Digital Commons Network^™

ΑVΒ3 Integrin Crystal Structures And Their Functional Implications, Xianchi Dong, Li Zhi Mi, Jianghai Zhu, Wei Wang, Ping Hu, Bing Hao Luo, Timothy A. Springer

Faculty Publications

Many questions about the significance of structural features of integrin αVβ3 with respect to its mechanism of activation remain. We have determined and re-refined crystal structures of the αVβ3 ectodomain linked to C-terminal coiled coils (αVβ3-AB) and four transmembrane (TM) residues in each subunit (αVβ3-1TM), respectively. The αV and β3 subunits with four and eight extracellular domains, respectively, are bent at knees between the integrin headpiece and lower legs, and the headpiece has the closed, low-affinity conformation. The structures differ in the occupancy of three metal-binding sites in the βI domain. Occupancy appears to be related to the pH of …

Murray V. State Respondent's Brief Dckt. 39400

Idaho Supreme Court Records & Briefs, All

No abstract provided.

The Advocate, November 6, 2012, Minnesota State University Moorhead

The Advocate

No abstract provided.

The Sun Star ( November 6th, 2012), N/A N/A

Sun Star

No abstract provided.

Model Based Diagnostics And Prognostics Of Three-Phase Induction Motor For Vapor Compressor Applications, Raja Sekhar Kraleti, Maciej Jan Zawodniok, Sarangapani Jagannathan

Electrical and Computer Engineering Faculty Research & Creative Works

In this work, a novel scheme for detection and prediction of multiple simultaneous faults in a three-phase induction motor in the context of vapor compression applications is presented. Induction motors used in vapor compression systems operate under variable speed conditions with variable frequencies. Such dynamic operating conditions may cause an occurrence of multiple, simultaneous faults including insulation degradation and a rotor bar breakage. These faults, when left undetected, lead to the failure of the motor and the entire vapor compression system. Hence, a condition monitoring of induction motors is essential. Conventional fault detection methods have various drawbacks including high implementation …

In Re: Kevin Flood

2012 Decisions

USDC for the Western District of Pennsylvania

Daniel Delker V.;Blaker

2012 Decisions

USDC for the Western District of Pennsylvania

Abdus Shahid V.;Borough Of Eddystone

2012 Decisions

USDC for the Eastern District of Pennsylvania

Lall Ramnauth V.;Attorney General United States

2012 Decisions

Agency

Xiu Li V. Atty;Gen Usa

2012 Decisions

Agency

The George-Anne, Georgia Southern University

The George-Anne

• Russell Suspended After Arrest at Bars
• News
• Opinions
• Arts & Entertainment
• Classifieds
• Puzzles/ Comics
• Sports

Stony Brook Press, V. 34, N. 05, Stony Brook University. Stony Brook Press.

Stony Brook Press

v. 34, n. 05, v.:ill. ; 38 cm (original analog pub.)

Audit Mechanisms For Provable Risk Management And Accountable Data Governance, Jeremiah Blocki, Nicolas Christin, Anupam Datta, Arunesh Sinha

Research Collection School Of Computing and Information Systems

Organizations that collect and use large volumes of personal information are expected under the principle of accountable data governance to take measures to protect data subjects from risks that arise from inapproriate uses of this information. In this paper, we focus on a specific class of mechanisms—audits to identify policy violators coupled with punishments—that organizations such as hospitals, financial institutions, and Web services companies may adopt to protect data subjects from privacy and security risks stemming from inappropriate information use by insiders. We model the interaction between the organization (defender) and an insider (adversary) during the audit process as a …

November 6, 2012, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

Extreme Levels Of Noise Constitute A Key Neuromuscular Deficit In The Elderly, Niklas König Ignasiak

Physical Therapy Faculty Articles and Research

Fluctuations during isometric force production tasks occur due to the inability of musculature to generate purely constant submaximal forces and are considered to be an estimation of neuromuscular noise. The human sensori-motor system regulates complex interactions between multiple afferent and efferent systems, which results in variability during functional task performance. Since muscles are the only active component of the motor system, it therefore seems reasonable that neuromuscular noise plays a key role in governing variability during both standing and walking. Seventy elderly women (including 34 fallers) performed multiple repetitions of isometric force production, quiet standing and walking tasks. No relationship …

