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2011

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A Web Of Knowledge: A Conceptual-Modeling Perspective, David W. Embley, Stephen W. Liddle, Cui Tao Jan 2011

A Web Of Knowledge: A Conceptual-Modeling Perspective, David W. Embley, Stephen W. Liddle, Cui Tao

Faculty Publications

The current web is a web of linked pages. Frustrated users search for facts by guessing which keywords or keyword phrases might lead them to pages where they can find facts. Can we make it possible for users to search directly for facts? Equivalently, can we turn the web into a web of facts (instead of a web of pages containing facts)? Ultimately, can the web be a knowledgebase—a web of knowledge—that can provide direct answers to factual questions and also provide the confidence necessary to make those answers believable? We answer these questions by showing how to superimpose a …


Conceptual Modeling Foundations For A Web Of Knowledge, David W. Embley, Stephen W. Liddle, Deryle W. Lonsdale Jan 2011

Conceptual Modeling Foundations For A Web Of Knowledge, David W. Embley, Stephen W. Liddle, Deryle W. Lonsdale

Faculty Publications

The semantic web purports to be a web of knowledge that can answer our questions, help us reason about everyday problems as well as scientific endeavors, and service many of our wants and needs. Researchers and others expound various views about exactly what this means. Here we propose an answer with conceptual modeling as its foundation. We define a web of knowledge as a collection of interconnected knowledge bundles superimposed over a web of documents. Knowledge bundles are conceptual model instances augmented with facilities that provide for both extensional and intensional facts, for linking between knowledge bundles yielding a web …


A New Printed Quasi-Landstorfor Antenna, Masud Al Aziz Jan 2011

A New Printed Quasi-Landstorfor Antenna, Masud Al Aziz

Electrical and Computer Engineering

In this thesis, a new type of printed quasi-Landstorfer antenna is present ed. The proposed antenna utilizes parasitic radiators to realize a higher gain. The antc1ma is measured to have a resonant frequency of 2.45 GHz with a return loss of -43 cll3. The gain of the antenna is measured to be 7.2 dBi and can be increased to 8 dBi with the design of a folded slot. The gain increment is achieved without increasing the overall dimension of the antenna. Both the measured and the stimulated radiation patterns indicate that the antenna has a symmetric radiation pattern in the …


Tension Of Apel: Perceptions Of Higher Education In Further Education Lecturers, Harriet Dismore, Anne Mcdermott, Neil Witt, Robert Stillwell, Sophie Neville, Mark Stone Jan 2011

Tension Of Apel: Perceptions Of Higher Education In Further Education Lecturers, Harriet Dismore, Anne Mcdermott, Neil Witt, Robert Stillwell, Sophie Neville, Mark Stone

Plymouth Institute of Education

No abstract provided.


An Upper Limit For Macromolecular Crowding Effects, Andrew C. Miklos, Congang Li, Courtney D. Sorell, L. Andrew Lyon, Gary J. Pielak Jan 2011

An Upper Limit For Macromolecular Crowding Effects, Andrew C. Miklos, Congang Li, Courtney D. Sorell, L. Andrew Lyon, Gary J. Pielak

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Background: Solutions containing high macromolecule concentrations are predicted to affect a number of protein properties compared to those properties in dilute solution. In cells, these macromolecular crowders have a large range of sizes and can occupy 30% or more of the available volume. We chose to study the stability and ps-ns internal dynamics of a globular protein whose radius is similar to 2 nm when crowded by a synthetic microgel composed of poly(N-isopropylacrylamide-co-acrylic acid) with particle radii of similar to 300 nm.

Results: Our studies revealed no change in protein rotational or ps-ns backbone dynamics and only mild …


Quantifying Agonist Activity At G Protein-Coupled Receptors, Frederick J. Ehlert, Hinako Suga, Michael T. Griffin Jan 2011

Quantifying Agonist Activity At G Protein-Coupled Receptors, Frederick J. Ehlert, Hinako Suga, Michael T. Griffin

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

When an agonist activates a population of G protein-coupled receptors (GPCRs), it elicits a signaling pathway that culminates in the response of the cell or tissue. This process can be analyzed at the level of a single receptor, a population of receptors, or a downstream response. Here we describe how to analyze the downstream response to obtain an estimate of the agonist affinity constant for the active state of single receptors.

