Digital Commons Network^™

Investigation Into The Mechanism Of Salicylate-Associated Genotypic Antibiotic Resistance In Staphylococcus Aureus, Nada Salah Helal

USF Tampa Graduate Theses and Dissertations

Growth of Staphylococcus aureus with the NSAID salicylate increases phenotypic resistance (SAPAR), and the frequency at which heritable resistance occurs to various antibiotics (SAGAR). This study describes the effect of salicylate on heritable and phenotypic resistance to a set of antibiotics for laboratory and multi-drug resistant strains of S. aureus and investigates the link between resistance and SAGAR. Drug gradient plates were used to determine phenotypic resistance to antibiotics targeting DNA replication, transcription, translation and the cell wall in the presence or absence of salicylate. To measure heritable resistance, mutation frequencies were determined for each antibiotic in the presence and …

Linguistics / Etymology - University Of South Florida, Lisa Zilinski, Sonia Lorenz

Data Curation Profiles Directory

The research project is centered on determining the evolving meaning of the term “polytechnic”. As a standard class assignment, freshman students will be required to execute video interviews of upper classmen to find out what they think “polytechnic” means. This assignment will be repeated with each group of incoming freshmen so that all students will have the opportunity to interview and be interviewed. By interviewing the students each year, the researchers will be able to understand the changing definition of the term “polytechnic” as the students progress through school. By comparing responses from differing freshmen classes, the researchers will be …

Volume 49, Number 42: June 06, 2012, University Of North Dakota

University Letter Archive

No abstract provided.

Transforming Growth Factor-Β Suppresses Metastasis In A Subset Of Human Colon Carcinoma Cells., Neka A.K. Simms, Ashwani Rajput, Elizabeth A. Sharratt, Melanie Ongchin, Carol A. Teggart, J. Wang, Michael G. Brattain

Journal Articles: Eppley Institute

BACKGROUND: TGFβ signaling has typically been associated with suppression of tumor initiation while the role it plays in metastasis is generally associated with progression of malignancy. However, we present evidence here for an anti-metastatic role of TGFβ signaling.

METHODS: To test the importance of TGFβ signaling to cell survival and metastasis we compared human colon carcinoma cell lines that are either non-tumorigenic with TGFβ response (FET), or tumorigenic with TGFβ response (FETα) or tumorigenic with abrogated TGFβ response via introduction of dominant negative TGFβRII (FETα/DN) and their ability to metastasize. Metastatic competency was assessed by orthotopic transplantation. Metastatic colony formation …

Pride & Passion Exhibit Final Report, Chad M. Kahl, Jan Johnson

Faculty and Staff Publications – Milner Library

Milner Library hosted the Pride & Passion: The African American Baseball Experience exhibit from March 28 - May 11, 2012. This final report was submitted to the American Library Association and the National Endowment for the Humanities.

Bacteriophages Phi Mr299-2 And Phi Nh-4 Can Eliminate Pseudomonas Aeruginosa In The Murine Lung And On Cystic Fibrosis Lung Airway Cells, Aidan Coffey, Et. Al.

Department of Biological Sciences Publications

Pseudomonas aeruginosa is a common cause of infection in the lungs of patients with cystic fibrosis (CF). In addition, biofilm formation and antibiotic resistance of Pseudomonas are major problems that can complicate antibiotic therapy. We evaluated the efficacy of using bacteriophages to kill the pathogen in both biofilms and in the murine lung. We isolated and characterized two phages from a local wastewater treatment plant, a myovirus (ϕNH-4) and a podovirus (ϕMR299-2). Both phages were active against clinical isolates of P. aeruginosa. Together, the two phages killed all 9 clinical isolate strains tested, including both mucoid and nonmucoid strains. An …

Towards A Better Specification Of The Store Environment Stimulus: An Augmented Stimulus-Organism-Response (Sor) Model That Captures Brand Expressiveness, John Murray

Conference proceedings

Abstract: This paper proposes an augmented SOR model which facilitates design/architect practitioners when they review store concepts. The paper contributes to the knowledge base of designers/architects when making deliberate brand expressions in development of the store environment. The global nature of the SOR model, it is argued, does not allow for discrimination between consumer interpretations of store brands; nor does it propose a realistic means of engaging design-architect practitioners at the concept proofing stage of development. This conceptual paper argues that retail branding studies benefit from inclusion of more flexible frameworks founded on separable and integral design-architecture and brand communicative …

Having To Manage: Oral Reflections Of Daily Food Provision From Working Class Women In Dublin's 1950, Tony Kiely

Dublin Gastronomy Symposium

No abstract provided.

