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Studying Milk Coagulation Kinetics With Laser Scanning Confocal Microscopy, Image Processing, And Computational Modeling, Richard Joseph Hennessy

Master's Theses

The kinetics of milk coagulation are complex and still not well understood. A deeper understanding of coagulation and the impact of the relevant factors would aid in both cheese manufacturing and also in determining the nutritional benefits of dairy products. A method using confocal microscopy was developed to follow the movement of milk fat globules and the formation of a milk protein network during the enzyme-induced coagulation of milk. Image processing methods were then used to quantify the rate of coagulation. It was found that the texture of the protein network is an indicator of the current status of the …

Characterization And Implementation Of A Decellularized Porcine Vessel As A Biologic Scaffold For A Blood Vessel Mimic, Aubrey N. Smith

Master's Theses

Every 34 seconds, someone in the United States suffers from a heart attack.  Most heart attacks are caused by atherosclerotic build up in the coronary arteries, occluding normal blood flow.  Balloon angioplasty procedures in combination with a metal stent often result in successful restoration of normal blood flow.  However, bare metal stents often lead to restenosis and other complications.  To compensate for this problem, industry has created drug-eluting stents to promote healing of the artery wall post stenting.  These stents are continually advancing toward better drug-eluting designs and methods, resulting in a need for fast and reliable pre-clinical testing modalities. …

Implementation And Assessment Of Hyperglycemic Conditions For The Creation Of A Diabetic Blood Vessel Mimic, Vikramaditya Mediratta

Master's Theses

Introduction: Diabetes Mellitus is a metabolic disorder that affects a person’s ability to either produce insulin (Type I diabetes mellitus) or properly use insulin (Type II diabetes mellitus) in order to maintain adequate blood glucose levels. The most severe diabetic complications arise due to hyperglycemia – a state of extremely high blood glucose levels – such as, coronary artery disease (CAD), in which coronary stent therapy is a popular method of treatment. However, research has shown a high rate of in-stent restenosis in diabetic patients with CAD, most likely due to activation of cellular adhesion molecules on endothelial cells exposed …

The Ma-10 Cell Line As A Model Of Insl3 Regulation And Leydig Cell Function, Mary E. Strong

Master's Theses

Leydig cells produce testosterone in response to luteinizing hormone (LH) via the cyclic adenosine monophosphate (cAMP)/protein kinase A pathway. Additionally, these cells are responsible for producing insulin-like peptide 3 (INSL3), a peptide hormone that is essential for testicular descent. The insl3 promoter in Leydig cells can be activated by cAMP through the transcription factor Nur77, which has also been shown to regulate the promoters of the steroidogenic enzymes, cyp17 and 3b-hsd. While the mechanism of LH action on testosterone production is well characterized, the effect of LH on insl3 abundance has yet to be shown directly. The MA-10 …

A Comparative Study Of Methods To Explore Searchers' Affective Perceptions Of Images, Jungwon Yoon

School of Information Faculty Publications

Introduction. Previous search query analysis studies demonstrated that emotional perceptions and needs tend not to be sufficiently reflected in image queries. To provide a better understanding of the emotional attributes of an image, this study explored and compared such attributes obtained from related tasks.

Method. This study analysed attributes of an image through sorting, describing and searching. A data-set was obtained from Flickr images tagged with one of six basic emotions (love, joy, surprise, anger, sadness and fear); fifty-nine students participated.

Results. The sorting and describing tasks revealed two categories of emotions, joy and sadness, which people perceive from …

Emmett Oliver's Story: Psycho-Social Development Of An Extraordinary Native American, Susanna A. Hayes

Online Readings in Psychology and Culture

Emmett Oliver's life story offers clear evidence that human resilience originates in a combination of many aspects of personality traits, abilities and interests, and supportive social relationships. Living in an era when many of his Native peers did not develop their talents or find a meaningful place in their rapidly changing cultures, Emmett pursued an education. He became a teacher, a Coast Guard Commander, a counselor, and an educational policy maker. His achievements severed to bolster his motivation when he felt drawn to a less challenging work.

Creativity In The Brazilian Culture, Denise S. Fleith

Online Readings in Psychology and Culture

Research has pointed out creativity as a sociocultural and contextually embedded phenomenon. As a consequence, the effect of cultural factors on the manifestation of creativity has been discussed worldwide. The purpose of this chapter is, therefore, to analyze the development of creativity in the Brazilian culture. A brief description of the Brazilian culture is provided. Models of creativity developed by Brazilian researchers, as well as a review of creativity studies conducted in the educational environment, are presented. Guidelines for future cross-cultural studies on creativity are also suggested.

