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Articles 108421 - 108450 of 108521
Full-Text Articles in Entire DC Network
Cellular Effects Of Knocking Down Expression Of Dynactin's P150glued Subunit, Joseph Praver
Cellular Effects Of Knocking Down Expression Of Dynactin's P150glued Subunit, Joseph Praver
Harriet L Wilkes Honors College Theses 2010 - 2019
Dynactin is made up of 11 different peptide units with a distinct ultrastructure consisting of a shoulder/sidearm complex and a rod-like domain. It functions as a cofactor for cytoplasmic dynein, assisting in the processes of long-range vesicle movements, microtubule anchoring, endomembrane localization, and mitotic progression. Previous studies have shown that dynactin binds to microtubules at the centrosome, keeping a radial arrangement during interphase. The p150Glued subunit contains two distinct microtubule-binding domains: CAP-Gly and Basic. While both of these sequences can interact with microtubules, CAP-Gly has a much greater affinity for binding to microtubules, suggesting that the two domains may be …
Ethnosexual Frontiers: Where Art Meets Race Within International Politics, Renata Rodriguez-Bozzetto
Ethnosexual Frontiers: Where Art Meets Race Within International Politics, Renata Rodriguez-Bozzetto
Harriet L Wilkes Honors College Theses 2010 - 2019
Since the economic crisis from 2007, an extensive debate matching unemployment and immigration has been central to conservative discourses. Although progressive organizations have been critical of the SB1070 law in Arizona for its pervasive racial profiling content, some individuals seem to ignore the strong history of legislation, cultural apparatus and social norms that were made to support white supremacy within the history of United States. As immigration comes to the American debate, various politics adopted by the United States towards South American countries have been ignored. My objective with this research is to take a closer look at the artistic …
An Animal Model Of Performance Enhancing Drugs And Catastrophic Interference, Akiva Rabinowitz
An Animal Model Of Performance Enhancing Drugs And Catastrophic Interference, Akiva Rabinowitz
Harriet L Wilkes Honors College Theses 2010 - 2019
The neural networks that underlie memory and learning are some of the most complex systems that scientists seek to describe. Recent research has demonstrated that drugs which increase synaptic plasticity possess the capacity to enhance memory. The question that the present study sought to address was whether it is possible that cognition-enhancing drugs might enhance some memories to the detriment of others. Mice of the C57BL/6J inbred strain were trained on the Morris water maze task. They were then transferred over to a second, similar, water maze and trained using either the cognition-enhancing drug apamin or saline injected intraperitoneally. A …
History Of Misunderstanding: The Colonization Of New Zealand, William Rumbold
History Of Misunderstanding: The Colonization Of New Zealand, William Rumbold
Harriet L Wilkes Honors College Theses 2010 - 2019
Through examination of first contact between the British Empire and the Maori natives of New Zealand, as well as the failed treaty attempt between the two, I aim to illustrate England’s role in the escalation of conflict between these two cultures. Although at first glance it appears that the war was an eventual escalation of previous tensions, I maintain that British officials in New Zealand had the resources and the knowledge to prevent the New Zealand land war. They used this knowledge to speed up the process of conquest. The British crown was trying to conquer the Maori through ambiguous …
Analysis Of Mutant Manganese-Superoxide Dismutase On The Lifespan Of Saccharomyces Cerevisiae"", Sarah Salem
Analysis Of Mutant Manganese-Superoxide Dismutase On The Lifespan Of Saccharomyces Cerevisiae"", Sarah Salem
Harriet L Wilkes Honors College Theses 2010 - 2019
Previously isolated mutants of the superoxide dismutase 2 gene (SOD2), selected for increased activity in E. coli, were transformed into yeast cells in order to observe their effects on aging. Polymerase chain reaction and DNA sequencing were used to confirm that the yeast incorporated the mutant form of the gene. The strains with mutant forms of the SOD2 gene were observed to have decreased growth rates compared to the unmutated strain. Lifespan analyses were then conducted in order to see if yeast with mutant versions of SOD2 had lifespans that differed significantly from those with the unmutated forms of the …
Isolating The Manganese Superoxide Dismutase Gene (Sod2) From T. Scripta"", Jairo Sanchez
Isolating The Manganese Superoxide Dismutase Gene (Sod2) From T. Scripta"", Jairo Sanchez
Harriet L Wilkes Honors College Theses 2010 - 2019
Reactive oxygen species (ROS) are molecular oxygen-derived molecules that are exceedingly reactive, often generated as free radical bi-products of mitochondrial respiration, which cause oxidative stress that leads to aging. To avoid the generation of ROS, aerobic organisms have antioxidant defense mechanisms that use enzymes such as Superoxide Dismutase (SOD) to convert the superoxide radicals into hydrogen peroxide and oxygen. Manganesecontaining SOD (Mn-SOD), a product of the SOD2 gene is found in all eukaryotic organisms in the mitochondrial matrix, including T. scripta (red-eared slider turtle). Extraordinarily, T. scripta can live without oxygen for long periods of time without experiencing adverse effects …