Receptors behave as quantal switches that alternate between active and inactive states (Figure 1). The active state interacts with specific G proteins or other signaling partners. In the absence …


Making And Unmaking Of Transnational Environmental Cooperation, Yooil Bae, Dong-Ae Shin, Yong-Wook Lee Jan 2011

Making And Unmaking Of Transnational Environmental Cooperation, Yooil Bae, Dong-Ae Shin, Yong-Wook Lee

Research Collection School of Social Sciences

There has been an ongoing debate about how (or through what mechanisms) global environmental norms have influenced domestic political debates that give rise to green policy choices. In particular, effective international environmental cooperation between transnational and domestic NGOs has been recognized as a key to successful environmental movements. In this regard, the central question guiding research on the politics of environmental norms is, under what condition(s) transnational cooperation among NGOs would be more likely to be sustained so as to achieve its goals. This article proposes that one of the mechanisms missing from the debate is a bottom-up approach through …


Negotiating Federalism, Erin Ryan Jan 2011

Negotiating Federalism, Erin Ryan

Faculty Publications

Bridging the fields of federalism and negotiation theory, Negotiating Federalism analyzes how public actors navigate difficult federalism terrain by negotiating directly with counterparts across state-federal lines. In contrast to the stylized, zero-sum model of federalism that pervades political discourse and judicial doctrine, the Article demonstrates that the boundary between state and federal power is negotiated on scales large and small, and on an ongoing basis. It is also the first to recognize the procedural tools that bilateral federalism bargaining offers to supplement unilateral federalism interpretation in contexts of jurisdictional overlap.

The Article begins by situating its inquiry within the age-old …


Resolving Conflicts By A Random Device, Erik O. Kimbrough, Roman M. Sheremeta, Timothy W. Shields Jan 2011

Resolving Conflicts By A Random Device, Erik O. Kimbrough, Roman M. Sheremeta, Timothy W. Shields

ESI Working Papers

We examine conflict resolution via a random device. We model conflict as a two-agent rent-seeking contest for a fixed prize. Before conflict arises, both agents may agree to allocate the prize by coin flip to avoid the costs of conflict. In equilibrium, risk-neutral agents with relatively symmetric conflict capabilities agree to resolve the conflict by randomization. However, with sufficiently asymmetric capabilities, conflicts are unavoidable because the stronger agent prefers to fight. Laboratory experiments confirm that the availability of the random device partially eliminates conflicts when agents are relatively symmetric; however, the device also reduces conflict between substantially asymmetric agents.


Real Effort, Real Leisure And Real-Time Supervision: Incentives And Peer Pressure In Virtual Organizations, Brice Corgnet, Roberto Hérnan-Gonzalez, Stephen J. Rassenti Jan 2011

Real Effort, Real Leisure And Real-Time Supervision: Incentives And Peer Pressure In Virtual Organizations, Brice Corgnet, Roberto Hérnan-Gonzalez, Stephen J. Rassenti

ESI Working Papers

We propose a novel approach to the analysis of organizations by developing a computerized platform that reproduces relevant features of existing organizations such as real-effort tasks and real-leisure alternative activities (Internet). In this environment, we find strong incentives effects as organizations using individual incentives significantly outperform those relying on team incentives. Combining real-time peer monitoring with team incentives, we report striking evidence of positive peer effects as production increases by 50% and Internet usage decreases by 54% compared with organizations using team incentives alone. Peer monitoring allows virtual organizations using team incentives to perform as well as those using individual …


Don’T Ask Me If You Will Not Listen: The Dilemma Of Participative Decision Making, Brice Corgnet, Roberto Hérnan-Gonzalez Jan 2011

Don’T Ask Me If You Will Not Listen: The Dilemma Of Participative Decision Making, Brice Corgnet, Roberto Hérnan-Gonzalez

ESI Working Papers

We study the effect of participative decision making in an experimental principalagent game, where the principal can consult the agent’s preferred option regarding the task to be undertaken in the final stage of the game. We show that consulting the agent was beneficial to principals as long as they followed the agent’s choice. Ignoring the agent’s choice was detrimental to the principal as it engendered negative emotions and low levels of transfers. Nevertheless, the majority of principals were reluctant to change their mind and adopt the agent’s proposal. Our results suggest that the ability to change one’s own mind is …


The Effect Of Reliability, Content And Timing Of Public Announcements On Asset Trading Behavior, Brice Corgnet, Praveen Kujal, David Porter Jan 2011

