Digital Commons Network^™

Inquiry-Based Science Education As Multiple Outcome Interdisciplinary Research And Learning (Moirl), Allan Feldman, Angela M. Chapman, Vanessa Vernaza-Hernández, Dilek Ozalp, Fayez Alshehri

Teaching and Learning Faculty Publications

The article provides the basis for a model of inquiry-based science education in which K-12 teachers’ and pupils’ engage in authentic science experiences as participants of a scientific research project, which we refer to as Multiple Outcome Interdisciplinary Research and Learning (MOIRL). We provide the basis for the model for inquiry based science education (IBSE) by first describing how the model came about through our 10 years of research on how people learn to do science in research groups. We then turn to the literature on the relationship among scientific inquiry, inquiry learning and MOIRL. As our case studies of …

Effect Of Iron Chelators On Methemoglobin And Thrombin Preconditioning., Jing Chen-Roetling, Jesse Sinanan, Raymond F. Regan

Department of Emergency Medicine Faculty Papers

Cell loss immediately adjacent to an intracerebral hemorrhage may be mediated in part by the toxicities of extracellular hemoglobin (Hb) and thrombin. However, at low concentrations, these proteins induce tolerance to hemin and iron that may limit further peri-hematomal injury as erythrocyte lysis progresses. The mechanisms mediating these preconditioning effects have not been completely defined, but increased expression of both heme oxygenase (HO)-1 and iron binding proteins likely contributes. In the present study, we hypothesized that iron chelator therapy would attenuate this protective response. Pretreatment of cortical glial cultures (> 90 % GFAP+) with 3 μM methemoglobin (metHb) or 5 …

Evaluation Of The Recombination Efficiencies Of Flp Proteins, Linh Duy Nguyen

Graduate Theses and Dissertations

Site-specific recombination systems are powerful tools for genetic modification. They have been used to integrate a transgene into a pre-defined locus and to remove marker genes from a transgene locus. Two of the most widely used site-specific recombination systems in plants are the Cre/lox system from the bacteriophage P1 and the FLP/FRT system from the yeast Saccharomyces cerevisiae. The Cre/lox system is well-characterized and is the first choice in application of site-specific recombination system. However, some applications such as marker-free site-specific gene integration require the use of two recombination systems. In addition, the availability of alternative recombination systems can offer …

Limited Sampling Estimates Of Epigallocatechin Gallate Exposures In Cirrhotic And Noncirrhotic Patients With Hepatitis C After Single Oral Doses Of Green Tea Extract., Dina Halegoua-De Marzio, Walter K. Kraft, Constantine Daskalakis, Xie Ying, Roy L Hawke, Victor J. Navarro

Division of Gastroenterology and Hepatology Faculty Papers

BACKGROUND: Epigallocatechin-3-gallate (EGCG) has antiangiogenic, antioxidant, and antifibrotic properties that may have therapeutic potential for the treatment of cirrhosis induced by hepatitis C virus (HCV). However, cirrhosis might affect EGCG disposition and augment its reported dose-dependent hepatotoxic potential.

OBJECTIVE: The safety, tolerability, and disposition of a single oral dose of EGCG in cirrhotic patients with HCV were examined in an exploratory fashion.

METHODS: Eleven patients with hepatitis C and detectable viremia were enrolled. Four had Child-Pugh (CP) class A cirrhosis, 4 had Child-Pugh class B cirrhosis, and 3 were noncirrhotic. After a single oral dose of green tea extract 400 …

Megathrust Splay Fault Geometry In Prince William Sound, Alaska, Shaun Patrick Finn

Boise State University Theses and Dissertations

I present marine seismic reflection results from Prince William Sound, Alaska that document the location of active faults related to the subduction zone processes.

Subduction zones along convergent margins experience large earthquakes, magnitude >8, with recurrence intervals on the order of centuries. Smaller magnitude earthquakes with shorter recurrence intervals are probable along the same subduction zone fault zones. Convergent margin earthquakes also are associated with high uplift rates and tsunami generation, yet the location and uplift history of most tsunamigenic faults are unknown. In this thesis, I present the processed results of high resolution marine seismic reflection data of Prince …

Annual Report Of Research And Creative Productions By Faculty And Staff, January To December, 2012, Research And Creative Productions Committee. Morehead State University.