Fundamental Value And Transaction Frequency: A Cross Sectional Study In Residential Lots, Katherine Towers
Fundamental Value And Transaction Frequency: A Cross Sectional Study In Residential Lots, Katherine Towers
Harriet L Wilkes Honors College Theses 2010 - 2019
The existence of market bubbles raises questions about economists‘ long held assumptions of rationality, costless arbitrage, and the efficient market hypothesis. I take a theoretical approach to the debate on market efficiency by modeling a ―no-value asset,‖ which are residential vacant lots that cannot be developed. I employ a data set that naturally controls for a number of market characteristics thought to contribute to inefficiency. I find that no-value assets traded persistently during the market upturn, in the early 2000s, suggesting limits to arbitrage. In the absence of inefficiency-causing market characteristics, the behavior of agents is likely the cause. To …
Lysander Spooner, Lifestyle Anarchism, And Jury Nullification, Ed Skrod
Lysander Spooner, Lifestyle Anarchism, And Jury Nullification, Ed Skrod
Harriet L Wilkes Honors College Theses 2010 - 2019
Individual anarchism, a social movement of the early nineteenth century, was founded on the principles of self-sovereignty and individualism. One such anarchist, Lysander Spooner, argues in “Vices are not Crimes” that vices should not be criminalized by the State. To do so, “deprive*s+ every man of his… liberty to pursue his own happiness.”1 I argue that Spooner’s essay lays the foundation for “lifestyle anarchism,” the doctrine that all the affairs of human beings within the domain of their lifestyle choices (provided they do not harm the person or property of another), should be managed by individuals or voluntary associations. One …
Studies Towards Synthesis Of Paraconic Acids, Karenia Soto
Studies Towards Synthesis Of Paraconic Acids, Karenia Soto
Harriet L Wilkes Honors College Theses 2010 - 2019
Paraconic acids are naturally occurring compounds synthesized by bacteria and fungi. They are known for having antitumor and antibiotic properties. By use of a phasevanishing (PV) halolactonization with PTFE (Teflon) as a phase screen, we were able to synthesize precursors to these compounds. The PV-PTFE halolactonization of alkenoic acids with iodine monochloride gave the corresponding iodolactones, while halolactonization with bromine gave the corresponding bromolactone. Halolactonization of 4-pentenoic acid with water as a solvent also gave good results. Future experiments will explore the synthesis of further precursors by means of a photolytic carbonylation of iodolactone and a phenylation-ruthenium tetroxide oxidation sequence.
Synthesis And Reactivity Of Organometallic Complexes Of Iridium And Iron In Aqueous And Basic Media, Michael Webster-Gardiner
Synthesis And Reactivity Of Organometallic Complexes Of Iridium And Iron In Aqueous And Basic Media, Michael Webster-Gardiner
Harriet L Wilkes Honors College Theses 2010 - 2019
The catalytic activation of C-H bonds and the subsequent functionalization of hydrocarbons into heteroatom containing products is an area of fundamental importance in chemistry. Three different iridium pincer complexes for C-H activation were synthesized, IrCl3NNN, IrCl3NNN methyl, IrCl3NNNN (NNN= bis-((benzoimidazol))amine), (NNNmethyl = bis-(benzoimidazol)methyl)amine), and (NNNN = tris-((benzoimidazol))amine). These complexes were analyzed for C-H activation between benzoic acid and KOD/D2O solutions. We found that the C-H activation did not proceed catalytically. Also iron containing derivatives containing similar ligand motifs were synthesized , FeCl3NNNN, FeCl3IPI, FeCl3BPB, FeCl3BPB-OH (IPI = 2,6-diimidizoylpyridine, BPB = 2,6-dibenzoimidizoylpyridine, BPB-OH = 4-hydoxy-2,6,dibenzoimidizoylpyridine) and studied for their reactivity towards …
Three Assassins: Women, Revolution And Violence In Modern World History, Ashleah Zigmond
Three Assassins: Women, Revolution And Violence In Modern World History, Ashleah Zigmond
Harriet L Wilkes Honors College Theses 2010 - 2019
This thesis examines three women who committed the unprecedented crime of attempting to assassinate a key male figure in three separate times and places. It involves the government’s and society’s reaction and implications about the role of gender in the violent deeds transforming society at times of revolutionary upheaval. The women examined are Charlotte Corday from eighteenth century France, Vera Zasulich from nineteenth century Russia, and Shi Jianqiao from twentieth century China. These women shared numerous qualities that, when combined, provided the women with the ability to see themselves as equals in the patriarchal societies in which they lived, allowing …
Specificity Of A Back Muscle Roman Chair Exercise In Healthy And Back Pain Subjects, Christian Larivière, Rubens A. Da Silva, A. Bertrand Arsenault, Sylvie Nadeau, André Plamondon, Roger Vadeboncoeur
Specificity Of A Back Muscle Roman Chair Exercise In Healthy And Back Pain Subjects, Christian Larivière, Rubens A. Da Silva, A. Bertrand Arsenault, Sylvie Nadeau, André Plamondon, Roger Vadeboncoeur
Études primaires
No abstract provided.
