Digital Commons Network^™

Neuroanatomic Predictors To Prodromal Psychosis In Velocardiofacial Syndrome (22q11.2 Deletion Syndrome): A Longitudinal Study, Wendy R. Kates, Kevin M. Antshel, Stephen V. Faraone, Wanda Fremont, Anne Marie Higgins, Robert J. Shprintzen, Jo-Anna Botti, Lauren Kelchner, Christopher Mccarthy

Communication Disorders Faculty Publications

Background: Up to 30% of young adults with velocardiofacial syndrome (VCFS; 22q11.2 deletion syndrome) develop schizophrenia or psychosis. Identifying the neuroanatomic trajectories that increase risk for psychosis in youth with this genetic disorder is of great interest. Methods: We acquired high-resolution anatomic MR images and measures of psychiatric function on 72 youth with VCFS, 26 unaffected siblings and 24 age-matched community controls at two timepoints, between late childhood (mean age, 11.9 years) and mid-adolescence (mean age, 15.1 years). Results: With the exception of cranial gray matter and orbitofrontal prefrontal cortex, neuroanatomic trajectories in youth with VCFS were comparable to unaffected …

Control System For Mass Spectrometer, Jian Xu

Purdue Polytechnic Masters Theses

Mass spectrometry (MS) is a very popular analytical methodology that measures the mass of ions using a mass spectrometer. It is widely used for determining masses of chemicals, the elemental composition of a sample and molecule structure. The process of mass spectrometry normally consists of ionizing chemical compounds to ions and measuring their ratios of mass to charge for analysis.

MS instruments consist of three modules: Ionization, Analysis and detection. A LabVIEW system was developed to control the three modules of a mass spectrometer, giving the required signals in a right sequence. Experiments can be carried out by using the …

To Be Or Not To Be Exposed To Direct Sunlight : Vitamin D Deficiency In Oman, Moeness M. Alshishtawy

Sultan Qaboos University Medical Journal

Only small amounts of vitamin D come from dietary sources as it is mainly synthesised in the skin from the ultraviolet B (UVB) fraction of sunlight if the person is sufficiently exposed to direct sunlight. Vitamin D deficiency has been well documented in Oman. The "2004 Oman National Micronutrients Survey" and other recent studies revealed that vitamin D3 stores are low among healthy Omani females of childbearing age and pregnant women. This situation is confusing as Oman is known to be one of the sunniest countries in the world. However, it is known that most Omani women are well covered …

Dengue Haemorrhagic Fever Presenting As Acute Abdomen, Hanaa Al-Araimi, Amal Al-Jabri, Arshad Al-Abri, Seif

Sultan Qaboos University Medical Journal

We describe a case of a 38 year-old Sri Lankan female who was referred to the surgeon on call with a picture of acute abdomen. She presented with a three-day history of fever, headache, abdominal pain and diarrhoea; however, the physical examination was not consistent with acute abdomen. Her platelet count was 22 x109/L. A diagnosis of dengue haemorrhagic fever (DHF) was made and dengue serology was positive. Dengue epidemics have been associated with a variety of gastrointestinal symptoms and signs, including acute abdomen. Acute abdomen in patients with DHF makes the diagnosis and management challenging.

Effects Of Hydrogen Sulphide On The Isolated Perfused Rat Heart, Afthab Hussain, Helen Maddock, Hajar Carson, Ray J.

Sultan Qaboos University Medical Journal

Objectives: Hydrogen sulphide has been identified as a gas signalling molecule in the body, and has previously been shown to have vasorelaxant properties. The aim of the study was to investigate the effects of sodium hydrosulphide (NaHS), a hydrogen sulphide donor, on heart rate (HR), left ventricular developed pressure (LVDP) and coronary flow (CF) in the isolated perfused rat heart. Methods: A Langendorff isolated heart preparation was used to investigate the effect of a dose range of sodium hydrosulphide, in the presence and absence of inhibitors, on heart rate, left ventricular developed pressure and coronary flow. Results: Sodium hydrosulphide caused …

The Role Of Pharmacokinetics And Pharmacodynamics In Early Drug Development With Reference To The Cyclin-Dependent Kinase (Cdk) Inhibitor - Roscovitine, Moustapha Hassan, Hatem Sallam, Zuzana

Sultan Qaboos University Medical Journal

Pharmacokinetics, pharmacodynamics and pharmacogenetics play an important role in drug discovery and contribute to treatment success. This is an essential issue in cancer treatment due to its high toxicity. During the last decade, cyclin-dependent kinase inhibitors were recognised as a new class of compounds that was introduced for the treatment of several diseases including cancer. Cyclin-dependent kinases (Cdks) play a key role in the regulation of cell cycle progression and ribonucleic acid transcription. Deregulation of Cdks has been associated with several malignancies, neurodegenerative disorders, viral and protozoa infections, glomerulonephritis and inflammatory diseases. (R)-roscovitine is a synthetic tri-substituted purine that inhibits …

Mmp-13 Selective Alpha-Sulfone Hydroxamates: Identification Of Selective P1' Amides, Yvette M. Fobian, John N. Freskos, Thomas E. Barta, Louis J. Bedell, Daniel Becker

Chemistry: Faculty Publications and Other Works

Continuing our interest in designing compounds preferentially potent and selective for MMP-13, we report on a series of hydroxamic acids with a flexible amide P1' substituents. We identify an amide which spares both MMP-1 and -14, and shows >500 fold selectivity for MMP-13 versus MMP-2 and -8.

