Digital Commons Network^™

Juna2012, Robert Kelly

Robert Kelly Manuscripts

From June 2012 Robert Kelly Archive

Junj2012, Robert Kelly

Robert Kelly Manuscripts

From June 2012 Robert Kelly Archive

Juni2012, Robert Kelly

Robert Kelly Manuscripts

From June 2012 Robert Kelly Archive

Glutathione-Mediated Neuroprotection Against Methylmercury Neurotoxicity In Cortical Culture Is Dependent On Mrp1, Travis Rush, Xiaoqian Liu, Andrew B. Nowakowski, David H. Petering, Doug Lobner

Biomedical Sciences Faculty Research and Publications

Methylmercury (MeHg) exposure at high concentrations poses significant neurotoxic threat to humans worldwide. The present study investigated the mechanisms of glutathione-mediated attenuation of MeHg neurotoxicity in primary cortical culture. MeHg (5 μM) caused depletion of mono- and disulfide glutathione in neuronal, glial and mixed cultures. Supplementation with exogenous glutathione, specifically glutathione monoethyl ester (GSHME) protected against the MeHg induced neuronal death. MeHg caused increased reactive oxygen species (ROS) formation measured by dichlorodihydrofluorescein (DCF) fluorescence with an early increase at 30 min and a late increase at 6 h. This oxidative stress was prevented by the presence of either GSHME or …

The Relation Among Essential Habitat, Ocean Acidification, And Calcification On The Nantucket Bay Scallop (Argopecten Irradians), Bryanna Joy Broadaway

Graduate Doctoral Dissertations

The relation among essential habitat, ocean acidification, and calcification in Argopecten irradians (Lamarck 1819) was examined through field and laboratory research. Three major questions were addressed: 1) What habitat conditions are associated with abundant populations of bay scallops in Nantucket Harbor? 2) How might future predictions of ocean pH decline affect the biomineralization of shell by bay scallop across juvenile and adult life stages? 3) Are there biochemical indicators that can inform our understanding on how the bay scallop may cope with ocean acidifying events? Elemental fingerprinting of adult and juvenile Nantucket bay scallop shells, A. irradians, revealed distinct element/Ca …

Management Of Land Use Land Cover Through The Application Of Remote Sensing, Geographic Information Systems And Simulation, Praveen Jha

Graduate Doctoral Dissertations

Deforestation and degradation of forest areas, including those in the Protected Areas (PAs), are major concerns in India. There were 2 broad objectives of the study: the technological objective pertained to the development of state-of-art programs that could serve as Decision Support Systems while finalizing plans and policy interventions, while the other objective aimed at generating geo-spatial data in 2 PAs. A part of the Eastern Himalaya biodiversity hotspot, Manas Tiger Reserve (MTR), Assam, India having an area of 2837.12 sq km and an important part of Rajaji-Corbett Tiger Conservation Unit, Rajaji National Park (RNP), Uttarakhand, India, having an area …

The Impact Of Mindfulness On Exposure And Extinction Processes In Social Anxiety, Michael Treanor

Graduate Doctoral Dissertations

The present study sought to examine the potential impact of brief mindfulness inductions to enhance exposure and extinction processes in social anxiety. Mindfulness may enhance extinction through increased awareness of multiple conditioned excitors (thereby "overpredicting" the occurrence of an aversive outcome) or by acting as a retrieval cue to mitigate return of fear. Twenty-two participants high in social anxiety were recruited to participate in a series of massed exposures. Latent growth curve analyses revealed that participants who received mindfulness inductions prior to exposure procedures demonstrated enhanced extinction learning as measured by expectancy ratings, but not when measured by distress, state …

The Effects Of Gesture-Based Learning With Virtual Reality On Counting Ability For Children With Cerebral Palsy, Shwu-Ling Lee

Journal of Educational Technology Development and Exchange (JETDE)

This study investigated the effects of gesture-based learning with virtual reality (GBLVR) on the counting ability of three children with Cerebral Palsy (CP). Those elected were the children who had difficulty with counting skills in the classroom. By attending GBLVR math courses, children with CP learned counting numbers from 1 to 10 intuitively by moving their body and interacting with the design made for them. The single-subject experimental design within the multiple probe design across subjects was used to evaluate the effects. Virtual Reality Gesture-based Learning was the independent variable; the score from the Counting Ability was the dependent variable. …

Table Of Contents, Depaul College Of Law

DePaul Business & Commercial Law Journal

No abstract provided.