The Effect Of Reliability, Content And Timing Of Public Announcements On Asset Trading Behavior, Brice Corgnet, Praveen Kujal, David Porter

ESI Working Papers

Financial markets are overwhelmed by daily announcements. We use experimental asset markets to assess the impact of releasing public messages with different levels of reliability on asset prices. Subjects receive qualitative announcements in predetermined trading periods that are either preset by the experimenter, randomly selected, or determined by past asset market prices. We find that messages can play a significant role in bubble abatement, or rekindling. The preset message, “The price is too high,” decreases the amplitude and duration of bubbles for inexperienced subjects. Announcements that depend on the actual level of mispricing reduce bubble magnitude. Meanwhile, a preset or …


Same-Sex Marriage And The New Judicial Federalism: Why State Courts Should Not Consider Out-Of-State Backlash, Neal Devins Jan 2011

Same-Sex Marriage And The New Judicial Federalism: Why State Courts Should Not Consider Out-Of-State Backlash, Neal Devins

Faculty Publications

No abstract provided.


The State (Never) Rests: How Excessive Prosecutor Caseloads Harm Criminal Defendants, Adam M. Gershowitz, Laura R. Killinger Jan 2011

The State (Never) Rests: How Excessive Prosecutor Caseloads Harm Criminal Defendants, Adam M. Gershowitz, Laura R. Killinger

Faculty Publications

No abstract provided.


Leiter On The Legal Realists, Michael S. Green Jan 2011

Leiter On The Legal Realists, Michael S. Green

Faculty Publications

In this essay reviewing Brian Leiter’s recent book Naturalizing Jurisprudence, I focus on two positions that distinguish Leiter’s reading of the American legal realists from those offered in the past. The first is his claim that the realists thought the law is only locally indeterminate – primarily in cases that are appealed. The second is his claim that they did not offer a prediction theory of law, but were instead committed to a standard positivist theory. Leiter’s reading is vulnerable, because he fails to discuss in detail those passages from the realists that inspired past interpretations. My goal is to …


Radio Spectrum And The Disruptive Clarity Of Ronald Coase, Thomas W. Hazlett, David P. Porter, Vernon L. Smith Jan 2011

Radio Spectrum And The Disruptive Clarity Of Ronald Coase, Thomas W. Hazlett, David P. Porter, Vernon L. Smith

Economics Faculty Articles and Research

In the Federal Communications Commission, Ronald Coase exposed deep foundations via normative argument buttressed by astute historical observation. The government controlled scarce frequencies, issuing sharply limited use rights. Spillovers were said to be otherwise endemic. Coase saw that Government limited conflicts by restricting uses; property owners perform an analogous function via the “price system.” The government solution was inefficient unless the net benefits of the alternative property regime were lower. Coase augured that the price system would outperform. His spectrum auction proposal was mocked by communications policy experts, opposed by industry interests, and ridiculed by policy makers. Hence, it took …


Prenatal Programming Of Human Neurological Function, Curt A. Sandman, Elyssia Poggi Davis, Claudia Buss, Laura M. Glynn Jan 2011

Prenatal Programming Of Human Neurological Function, Curt A. Sandman, Elyssia Poggi Davis, Claudia Buss, Laura M. Glynn

Psychology Faculty Articles and Research

The human placenta expresses the genes for proopiomelanocortin and the major stress hormone, corticotropin-releasing hormone (CRH), profoundly altering the "fight or flight" stress system in mother and fetus. As pregnancy progresses, the levels of these stress hormones, including maternal cortisol, increase dramatically. These endocrine changes are important for fetal maturation, but if the levels are altered (e.g., in response to stress), they influence (program) the fetal nervous system with long-term consequences. The evidence indicates that fetal exposure to elevated levels of stress hormones (i) delays fetal nervous system maturation, (ii) restricts the neuromuscular development and alters the stress response of …


Unconscious Vigilance: Worldview Defense Without Adaptations For Terror, Coalition Or Uncertainty Management, Colin Holbrook, Paulo Sousa, Jennifer Hahn-Holbrook Jan 2011

Unconscious Vigilance: Worldview Defense Without Adaptations For Terror, Coalition Or Uncertainty Management, Colin Holbrook, Paulo Sousa, Jennifer Hahn-Holbrook