Did Dewey Presage The 1989 National Council Of Teachers Of Mathematics Standards?, Teresa M. Finken

Education and Culture

The general theme of change in philosophy over time is due to traditional customs and beliefs failing to regulate society. This theme drove both John Dewey's Progressive Movement and the creation of the Curriculum and Evaluation Standards for School Mathematics (1989) by the National Council of Teachers of Mathematics (NCTM). The remarkable similarity in thought between Dewey's writings and the Standards is the basis for this paper. The point of view is from the Standards looking back to find Dewey's similar ideas. Although Dewey's views of mathematics per se are not extensively explicated, his overarching views on learning content resonate …

Everything Within Reach, Judith Chalmer

Education and Culture

No abstract provided.

Authority, Social Change, And Education: A Response To Dewey's Critics, James Scott Johnston

Education and Culture

In this paper, I want to examine and challenge certain criticisms of Dewey's conception of authority. These criticisms are, broadly speaking, of two species. The first set of criticisms involves what critics have labeled Dewey's "strong" authority. These critics, the so-called "Illinois Revisionists," argue that embedded in Dewey's social and educational philosophy are assumptions about authority that lead the critics to speculate that the legitimation of authority is predicated upon an expert, professional class. This class maintains power and social control through the use of scientific, technical, and rational means. In terms of education, these critics conclude that schooling is …

An Alternative Framework For Ethics Instruction In Social Education, Thomas J. Misco Jr., Gregory E. Hamot

Education and Culture

Ethics are central to social education, and making ethical decisions underlies the purpose of teaching critical thinking and interpretive skills in the classroom. The point in acquiring these skills is to apply them in the real world when deciding "what ought to be," "right from wrong," and "good from bad." Few educational philosophers would disagree up to this point. However, when discussion begins on how to teach ethics, beliefs diverge considerably.

Ironically, both the extreme left and extreme right wings of educational thought seek the same end, that of ethics inculcation. Inculcation of anything is a dangerous if not unethical …

Curriculum Wars And Cold War Politics: The Struggle For Academic Freedom In Higher Education, Karen Lea Riley, Barbara Slater Stern

Education and Culture

During the early 1960s, in the formative years of Florida's newest university, the University of South Florida located in Tampa, the Florida Investigative Committee in true McCarthy-era style, set up its "Star Chamber" interviews with students and "others" at local motels near the University. The purpose of these "interviews" was to ferret out information about university administrators and instructors which would point to either their innocence or their guilt in terms of communist party membership, homosexuality, or the teaching of atheism. After an exhaustive process which left the intellectual community on Florida's West Coast shaken and dismayed at what it …

Making Classrooms Culturally Sensitive, Robert C. Morris, Nancy G. Mims

Education and Culture

It is felt by many that as American schools and educators become more and more sensitive to the diversity of their community, their students can be guided to appreciate and respect these differences and to coexist peacefully. Various combinations of cultures such as African-Americans, Irish and German-Americans, Hispanics, Chinese-Americans to name a few, are learning how to work and live together while maintaining their own cultural heritage. The students of today who embrace their cultural heritage are trying to keep the values of their parents and grandparents, and still fit in with the students and cultures surrounding them. This dual …

The Missouri-Iowa (Mi) Plan For Course Improvement: Traveling Toward Tqm: The Otis Route, Judy Griffith, John Mclure, Jann Weitzel

Education and Culture

Three years ago, our odyssey to apply Deming's Total Quality Management (TQM) to college courses began. As we considered alternative routes to effective teaching, we found it necessary to consider carefully the organization of our classrooms, technology used for instruction and assessment, and student input opportunities as we strove to shape our courses. This is, for the purposes of this paper, the OTIS (organization, technology, input, shaping) route. Though we consider ourselves to be far from the end of the journey, the experiences have been challenging and renewing, and we would like to share some of our work with you. …

"I Used To Be Very Smart:" Children Talk About Immigration, Carol Korn

Education and Culture

In the paper which follows, children's narrative as a genre which offers a closer look at childhood experience is explored. The children's own stories of their immigration experiences are examined for the meanings which these transitions hold for them, and for the implications for educational practice they suggest. Landscapes of home and stories about school figure prominently in the children's narratives, and are juxtaposed against current life experiences. This paper will explore the role of the imagination in enabling children to make connections between their lives before and after immigration and suggest implications for educational practice.