Genetic Contributions To The Midsagittal Area Of The Corpus Callosum, Kimberley A. Phillips, J. Rogers, E. A. Barrett, D. C. Glahn, P. Kochunov

Psychology Faculty Research

The degree to which genes and environment determine variations in brain structure and function is fundamentally important to understanding normal and disease-related patterns of neural organization and activity. We studied genetic contributions to the midsagittal area of the corpus callosum (CC) in pedigreed baboons (68 males, 112 females) to replicate findings of high genetic contribution to that area of the CC reported in humans, and to determine if the heritability of the CC midsagittal area in adults was modulated by fetal development rate. Measurements of callosal area were obtained from high-resolution MRI scans. Heritability was estimated from pedigree-based maximum likelihood …

Low-Carbon-Emissions Standards And The Wto: Do California Measures Targeting Greenhouse Gas Emissions Discriminate Against Canadian Oil

UBC Law Review

No abstract provided.

Global Technology Initiative At San Jose State University: Results Of Seven Years Of An International Experience For Students, Belle Wei, Patricia Backer, Wenchiang Chung, Andrew Wood

Faculty Publications

For XXX students to thrive in the highly competitive global economy, it is critical to develop international perspectives and knowledge. The $1 million Global Technology Initiative (GTI), established in 2004, provides SJSU students with an opportunity to gain a global perspective of the world by learning about technology and business developments in the Asia Pacific region. GTI donors are high-tech business leaders with strong business ties in Silicon Valley and the Asia Pacific region. Given the current trend of engineering globalization in the global economy, particularly the trend of outsourcing Silicon Valley manufacturing, development, and design work to foreign countries, …

Characterization Of Muscle Spindle Afferents In The Adult Mouse Using An In Vitro Muscle-Nerve Preparation, Katherine Wilkinson, H. E. Kloefkorn, S. Hochman

Faculty Publications, Biological Sciences

We utilized an in vitro adult mouse extensor digitorum longus (EDL) nerve-attached preparation to characterize the responses of muscle spindle afferents to ramp-and-hold stretch and sinusoidal vibratory stimuli. Responses were measured at both room (24°C) and muscle body temperature (34°C). Muscle spindle afferent static firing frequencies increased linearly in response to increasing stretch lengths to accurately encode the magnitude of muscle stretch (tested at 2.5%, 5% and 7.5% of resting length [Lo]). Peak firing frequency increased with ramp speeds (20% Lo/sec, 40% Lo/sec, and 60% Lo/sec). As a population, muscle spindle afferents could entrain 1:1 to sinusoidal vibrations throughout the …

Light Field And Water Clarity Simulation Of Natural Environments In Laboratory Conditions, Shachak Pe'eri, Glenn T. Shwaery

Center for Coastal and Ocean Mapping

Simulation of natural oceanic conditions in a laboratory setting is a challenging task, especially when that environment can be miles away. We present an attempt to replicate the solar radiation expected at different latitudes with varying water clarity conditions up to 30 m in depth using a 2.5 m deep engineering tank at the University of New Hampshire. The goals of the study were: 1) to configure an underwater light source that produced an irradiance spectrum similar to natural daylight with the sun at zenith and at 60° under clear atmospheric conditions, and 2) to monitor water clarity as a …

A Comparison Of Topical Menthol To Ice On Pain, Evoked Tetanic And Voluntary Force During Delayed Onset Muscle Soreness, Pramod Johar, Varun Grover, Robert V. Topp, David G. Behm

College of Nursing Faculty Research and Publications

Purpose/Background: Pain can adversely affect muscle functioning by inhibiting muscle contractions. Delayed onset muscle soreness was used as a tool to ascertain whether a topical menthol-based analgesic or ice was more effective at reducing pain and permitting greater muscular voluntary and evoked force. Methods: Sixteen subjects were randomized to receive either a topical gel containing 3.5% menthol or topical application of ice to the non-dominant elbow flexors two days following the performance of an exercise designed to induce muscle soreness. Two days later, DOMS discomfort was treated with a menthol based analgesic or ice. Maximum voluntary contractions and evoked tetanic …

Hydraulically Driven Mechanical Representation Of A Biological System, Andrea Argouarch, Michael Mceachern, Brandon Parham

Biomedical Engineering

No abstract provided.

Development Of A Blood Flow Measurement Protocol Using Particle Image Velocimetry, Jennifer Chi-Ying Go

Biomedical Engineering

Peripheral Arterial Occlusive Disease (PAOD) is an acquired inflammatory disease where a peripheral artery becomes occluded due to the buildup of atherosclerotic plaques. In patients that possess collateral arteries, an occlusion can lead to shear induced outward remodeling, arteriogenesis, of these collaterals, partially restoring blood flow. However, newly remodeled collaterals exhibit reduced functional vasodilation, which may impair normal activity, such as ambulation. To model chronic ischemia and arteriogenesis in collaterals, a femoral artery ligation in a murine hindlimb is commonly performed. Previous efforts by our group involved measurements of collateral artery diameter to assess the impact of arteriogenesis on functional …