Structure Of The Atp Synthase Catalytic Complex (F(1)) From Escherichia Coli In An Autoinhibited Conformation., Gino Cingolani, Thomas M Duncan

Department of Biochemistry and Molecular Biology Faculty Papers

ATP synthase is a membrane-bound rotary motor enzyme that is critical for cellular energy metabolism in all kingdoms of life. Despite conservation of its basic structure and function, autoinhibition by one of its rotary stalk subunits occurs in bacteria and chloroplasts but not in mitochondria. The crystal structure of the ATP synthase catalytic complex (F(1)) from Escherichia coli described here reveals the structural basis for this inhibition. The C-terminal domain of subunit ɛ adopts a heretofore unknown, highly extended conformation that inserts deeply into the central cavity of the enzyme and engages both rotor and stator subunits in extensive contacts …

2011/2012 University Of The Pacific General Catalog, University Of The Pacific

Catalogue, Bulletin, Catalog

No abstract provided.

Seawater/Wastewater Production Of Microalgae-Based Biofuels In Closed Loop Tubular Photobioreactors, Joshua Bradley Lowrey

Master's Theses

The push for alternatives to petroleum fuels has forced researchers to look for highly productive, renewable, non-food resources.  The advantages of using microalgae instead of traditional oil crops for biofuel production include high oil yields, rapid reproductive rates, and versatile growing requirements.  In order to reduce the cost of producing microalgae based biofuels, wastewater has been used as a nutrient source instead of specialized plant nutrients.  The purpose of this study was to compare the relative effectiveness of different combinations of microalgae strain and dairy wastewater for increasing biomass.  The methods for monitoring growth included optical density, cell counting, biomass …

Endothelial Differentiation Of Adipose-Derived Stem Cells From Elderly Patients With Cardiovascular Disease., Ping Zhang, Neil Moudgill, Eric Hager, Nicolas Tarola, Christopher Dimatteo, Stephen Mcilhenny, Thomas Tulenko, Paul J Dimuzio

Department of Surgery Faculty Papers

Adipose-derived stem cells (ASCs) possess significant therapeutic potential for tissue engineering and regeneration. This study investigates the endothelial differentiation and functional capacity of ASCs isolated from elderly patients. Isolation of ASCs from 53 patients (50-89 years) revealed that advanced age or comorbidity did not negatively impact stem cell harvest; rather, higher numbers were observed in older donors (>70 years) than in younger. ASCs cultured in endothelial growth medium-2 for up to 3 weeks formed cords upon Matrigel and demonstrated acetylated-low-density lipoprotein and lectin uptake. Further stimulation with vascular endothelial growth factor and shear stress upregulated endothelial cell-specific markers (CD31, …

Development Of An In-Vitro Hyperglycemic Tissue Engineered Blood Vessel Mimic, Brian C. Wong

Biomedical Engineering

No abstract provided.

Things Are In People, People Are In Things: A Phenomenological Approach To H.D.'S Hermione And The Modernist Prosthetic Body, Alison Stone Roberg

Theses and Dissertations

H.D.'s autobiographical novel HERmione is phenomenological in texture. It portrays both sides of a dynamic process: the individual "creates" the world by adjusting a "psychic lens," projecting a mental space in which objects can appear; yet at the same time, the world imposes itself on the sensing subject. The framework within which this dynamic process occurs is the body; as the novel portrays, the body is the site of juxtapositions and transformations as it comes into contact with the world. In this article, I discuss the ways in which H.D. explores the boundaries and intersections between the human body and …

Heat Shock Proteins As Novel Cancer Therapeutics: Targeting The Hallmarks Of Cancer, Chao Li

Theses and Dissertations

Molecular chaperones, commonly known as heat shock proteins (HSPs), are essential for mammalian cells to maintain homeostasis, and HSPs function by inducing an ATPase-coupled structural change, followed by interactions with diverse co-chaperones and over 200 client proteins implicated in many critical signaling networks. These highly expressed HSPs participate in the onset and progression of several human diseases including cancer, and their connection with tumorigenesis has facilitated research and clinical trials related to targeting HSPs as a novel anti-tumor therapy. The predominant mechanism of chaperone inhibition is through either disruption of the HSP association with client protein or an altered binding …

Model Predictive Control Of Blood Pressure By Drug Infusion, Taghreed M.

Iraqi Journal of Computers, Communications, Control and Systems Engineering

In this research the design of a Model Predictive Controller (MPC) is investigated for regulating Mean Arterial Pressure (MAP) by infusing the Sodium Nitro-Prusside (SNP) drug to the mathematical model of human patients during surgical operations where the blood pressure suffers from sudden rises due to multiple causes. The MPC is designed and compared with digital Proportional-Integral (PI) controller. MPC is chosen due to its known ability of estimating an optimal control action and dealing with input, state constraints and with disturbances. Simulation results for three patients' MAP models controlled by MPC and PI controllers that are designed for a …

Human Arm Simulation Based On Matlab With Virtual Enviroment, Mohammed Z., Abduladhem A. Ali, Abbas H. Miry

