizabeth Reynolds

Honors Theses

Bacterial isolates obtained from samples of five varieties of leafy green vegetables were tested for resistance to four different antibiotics: ampicillin. erythromycin, streptomycin, and tetracycline. Isolates were separated based on media type (TSA vs. R2A media), sterilization techniques (surface sterilized vs. unsterilized). cultivation methods (conventional vs. organic), and specific lettuce type origins. Resistances were tested using a microscale broth culture technique, which allowed for growth of isolates in the presence of different concentrations of antibiotic. Antibiotic resistance was observed in all groups of isolates, although levels of resistance varied depending on the particular isolate and the antibiotic tested. Isolates were …


On The Fringes Of Peripheries: A Comparison Of The Working-Class Representations Of Larry Brown And Irvine Welsh, Christopher Paul Patterson Jan 2012

On The Fringes Of Peripheries: A Comparison Of The Working-Class Representations Of Larry Brown And Irvine Welsh, Christopher Paul Patterson

Honors Theses

In this thesis, I compare the fiction of Mississippi author Larry Brown and Scottish author Irvine Welsh, specifically in how they represent their respective regions’ working classes. The project concerns the genre of working-class fiction in both the American South and Scotland, as well as the general fields of Southern and Scottish contemporary fiction. The groundwork for this thesis began when I read Welsh’s Trainspotting while studying at the University of Edinburgh in Scotland during the spring of 2011.1 wanted to explore why Welsh’s working-class representations felt so similar to the Southern fiction I read at the University of Mississippi, …


Near Infrared Spectroscopy Describes Physiologic Payback Associated With Excess Postexercise Oxygen Consumption In Healthy Controls And Children With Complex Congenital Heart Disease, Michael J. Danduran, J. E. Dixon, Rohit P. Rao Jan 2012

Near Infrared Spectroscopy Describes Physiologic Payback Associated With Excess Postexercise Oxygen Consumption In Healthy Controls And Children With Complex Congenital Heart Disease, Michael J. Danduran, J. E. Dixon, Rohit P. Rao

Exercise Science Faculty Research and Publications

Exercise creates a physiologic burden with recovery from such effort crucial to adaptation. Excess postexercise oxygen consumption (EPOC) refers to the body’s increased metabolic need after work. This investigation was designed to determine the role of near infrared spectroscopy (NIRS) in the description of exercise recovery in healthy controls (NL) and children with congenital heart disease (CHD). Subjects were recruited with exercise testing performed to exhaustion. Exercise time (EXT), heart rate (HR), and oxygen consumption (VO2) were measured. Four-site NIRS (brain, kidney, deltoid, and vastus lateralis) were measured during exercise and into recovery to establish trends. Fifty individuals …


Effects Of Homosynaptic Depression On Spectral Properties Of H-Reflex Recordings, Kristof Kipp, Samuel T. Johnson, Mark A. Hoffman Jan 2012

Effects Of Homosynaptic Depression On Spectral Properties Of H-Reflex Recordings, Kristof Kipp, Samuel T. Johnson, Mark A. Hoffman

Exercise Science Faculty Research and Publications

The purpose of this study was to determine the effects of homosynaptic depression (HD) on spectral properties of the soleus (SOL) H-reflex. Paired stimulations, separated by 100 ms, were used to elicit an unconditioned and conditioned H-reflex in the SOL muscle of 20 participants during quiet standing. Wavelet and principal component analyses were used to analyze features of the time-varying spectral properties of the unconditioned and conditioned H-reflex. The effects of HD on spectral properties of the H-reflex signal were quantified by comparing extracted principal component scores. The analysis extracted two principal components: one associated with the intensity of the …


Behavioral Economics: Implications For Regulatory Behavior, William E. Kovacic, James C. Cooper Jan 2012

Behavioral Economics: Implications For Regulatory Behavior, William E. Kovacic, James C. Cooper

GW Law Faculty Publications & Other Works

Behavioral economics (BE) examines the implications for decision-making when actors suffer from biases documented in the psychological literature. This article considers how such biases affect regulatory decisions. The article posits a simple model of a regulator who serves as an agent to a political overseer. The regulator chooses a policy that accounts for the rewards she receives from the political overseer — whose optimal policy is assumed to maximize short-run outputs that garner political support, rather than long-term welfare outcomes — and the weight the regulator puts on the optimal long run policy. Flawed heuristics and myopia are likely to …