Electroconvulsive Therapy: A Review Of Its Current Status, Tyler Kenning, Ranjnish Mago, Steven Huege, Kenneth Certa, Rodney Pelchat

Jefferson Journal of Psychiatry

This article presents an overview of the current knowledge and practice of ECT. It provides a brief history of the development of ECT followed by a discussion of the accepted indications for ECT in psychiatric practice, including major depression, bipolar disorder (mania and depression), and schizophrenia. Moreover, a description of the technique of performing ECT is given. Also examined are the use of ECT in medically ill patients and the risks associated with ECT. In conclusion, with the aid of advances in anesthesia and the delivery of ECT, electroconvulsive therapy is a safe and effective treatment of mood and psychotic …

Taking Stock: A Potted History Of The Material Life Of The Kitchen, Msry Colette Sheehan

Dublin Gastronomy Symposium

No abstract provided.

A Taste Of Faith: Experiments In Culinary Psychology, Edia Conole, Scott Wilson

Dublin Gastronomy Symposium

No abstract provided.

Refining Pleasures, Frank Armstrong

Dublin Gastronomy Symposium

No abstract provided.

Engraved In The Mind: The Significance Of Smell, Jane Levi

Dublin Gastronomy Symposium

No abstract provided.

Introduction, Donald Landry, William J. Christmas

Criticism

No abstract provided.

Some Avenues For Feeling, Adam Frank

Criticism

The Particulars of Rapture: An Aesthetics of the Affects (Charles Altieri)
Compassion: The Culture and Politics of an Emotion (ed. Lauren Berlant)
Disgust: The Theory and History of a Strong Sensation (Winfried Menninghaus)
Touching Feeling: Affect, Pedagogy, Performativity (Eve Kosofsky Sedgwick)

Intersections Of Science, Sensation, And Culture, Charles J. Stivale

Criticism

Parables for the Virtual: Movement, Affect, Sensation (Brian Massumi)

Introduction: Materia Media, Cannon Schmitt

Criticism

No abstract provided.

Book Reviews, Criticism Editors

Criticism

The Pursuit of Pleasure: Gender, Space and Architecture in Regency London (Jane Rendell) (Reviewed by Claire Nicolay, Loyola University Chicago)

Faulkner and the Politics of Reading (Karl F. Zender) (Reviewed by John Bassett, Clark University)

Perceiving Animals, Humans and Beasts in Early Modern English Culture (Erica Fudge) (Reviewed by Ron Broglio, Georgia Institute of Technology)

Cuisine & Traditions Rescue: An Historic Face About The Culinary Relationship Between Mexico And Ireland, Jose Bossuet Martinez

Dublin Gastronomy Symposium

No abstract provided.

An Investigation Of Nanos1 Function During Primordial Germ Cell Development In Xenopus Laevis., Fangfang Lai

Open Access Dissertations

Nanos is expressed in multipotent cells, stem cells, and primordial germ cells (PGCs) of organisms as diverse as jellyfish and humans. It functions together with Pumilio to translationally repress targeted mRNAs. Here we show by loss-of-function experiments that Xenopus Nanos1 is required to preserve PGC fate. Morpholino knockdown of maternal Nanos1 resulted in a striking decrease in PGCs and loss of germ cells from the gonads. Lineage tracing and TUNEL staining reveals that Nanos1 deficient PGCs fail to migrate out of the endoderm. They appear to undergo apoptosis rather than convert to normal endoderm. Whereas normal PGCs do not become …

Ndls Update 06/05/2012, Notre Dame Law School

NDLS Update

No abstract provided.

The Pseudomonas Syringae Hrpj Protein Controls The Secretion Of Type Iii Translocator Proteins And Has A Virulence Role Inside Plant Cells, Emerson Crabill, Andrew Karpisek, James R. Alfano

Center for Plant Science Innovation: Faculty Publications

The bacterial plant pathogen Pseudomonas syringae injects effector proteins into plant cells via a type III secretion system (T3SS), which is required for pathogenesis. The protein HrpJ is secreted by P. syringae and is required for a fully functional T3SS. A hrpJ mutant is non-pathogenic and cannot inject effectors into plant cells or secrete the harpin HrpZ1. Here we show that the hrpJ mutant also cannot secrete the harpins HrpW1 and HopAK1 or the translocator HrpK1, suggesting that these proteins are required in the translocation (injection) of effectors into plant cells. Complementation of the hrpJ mutant with secretion incompetent HrpJ …