Dainty Hands: Perceptions Of Women And Crime In Sherlock Holmes Stories, Hadar Aviram
Dainty Hands: Perceptions Of Women And Crime In Sherlock Holmes Stories, Hadar Aviram
Faculty Scholarship
No abstract provided.
The M Word: From Partial Coverture To Skills-Based Fiduciary Duties In Marriage, Jo Carrillo
The M Word: From Partial Coverture To Skills-Based Fiduciary Duties In Marriage, Jo Carrillo
Faculty Scholarship
No abstract provided.
The Cross-Atlantic Law And Economics Divide: A Dissent, Ben Depoorter, Jef De Mot
The Cross-Atlantic Law And Economics Divide: A Dissent, Ben Depoorter, Jef De Mot
Faculty Scholarship
No abstract provided.
The Problem With Health Measurement., Stefan J. Cano, Jeremy C. Hobart
The Problem With Health Measurement., Stefan J. Cano, Jeremy C. Hobart
Peninsula Medical School
In this review we discuss health measurement with a focus on psychometric methods and methodology. In particular, we examine some of the key issues currently facing the use of clinician and patient rating scales to measure the health outcomes of disease and treatment. We present three key facts and flag one crucial problem. First, the numbers generated by scales are increasingly used as the measurements of the central dependent variables upon which clinical decisions are frequently made. The rising profile of rating scales has significant implications for scale construction, evaluation, and selection, as well as for interpreting studies. Second, rating …
Specialization In Plant-Hummingbird Networks Is Associated With Species Richness, Contemporary Precipitation And Quaternary Climate-Change Velocity, B Dalsgaard, E Magard, J Fjeldsa, Amm Gonzalez, C Rahbek, Jm Olesen, J Ollerton, R Alarcon, Ac Araujo, Pa Cotton, C Lara, Cg Machado, I Sazima, M Sazima, A Timmermann, S Watts, B Sandel, Wj Sutherland, J-C Svenning
Specialization In Plant-Hummingbird Networks Is Associated With Species Richness, Contemporary Precipitation And Quaternary Climate-Change Velocity, B Dalsgaard, E Magard, J Fjeldsa, Amm Gonzalez, C Rahbek, Jm Olesen, J Ollerton, R Alarcon, Ac Araujo, Pa Cotton, C Lara, Cg Machado, I Sazima, M Sazima, A Timmermann, S Watts, B Sandel, Wj Sutherland, J-C Svenning
School of Biological and Marine Sciences
No abstract provided.
Fresh Waters And Fish Diversity: Distribution, Protection And Disturbance In Tropical Australia., Stephanie R. Januchowski-Hartley, Richard G. Pearson, Robert Puschendorf, Thomas Rayner
Fresh Waters And Fish Diversity: Distribution, Protection And Disturbance In Tropical Australia., Stephanie R. Januchowski-Hartley, Richard G. Pearson, Robert Puschendorf, Thomas Rayner
School of Biological and Marine Sciences
BACKGROUND: Given the globally poor protection of fresh waters for their intrinsic ecological values, assessments are needed to determine how well fresh waters and supported fish species are incidentally protected within existing terrestrial protected-area networks, and to identify their vulnerability to human-induced disturbances. To date, gaps in data have severely constrained any attempt to explore the representation of fresh waters in tropical regions. METHODOLOGY AND RESULTS: We determined the distribution of fresh waters and fish diversity in the Wet Tropics of Queensland, Australia. We then used distribution data of fresh waters, fish species, human-induced disturbances, and the terrestrial protected-area network …
Biomedical Informatics Seminar Series (Biomiss) 2011 - 2012, Philip Kroth
Biomedical Informatics Seminar Series (Biomiss) 2011 - 2012, Philip Kroth
Biomedical Informatics Seminar Series (BioMISS)
No abstract provided.