Psychology Faculty Articles and Research

Individuals subtly reminded of death, coalitional challenges, or feelings of uncertainty display exaggerated preferences for affirmations and against criticisms of their cultural in-groups. Terror management, coalitional psychology, and uncertainty management theories postulate this “worldview defense” effect as the output of mechanisms evolved either to allay the fear of death, foster social support, or reduce anxiety by increasing adherence to cultural values. In 4 studies, we report evidence for an alternative perspective. We argue that worldview defense owes to unconscious vigilance, a state of accentuated reactivity to affective targets (which need not relate to cultural worldviews) that follows detection of subtle …


Parental Precaution: Neurobiological Means And Adaptive Ends, Jennifer Hahn-Holbrook, Colin Holbrook, Martie G. Haselton Jan 2011

Parental Precaution: Neurobiological Means And Adaptive Ends, Jennifer Hahn-Holbrook, Colin Holbrook, Martie G. Haselton

Psychology Faculty Articles and Research

Humans invest precious reproductive resources in just a few offspring, who remain vulnerable for an extended period of their lifetimes relative to other primates. Therefore, it is likely that humans evolved a rich precautionary psychology that assists in the formidable task of protecting offspring. In this review, we integrate precautionary behaviors during pregnancy and postpartum with the adaptive functions they may serve and what is known of their biological mediators, particularly brain systems motivating security and attachment. We highlight the role of reproductive hormones in (i) priming parental affiliation with young to incentivize offspring protection, (ii) focusing parental attention on …


Enabling Refugee And Idp Law And Policy: Implications Of The U.N. Convention On The Rights Of Persons With Disabilities, Professor Michael Stein, Janet E. Lord Jan 2011

Enabling Refugee And Idp Law And Policy: Implications Of The U.N. Convention On The Rights Of Persons With Disabilities, Professor Michael Stein, Janet E. Lord

Articles

No abstract provided.


A Presidency Upstaged: The Public Leadership Of George Bush, Joseph V. Hughes Jr. And Holly O. Hughes, Lori Cox Han Jan 2011

A Presidency Upstaged: The Public Leadership Of George Bush, Joseph V. Hughes Jr. And Holly O. Hughes, Lori Cox Han

Political Science Faculty Books and Book Chapters

A president who distances himself from stagecraft will find himself upstaged. George H. W. Bush sought to “stay the course” in terms of policy while distancing himself from the public relations strategies employed during the administration of Ronald Reagan, his predecessor. But Bush discovered during his one-term presidency that a strategy of policy continuity coupled with mediocre communication skills “does not make for a strong public image as an effective and active leader in the White House", as author and scholar Lori Cox Han demonstrates in A Presidency Upstaged.

Incorporating extensive archival research from the George Bush Presidential Library at …


The Energy Landscape Analysis Of Cancer Mutations In Protein Kinases, Anshuman Dixit, Gennady M. Verkhivker Jan 2011

The Energy Landscape Analysis Of Cancer Mutations In Protein Kinases, Anshuman Dixit, Gennady M. Verkhivker

Mathematics, Physics, and Computer Science Faculty Articles and Research

The growing interest in quantifying the molecular basis of protein kinase activation and allosteric regulation by cancer mutations has fueled computational studies of allosteric signaling in protein kinases. In the present study, we combined computer simulations and the energy landscape analysis of protein kinases to characterize the interplay between oncogenic mutations and locally frustrated sites as important catalysts of allostetric kinase activation. While structurally rigid kinase core constitutes a minimally frustrated hub of the catalytic domain, locally frustrated residue clusters, whose interaction networks are not energetically optimized, are prone to dynamic modulation and could enable allosteric conformational transitions. The results …


Quaternionic Hermitian Spinor Systems And Compatibility Conditions, Alberto Damiano, David Eelbode, Irene Sabadini Jan 2011

Quaternionic Hermitian Spinor Systems And Compatibility Conditions, Alberto Damiano, David Eelbode, Irene Sabadini

Mathematics, Physics, and Computer Science Faculty Articles and Research

In this paper we show that the systems introduced in [12] and [22] are equivalent, both giving the notion of quaternionic Hermitian monogenic functions. This makes it possible to prove that the free resolution associated to the system is linear in any dimension, and that the first cohomology module is nontrivial, thus generalizing the results in [22]. Furthermore, exploiting the decomposition of the spinor space into sp(m)-irreducibles, we find a certain number of "algebraic" compatibility conditions for the system, suggesting that the usual spinor reduction is not applicable.