Oman International Conference On Laboratory Medicine – Part Ii Sultan Qaboos University 9 – 11th November 2010, Sultan Qaboos University

Sultan Qaboos University Medical Journal

No abstract provided.

Complementary And Alternative Medicine : Where Do We Stand In The 21st Century?, Lamk Al-Lamki

Sultan Qaboos University Medical Journal

No abstract provided.

Sent To Explore, Conquer And Heal History Of The Evolution Of Biomedicine In Oman During The 19th Century, Nasser H. Al-Azri

Sultan Qaboos University Medical Journal

During the past four decades, Oman has transformed into a modern state with remarkable changes in all fields, including public health and the provision of medical services. Little attention has been paid so far to the history of the development of biomedicine in Oman. A history of healing practices, just like clinical patient histories, helps to diagnose problems, plan interventions and predict their future within a dynamic context. This study is the first to explore the beginnings and evolution of biomedicine in Oman during the 19th century, categorising it into three eras: from the casual system offered by occasional visiting …

Advanced General Medicine Conference Joint Conference Of Sultan Qaboos University And The Ministry Of Health, Oman 23rd–24th February 2011, Sultan Qaboos University

Sultan Qaboos University Medical Journal

No abstract provided.

In Search Of Parity: Child Custody/Visitation And Child Support For Lesbian Couples Under “Companion” Cases Debra H. And In Re H.M., Jason C. Beekman

Cornell Law School J.D. Student Research Papers

The United States is engaged in a national debate over whether to grant same-sex couples the rights and privileges of marriage.  Supporters of marriage equality flood the media with images of jubilant same-sex couples simply wanting the chance to say their “I dos” and have the state formally recognize their shared love and commitment. The unfortunate reality is, however, that many homosexual relationships, like heterosexual relationships, dissolve. Marriage rights play as important a role at a relationship’s dissolution as they do at a relationship’s inception. This paper focuses on one such issue often left out of the public discourse over …

2011 Spring Boise State University Commencement Program, Boise State University Commencement Committee

Commencement Programs

No abstract provided.

Written In Stone, Michelle Day

Mahurin Honors College Capstone Experience/Thesis Projects

John Peter Zenger, Elijah Lovejoy, Gordon Parks, Walter Winchell and Katherine Graham were five famous journalists who impacted the industry in enduring ways. Whether writers, publishers or a photographer, these storytellers have had their stories told countless times over many years. This project seeks to combine journalistic research with a personal experiment in creative writing. Each chapter consists of story about one of the journalists, told either from their own perspective or someone else’s. Each piece should be considered historical fiction — not nonfiction — but the overall message and basic facts are true. Each story is different but reflects …

2011 Commencement Program, Longwood University

Undergraduate Commencement Programs

Itinerary and list of graduates for 2011 commencement.

Spring Commencement: May 14, 2011, University Of North Dakota

UND Commencement Programs

UND Spring Commencement program from May 14, 2011.

Characterization Of Esterase Activity From The Bacteria, Francisella Tularensis, The Causative Agent Of Tularemia, Leigh Anna Weston

Undergraduate Honors Thesis Collection

Francisella tularensis is the bacteria responsible for causing the disease tularemia and is listed as one of the top three-biowarfare agents. Among the proteins essential to the virulence and infectivity of F.tularensis are multiple esterases, which are enzymes that break down various ester, thioester, and amide bonds. In this project, the catalytic activity, substrate speci fi city, and structure of a putative esterase from F.tularensis was studied. Latent fluorophores based on the molecule, fluorescein, were unmasked by the enzymatic activity of the esterase and the increase in fluorescence was measured over time to determine how well the e tcrase recognized …

What Do You Expect? : An Investigation Of How Caffeine Expectancies Affect College Students' Cognitive Performances, Katie Alyse Berg

Undergraduate Honors Thesis Collection

Caffeine use is common, but few studies have examined how the expectancies that people hold about caffeine relate to the effects they experience after consuming it. My study examined how typical caffeine consumption and students' expectancies about how caffeine generally affects them influence their decisions about caffeine use as well as their performance on memory and attention tests. I hypothesized that expectations about how caffeine affects students would interact with their beliefs about how much caffeine they had consumed to impact performance on tests of attention and memory. Undergraduate students were divided into four groups: high consumption and high expectancy, …

Cultural Definitions Of Health Care: A Case Study Of Burmese Refugees, Marielena Rose White

Undergraduate Honors Thesis Collection

As a result of ongoing civil war and civil unrest in the Southeast Asian country of Myanmar, every year the United States accepts increasing numbers of refugees from Burma of which there is a population of significance within the greater Indianapolis area. When considering options for health care, Burmese refugees may opt for self care as opposed to care from a health care professional as a result of clashing cultural factors or fears of the unknown.

