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2011

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Yeast As A Model For Studying Aβ Aggregation, Toxicity And Clearance, Prashant R. Bharadwaj Jan 2011

Yeast As A Model For Studying Aβ Aggregation, Toxicity And Clearance, Prashant R. Bharadwaj

Theses: Doctorates and Masters

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder of the central nervous system, characterised by acute memory loss and behavioural symptoms. The AD brain is characterized by the presence of senile amyloid plaques associated with degenerating neurites and inflammatory processes. The major protein component of these amyloid deposits is the amyloid beta (Aβ) protein. The Aβ protein is a 40 or 42 amino acid cleavage product of APP (Amyloid Precursor Protein) which is produced in low levels in the normal ageing brain. Although senile amyloid plaques is the major pathological hallmark of AD brains, accumulating evidence has been presented to …

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Magnetic Micro-Confinement Of Quantum Degenerate Gases, Ahmed M. Abdelrahman Jan 2011

Magnetic Micro-Confinement Of Quantum Degenerate Gases, Ahmed M. Abdelrahman

Theses: Doctorates and Masters

In this dissertation we explore the basic principles of the magnetic micro-confinement of the quantum degenerate gases where the approach of the so-called two-dimensional magnetic lattices has been theoretically and experimentally investigated. In this research a new generation of two-dimensional magnetic lattice has been proposed and considered as a developing phase for the previous approaches. Its advantage relies on introducing a simplified method to create single or multiple micro-traps of magnetic field local minima distributed, at a certain working distance, above the surface of a thin film of permanent magnetic material. The simplicity in creating the magnetic field local minima …

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Taxonomy And Ecology Of The Western Australian Soldier Crab, Mictyris Occidentalis (Crustacea: Decapoda: Brachyura: Mictyridae), Joyleen Florence Unno Jan 2011

Taxonomy And Ecology Of The Western Australian Soldier Crab, Mictyris Occidentalis (Crustacea: Decapoda: Brachyura: Mictyridae), Joyleen Florence Unno

Theses: Doctorates and Masters

The taxonomy and autoecology of the Western Australian soldier crab, Mictyris occidentalis Unno, 2008 is presented including a new species description, a comprehensive ichnology, sampling methods, an extensive habitat description and a decadal population dynamics study. Such a wide ranging, holistic study has not been carried out for any mictyrid specious previously. In detail, a taxonomy component compares M. occidentalis with congeners, clearly establishing it as a separate species from M. longicarpus to which it was previously referred, and the issues affecting taxonomic classification in the Mictyris genus in general are discussed. A species identification key is provided for the …

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Re-Presenting Gender Fluid Identity In A Contemporary Arts Practice, Matthew Jackson Jan 2011

Re-Presenting Gender Fluid Identity In A Contemporary Arts Practice, Matthew Jackson

Theses: Doctorates and Masters

This dissertation addresses the paucity of representation of gender fluid identity within contemporary imagery. An examination of historical and socio-political structures inherent in modern Western society serves as a foundational position for a broader exploration of differently gendered communities globally. The case is made for contemporary art to be encouraged as a tool for the emancipation of subjugated gender fluid identities. Examples of contemporary gender fluid visual art and artists are presented to illustrate the ability of art to enable agency within the broader gender fluid community. Finally, a commentary on my own artwork is presented and discussed in relation …

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Parental And Carer Responses To Angelman Syndrome And Prader-Willi Syndrome, Allyson K. Thomson Jan 2011

Parental And Carer Responses To Angelman Syndrome And Prader-Willi Syndrome, Allyson K. Thomson

Theses: Doctorates and Masters

The research project undertaken as part of this thesis was designed to assess family stress levels and the use of coping strategies among the carers of people with an intellectual disability caused by Angelman syndrome (AS) or Prader-Willi syndrome (PWS). Both syndromes are genomic imprinting disorders that arise from disruptions in genes located within human chromosome 15q11-q13. Although the disease phenotypes are quite distinct, the genetic mechanisms involved are common to both syndromes but involve paternally-derived mutations in PWS as opposed to maternal mutations in AS. Previous investigations in Western Australia (WA) indicated that people with AS and PWS experience …

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The Impact Of Student Created Slowmation On The Teaching And Learning Of Primary Science, Jeffrey Brown Jan 2011

The Impact Of Student Created Slowmation On The Teaching And Learning Of Primary Science, Jeffrey Brown

Theses: Doctorates and Masters

Current research indicates that although innovations in science teaching are having a positive impact on science education in many Australian schools, national and international assessments show that student achievement is not improving (Hackling & Prain, 2008; Thomson, Wernet, Underwood, & Nicholas, 2008). Furthermore, there is little or no increase in the number of students choosing science as a post-compulsory study option or as a career path. There remains a need to further develop innovative teaching methods that promote the development of students‟ scientific literacy, engenders a joy of science learning through student engagement and encourages a desire to pursue further …

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Systemic Problems Related To Multiple Stakeholders In Technology Adoption And Use In Organizations : A Systems Thinking Perspective, Syed A. Raza Jan 2011

Systemic Problems Related To Multiple Stakeholders In Technology Adoption And Use In Organizations : A Systems Thinking Perspective, Syed A. Raza

Theses: Doctorates and Masters

Understanding and creating the conditions under which information systems will be embraced by human organizations (thinking systems) remain high-priority research issues. Despite numerous benefits associated with information technology (IT), implementing an information system (IS) in organizational environment is challenging. The literature reports numerous IS project failures. During IS implementation, several factors impede technology’s widespread adoption and use in organizations. These organizational problems often result from such barriers or ‘systemic problems’. The proposed work is based on the argument that addressing ‘systemic problems’ can reduce barriers to organizational progress. Most of the IS/IT adoption theories (e.g. TAM, UTAUT, TAM2 and TAM3) …

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