Digital Commons Network^™

Approaches To The Study Of Neural Coding Of Sound Source Location And Sound Envelope In Real Environments, Shigeyuki Kuwada, Brian Bishop, Duck O. Kim

UCHC Articles - Research

The major functions of the auditory system are recognition (what is the sound) and localization (where is the sound). Although each of these has received considerable attention, rarely are they studied in combination. Furthermore, the stimuli used in the bulk of studies did not represent sound location in real environments and ignored the effects of reverberation. Another ignored dimension is the distance of a sound source. Finally, there is a scarcity of studies conducted in unanesthetized animals. We illustrate a set of efficient methods that overcome these shortcomings. We use the virtual auditory space method (VAS) to efficiently present sounds …

Loss Of Vascular Early Response Gene Reduces Edema Formation After Experimental Stroke, Fudong Liu, L C. Turtzo, Jun Li, Neer Zeevi, Louise D. Mccullough

UCHC Articles - Research

Vascular Early Response Gene (Verge) is an immediate early gene (IEG) that is up-regulated in endothelial cells in response to a number of stressors, including ischemic stroke. Endothelial cell lines that stably express Verge show enhanced permeability. Increased Verge expression has also been associated with blood brain barrier breakdown. In this study we investigated the role of Verge in ischemic injury induced by middle cerebral artery occlusion (MCAO) in both Verge knockout (KO) and wild type (WT) mice. Verge KO mice had significantly less cerebral edema formation after MCAO compared to WT mice. However, stroke outcome (infarct size and neurological …

Genomic Analysis Of Pterostilbene Predicts Its Antiproliferative Effects Against Pancreatic Cancer In Vitro And In Vivo, David W. Mcfadden

UCHC Articles - Research

Background

To investigate the inhibitory role of pterostilbene in pancreatic cancer, we conducted a genomic analysis of pterostilbene-treated pancreatic cancer cells. We also investigated the effect of pterostilbene upon the carcinogenic markers, manganese superoxide dismutase, cytochrome C, Smac/DIABLO, and STAT3 phosphorylation in vitro. The antiproliferative effects of pterostilbene were further evaluated in an in vivo model.

Methods

Pancreatic cancer cells were treated with pterostilbene and evaluated with DNA microarray analysis. Pterostilbenetreated cells were analyzed for cytochrome C, Smac/DIABLO, manganese superoxide dismutase (MnSOD)/antioxidant activity, and STAT3 phosphorylation using ELISA. Data were statistically analyzed using ANOVA. Pterostilbene was then administered to nude …

Primetimes Newsletter, Summer 2012, Office Of Lifespan Studies

PrimeTimes Newsletter

PrimeTimes is the newsletter of the Office of Lifespan Studies in the College of Science at Coastal Carolina University.

A Case For Cooperation Between The Environmental Protection Agency And The United States Department Of Agriculture In Order To Achieve Federal Environmental Quality Goals. National Pork Producers' Council V. Epa, James D. Boresi

Journal of Environmental and Sustainability Law

No abstract provided.

Environmental Justice Issues In Sustainable Development: Environmental Justice In The Renewable Energy Transition, Uma Outka

Journal of Environmental and Sustainability Law

No abstract provided.

Dam Complications In Senegal: How River Dams May Hurt More Than Help Vulnerable Populations In Water-Stressed Regions, Colleen Diessner

Journal of Environmental and Sustainability Law

No abstract provided.

Book Reviews

Swedish American Genealogist

No abstract provided.

Voldemort Tyrannos: Plato’S Tyrant In The Republic And The Wizarding World, Anne Collins Smith, Owen M. Smith

Faculty Publications

In the Harry Potter novel series, by J. K. Rowling, the character of Lord Voldemort is the dictatorial ruler of the Death Eaters and aspiring despot of the entire wizarding community. As such, he serves as an apt subject for the application of Plato’s portrait of the tyrant in Republic IX. The process of applying Plato to Voldemort, however, leads to an apparent anomaly, the resolution of which requires that we move beyond the Republic to the account of beauty presented by Plato in the Symposium. In doing so, we shall find that while Plato can help us to understand …

Agents Of Change: Three Women Who Made A Difference, Linda J. Lear '62

Reunion Addresses

No abstract provided.

Frecuencia De Leptospira Spp En Porcinos De Crianza Tecnificada Y De Traspatio Beneficiados En Dos Mataderos De Lima, Luis Anampa V., Hermelinda Rivera G., Nestor Falcon P., Mariluz Araínga, Mercy Ramirez V.