Office of Research and Sponsored Programs Reports and Publications

Annual Report Of Research and Creative Productions by Faculty and Staff from January to December, 2012.

Clarity At Sentencing Deferred: How Dorsey V. United States Could Have Reformed Federal Sentencing, Jonathan Ross

Duke Journal of Constitutional Law & Public Policy

No abstract provided.

December 2012 News Releases, University Of Montana--Missoula. Office Of University Relations

University of Montana News Releases, 1928, 1956-present

No abstract provided.

Biodiesel Production From Mixed Culture Algae Via A Wet Lipid Extraction Procedure, Ashik Sathish

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Development of renewable sources of energy has received significant interest due to the rising costs of energy and the environmental impact of using fossil fuels. Biodiesel production from renewable sources of oil has shown promise of helping to replace or reduce dependence on petroleum based diesel thereby reducing demand for crude oil. Microalgae have been considered as a strong candidate for the production of large quantities of renewable oil for biodiesel production.

Microalgae are single cell photosynthetic organisms that posses the capability to produce renewable oil at rates much faster than land based plants and crops. In addition, microalgae can …

Synthesis And Biological Activity Of Aminoglycosides And 1,4-Naphthoquinone Derivatives, Marina Fosso Yatchang

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The research described in this dissertation is at the interface of organic chemistry and biology, and it aimed at designing and synthesizing biologically active molecules for the possible development of therapeutic agents.

Spinal muscular atrophy is an incurable disease that affects 1 in every 6000 babies, making it the leading genetic cause of infant mortality. While no treatment is available, efforts are being taken to solve this issue. Part of the work outlined in this dissertation was carried out in collaboration with researchers from the University of Missouri to investigate a potential therapeutic for this disease.

In addition, the continuous …

The Effects Of Bison On Cattle Winter Range In The Henry Mountains Of South Central Utah: Resolving A Conflict, Ian M. Ware

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The American Bison in the Henry Mountains are one of the last free-roaming, genetically pure herds of bison remaining in North America. Over the last decade, the herd has used a cattle winter range during the summer and early fall, creating a conflict between the wildlife officials who manage the bison population, and Bureau of Land Management officials and local ranchers who manage the rangeland. At the heart of this conflict is the question of whether bison are negatively impacting the rangeland resource, potentially reducing the abundance of preferable plant species. Negative impacts could include reduced forage availability in the …

Population Dynamics And Movements Of Translocated And Resident Greater Sage-Grouse On Anthro Mountain, Utah, Natasha W. Gruber

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Greater sage-grouse (Centrocercus urophasianus) populations have declined range-wide. Species translocations have been identified as a conservation strategy to augment declining populations in restored habitats. I evaluated protocols previously used to successfully translocate greater sage-grouse in Utah by comparing annual production, survival, habitat use, integration and seasonal movements of translocated birds and their chicks to the resident population. To conduct this study, I translocated 60 greater sagegrouse hens captured and radio-collared on Parker Mountain to Anthro Mountain in the spring of 2009 and 2010. I also captured and radio-collared 19 resident hens to serve as my control group. All …

Factors Influencing Relocation Success Of Utah Prairie Dog (Cynomys Parvidens), Rachel Curtis

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Utah prairie dogs have been extirpated in 90% of their historic range due to introduced disease, eradication, and habitat destruction. Most of the population lives on private land where animals burrow in lawns and agricultural fields, which keeps this threatened species continually in conflict with landowners. The Utah Division of Wildlife Resources has been relocating prairie dogs from private to public land since the 1970s, but relocations have been largely unsuccessful due to high mortality. Prairie dogs are highly social animals, but they are usually relocated without regard to their family group, or coterie. Coteries typically consist of one reproductive …

Taiwanese Willingness To Communicate In English: Can Watching American Television Programs Help?, Yu-Ting Chien

UNLV Theses, Dissertations, Professional Papers, and Capstones

This study explored the relationship between Taiwanese audiences' use of American television programs and their willingness to communicate in English. Taiwanese participants filled out an online survey consisted of questions from uses and gratifications constructs and willingness to communicate constructs. In addition, different subtitle settings were also examined.