Development And Characterization Of Plga And Eptfe Blood Vessel Mimics Using Gene Expression Analysis, Michael Gibbons, Sarah Ur

Biomedical Engineering

Tissue engineered blood vessels (TEBV’s) have the potential to act not only as a replacement for diseased vessels, but also as a testing platform for intravascular devices such as stents. To this end, the goal of this study was to develop protocols for the construction of TEBV’s composed of human vascular cells and either expanded polytetrafluoroethylene (ePTFE) or poly-lactic-co-glycolic acid (PLGA), as well as a protocol for gene expression in those TEBV’s. Initial experiments involved only human umbilical vein endothelial cells (HUVEC’s), but after low cell confluency and spreading in single-sodded vessels a second cell type, human umbilical vein smooth …

Gsp And Development: Increasing The Effectiveness Of Nonreciprocal Preferences, Matthew G. Snyder

Michigan Journal of International Law

The intellectual foundations of nonreciprocal preferences were first laid out in the 1960s, as several scholars noted developing countries' increasing reliance on highly volatile, low-value-added exports like agricultural and mineral commodities. The Generalized System of Preferences (GSP), which became the mechanism for implementing nonreciprocal preferential market access, was developed in this context. GSP was envisioned as part of a larger development strategy that included import-substitution policies, infant industry protection, and preferential access to developed countries' markets. As GSP granted preferential access over World Trade Organization (WTO) most favored nation (MFN) rates, development economists anticipated that it would provide developing countries' …

Ambitions Of A Global City: Arts, Culture And Creative Economy In 'Post-Crisis' Singapore, Lily Kong

Research Collection School of Social Sciences

This paper chronicles some of the key policies pertaining to the arts and culture in post-independent Singapore. A brief summary is first provided of the early (1960s and 1970s) cultural policy focusing on the harnessing of arts and culture for nation-building purposes, followed by the subsequent (1980s) recognition that the arts and culture had tourist dollar potential. The paper then expands on the cultural/creative economy policy of the 2000s, in which arts, heritage, media and design are recognized for their economic value (beyond their role in tourism to include their export value and their importance in attracting global workers). The …

The Antihero In Popular Culture: A Life History Theory Of The Dark Triad, Peter K. Jonason, Gregory D. Webster, David P. Schmitt, Norman P. Li, Laura Crysel

Research Collection School of Social Sciences

The Dark Triad of personality is composed of narcissism, psychopathy, and Machiavellianism. Despite the common belief that these traits are undesirable, the media is awash with characters that embody the Dark Triad. Characters like Gregory House, M.D., Batman (a.k.a. the Dark Knight), and James BOND all embody these traits and are some of the most popular media franchises today. As entertaining as these characters are, they provide us with a window into the dark side of human nature. Instead of treating the dark side of human nature as inherently maladaptive, we provide an alternative view that, despite their costs, traits …

Rickettsia Felis In Ctenocephalides Felis From Guatemala And Costa Rica, Adriana Troyo, Danilo Alvarez, Lizeth Taylor, Gabriela Abdalla, Olger Calderon-Arguedas, Maria L. Zambrano, Gregory A. Dasch, Kim A. Lindblade, Laya Hun, Marina Eremeeva, Alejandra Estevez

Environmental Health Sciences: Faculty Publications

Rickettsia felis is an emerging human pathogen associated primarily with the cat flea Ctenocephalides felis. In this study, we investigated the presence of Rickettsia felis in C. felis from Guatemala and Costa Rica. Ctenocephalides felis were collected directly from dogs and cats, and analyzed by polymerase chain reaction for Rickettsia-specific fragments of 17-kDa protein, OmpA, and citrate synthase genes. Rickettsia DNA was detected in 64% (55 of 86) and 58% (47 of 81) of flea pools in Guatemala and Costa Rica, respectively. Sequencing of gltA fragments identified R. felis genotype URRWXCal2 in samples from both countries, and genotype Rf2125 in …

Harvesting The "Forbidden Fruit" Of Biotechnology Research: Genetic Engineering, International Law And The Patentability Of Higher Life Forms In Canada, Eugene C. Lim

Canadian Journal of Law and Technology

As the frontiers of science are constantly redefined by the emergence of new technology, patent law often has to struggle to keep pace with the changing conception of what constitutes a protectable “invention”. A key challenge facing patent law in the age of biotechnology lies in ascertaining the extent to which genetically engineered life forms should be protected. A major concern relates to whether such life forms should be excluded from patentability on grounds of ordre public, ethics and morality.

