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Annual Report Of The Officers, Trustees, Boards, Committees And Agents For The Town Of Nottingham, New Hampshire For The Year Ending December 31, 2011., Nottingham Town Representatives

Nottingham, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.

The Cyborg Griffin: A Speculative Fiction Literary Journal, Hollins University

Cyborg Griffin: a Speculative Fiction Literary Journal

Notes:

copyrighted

Hollins Student Publication

Scope: short stories, artwork, poetry, essays, and comics

Paper copies shelved in University Archives.

Treml4, An Ig Superfamily Member, Mediates Presentation Of Several Antigens To T Cells In Vivo, Including Protective Immunity To Her2 Protein, Hiroaki Hemmi, Neeha Zaidi, Bei Wang

Publications

Members of the triggering expressed on myeloid cells (Trem) receptor family fine-tune inflammatory responses. We previously identified one of these receptors, called Treml4, expressed mainly in the spleen, as well as at high levels by CD8α ⁺ dendritic cells and macrophages. Like other Trem family members, Treml4 has an Ig-like extracellular domain and a short cytoplasmic tail that associates with the adaptor DAP12. To follow up on our initial results that Treml4-Fc fusion proteins bind necrotic cells, we generated a knockout mouse to assess the role of Treml4 in the uptake and presentation of dying cells in vivo. Loss of …

Targeting Of The Non-Mutated Tumor Antigen Her2/Neu To Mature Dendritic Cells Induces An Integrated Immune Response That Protects Against Breast Cancer In Mice, Bei Wang, Neeha Zaidi, Lishen He

Publications

Introduction: Given their relative simplicity of manufacture and ability to be injected repeatedly, vaccines in a protein format are attractive for breast and other cancers. However, soluble human epidermal growth factor receptor (HER2)/neu protein as a vaccine has not been immunogenic. When protein is directly targeted to antigen uptake receptors, such as DEC205 (DEC), efficient processing and presentation of antigen take place. The aim of this study was to determine the immunogenicity of a HER2 protein vaccine that directly targets to DEC ⁺dendritic cells (DCs) in a mouse breast cancer model.Methods: We genetically engineered the HER2 extracellular domain into …

Strategy For Identifying Dendritic Cell-Processed Cd4+ T Cell Epitopes From The Hiv Gag P24 Protein, Leonia Bozzacco, Haiqiang Yu, Jörn Dengjel

Publications

Mass Spectrometry (MS) is becoming a preferred method to identify class I and class II peptides presented on major histocompability complexes (MHC) on antigen presenting cells (APC). We describe a combined computational and MS approach to identify exogenous MHC II peptides presented on mouse spleen dendritic cells (DCs). This approach enables rapid, effective screening of a large number of possible peptides by a computer-assisted strategy that utilizes the extraordinary human ability for pattern recognition. To test the efficacy of the approach, a mixture of epitope peptide mimics (mimetopes) from HIV gag p24 sequence were added exogenously to Fms-like tyrosine kinase …

Decisions About Dendritic Cells: Past, Present, And Future, Ralph M. Steinman

Publications

A properly functioning adaptive immune system signifies the best features of life. It is diverse beyond compare, tolerant without fail, and capable of behaving appropriately with a myriad of infections and other challenges. Dendritic cells are required to explain how this remarkable system is energized and directed. I frame this article in terms of the major decisions that my colleagues and I have made in dendritic cell science and some of the guiding themes at the time the decisions were made. As a result of progress worldwide, there is now evidence of a central role for dendritic cells in initiating …

Dll4-Notch Signaling In Flt3-Independent Dendritic Cell Development And Autoimmunity In Mice, Fabienne Billiard, Camille Lobry, Guillaume Darrasse-Jèze

Publications

Delta-like ligand 4 (Dll4)-Notch signaling is essential for T cell development and alternative thymic lineage decisions. How Dll4-Notch signaling affects pro-T cell fate and thymic dendritic cell (tDC) development is unknown. We found that Dll4 pharmacological blockade induces accumulation of tDCs and CD4 ⁺CD25 ⁺FoxP3 ⁺ regulatory T cells (T _reg cells) in the thymic cortex. Both genetic inactivation models and anti-Dll4 antibody (Ab) treatment promote de novo natural T _reg cell expansion by a DC-dependent mechanism that requires major histocompatibility complex II expression on DCs. Anti-Dll4 treatment converts CD4 ^-CD8 ^-c-kit ⁺CD44 ⁺CD25 …

Msum Student Academic Conference, Minnesota State University Moorhead

Student Academic Conference Abstract Books

Minnesota State University Moorhead Student Academic Conference abstract book.