Competition Agency Design: What's On The Menu?, William E. Kovacic, David A. Hyman Jan 2012

Competition Agency Design: What's On The Menu?, William E. Kovacic, David A. Hyman

GW Law Faculty Publications & Other Works

In recent years the United Kingdom and various other countries have decided to restructure the institutions responsible for enforcing competition laws. How should a nation choose among myriad alternative arrangements? This paper lays out nine major institutional choices that governments must address in designing the implementation mechanism for a competition law. The paper discusses tradeoffs associated with each choice and examines interdependencies among different design elements. In doing so, the paper offers a structured framework that countries can use in forming new competition systems or altering existing institutional arrangements.


Pain Relief In Older Adults Following Static Contractions Is Not Task-Dependent, Kathy J. Lemley, Breanna Drewek, Lauren Miller, Sandra K. Hunter, Marie K. Hoeger Bement Jan 2012

Pain Relief In Older Adults Following Static Contractions Is Not Task-Dependent, Kathy J. Lemley, Breanna Drewek, Lauren Miller, Sandra K. Hunter, Marie K. Hoeger Bement

Physical Therapy Faculty Research and Publications

Pain complaints increase with age. Exercise is frequently utilized for pain relief but the optimal exercise prescription to relieve pain is not clear. Following static contractions, young adults experience the greatest pain relief with low intensity, long duration contractions. The pain response to static contractions in older adults however is unknown.

PURPOSE : To compare pain reports in healthy older adults before and after static contractions of varying intensity and duration.

METHODS: Pain perception was assessed in 23 healthy older adults (11 men, 12 women; 72.0 ± 6.3 yrs) using a pressure pain device consisting of a 10 N force …


Why We Should Never Pay Down The National Debt, Neil H. Buchanan Jan 2012

Why We Should Never Pay Down The National Debt, Neil H. Buchanan

GW Law Faculty Publications & Other Works

Calls either to balance the federal budget on an annual basis, or to pay down all or part of the national debt, are based on little more than uninformed intuitions that there is something inherently bad about borrowing money. We should not only ignore calls to balance the budget or to pay down the national debt, but we should engage in a responsible plan to increase the national debt each year. Only by issuing debt to lubricate the financial system, and to support the economy’s healthy growth, can we guarantee a prosperous future for current and future citizens of the …


Learning Sparse Representations For Fruit Fly Gene Expression Pattern Image Annotation And Retreival, Lei Yuan, Alexander Woodard, Shuiwang Ji, Yuan Jiang, Zhi-Hua Zhou, Sudhir Kumar, Jieping Ye Jan 2012

Learning Sparse Representations For Fruit Fly Gene Expression Pattern Image Annotation And Retreival, Lei Yuan, Alexander Woodard, Shuiwang Ji, Yuan Jiang, Zhi-Hua Zhou, Sudhir Kumar, Jieping Ye

Computer Science Faculty Publications

Background: Fruit fly embryogenesis is one of the best understood animal development systems, and the spatiotemporal gene expression dynamics in this process are captured by digital images. Analysis of these high-throughput images will provide novel insights into the functions, interactions, and networks of animal genes governing development. To facilitate comparative analysis, web-based interfaces have been developed to conduct image retrieval based on body part keywords and images. Currently, the keyword annotation of spatiotemporal gene expression patterns is conducted manually. However, this manual practice does not scale with the continuously expanding collection of images. In addition, existing image retrieval systems based …


Reassessing The Cultural Distance Between China And The United States As Perceived By Students From The Sino-American 1+2+1 Dual Degree Program, Cynthia Letts Jan 2012

Reassessing The Cultural Distance Between China And The United States As Perceived By Students From The Sino-American 1+2+1 Dual Degree Program, Cynthia Letts

EWU Masters Thesis Collection

"As a result of the exponential growth of international commerce and academic exchange between Mainland China and the United States, this thesis examines the present-day validity of those Chinese and American cultural characteristics, such as practices and values, historically understood as defining cultural differences. Using Babiker's Cultural Distance Index (Babiker, Cox, & Miller, 1980) questionnaire (an institutionally established instrument since 1980), 45 Mainland Chinese student-sojourners conveyed their perceptions of cultural differences found in daily living. Chinese participants identified many cultural attributes that still affect the migrant's perceptions of difference. These attributes are language, food, education costs, and leisure activities. Participants …


Prevalence Of Anguillicoloides Crassus And Growth Variation In Migrant Yellow-Phase American Eels Of The Upper Potomac River Drainage, Jl Zimmerman, Sa Welsh Jan 2012

Prevalence Of Anguillicoloides Crassus And Growth Variation In Migrant Yellow-Phase American Eels Of The Upper Potomac River Drainage, Jl Zimmerman, Sa Welsh

Faculty & Staff Scholarship

No abstract provided.