Whiskey, Soldiers, And Voting: Western Virginia Elections In The 1790s, Jud Campbell Jan 2011

Whiskey, Soldiers, And Voting: Western Virginia Elections In The 1790s, Jud Campbell

Law Faculty Publications

Editor's Note: Elections in eighteenth-century Virginia were conducted quite differently than current elections. In this article, the author presents revealing descriptions of early elections in Montgomery County, Virginia immediately following the birth of the United States. The behavior and motivations of the electorate, as well as the candidates, provide interesting insight regarding the social structure o/that era.


Reviewing Joan Delfattore's Knowledge In The Making, Suzanne B. Corriell Jan 2011

Reviewing Joan Delfattore's Knowledge In The Making, Suzanne B. Corriell

Law Faculty Publications

A book review of Joan DelFattore's Knowledge in the Making.


Reviewing Holy Writ: Interpretation In Law And Religion, Henry L. Chambers Jr. Jan 2011

Reviewing Holy Writ: Interpretation In Law And Religion, Henry L. Chambers Jr.

Law Faculty Publications

Holy Writ: Interpretation in Law and Religion is precisely what its title suggests. The book consists of “assembled essays on interpretation in the field of law and religion” written by Justice Antonin Scalia and professors of law and philosophy from the University of Leiden and the University of Utrecht. The genesis of the book was “a conference in the honour of Justice Antonin Scalia, who visited the Leiden law department to celebrate the opening of the new faculty building.” (Preface, ix) The structure of the book makes it particularly enjoyable. The collection is aptly likened to a chain novel in …


Judge Thompson And The Appellate Court Confirmation Process, Carl W. Tobias Jan 2011

Judge Thompson And The Appellate Court Confirmation Process, Carl W. Tobias

Law Faculty Publications

Judge 0. Rogeriee Thompson's appointment to the United States Court of Appeals for the First Circuit was an historic moment, as she became the tribunal's first African American member. The Senate confirmed her in five months on a 98-0 vote, more expeditiously than any of President Barack Obama's other appellate nominees. Indeed, Fourth Circuit nominee Judge Albert Diaz waited thirteen months for approval. The slow pace of judicial confirmation demonstrates that the charges and recriminations, the partisanship and the serial paybacks, which have infused appointments for two decades, remain. Judge Thompson's confirmation, accordingly, deserves celebration and recounting. It both illuminates …


Virginia Should Abolish The Archaic Tort Defense Of Contributory Negligence And Adopt A Comparative Negligence Defense In Its Place, Peter N. Swisher Jan 2011

Virginia Should Abolish The Archaic Tort Defense Of Contributory Negligence And Adopt A Comparative Negligence Defense In Its Place, Peter N. Swisher

Law Faculty Publications

The purpose of this essay is to argue that the time has now come for Virginia, by judicial or legislative action, to abolish its archaic common law tort defense of contributory negligence and replace it with a comparative negligence defense. Adopting a comparative negligence defense would more equitably and more fairly recognize and apportion damages according to the bedrock underlying tort legal principles of accountability, deterrence, and distribution of loss.


Women And Peace Talks In Africa, Akin Iwilade Jan 2011

Women And Peace Talks In Africa, Akin Iwilade

Journal of International Women's Studies

This paper interrogates the role of women in peace talks in Africa. It addresses the exclusion of women and their peculiar interests from deliberations aimed at constructing a post conflict state framework that resolves the contradictions that incite violent conflict and provides safeguards against recurrence. The paper argues that the failure of peace talks to deliberately incorporate women interests detracts from their potential to effectively confront the questions of post conflict rebuilding. It notes the increasing inclusion of women but argues that this does not amount to gender representation. This is because at the heart of the inclusion is the …


Women Under Attack: Violence And Poverty In Guatemala, Corinne Ogrodnik, Silvia Borzutzky Jan 2011

Women Under Attack: Violence And Poverty In Guatemala, Corinne Ogrodnik, Silvia Borzutzky

Journal of International Women's Studies

In 2009 Guatemalan women experienced the highest level of violence in Latin America and one of the highest in the world, and death rates have continued to increase in 2010. At the core of the issue are two major problems: pervasive poverty and legal exclusion. In turn, these two issues are closely connected since legal/judicial exclusion is a consequence of poverty. This paper aims to analyze the question of violence against women in Guatemala, to discuss women’s limited political, legal and economic rights, as well as the policies pursued since the end of Guatemala’s civil war to deal with the …