Digital Commons Network^™

Cdk1 And Plk1 Mediate A Clasp2 Phospho-Switch That Stabilizes Kinetochore–Microtubule Attachments, Ana R. R. Maia, Zaira Garcia, Lilian Kabeche, Marin Barisic

Dartmouth Scholarship

Accurate chromosome segregation during mitosis relies on a dynamic kinetochore (KT)-microtubule (MT) interface that switches from a labile to a stable condition in response to correct MT attachments. This transition is essential to satisfy the spindle-assembly checkpoint (SAC) and couple MT-generated force with chromosome movements, but the underlying regulatory mechanism remains unclear. In this study, we show that during mitosis the MT- and KT-associated protein CLASP2 is progressively and distinctively phosphorylated by Cdk1 and Plk1 kinases, concomitant with the establishment of KT-MT attachments. CLASP2 S1234 was phosphorylated by Cdk1, which primed CLASP2 for association with Plk1. Plk1 recruitment to KTs …

The Restyled Federal Rules Of Evidence, Roger C. Park

Faculty Scholarship

No abstract provided.

The Paranoid Style In Regulatory Reform, Jodi L. Short

Faculty Scholarship

No abstract provided.

Users' Perceptions Regarding Networking And Resource Sharing In Selected Academic Libraries Of Bangladesh, Abul Kalam Siddike

Library Philosophy and Practice (e-journal)

Across the disciplines, technology is spawning brand new carries in even as it changes in the way we performed old ones. Standing at the edge of 21^st century probably there is no dispute over the recognition of technologies in information activities. Unprecedented changes in the use of information are reshaping our personal activities, our community and organizational practices. Information and Communication Technologies (ICT) bring the global information to our finger end. With the emergence of Internet, information kept in different locations has become asset of the world community bringing –almost every day in equal platform. To control over the …

Use Of E-Resources By Life Scientists: A Case Study Of Sambalpur University, India, Bipin Bihari Sethi, K. C. Panda

Library Philosophy and Practice (e-journal)

E-resources in collaboration with Internet have become a sign of modern age being an invaluable tool for teaching, learning, and research. The library and information landscape has transformed with the onset of the digital era and today traditional libraries have changed their roles to serve as ‘Knowledge Centers’ with priority on value added electronic information services. Academic and research institutions are focusing on how best they can facilitate research by canalizing specific information services which compliment as cutting-edge technology. With the advent of globalization in the realm of education, there has been an information explosion. Most of the science and …

User Education Programs In Academic Libraries: The Experience Of The International Islamic University Malaysia Students, Shammasi Ali Suleiman

Library Philosophy and Practice (e-journal)

The library supports the reading and research needs for that particular institution. It is the library's responsibility to provide better services to its clients to make sure that information sources, services and resources are well utilized for user benefits; hence user education program is very crucial for user's achievement. The aim of this paper is to identify perception of user education program at International Islamic University (IIUM) library, to identify Module of user education program at IIUM library and to develop searching skills for users. The descriptive survey is adopted for the study. The population is Undergraduate and Postgraduate students …

Enterprise Risk Management: Understanding And Communicating Risk Appetite, Larry Rittenberg, Frank Martens, Committee Of Sponsoring Organizations Of The Treadway Commission

Association Sections, Divisions, Boards, Teams

No abstract provided.

The Impact Of Kenya National Library Services (Knls), Kisumu Provincial Mobile Library Services On Education In Kisumu County,Kenya., James Macharia Tutu

Library Philosophy and Practice (e-journal)

The purpose of this study was to establish the impact of KNLS Kisumu provincial mobile library services on education in Kisumu County. Qualitative research approach was used to conduct the study. Interviews were used to collect data and data was analysed qualitatively. Ten schools were sampled for the study, six secondary schools and four primary schools. Personnel working with KNLS Kisumu provincial mobile library services and teachers in sampled schools were interviewed. The study established that the impact of KNLS Kisumu provincial mobile library services on education in Kisumu County was positive. The study recommends the diversification of the mobile …

Election Law Behind A Veil Of Ignorance, Chad W. Flanders

All Faculty Scholarship

Election law struggles with the question of neutrality, not only with its possibility — can election rules truly be neutral between parties?—but also with its definition. What does it mean for election laws to be ― neutral? This Article examines one form of election law neutrality, found in what it terms ― veil of ignorance rules Such rules are formed in circumstances where neither party knows which rule will benefit its candidates in future elections.