Network Modeling Of Bvd Transmission, Mark Tinsley, Fraser I. Lewis, Franz Brulisauer Jan 2012

Network Modeling Of Bvd Transmission, Mark Tinsley, Fraser I. Lewis, Franz Brulisauer

Faculty & Staff Scholarship

Endemic diseases of cattle, such as bovine viral diarrhea, have significant impact on production efficiency of food of animal origin with consequences for animal welfare and climate change reduction targets. Many modeling studies focus on the local scale, examining the on-farm dynamics of this infectious disease. However, insight into prevalence and control across a network of farms ultimately requires a network level approach. Here, we implement understanding of infection dynamics, gained through these detailed on-farm modeling studies, to produce a national scale model of bovine viral diarrhea virus transmission. The complex disease epidemiology and on-farm dynamics are approximated using SIS …


The Phosphodiesterase-4 Inhibitor Rolipram Reverses Aβ-Induced Cognitive Impairment And Neuroinflammatory And Apoptotic Responses In Rats, Chuang Wang, Xue-Mei Yang, Ye-Ye Zhuo, Heng Zhou, Huan-Bing Lin, Yu-Fang Cheng, Jiang-Ping Xu, Han-Ting Zhang Jan 2012

The Phosphodiesterase-4 Inhibitor Rolipram Reverses Aβ-Induced Cognitive Impairment And Neuroinflammatory And Apoptotic Responses In Rats, Chuang Wang, Xue-Mei Yang, Ye-Ye Zhuo, Heng Zhou, Huan-Bing Lin, Yu-Fang Cheng, Jiang-Ping Xu, Han-Ting Zhang

Faculty & Staff Scholarship

No abstract provided.


Forty Years Of Increasing Suicide Mortality In Poland: Undercounting Amidst A Hanging Epidemic?, Peter Höfer, Ian R H Rockett, Peeter Värnik, Elmar Etzersdorfer, Nestor D Kapusta Jan 2012

Forty Years Of Increasing Suicide Mortality In Poland: Undercounting Amidst A Hanging Epidemic?, Peter Höfer, Ian R H Rockett, Peeter Värnik, Elmar Etzersdorfer, Nestor D Kapusta

Faculty & Staff Scholarship

No abstract provided.


Mechanism Of Action Of A Novel Antifungal Compound, Amber Ward Jan 2012

Mechanism Of Action Of A Novel Antifungal Compound, Amber Ward

Honors Theses

Opportunistic fungal infections have become problematic in recent years. There has been an emergence of new fungal pathogens, development of antifungal resistance, and increasing prevalence. In addition, toxicity, resistance, and lack of efficacy as a single agent limit the effectiveness of current antifungal drugs. Therefore, new drugs targeting new pathways are greatly needed. An analog derived from the marine natural product phloeodictine, analog PHL5-34A, was identified as having strong in vitro antifungal activity. In this study, its mechanism of action (MOA) was investigated in the model yeast, Saccharomyces cerevisiae. This study made use of a collection of 166 yeast mutants …


Working Towards A Solution To The Obesity Epidemic: A Marketer's Perspective, Elizabeth Ann Clippard Jan 2012

Working Towards A Solution To The Obesity Epidemic: A Marketer's Perspective, Elizabeth Ann Clippard

Honors Theses

The obesity epidemic is a social issue in that critics are quick to blame business and government for failing the consumers. The truth is that all three parties have failed each other by allowing such a cultural change to occur. The issue is similar to the tobacco public health crisis following the spike in lung cancer in the 1950s and 60s. The tobacco companies were blamed entirely for their unhealthy products and the government still spends millions today regulating their products. In order to improve upon this course of action, I believe that a more cooperative solution exists in order …