Trophic Cascades And Private Property: The Challenges Of A Regulatory Balancing Act And Lessons The Uk Can Learn From The Reintroduction Of The American Gray Wolf, Whitney G. Stohr

University of Baltimore Journal of Land and Development

No abstract provided.

Superweeds And Suspect Seeds: Does The Genetically-Engineered Crop Deregulation Process Put American Agriculture At Risk?, Margaret Sova Mccabe

University of Baltimore Journal of Land and Development

No abstract provided.

Strictly Liable Landlords Could Mean The Pound For Pit Bulls, Caitlin Biggins

University of Baltimore Journal of Land and Development

No abstract provided.

Review Of Anat Pick, Creaturely Poetics; Mark Payne, The Animal Part; Susan Mchugh, Animal Stories, Carlo Salzani

Bryn Mawr Review of Comparative Literature

Anat Pick, Creaturely Poetics: Animality and Vulnerability in Literature and Film. New York: Columbia University Press, 2011. 249 pp. ISBN 9780231147873; Mark Payne, The Animal Part: Human and Other Animals in the Poetic Imagination. Chicago: University of Chicago Press, 2010. 164 pp. ISBN 9780226650845; Susan McHugh, Animal Stories: Narrating across Species Lines. Minneapolis: University of Minnesota Press, 2011. 336 pp. ISBN 9780816670338 (paper).

Transboundary Management Of Transitional Waters – Code Of Conduct And Good Practice Examples, Henrik Nilsson, Ramūnas Povilanskas, Nardine Stybel

ARTWEI

Transitional waters have the ecological peculiarity of being both very fragile and resilient at the same time. The degradation of the transitional waters and the decline of their economic value arise from the excessive use of the resources, external input of pollutants mostly brought by large tributaries and from the mismanagement of the adjacent areas. The EU Water Framework Directive has accelerated the transboundary co-operation and development of spatially integrative management approaches in the south Baltic transitional waters. A high-level political committment in countries sharing a transitional water body, a professional agency, a stakeholders‘ forum and regular funding is the …

Berita Autumn 2012, Derek Heng

Berita

Table of Contents

Chair’s Address...2

Editor’s Foreword...3

Members’ Updates...4

John A. Lent Prize...5

Breaking from the Past? The 2012 Hougang By-­‐Elections ...7

Book Review: Student Activism in Malaysia...12

Reframing the Singaporean Political Discourse...16

Limits of the Developmental State...20

Brief For Prof. Leslie C. Griffin Et Al. As Amici Curiae In Support Of Respondents, Hosanna-Tabor Evangelical Lutheran Church And School V. E.E.O.C., Leslie C. Griffin

Supreme Court Briefs

No abstract provided.

The Igeneration: Technology Guidelines For Parents And Teachers, Karen A. Waldron

Education Faculty Research

Ah, children and technology! At times, it can be overwhelming for families and educators to sort out the usefulness and danger of technological innovations in the hands of our youth. Often naïve of the outcomes of sending out personal information and photos, they worry us with their lack of understanding of consequences of “viral” messages and videos or about how much information they can safely share when others are willing to exploit their innocence. Yet when all else fails, we ask a 10-yearold for help in solving a computer problem and are usually astonished at the confidence and competence demonstrated …

Stone Oak Park Exploration: 5th Grade, Canyon Ridge Elementary School (San Antonio, Tex.)

Stone Oak Park UbD Units

Topic: Changes Over Time (erosion, weathering, deposition) and Plant Adaptations

Stone Oak Park Exploration: 4th Grade, Canyon Ridge Elementary School (San Antonio, Tex.)