Results indicated that participants with high integrative motivation consuming information from American television programs, in addition, the setting of subtitles were associated with perceived communication competence, integrative motivation, language anxiety and social interaction motivation.

Restoration Of Biological Soil Crust On Disturbed Gypsiferous Soils In Lake Mead National Recreation Area, Eastern Mojave Desert, Lindsay P. Chiquoine

UNLV Theses, Dissertations, Professional Papers, and Capstones

Biological soil crusts (BSCs) are sensitive to anthropogenic disturbances. Natural recovery takes many years. Active restoration decreases recovery time. Native BSC inocula, which included lichens and mosses, salvaged from gypsiferous soil habitats in Lake Mead National Recreation Area (LMNRA) in the eastern Mojave Desert were stored dry for two years and applied to disturbed soil after a road reconstruction in LMNRA and also used in laboratory experiments to test inoculation technique effectiveness. After 18 months, field results revealed positive relationships between inoculation and the presence of macroscopic BSC cover, cyanobacteria abundance, soil stability, and ammonium concentrations. Chlorophyll fluorescence monitoring of …

Elemental Contributions From Minor And Major Constituents Of Bone On The Separation Of Radiostrontium, Ashlee Rae Dailey

UNLV Theses, Dissertations, Professional Papers, and Capstones

While many methods exist to separate and analyze radionuclides from a variety of environmental matrices, the performance of all of these methods is often limited by other interfering constituents that are consistently found in most of these samples. The presence of such constituents can significantly reduce the recovery of the radioisotopes of interests and lead to incomplete separations.

Strontium has the same oxidation state and a similar atomic radius as calcium and is therefore readily able to substitute for calcium in lattice sites. This similarity in behavior leads to the preferential accumulation of strontium in newly formed bone. The study …

Morphological Features Of The Proximal Femur: Investigations Of Habitual Activities, Sex And Health In A Bronze Age Population From The Arabian Peninsula, Animikha Dutt

UNLV Theses, Dissertations, Professional Papers, and Capstones

Bronze Age sites on the Arabian Peninsula are relatively rare. The undisturbed nature of Tell Abraq, located in the United Arab Emirates, is significant since it represents one of the longest known occupied settlement sites dating from the 3rd millennium BC to the 1st century AD. This site has revealed an undisturbed communal tomb that was used for approximately 200 years (2200-2000 BC), housing commingled and disarticulated human remains of at least 286 adults and 127 subadults. The strategic coastal position of Tell Abraq, at the intersection of several major cultural centers, allowed its people to actively participate in world …

Characterization Of Beryllium As A Novel Agent To Study Cell Cycle Arrest And Cellular Senescence, Priyatham Gorjala

UNLV Theses, Dissertations, Professional Papers, and Capstones

Cancer cells evade senescence, apoptosis, and other constraints on proliferation, often via mutation of the p53 tumor suppressor gene (TP53). Normal human lung fibroblasts have been shown to enter premature senescence upon exposure to beryllium. In these cells, BeSO₄ stabilizes p53 protein, increases p21 gene expression, induces senescence-associated β-galactosidase activity and causes cell proliferation arrest. In the present study, we have investigated whether BeSO₄ is able to induce similar effects in cancer cells that have wildtype p53. We have demonstrated that beryllium salt at low concentration can induce molecular changes in the p53 signaling pathway leading to cell …

Anti-Germinants As A New Strategy To Prevent Clostridium Difficile Infections, Amber Janece Howerton

UNLV Theses, Dissertations, Professional Papers, and Capstones

Clostridium difficileinfections (CDI) have emerged as a leading cause of hospital-associated complications. CDI is the major cause of antibiotic-related cases of diarrhea and nearly all cases of pseudomembranous colitis. The infective form of C. difficileis the spore, a dormant and hardy structure that forms under stress. Germination of C. difficile spores into toxin producing bacteria in the GI tract of susceptible patients is the first step in CDI establishment. Patient susceptibility occurs with a disruption of the natural gut microbiota by broad-spectrum antibiotics. Antibiotic treatments usually resolve CDI but refractory cases are on the rise. Of great concern is the …