This Article considers the existence of veil of ignorance rules in two recent election law controversies: the rule that write-in ballots must be spelled correctly …

Cost As A Sentencing Factor: Missouri's Experiment, Chad W. Flanders

All Faculty Scholarship

In sentencing offenders, should judges take into account the different costs of possible punishments? In 2010, Missouri gave sentencing judges, in addition to information about the nature and severity of the offense and the criminal history of the offender, the price tag of various punishments: prison cost about $17,000 a year, compared to probation, which is much cheaper (about $7000 per year). Judges were allowed, even encouraged, to base their sentences on how much it each sentence would cost the state. The move was a subject of considerable national and local controversy.

This essay represents the first sustained look at …

The Bizarre Law & Economics Of 'Business Roundtable V. Sec', Grant M. Hayden, Matthew T. Bodie

All Faculty Scholarship

Corporations are legal entities designed to foster certain kinds of collective economic activity. The decisionmaking power within a corporation ultimately rests with a board of directors elected by shareholders. Shareholders, however, do not use anything like a conventional ballot in these elections; instead, they fill out a “proxy ballot,” delivered to them by the incumbent board. This proxy ballot lists only the incumbent board’s chosen nominees, very often the board members themselves. If a shareholder wants to run for director or propose another nominee for the board, she needs to provide all other shareholders with a separate proxy ballot — …

Reverse Abstention, Samuel P. Jordan

All Faculty Scholarship

State courts decide claims based on federal or sister-state law every day. Although the applicable constitutional provisions are different, there are significant similarities in the way the Supreme Court conceptualizes the constraints on how those claims must be treated. One project of this Article is to chart those similarities, providing a unified account of the Court’s approach to judicial federalism. The larger project, however, is not to describe the Court’s approach, but to replace it. The current emphasis on discrimination and interference imposes burdensome and unwarranted obligations on state courts. A more flexible approach to judicial federalism is needed, and …

Does America Need Public Housing?, Peter W. Salsich

All Faculty Scholarship

Does Twenty-First Century America Need Publicly-Owned Housing? This question was being asked in 2011, as an era of sharply-curtailed discretionary government spending dawned in the aftermath of the debt limitation crisis. From its inception in 1937 to the present, public housing remains the housing program with the deepest subsidy, designed for households who cannot compete effectively in the private housing market and, since the 1950s, the program that reaches the lowest income quadrant of society. Questions posed in 2011 center around the future of the 1.1 million public housing units in existence (down from 1.4 million two decades ago), all …

New Nip In The Bud: Does The Obama Board's Preemptive Strike Doctrine Enhance Tactical Employment Law Strategies?, Michael C. Duff

All Faculty Scholarship

In this essay I revisit the classic debate concerning when worker activity is sufficiently “concerted” to be covered by the National Labor Relations Act, a statute covering certain private sector protected “concerted” activity by workers. When workers are obviously engaged in concerted “labor” activity — classically activity like striking, picketing, or even just complaining about working conditions — they are generally protected against employer reprisal for doing so. Over the last few decades there has been disagreement about the definition and limits of “concert.” My renewed interest in this dormant but not dead subject was piqued by the “Obama Board’s” …

Conversion From Enzyme-Inducing Antiepileptic Drugs To Topiramate: Effects On Lipids And C-Reactive Protein., Scott Mintzer, Christopher T Skidmore, Sara J Rankin, Inna Chervoneva, Edward Pequinot, David M Capuzzi, Michael R Sperling

Department of Neurology Faculty Papers

PURPOSE: We previously demonstrated that converting patients from the enzyme-inducers phenytoin or carbamazepine to the non-inducers levetiracetam or lamotrigine reduces serum lipids and C-reactive protein (CRP). We sought to determine if the same changes would occur when patients were switched to topiramate, which has shown some evidence of enzyme induction at high doses. We also examined the effects of drug switch on low-density lipoprotein (LDL) particle concentration.