This study aims to uncover how members of the Chin ethnic group have been challenged or confronted by the social, cultural, and political institutions …

University Of Mississippi Commencement, 2011, University Of Mississippi, Daniel W. Jones, Morris H. Stocks, Freeman A. Hrabowski Iii

Commencement Programs

No abstract provided.

Chiral Recognition Study Of A Bimolecular Process In Amino Acid Chiral Ionic Liquids, Laurel Millikan Heckman

Undergraduate Honors Thesis Collection

In this study, chiral ionic liquid (CIL) solvents were prepared and tested for their chiral discrimination ability by probing with luminescence quenching. The CIL's were also tested for their impurities, viscosity and density. These experiments will help to determine the ability of CIL's to act as solvents in asymmetric catalysis. The chiral ionic liquids in this study were composed of amino acid methyl ester cations and bis(trifluoromethane) sulfonimide or bistri flimide anions (i.e. I-alanine methyl ester bistriflimid e, d-alanine methyl ester bistr iflim ide and I-leuci ne methyl ester bistriflimde). Circularly polarized luminescence (CPL) and its quenching in the chiral …

Effects Of Exposure To Low, Ecologically Relevant Doses Of Atrazine On Somatic And Gonadal Development In American Toad (Bufo Americanus) Tadpoles, Tyler Davis Hoskins

Undergraduate Honors Thesis Collection

Atrazine is the most commonly used herbicide in the United States, with 80 million pounds applied annually, making it the most common contaminant of ground and surface water nationwide. It has been shown to act as a potent endocrine disrupter in amphibians, causing altered somatic and gonadal development in the ecologically relevant part per billion range; as a result, it has been hypothesized that atrazine may be a major factor behind amphibian declines. However, responses of different species to the chemical vary widely, and have made predicting susceptibility difficult. Recently, it has been shown that life history can serve as …

How Sweet Is It, Really? The Anomalous Effects Of Glucose At Retrieval, Sarah A. Gillott

Undergraduate Honors Thesis Collection

151 participants gave free recall and probed response memories for best kisses and The Lion King. Blood-glucose levels were manipulated at retrieval with glucose (50g) or saccharin (35mg) in the form of a lemonade drink. Memories for best kisses were more elaborate than memories for The Lion King. This may be due to the fact that best kiss memories were rated as more arousing than film memories. Regardless, high blood-glucose levels as a result of glucose consumption significantly impaired autobiographical kiss memory, yet enhanced semantic memory for The …

Development Of A Green Method For Amide Synthesis, Megan Ruth Darragh

Undergraduate Honors Thesis Collection

The aim of this work was to determine the scope and limitations of using microwave technology, solvent-free conditions and green chemistry-applicable solid supports for amide synthesis. We hypothesize that the method developed by Comerford et al [12] may be applicable to other solid support systems already in use (silica, fly ash, and alumina), and that combined with the use of microwave technology, green and efficient synthesis of varied amides and other dehydration reaction products may be possible. These methods should show application to undergraduate, organic chemistry laboratories as well as large-scale production laboratories.

2011 Spring Commencement, Harding University

Commencement Programs

Program for the Commencement on May 14.

Commencement Speaker: Tim Griffin

2011-05-14 Minutes & Appendices, Longwood University

Board of Visitors Meeting Minutes 1964-

No abstract provided.

Equitent Problems, Payton E. Lindsay, Katelynn Kochalski, Gary R. Lawlor Phd

Honors Theses

No abstract provided.

University Of Montana Commencement Program, 2011, University Of Montana--Missoula. Office Of The Registrar

University of Montana Commencement Programs, 1898-2020

Commencement program from the University of Montana.

2011 Ursinus College Commencement Program, Ursinus College

Ursinus College Commencement Programs

This Ursinus College Commencement program from 2011 contains the list of speakers and order of events for the day.

2011 Lynn University Commencement Program - Undergraduate Day Students, Lynn University

Commencement Programs

The commencement program for Lynn University's 2011 Undergraduate Day Students, held on Saturday, May 14, 2011 in the Count and Countess de Hoernle Sports and Cultural Center.

The commencement speaker was Jeb Bush, Former Florida Governor.