Stone Oak Park UbD Units

Topic: Plant Adaptations, Weathering, Erosion, Food Webs

Aquilegia, Vol. 36 No. 2, 2012 Annual Meeting Issue, Newsletter Of The Colorado Native Plant Society, Bob Henry

Aquilegia - Colorado Native Plant Society

No abstract provided.

Toxicological Assessment Of Intra‐Tracheal Instilled Nanoceria On Kidneys Of Sprague‐Dawley Rats, Geeta Nandyala

Theses, Dissertations and Capstones

Recent studies suggest that use of nanoceria in industry is associated with increased risk of human and environmental exposure. How inhaled nanoceria might affect the kidneys is not yet known. To investigate this possibility, Sprague Dawley rats were exposed to a single dose of 7mg/kg body weight cerium oxide nanoparticles by intratracheal instillation. Animals were sacrificed at day 1, 3, 14, or 28 days after exposure and the kidneys collected for histological and biochemical analysis. No significant difference was observed in kidney to body weight ratio between the different groups. Hematoxylin and eosin staining did not reveal any significant changes …

Diversity Of The Ohio River Bacterial Communities Using Next-Generation Sequencing Techniques, Emily Michele Anneken

Theses, Dissertations and Capstones

The ability to sequence bacterial genetic material directly from environmental samples has unlocked the field of metagenomics. Next-generation sequencing techniques, such as pyrosequencing, have been instrumental in providing knowledge about bacterial communities. This study focused on identifying the bacterial diversity of the Ohio River via pyrosequencing and compared the diversity of cultivable bacteria versus the entire river community. To ensure the maximum number of cultivable bacteria was obtained, cultures were grown on nonselective media and incubated at river temperature. Bacterial DNA was extracted, sequenced, and classified. The dominant phyla for the Ohio River included Cyanobacteria (38-66% of the total), Actinobacteria …

Mothers At Work: Reconstruction And Deconstruction Of Patriarchy In Gone With The Wind, Catherine Willa Staley

Theses, Dissertations and Capstones

In this thesis, I explore the performances of motherhood in Margaret Mitchell’s Gone with the Wind and how those performances conflict with culturally constructed expectations of that role. An analysis of Scarlett O’Hara and Melanie Wilkes, and how each woman compares to the South’s model for motherhood, reveals implications that extend beyond the novel’s Civil War setting to reveal the ongoing negotiation of modern readers still living within patriarchal conceptions of mothering. In Chapter 1, I outline the novel’s spectrum of motherhood, which is composed of characters who nurture and manage others. Each individual on that spectrum contributes to or …

The Effect Of Auditory Call Playback On Anuran Detection And Capture Rates, Derek Adam Bozzell

Theses, Dissertations and Capstones

Calls of male anurans during breeding seasons are species-specific identification tools. However, males cease calling after any nearby disturbance, including those of researchers. I proposed a variation on current methods that attempts to reduce this lag in calling after researcher-created disturbance by utilizing the propensity for competition in male frogs. I surveyed 14 breeding sites in Cabell and Wayne counties during the 2010 and 2011 breeding seasons. First, I used traditional visual encounter surveys (VESs). After using automated recording devices to gather site-specific recordings of calls of all species present, I conducted secondary VESs while playing these playlists over a …

Evaluation Of The Role Of Oxidative Stress, Inflammation And Apoptosis In The Pulmonary And The Hepatic Toxicity Induced By Cerium Oxide Nanoparticles Following Intratracheal Instillation In Male Sprague-Dawley Rats, Siva Krishna Nalabotu

Theses, Dissertations and Capstones

The field of nanotechnology is rapidly progressing with potential applications in the automobile, healthcare, electronics, cosmetics, textiles, information technology, and environmental sectors. Nanomaterials are engineered structures with at least one dimension of 100 nanometers or less. With increased applications of nanotechnology, there are increased chances of exposure to manufactured nanomaterials. Recent reports on the toxicity of engineered nanomaterials have given scientific and regulatory agencies concerns over the safety of nanomaterials. Specifically, the Organization for Economic Co-operation and Development (OECD) has identified fourteen high priority nanomaterials for study. Cerium oxide (CeO2) nanoparticles are one among the high priority group. Recent data …