METHODS: We converted 13 patients from phenytoin or carbamazepine monotherapy to topiramate monotherapy (most at doses of 100-150 mg/day). Fasting lipids, including LDL particle concentration, and CRP were obtained before and ≥6 weeks …

The Hierarchy That Wasn’T There: Elevating “Usage” To Its Rightful Position For Contracts Governed By The Cisg, William P. Johnson

All Faculty Scholarship

Under domestic U.S. sales law, usage of trade is relevant in ascertaining the meaning of an agreement, and it can be used to supplement, qualify, or explain an agreement. However, usage of trade may not be used under domestic U.S. sales law to contradict a written agreement. Moreover, any course of performance or course of dealing between the parties will prevail over inconsistent usage of trade. The United Nations Convention on Contracts for the International Sale of Goods, or CISG, similarly provides for consideration of usage to establish the terms of the agreement between the parties, as well as to …

Follow The Leader: The Advisability And Propriety Of Considering Cost And Recidivism Data At Sentencing, Lynn S. Branham

All Faculty Scholarship

The Missouri Sentencing Advisory Commission has begun to provide judges with information that enables them, before imposing a sentence, to compare the financial costs of several different sentencing options and the recidivism risks they pose. Although this initiative has sparked controversy, I, for one, favor taking steps like this one to help extricate us from the “same ole, same ole” sentencing box in which uninformed, and sometimes misinformed, sentencing decision making is the norm.

This article provides an overview of six of the primary reasons why providing judges some very basic facts about the financial cost of several sentencing options …

Evaluating The Recidivism Rates For Parolees Enrolled In M-Coit, A Community Mental Health/ Substance Abuse Treatment Program, Pamela J. Walsh, David Atkinson

Michigan Journal of Public Health

This paper focuses on an evaluation of recidivism rates of parolees with severe and persistent mental illness enrolled in a mental health/ substance abuse treatment program (M-COIT) at a community mental health center in southeastern Michigan. The two partners in the study were a community mental health center located in a city bordering the southern part of Detroit and Eastern Michigan University located in Ypsilanti, Michigan. The purpose of the study was to identify the recidivism rates and factors that affected these rates for parolees who participated in the M-COIT Program. This was a retrospective medical record review. The practical …

Using Community-Based Participatory Research To Investigate The Effectiveness Of Hiv/Aids Risk Reduction Counseling In An Urban African-American Community, Alicia Streater, Julie Gleason-Comstock, Cindy B. Calhoun, Barbara Jones, Silas Norman Jr.

Michigan Journal of Public Health

Introduction: Risk reduction counseling is an important component in HIV/AIDS prevention. Community-based participatory research (CBPR) was conducted to determine if a single counseling session was as effective as a two-session intervention in reducing risk behavior. Methods: Community and academic investigators jointly developed the study design. A convenience sample of 242 persons was randomized to receive either a two session intervention with Conventional HIV Testing (CHT) or a one session intervention with HIV Rapid Testing (HRT). Participants completed a risk assessment immediately preceding the test and a risk reduction plan after the test; CHT participants received a second risk reduction session. …

Mark As Story: Retrospect And Prospect [Review] / Iverson, Kelly R. And Christopher W. Skinner, Eds., Thomas Shepherd

Andrews University Seminary Studies (AUSS)

No abstract provided.

Christian Philosophy As A Way Of Life, Bruce Ellis Benson

Andrews University Seminary Studies (AUSS)

No abstract provided.

Lessons From Alexandria: The Trinity, The Soteriological Problem, And The Rise Of Modern Adventist Antitrinitarianism, Darius Jankiewicz

Andrews University Seminary Studies (AUSS)

No abstract provided.

William Miller And The Rise Of Adventism [Review] / Knight, George R., Gary Land

Andrews University Seminary Studies (AUSS)

No abstract provided.

The Letter To The Hebrews [Review] / O'Brien, Peter T., Erhard H. Gallos

Andrews University Seminary Studies (AUSS)

No abstract provided.

Andrews University Seminary Studies Turns 50!, John W. Reeve

Andrews University Seminary Studies (AUSS)

No abstract provided.

The Liminal Church: Exilic Consciousness And Adventist Theopolitics, Ante Jerončić

Andrews University Seminary Studies (AUSS)

No abstract provided.

Minor Prophets Ii [Review] / John Goldingay And Pamela Scalise, Merling K. Alomia

Andrews University Seminary Studies (AUSS)

No abstract provided.

God And Stephen Hawking: Whose Design Is It Anyway? [Review] / John C. Lennox, Gary W. Burdick

Andrews University Seminary Studies (AUSS)

No abstract provided.