High-Activity Mutants Of Butyrylcholinesterase For Cocaine Hydrolysis And Method Of Generating The Same, Chang-Guo Zhan, Hoon Cho, Hsin-Hsiung Tai

Pharmaceutical Sciences Faculty Patents

A novel computational method and generation of mutant butyrylcholinesterase for cocaine hydrolysis is provided. The method includes molecular modeling a possible BChE mutant and conducting molecular dynamics simulations and hybrid quantum mechanical/molecular mechanical calculations thereby providing a screening method of possible BChE mutants by predicting which mutant will lead to a more stable transition state for a rate determining step. Site-directed mutagenesis, protein expression, and protein activity is conducted for mutants determined computationally as being good candidates for possible BChE mutants, i.e., ones predicted to have higher catalytic efficiency as compared with wild-type BChE. In addition, mutants A199S/A328W/Y332G, A199S/F227A/A328W/Y332G, A199S/S287G/A328W/Y332G, …

Human Impact On Atolls Leads To Coral Loss And Community Homogenisation: A Modeling Study, Bernhard Riegl, Charles R. C. Sheppard, Samuel J. Purkis

Marine & Environmental Sciences Faculty Articles

We explore impacts on pristine atolls subjected to anthropogenic near-field (human habitation) and far-field (climate and environmental change) pressure. Using literature data of human impacts on reefs, we parameterize forecast models to evaluate trajectories in coral cover under impact scenarios that primarily act via recruitment and increased mortality of larger corals. From surveys across the Chagos, we investigate the regeneration dynamics of coral populations distant from human habitation after natural disturbances. Using a size-based mathematical model based on a time-series of coral community and population data from 1999–2006, we provide hind- and forecast data for coral population dynamics within lagoons …

Methods For Increasing Potency Of Adult Mesenchymal Stem Cells, Kiminobu Sugaya, Angel Alvarez

UCF Patents

Disclosed herein are methods and materials for producing a more developmentally potent cell from a less developmentally potent cell. Specifically exemplified herein are methods that comprise introducing an expressible dedifferentiating polynucleotide sequence into a less developmentally potent cell, wherein the transfected less developmentally potent cell becomes a more developmentally potent cell capable of differentiating to a less developmentally potent cell of its lineage of origin or a different lineage.

Mammalian Multipotent Stem Cells And Compositions, Methods Of Preparation And Methods Of Administration Thereof, Kiminobu Sugaya, Christopher Brannen, Xiajing Dong, Hojoong Kim, Jose Pulido, Tingyu Qu, Ankur Vaghani

UCF Patents

This invention provides methods for preparing novel mammalian multipotent stem cells (MSCs), compositions thereof, and methods of preparing and administering the cells.

State V. Sexton-Gwin Appellant's Brief Dckt. 39352

Idaho Supreme Court Records & Briefs, All

No abstract provided.

Sesquiterpene Synthase Gene And Protein, Joe Chappell, Bryan Greenhagen

Plant and Soil Sciences Faculty Patents

The invention relates to sesquiterpene synthases and methods for their production and use. Particularly, the invention provides nucleic acids comprising the nucleotide sequence of citrus valencene synthase (CVS) which codes for at least one CVS. The invention further provides nucleic acids comprising the nucleotide sequence coding for amino acid residues forming the tier 1 and tier 2 domains of CVS. The invention also provides for methods of making and using the nucleic acids and amino acids of the current invention.

Florida Sentinel Bulletin, June 5, 2012, Gwen Hayes

Florida Sentinel Bulletin Collection

The June 5, 2012, issue of the Florida Sentinel Bulletin.

"Nevermericans?": How Communication Issues Shape The Perceptions Of Self And The Perceptions Of American Identity Among The International Students, Lyudmyla Pustelnyk

Masters Theses

This study of Intercultural communication and identity uses Cultural Contracts theory and Narrative theory to explore how international students communicate about their understanding of self (identity) and how this understanding is influenced and changes during their studies in the United States. Research participants who have, or are currently studying in the U.S., from Eastern and Central European countries were interviewed about their communication experiences while in the U.S., resulting in different expressions of identity - in-between identity, feeling Americanized, global citizen, and crystallization of native identity - which developed as the result of their U.S. university studies. Their narratives also …