Towards A Flexible Curriculum: John Dewey's Theory Of Experience And Learning, Joop W. A. Berding

Education and Culture

Positively stated, a reconceptualization of curriculum will most certainly have to take its cue from the American philosopher and pedagogue John Dewey (1859-1952). His work in philosophy and education is one great attempt to overcome dysfunctional dualisms like between the child and the curriculum, freedom and discipline, the individual and the society, body and mind. I will use my reconstruction of his theory of experience and learning to challenge the claim made by the Tanners (Tanner and Tanner, 1980, 1988; D. Tanner, 1982; L.N. Tanner, 1982) that Dewey must be regarded as the ancestor of 'modern' curriculum theory as formulated …

Democratic Schooling: Toward A Renewed End-In-View, Matthew D. Davis

Education and Culture

American political leaders and editorial pundits routinely decry the demise of democratic life in the nation. Voting, at all levels, remains at abysmally low levels. Public rhetoric routinely is shrill, often unseemly; it lacks civility. Political discourse in such an environment is clearly impoverished. Combatants for public attention and approval war over visions of the public good. They stand entrenched and immobile, refusing to yield or shift positions. Their ground of disputation frequently is neither level nor common. These tortured circumstances of civic reality are viewed much too often and like so many past and present social problems, as the …

Does "The Knowing" Alter "The Known"? On The Troublesome Relation Of Facts And Ideas In A Deweyan Epistemology, Chris Mccarthy

Education and Culture

The claim I've made is that there is an often overlooked ontological realism that is properly associated with the Deweyan pragmatic inquiry, the implication of which is that "what" might be discovered in inquiry, what might be known, is in an important sense set in advance, and is independent of the beliefs, hopes and preferences of the inquirer(s). The "production of knowledge," in virtue of this external limiting determination, is indeed the production of that which is stable, secure, general, and, in one very important sense, "transcendent" of the concrete particulars of its originating conditions.

This is a rather controversial …

Alice Miel And Democratic Schooling: An Early Curriculum Leader's Ideas On Social Learning And Social Studies, Elizabeth Anne Yeager

Education and Culture

Alice Miel, a nationally prominent curriculum development scholar-practitioner at Teachers College of Columbia University for some three decades (1942-1971), frequently has been overlooked in research on the nature and evolution of the curriculum field and the progressive education movement. Furthermore, her contributions have been overlooked even as attention to women in the curriculum field and in educational history has risen. This study addresses this oversight.

Miel became a leading figure in the curriculum field largely on the basis of her progressive-era advocacy and practice of democratic social learning as a primary goal of schooling in the United States. This study …

The Daily Egyptian, November 05, 2012, Daily Egyptian Staff

November 2012

No abstract provided.

In A Model Of Batten Disease, Palmitoyl Protein Thioesterase-1 Deficiency Is Associated With Brown Adipose Tissue And Thermoregulation Abnormalities, Alfia Khaibullina, Nicholas Kenyon, Virginia Guptill, Martha M. Quezado, Li Wang, Deloris Koziol, Robert Wesley, Pablo R. Moya, Zhongjian Zhang, Arjun Saha, Anil B. Mukherjee, Zenaide M.N. Quezado

Anesthesiology and Critical Care Medicine Faculty Publications

Infantile neuronal ceroid lipofuscinosis (INCL) is a fatal neurodegenerative disorder caused by a deficiency of palmitoyl-protein thioesterase-1 (PPT1). We have previously shown that children with INCL have increased risk of hypothermia during anesthesia and that PPT1-deficiency in mice is associated with disruption of adaptive energy metabolism, downregulation of peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α), and mitochondrial dysfunction. Here we hypothesized that Ppt1-knockout mice, a well-studied model of INCL that shows many of the neurologic manifestations of the disease, would recapitulate the thermoregulation impairment observed in children with INCL. We also hypothesized that when exposed to cold, Ppt1-knockout …

Commonwealth Times 2012-11-05

Commonwealth Times, 1969-

No abstract provided.