Alpha-Level Aggregation: A Practical Approach To Type-1 Owa Operation For Aggregating Uncertain Information With Applications To Breast Cancer Treatments, Shang Ming Zhou, Francisco Chiclana, Robert I. John, Jonathan M. Garibaldi
Alpha-Level Aggregation: A Practical Approach To Type-1 Owa Operation For Aggregating Uncertain Information With Applications To Breast Cancer Treatments, Shang Ming Zhou, Francisco Chiclana, Robert I. John, Jonathan M. Garibaldi
School of Nursing and Midwifery
No abstract provided.
Center For Applied Research In The Apostolate 2010 Annual Survey Of Allegations And Costs, Catholic Church. Archdiocese Of Santa Fe (N.M.)
Center For Applied Research In The Apostolate 2010 Annual Survey Of Allegations And Costs, Catholic Church. Archdiocese Of Santa Fe (N.M.)
Annual Survey of Allegations and Costs
No abstract provided.
Quo Vadis? Public Colleges And Their Funding, Andres C. Salazar
Quo Vadis? Public Colleges And Their Funding, Andres C. Salazar
Electrical & Computer Engineering Faculty Publications
This paper reviews the current debate about the motivation, adequacy and distribution of funding for public colleges. Although the debate has been ongoing for some time, it has become especially heated in recent years due to serious budget problems in many states. In addition, the paper outlines significant trends in higher education which appear to be a reaction to the increasing tuition costs, demographic changes and expectations of employment from a college education. It is expected that the trends in distance education growth, part-time attendance, competition from for-profit colleges, lower subsidy from the state, stagnant population, the lack of college-ready …
Information Surfing For Radiation Building, Chaouki T. Abdallah, R.A. Cortez, H.G. Tanner, R. Lumia
Information Surfing For Radiation Building, Chaouki T. Abdallah, R.A. Cortez, H.G. Tanner, R. Lumia
Electrical & Computer Engineering Faculty Publications
We develop a control scheme for a group of mobile sensors to map radiation over a given planar polygonal region. The advantage of this methodology is that it provides quick situational awareness regarding radiation levels, which is being updated and refined in real- time as more measurements become available. The control algorithm is based on the concept of information surfing, where navigation is done by following information gradients, taking into account sensing performance and the dynamics of the observed process
Unm Health Sciences Center Data Book 2010-11, University Of New Mexico - Health Sciences Center
Unm Health Sciences Center Data Book 2010-11, University Of New Mexico - Health Sciences Center
Health Sciences Center Databook (1990-ongoing)
No abstract provided.
Hslic Annual Report Fy2010-11, Health Sciences Library And Informatics Center
Hslic Annual Report Fy2010-11, Health Sciences Library And Informatics Center
HSLIC Annual Reports
No abstract provided.
2010-2011 Annual Report, Graduate And Professional Student Association
2010-2011 Annual Report, Graduate And Professional Student Association
GPSA Documents
The GPSA has been the recognized Graduate and Professional Student Government at the University of New Mexico since 1969. We strive to represent students on issues ranging from research grants to health insurance to academic freedom. GPSA stays involved on campus by sending representatives to numerous university boards, university and faculty senate committees, and the UNM Board of Regents. GPSA actively lobbies the New Mexico State Legislature for graduate and professional student interests. We also try to meet individual student needs, whether by providing access to our computer lab in SUB 1021, or by funding student research or travel through …
Graduate Resource Manual, Graduate And Professional Student Association
Graduate Resource Manual, Graduate And Professional Student Association
GPSA Documents
No abstract provided.
Unm Hslic Organizational Chart 2011, Sally Bowler-Hill
Unm Hslic Organizational Chart 2011, Sally Bowler-Hill
HSLIC Organizational Charts
No abstract provided.
Why I Can't Love The Homemade Semantic Web, Jason Bengtson
Why I Can't Love The Homemade Semantic Web, Jason Bengtson
Publications
Almost all information professionals agree that the web needs to move to a semantic structure. While work is proceeding in this area, movements to get individual web authors to use semantic markup tools have also been on the rise. This author argues that such efforts are ill conceived and he proposes an automated alternative.
Unm Hslic Strategic Plan Fy2011 - Fy2014, Sally Bowler-Hill
Unm Hslic Strategic Plan Fy2011 - Fy2014, Sally Bowler-Hill
HSLIC Strategic Plans
No abstract provided.