Exploring Reasons Why Men And Women Refrain From Sex Despite Desire, Alessandra Lanti

UNLV Theses, Dissertations, Professional Papers, and Capstones

Sexual behavior has been found to be an unreliable referent for sexual desire. Numerous studies have found that sexual activity is motivated by a range of non-desire related factors, from the promotion of intimacy to the seeking of new experiences. Sexual desire may also be an unreliable predictor of sexual activity. There is a dearth of research, however, on the reasons why individuals choose not to have sex despite the presence of desire for a willing partner. The main aim of this study is to qualitatively investigate the reasons why people refrain from sex when they feel desire for a …

Dreissena Rostiformis Bugensis: Desiccation Of Adult Quagga Mussels Found In Lake Mead As A Preventive Measure Against Overland Dispersal In The Western United States, Matthew Kappel

UNLV Theses, Dissertations, Professional Papers, and Capstones

The expansion of civilization across all borders of the world has proven to affect major components of ecosystems. Since the introduction and establishment of the aquatic invasive species (AIS),Dreissena rostiformis bugensis, commonly known as the quagga mussel, into the United States there has been an extensive amount of time and money spent on controlling and preventing their expansion across the United States. The quagga mussel is of major concern because of its ability to disrupt the ecological communities in previously non-infested bodies of water, which may cause a loss in biodiversity and effect environmental health. The quagga mussel has spread …

A Forensic Identification Utility To Create Facial Approximations Using Cone-Beam Computed Tomography Of 100 Hispanic Females: A Pilot Study, Behzad Nejat

UNLV Theses, Dissertations, Professional Papers, and Capstones

Introduction:Estimation of facial soft tissue appearance from human skeletal remains is often necessary in forensic identification. This process has been referred to as facial reconstruction or facial approximation and is a branch of forensic facial anthropology. Original methods for facial approximation originated in nineteenth century Europe and consisted of artists shaping clay over skull models using average soft tissue depths measured in cadavers. The last two decades have introduced numerous computerized techniques that have digitized this process while attempting to accurately and objectively define the relationship between a skull and its overlying soft tissue. This pilot study describes a method …

The Abundance And Distribution Pattern Of Quagga Mussels In The Las Vegas Bay Of Lake Mead, Nevada And Potential Correlation With Environmental Parameters, Scott Rainville

UNLV Theses, Dissertations, Professional Papers, and Capstones

The non-native quagga mussel [Dreissena bugensis (Andrusov, 1897)] was initially discovered in Boulder Basin of Lake Mead, Nevada-Arizona on January 6, 2007. This occurrence marked the first biological invasion of dreissenid mussels in the Western U.S., following a significant North American range expansion of invasive quagga mussels from populations that invaded and colonized the Great Lakes Region in the Northeastern U.S. during 1991. This nonindigenous mollusk species quickly spread from Boulder Basin and became established throughout the entire reservoir by the end of 2007, with the exception of the inner Las Vegas Bay. There was an apparent absence of settled …

The Study Of Nitrogen Sources In The Municipal Wells Of Cedar Falls, Iowa, Alison Renee Schell

Honors Program Theses

Groundwater nitrate contamination has been a persistent concern in the drinking water of Cedar Falls, Iowa. Identifying the source of the relatively high nitrates in Cedar Falls Municipal Well 3 is the primary focus of this investigation. Although none of the municipal wells have exceeded the maximum contaminant level for nitrogen ( 45 ppm N 03), the purpose of this project is to investigate the general drinking water quality in the area. To identify the source of the nitrate contamination, groundwater samples from four municipal wells, surface water samples from three sites on the Cedar River, and soil from twelve …

The Medieval Dark Horse: Challenge And Reward In The Middle English Lyric, Andrew S. Marvin

English Faculty Publications

“The Medieval Dark Horse: Challenge and Reward in the Middle English Lyric” explores the genre’s history and literary merits while addressing the question of why this valuable and extensive body of literature has largely gone untapped by scholars.