Journal Articles: Pharmacology & Experimental Neuroscience

The objective of this study was to determine the frequency of antibodies against Leptospira spp in pigs reared in five well-managed farms (n = 163) and from 11 backyard breeding (n = 133) owners in the valley Lima, Peru. Blood samples (n=296) were collected in two slaughterhouses for antibody detection against eight serovars of Leptospira by microaglutination test. The 85.8 ± 3.9% (254/296) of samples had antibodies against one or more serovars of Leptospira. . The 89.6 ± 4.7% (146/163) and 82.1 ± 6.5% (108/133) of samples from well-managed farms and from backyard breeding pigs showed antibodies against Leptospira spp. …

Software Engineering Education Needs More Engineering, A. Frank Ackerman, Ph.D., Sushil Acharua, D.Eng.

Computer Science & Software Engineering

To what extent is “software engineering” really “engineering” as this term is commonly understood? A hallmark of the products of the traditional engineering disciplines is trustworthiness based on dependability. But in his keynote presentation at ICSE 2006 Barry Boehm pointed out that individuals’, systems’, and peoples’ dependency on software is becoming increasingly critical, yet that dependability is generally not the top priority for software intensive system producers. Continuing in an uncharacteristic pessimistic vein, Professor Boehm said that this situation will likely continue until a major software-induced system catastrophe similar in impact to the 9/11 World Trade Center catastrophe stimulates action …

"Evo In The News": A Pedagogical Tool To Enhance Students' Perceptions Of The Relevance Of Evolutionary Biology, Lynn M. Infanti

Science Teaching - Dissertations

This investigation evaluated the effects of the use of the pedagogical tool "Evo in the News" on the attitudes toward and knowledge of biological evolution in a sample of undergraduate non-major biology students at a large, private research university. In addition, this study looked at the initial attitudes of the students and their knowledge of evolution before beginning a second semester introductory biology course. Both the initial attitudes and knowledge of the students and the gains in positive attitudes and knowledge were measured using the Evolutionary Attitudes and Literacy Survey (EALS). The goal of the research was to analyze potential …

The Effects Of Caffeine On Spatial Learning And Memory, Romina G. Cupo

Theses

No abstract provided.

Mandatory War In The State Of Israel & The Idf Code Of Ethics, Michal Fine

Theses

No abstract provided.

Fostering Academic And Social Growth In A Primary Literacy Workshop Classroom: "Restorying" Students With Negative Reputations, Jo Worthy, Annamary L. Consalvo, Treavor Bogard, Katie W. Russell

Teacher Education Faculty Publications

In most classrooms, there are students who have academic, behavioral, and/or interpersonal challenges that can disrupt the classroom community. In some cases, these challenges can build momentum, leading to a negative reputation or “story” that can follow the student throughout school. This academic, yearlong case study focused on Mae Graham, an exemplary teacher, and the cases of two students who began second grade with negative behavioral, emotional, and academic reputations from previous years in school. We describe how Mae “restoried” the students through personalized instruction and attention, classroom structure and curriculum, and social interactions in the classroom. We base restorying …

Vasa-Like Dead-Box Rna Helicases Of Schistosoma Mansoni, Danielle E. Skinner, Gabriel Rinaldi, Sutas Suttiprapa, Victoria H. Mann, Pablo Smircich, Alexis A. Cogswell, David L. Williams, Paul J. Brindley

Microbiology, Immunology, and Tropical Medicine Faculty Publications

Genome sequences are available for the human blood flukes, Schistosoma japonicum, S. mansoni and S. haematobium. Functional genomic approaches could aid in identifying the role and importance of these newly described schistosome genes. Transgenesis is established for functional genomics in model species, which can lead to gain- or loss-of-functions, facilitate vector-based RNA interference, and represents an effective forward genetics tool for insertional mutagenesis screens. Progress toward routine transgenesis in schistosomes might be expedited if germ cells could be reliably localized in cultured schistosomes. Vasa, a member of the ATP-dependent DEAD-box RNA helicase family, is a prototypic marker of …

Melanoma Induction By Ultraviolet A But Not Ultraviolet B Radiation Requires Melanin Pigment, Frances P. Noonan, M. Raza Zaidi, Agnieszka Wolnicka-Glubisz, Miriam R. Anver, Jesse Bahn, Anastas Popratiloff, +9 Additional Authors

Anatomy and Regenerative Biology Faculty Publications

Malignant melanoma of the skin (CMM) is associated with ultraviolet radiation exposure, but the mechanisms and even the wavelengths responsible are unclear. Here we use a mammalian model to investigate melanoma formed in response to precise spectrally defined ultraviolet wavelengths and biologically relevant doses. We show that melanoma induction by ultraviolet A (320–400 nm) requires the presence of melanin pigment and is associated with oxidative DNA damage within melanocytes. In contrast, ultraviolet B radiation (280–320 nm) initiates melanoma in a pigment-independent manner associated with direct ultraviolet B DNA damage. Thus, we identified two ultraviolet wavelength-dependent pathways for the induction of …

Summer 2012, Marisela Cadena-Smith

Connection

The Official Community Newsletter for Collin College Connection is the college's award-winning community newsletter published three times a year to inform members of the Collin County community about college news, awards, events, and more.