Angiotensin Ii As A Potential Regulator Of Inflammatory Cytokines In Inducing Hypertension In Systemic Lupus Erythematosus, Khush Singh Aujla Jan 2012

Angiotensin Ii As A Potential Regulator Of Inflammatory Cytokines In Inducing Hypertension In Systemic Lupus Erythematosus, Khush Singh Aujla

Honors Theses

The disease Systemic Lupus Erythematosus is a chronic inflammatory, autoimmune disorder that primarily affects women during their reproductive years. Women with SLE are at a greater risk of developing hypertension, which increases their risk of mortality from a cardiac related event. A proposed mechanism for SLE hypertension suggests that inflammation in the kidneys causes renal dysfunction, presumably resulting in less water excretion, increased plasma volume, and thus high blood pressure. This experiment tests the hypothesis that the T-cells from a mouse model of SLE hyper secrete the inflammatory cytokines IL-17, IL-10, and DFN- y, and are more sensitive to the …


An Investigation Of Host Variation In The Host-Parasite Interaction Of Sciurus Carolinensis And Cuterebra Emasculator, Miles Moore Debardeleben Jan 2012

An Investigation Of Host Variation In The Host-Parasite Interaction Of Sciurus Carolinensis And Cuterebra Emasculator, Miles Moore Debardeleben

Honors Theses

Within a population, susceptibility to parasitism may vary. Individuals possessing certain intrinsic or extrinsic traits are often more likely to be parasitized than individuals within that population that do not possess those certain traits. As a result, parasites can have profound effects of the population dynamics of theirs hosts. Much research has been done on the host-parasite interaction of the eastern grey squirrel {Sciurus caroUnensis) and the tree squirrel hot fly {Cuterebra emasculator). However, relatively little research has been done on host susceptibility to this parasite. Knowing that bot flies can lower reproductive success, reduce fitness, and cause death of …


Investigation Of Brown Recluse (Loxosceles Reclusa) And Black Widow (Latrodectus Mactans) Spider-Bite Diagnoses By Medical Professionals Across Three Regions Of Mississippi, Hillary Michelle Howell Jan 2012

Investigation Of Brown Recluse (Loxosceles Reclusa) And Black Widow (Latrodectus Mactans) Spider-Bite Diagnoses By Medical Professionals Across Three Regions Of Mississippi, Hillary Michelle Howell

Honors Theses

During 4 weeks of the spring of 2011 and 5 weeks of the fall of 2011, interviews were conducted with medical professionals practicing in Mississippi regarding the diagnosis of brown recluse {Loxosceles reclusa) and black widow {Latrodectus mactans) spider bites. During the spring, a total of 19 interviews were held with emergency room physicians and dermatologists practicing in urban and rural, non-medically underserved areas of Mississippi. The participants varied in their location of practice across the 3 regions of Mississippi. During the fall, a total of 5 interviews were conducted with nurse practitioners and one pediatrician practicing in rural, medically …


Strict Liability In Negligence, Kenneth S. Abraham Jan 2012

Strict Liability In Negligence, Kenneth S. Abraham

DePaul Law Review

No abstract provided.


Reflections On Tort And The Administrative State, Robert L. Rabin Jan 2012

Reflections On Tort And The Administrative State, Robert L. Rabin

DePaul Law Review

No abstract provided.


An Alternative Explanation For No-Fault's Demise, Nora Freeman Engstrom Jan 2012

An Alternative Explanation For No-Fault's Demise, Nora Freeman Engstrom

DePaul Law Review

No abstract provided.


Professor Rabin And The Administrative State , Peter H. Schuck Jan 2012

Professor Rabin And The Administrative State , Peter H. Schuck

DePaul Law Review

No abstract provided.


Pure Confusion: Should Pure Licensors Share The Products Liability Of Manufacturers And Sellers Of Dangerously Defective Products?, Stephen C. Jarvis Jan 2012

Pure Confusion: Should Pure Licensors Share The Products Liability Of Manufacturers And Sellers Of Dangerously Defective Products?, Stephen C. Jarvis

DePaul Law Review

No abstract provided.


The Federal Employers' Liability Act: Sense And Nonsense About Causation, Michael D. Green Jan 2012

The Federal Employers' Liability Act: Sense And Nonsense About Causation, Michael D. Green

DePaul Law Review

No abstract provided.