Fueling Sport Performance: Increasing Awareness In Female Collegiate Vegetarian Athletes, Rachael Irene Marie Sofie

Theses, Dissertations and Capstones

Vegetarian diets, when well-planned out, have been shown to meet the needs of female athletes. Although the lifestyle provides many benefits, it does not come without risk. Women athletes, in particular, are of the greatest concern. Energy restriction is common among female collegiate athletes. Because athletes are already converting to and practicing a vegetarian lifestyle, it is necessary that athletes and related sport professionals become aware of the risks and benefits of a vegetarian lifestyle. By increasing knowledge among related personnel, athletes can use vegetarianism as a performance enhancer. Outlining possible implications of the lifestyle will allow female collegiate athletes …

Freshwater Mussel Populations Of The Monongahela River, Pa And Evaluation Of The Orsanco Copper Pole Substrate Sampling Technique Using G.I.S. Interpolation With Geometric Means, Jonathan Hart

Theses, Dissertations and Capstones

Large river studies for freshwater mussel populations and habitat in the Monongahela River within Pennsylvania have been almost non-existent over the past century. Aquatic diversity and water quality have been impaired in the Monongahela River since the Industrial Revolution and early impoundments were constructed to control the river. To date, there have been no thorough mussel population studies conducted on the Pennsylvanian Monongahela River proper since A.E. Ortmann in 1919. The mussel population accounts for this large river system are invaluable accounts of the aquatic condition of the Monongahela River. Mussel populations and habitat within the river have diminished drastically …

The Status And Distribution Of Invasive Crayfishes And Their Effects On Native Crayfish Communities In West Virginia, Casey David Swecker

Theses, Dissertations and Capstones

Introductions of non-native crayfish species have resulted in the global decline of native crayfish populations, including those in North America. The last large survey of crayfishes from West Virginia was in 1988 and 1989. In this thorough document Raymond Jezerinac, Whitney Stocker, and Donald Tarter identified three separate areas in West Virginia where non-native crayfish species have been introduced. One area is located in the Potomac River drainage in northeastern West Virginia commonly referred to as the eastern panhandle of the state. This is also the only drainage in West Virginia where the native spiny cheek crayfish (Orconectes limosus) occurs. …

A Local Radial Basis Function Method For The Numerical Solution Of Partial Differential Equations, Maggie Elizabeth Chenoweth

Theses, Dissertations and Capstones

Most traditional numerical methods for approximating the solutions of problems in science, engineering, and mathematics require the data to be arranged in a structured pattern and to be contained in a simply shaped region, such as a rectangle or circle. In many important applications, this severe restriction on structure cannot be met, and traditional numerical methods cannot be applied. In the 1970s, radial basis function (RBF) methods were developed to overcome the structure requirements of existing numerical methods. RBF methods are applicable with scattered data locations. As a result, the shape of the domain may be determined by the application …

The Detection Of Forest Structures In The Monongahela National Forest Using Lidar, Dominique Norman

Theses, Dissertations and Capstones

The mapping of structural elements of a forest is important for forestry management to provide a baseline for old and new-growth trees while providing height strata for a stand. These activities are important for the overall monitoring process which aids in the understanding of anthropogenic and natural disturbances. Height information recorded for each discrete point is key for the creation of canopy height, canopy surface, and canopy cover models. The aim of this study is to assess if LiDAR can be used to determine forest structures. Small footprint, leaf-off LiDAR data were obtained for the Monongahela National Forest, West Virginia. …

Examining Social Anxiety And Depression Among Excessive Online Gamers, Nathan Sharer

Theses, Dissertations and Capstones

The main purpose of this study was to examine the correlations between social anxiety, depression, and other psychological factors among online gamers in order to better understand the differences between excessive gamers (whose habits interfere with relationship, occupational, social, or health issues) and enthusiastic gamers (who spend much of their free time playing games but do not report any significant functional impairment as a result). A literature review revealed diverse conceptualizations of excessive gaming as well as differing opinions of what classifies gaming to be excessive/addicting/problematic, suggesting a need to more specifically analyze gaming habits in terms of coexisting pathology …