The introductory sections detail the historical and modern contexts of the lyric, including the state of scholarship, manuscripts, editions, dating issues, purpose, audience, types of lyrics, and themes. This background informs a discussion of the genre’s difficulties and offers solutions with which to counter them. Close readings of eight poems are included to exemplify the lyric’s thematic range, stylistic diversity, and literary …

Effective Computer Programming Instruction For Pre-University Albanian Students, Robert Mccloud, Ardiana Sula

School of Computer Science & Engineering Faculty Publications

The relationship between pre-university students and technology is frequently overrated. While we receive glowing reports about how young people are knowledgeable about computers, the truth is that their knowledge is typically about computer content and the manipulation of applications. Young students too often treat the actual programming and understanding of computers as a sort of magical mystery.

In this paper we look at a new Albanian initiative to identify and nurture the most talented of our pre-university students. In particular we look at contributions to the goal of making Albanians the most talented programmers in this area of Europe.

The …

Taxonomy Of Phanaeus Revisited: Revised Keys To And Comments On Species Of The New World Dung Beetle Genus Phanaeus Macleay, 1819 (Coleoptera: Scarabaeidae: Scarabaeinae: Phanaeini), W. D. Edmonds, J. Zídek

Insecta Mundi

The purpose of this paper is to reassess the taxonomy of Phanaeus MacLeay (Coleoptera: Scarabaeidae) to accommodate new taxa and changes in taxonomic opinion since the publication of Edmonds’ 1994 revision of the genus. The two subgenera and 13 species groups established by Edmonds (1994) remain unchanged. A revised set of keys with accompanying comments and illustrations separates 54 recognized valid species. Seven recently described valid species are incorporated into the revised classification: Phanaeus blackalleri Delgado-Castillo, 1991; P. bordoni Arnaud, 1996; P. changdiazi Kohlmann and Solís, 2001; P. lecourti Arnaud, 2000; P. martinezorum Arnaud, 2000; P. yecoraensis Edmonds, 2004; and …

Radio Direction Finding Network Receiver Design For Low-Cost Public Service Applications, Marcel Colman Eric Stieber

Master's Theses

A low-cost radio direction finding (RDF) VHF receiver has been investigated for development into a radio direction finding network (RDFN) with a particular focus towards public service and commercial asset tracking applications. The primary design criteria were reproducibility, low-cost, and simplicity such that public service and volunteer organizations can benefit from the technology. Two receiver designs were built and tested to allow for comparison of practicality, cost, and accuracy. A pseudo-Doppler RDF and a time difference of arrival (TDOA) receiver were built as proof-of-concept for a system design based on commercial off-the-shelf (COTS) components. The pseudo-Doppler system is a less …

Controlling Nanoparticle Dispersion For Nanoscopic Self-Assembly, Nathan S. Starkweather

Master's Theses

Nanotechnology is the manipulation of matter and devices on the nanometer scale. Below the critical dimension length of 100nm, materials begin to display vastly different properties than their macro- or micro- scale counterparts. The exotic properties of nanomaterials may trigger the start of a new technological revolution, similar to the electronics revolution of the late 20^th century. Current applications of nanotechnology primarily make use of nanoparticles in bulk, often being made into composites or mixtures. While these materials have fantastic properties, organization of nano and microstructures of nanoparticles may allow the development of novel devices with many unique properties. …

Fleeing East From Indian Country: State V. Eriksen And Tribal Inherent Sovereign Authority To Continue Cross-Jurisdictional Fresh Pursuit, Kevin Naud Jr.

Washington Law Review

In State v. Eriksen, the Washington State Supreme Court held that Indian tribes do not possess the inherent sovereign authority to continue cross-jurisdictional fresh pursuit and detain a non-Indian who violated the law on reservation land. This Comment argues the Eriksen Court’s reliance on RCW 10.92.020 is misplaced. RCW 10.92.020 is irrelevant to a consideration of sovereign authority. States do not have the authority to unilaterally define tribal power. A tribe retains sovereign powers not taken by Congress, given away in a treaty, or removed by implication of its dependent status. The Eriksen Court also misinterpreted the state statute …