"Literal Translation" And The Materiality Of Language: Lu Xun As A Case, Wenjin Cui

Languages, Literatures & Cultures

With his insistence upon the literal rendering in Chinese of foreign texts, especially regarding syntax, Lu Xun’s understanding of “literal translation” strikes a rather distinct note in the modern Chinese literary scene. The intention behind this method, namely, the aim to “retain the tone of the original,” reveals a generative perception of language that takes language as not just the bearer of the already existent thought, but as the formative element of thought that has meaning in itself. This paper seeks to delineate the structural constitution of the materiality of language as grasped by Lu Xun. By comparing the notion …

A New Four Point Circular-Invariant Corner-Cutting Subdivision For Curve Design, Jian-Ao Lian

Applications and Applied Mathematics: An International Journal (AAM)

A 4-point nonlinear corner-cutting subdivision scheme is established. It is induced from a special C-shaped biarc circular spline structure. The scheme is circular-invariant and can be effectively applied to 2-dimensional (2D) data sets that are locally convex. The scheme is also extended adaptively to non-convex data. Explicit examples are demonstrated.

Chaosocial - A Social Media Platform For Social Movements, Nathanael Hughes

Liberal Arts and Engineering Studies

Recent Social Movements have increasingly used social media as a driving component in recruiting, developing the cause, and mobilizing people to action. Chaosocial is a web application that provides a layer of organization over social media, allowing organizations traditionally limited in ability to leverage social media to use it to strengthen their social movements.

Center For Food Safety, Summer 2012, University Of Arkansas (System). Division Of Agriculture. Center For Food Safety

Center for Food Safety

No abstract provided.

Understanding The Relationship Between Entrepreneurship Education, Experiential Learning And Business Ethics, Kathleen Farrell, Thomas Cooney, Christina Benson, Gary Palin

Conference papers

Recent cognitive research in entrepreneurship describes the entrepreneur as a ‘motivated tactician’, who can be characterized as a “fully engaged thinker who has multiple cognitive strategies available” (Haynie et al., 2010: p18), and the ability to shift and choose rapidly from among them based on specific goals, motives, needs and circumstances, leading to the ability to act (or not) in response to perceived entrepreneurial opportunities. The Association for Experiential Education broadly defines experiential education as: “a philosophy and methodology in which educators purposefully engage with learners in direct experience and focused reflection in order to increase knowledge, develop skills and …

Lessons Unlearned: The Legal And Policy Legacy Of The Bp Deepwater Horizon Spill, Mark Davis

Washington and Lee Journal of Energy, Climate, and the Environment

The explosion and blowout of the BP Deepwater Horizon well in the Gulf of Mexico dominated much of the news and public discussion during the late spring and summer of 2010. The size and scale of the blowout and its effects on people, communities, and the environment produced loud calls for deep changes in the nation’s energy and environmental laws and policies. While some things have changed, the wide ranging changes that many expected have not yet come to pass; indeed if anything the momentum has shifted to letting aggressive oil and gas development resume and to leave the fundamental …

Three Macalester Faculty To Participate In Acm-Mellon Sail Seminar, Macalester College

College Press Releases

No abstract provided.

Title Page

Journal of Environmental and Sustainability Law

No abstract provided.

Dual – Species Biofilm Formation By Shiga – Toxin Producing Escherichia Coli O157:H7 And O26:H11 Serotypes, Rong Wang, Norasak Kalchayanand, John W. Schmidt, Joseph M. Bosilevac

Roman L. Hruska U.S. Meat Animal Research Center: Reports

E. coli O26:H11 strains could outgrow O157:H7 companion strains in planktonic and biofilm phases, and also effectively compete with pre-colonized O157:H7 cells to establish themselves in mixed biofilms. E. coli O157:H7 strains were unable to displace preformed O26:H11 biofilms. Therefore, E. coli O26:H11 remains a potential risk in food safety.

Using Resistivity Arrays To Monitor Groundwater Impacts Near Runoff Holding Ponds, Roger A. Eigenberg, Bryan L. Woodbury

Roman L. Hruska U.S. Meat Animal Research Center: Reports

Mineral and organic salts from beef manure contained in precipitation runoff from feedyard pen surfaces can alter the conductivity properties of soil and water receiving it. Typically, holding ponds are constructed to control runoff from concentrated animal feeding operations. The integrity of these holding ponds has come under increased scrutiny since leakage has the potential to affect soil and groundwater quality. Traditionally, ponds are monitored by installing monitoring wells at key locations to evaluate the impact of these ponds on the environment. These monitoring wells are expensive and subject to ambiguous interpretation. A subsurface resistivity array was installed at a …

Seldon E. Bernstein Papers, The Jackson Laboratory

Personal Papers Collection

No abstract provided.