This article critically explores the extent to which patent law in Canada protects this “forbidden fruit” of biotechnological innovation, and …

Narrative Imagination: A Design Imperative, Robert Tully

Irish Journal of Academic Practice

Each generation entrusts the collective future to the next. Just like the oral traditions of our past continue to manifest in our consciousness, we need to tell stories today that will free the imagination. Designers in particular need to develop the ability to articulate the imagined possibilities that the narrative imagination can create. In order to appreciate the complexity of interactions that are occurring in a spatial or object orientated context we need to think about the imagination as a vehicle to discover and explore these new possibilities. To do this we need to enhance our capacity to access the …

Manure In The Bay: A Report On Industrial Animal Agriculture In Maryland And Pennsylvania, Rena I. Steinzor, Yee Huang

Faculty Scholarship

This report provides a substantive and detailed look at the concentrated animal feeding operations (CAFO) and other animal feeding operations (AFO) programs in Maryland and Pennsylvania, as well as a general overview of the federal CAFO program. The information in this report was gathered through publicly available resources as well as a series of interviews with agency officials and other individuals who work with the animal agricultural sector. This report identifies concrete and practical recommendations for improving how the waste generated by animal industrial agriculture is managed and controlled by EPA, the Maryland Department of Environment (MDE), and the Pennsylvania …

Thinking About The Gym: Greek Ideals, Newtonian Bodies, And Exercise In Early Eighteenth-Century England, Robert K. Batchelor

History: Faculty Publications

Revival of Greek ideas about exercise in the British and Irish Enlightenment by doctors led to a shift in understandings about the independent mind by establishing a relation between bodily and mental health. By the late 1730s, interest shifted away from mind and body and towards the sentiments and passions, which marked gender distinctions and held together national communities. Gilbert West’s writing about the Olympics in the 1740s indicated the difficulty in resolving tensions about exercise and sport as producing aristocratic distinction and violent passions as against their encouragement of healthy minds and civic virtue in the nation.

Sexual Liberty And Same-Sex Marriage: An Argument From Bisexuality, Michael Boucai

San Diego Law Review

This article proposes that same-sex marriage bans channel individuals, particularly bisexuals, into heterosexual relationship and relationships, impermissibly burdening sexual liberty interests protected under Lawrence v. Texas. A claim from sexual liberty departs dramatically from the legal paradigms and advocacy strategies that currently dictate the terms of constitutional debate on this issue. This article proceeds in four parts. Part II develops the legal argument that same-sex marriage bans are unconstitutional under Lawrence because they substantially burden the right to choose homosexual relations and relationships. Part III posits bisexuality, understood as dual-sex desire, as an illuminating perspective on the coerced heterosexuality of …

The Suitability Of Ground Date (Phoenix Dactylifera L.) Pits And Ghaf (Prosopis Cineraria L.) Pods As Horticultural Growth Media Or Soil Amendments, Saeed Khalifa Alshaali

Theses

The UAE and its neighboring countries are encountering scarcity of water resources and soil degradation due to salinization. The current over-exploitation of aquifers by the agricultural sector is a major concern for the government. Open field production of forage as a feed for camels, cows and small ruminants requires particularly high amounts of irrigation water. Greenhouse production of fodder might save water, but would require a suitable growth substrate that is readily available in the UAE, and ideally constitutes a palatable fodder itself. The objective of this study was to evaluate the suitability of ground D.pits and G.pods as growth …

Communication-Based Assessment Of Developmental Age For Young Children With Developmental Disabilities, Shari L. Deveney, Lesa Hoffman, Cynthia J. Cress

Department of Psychology: Faculty Publications

Purpose: In this study, the authors compared a multiple-domain strategy for assessing developmental age of young children with developmental disabilities who were at risk for long-term reliance on augmentative and alternative communication (AAC) with a communication-based strategy composed of receptive language and communication indices that may be less affected by physically challenging tasks than traditional developmental age scores.

Method: Participants were 42 children (age 9–27 months) with developmental disabilities and who were at risk for long-term reliance on AAC. Children were assessed longitudinally in their homes at 3 occasions over 18 months using multiple-domain and communication-based measures. Confirmatory factor analysis …

Microhabitat Selection By Bobcats In The Badlands And Black Hills Of South Dakota, Usa: A Comparison Of Prairie And Forested Habitats, Cory E. Mosby, Troy W. Grovenburg, Robert W. Klaver, Greg M. Schroeder, Lowell E. Schmitz, Jonathan A. Jenks

The Prairie Naturalist

An understanding of habitat selection is important for management of wildlife species. Although bobcat (Lynx rufus) resource selection has been addressed in many regions of the United States, little work has been conducted in the Northern Great Plains. From 2006–2008 we captured and radiocollared 20 bobcats in the Badlands (n = 10) and Black Hills (n = 10) regions of South Dakota. During the summers of 2008 and 2009 we collected habitat measurements at 349 (176 Badlands, 176 Black Hills) bobcat locations and 321 (148 Badlands, 173 Black Hills) random sites. Microhabitat characteristics at bobcat use sites varied with region …