Iraqi Journal of Computers, Communications, Control and Systems Engineering

This work presents a novel simulation methodology applied to a human arm. It is aimed to allow the robotic system to perform complex movement operations of human arm. The human arm is represented by using virtual reality (VR). The work includes mathematical modeling of the direct kinematics ,inverse kinematic and the dynamics of the human arm .The model permits direct forward dynamics simulation, which accurately predicts hand position, also presents a solution to the inverse problem of determining set of joints angle to achieve a given position or motion. The method is implemented in the 3D space and uses the …

Who Does What: Collaboration Patterns In The Wikipedia And Their Impact On Article Quality, Jun Liu, Sudha Ram

Research & Publications

The quality of Wikipedia articles is debatable. On the one hand, existing research indicates that not only are people willing to contribute articles but the quality of these articles is close to that found in conventional encyclopedias. On the other hand, the public has never stopped criticizing the quality of Wikipedia articles, and critics never have trouble finding low-quality Wikipedia articles. Why do Wikipedia articles vary widely in quality? We investigate the relationship between collaboration and Wikipedia article quality. We show that the quality of Wikipedia articles is not only dependent on the different types of contributors but also on …

Study On Weight Loss And Moisture Regain Of Silk Cocoon Shells And Degummed Fibers From African Wild Silkmoths, Addis Teshome, S. K. Raina, F. Vollrath, J. M. Kabaru, J. Onyari, E. K. Nguku

All Peer-Reviewed Publications

A study was conducted to determine weight loss and moisture regain properties of silk cocoon shells, shell layers and degummed fibers of the four African wild silkmoths Anaphe panda, Argema mimosae, Epiphora bauhiniae and Gonometa postica and compare with the industry standard mulberry silkmoth, Bombyx mori. No. significant difference was observed between the moisture regain of the wild silk fibers after degumming. However, there were significant differences in weight loss and moisture regain between cocoon shells as well as shell layers. E. bauhiniae had the lowest weight loss and moisture regain of 23.19 and 5.64%, respectively while G. postica had …

Factors For Improved Fish Passage Waterway Construction, David N. Sillars, Hamid Moradkhani, Nicholas Tymvios, Trevor D. Smith

TREC Final Reports

Streambeds are important fish passageways in Oregon; they provide for the necessary habitats and spawning cycles of a healthy fish population. Oregon state law requires that hydraulic structures located in water properly provide fish passage. Increasingly stringent state and federal regulations apply to these fish passageways, and designers must become more cognizant of conditions over a range of flows to accommodate fish movement and avoid expensive structural failure of these passageways. Fish passage structures are built when roads cross streambeds and may include culverts, or bridges. When these structures are built, the streambeds are re-created using a technique called “roughened …

Yearnings: Stories Of Insecure Attachment And The Journey To Connect To God, John Bracy

Loma Linda University Electronic Theses, Dissertations & Projects

Utilizing grounded theory and the semi-structured interviews of25 participants, this study sought to understand how an insecure attachment affects one's relationship with God. Participants' stories suggested that: I) one's struggle to connect with God was a part of their struggle to connect with others; 2) that experiencing others as safe and responsive contributed to building a more secure attachment with God; and 3) that attachment is less a fixed style and more of an ongoing process: defined as gradual changes made by the participants towards the set-goal of feeling safe and secure. Four major processes were identified: I) finding what …

Family Environment Externalizing And Internalizing Behaviors Among Adolescents In St. Lucia, St. Clair P. Alexander

Loma Linda University Electronic Theses, Dissertations & Projects

The family is uniquely positioned either to positively or negatively influence the well-being, development, and adjustment of adolescents. There is a considerable body of research in the general literature associating the family environment with adolescent externalizing and internalizing behaviors of adolescents. St. Lucia, and the rest of the Caribbean, have distinctive cultural and familial habits and patterns that may influence adolescents' behavior. However, little or no attention has been given to assessing empirically the role that family dynamics may play in adolescents' behavior on the island of St. Lucia. The purpose of this study was to explore the relationship between …

Writing To Learn: Can Reflection Journals Be Used To Promote Self-Reflection And Learning?, Duan Ning, Magdeleine Lew, Henk G. Schmidt

Research Collection Lee Kong Chian School Of Business

The purpose of the present study was to evaluate whether there is evidence of reflection in student-written journals and to investigate whether students show improvements in their reflective skills through journal keeping. To that end, the reflection journals of 3460 first-year students enrolled in a polytechnic were studied by means of an automated coding procedure. Data used in the analyses were students' journals for an entire week, collected once at the beginning and again at the end of an academic year. Outcomes of the content analyses suggest that there is evidence of reflection in students' journals and that students reflected …

Situational Judgment Tests As A New Tool For Dental Student Selection, Tine Buyse, Filip Lievens

Research Collection Lee Kong Chian School Of Business

Cognitive tests are used to select students into dental school, yet cognitive predictors explain only part of the variance in academic performance. Therefore, interviews and personality tests are often used to measure noncognitive (e.g., interpersonal) characteristics. Recently, situational judgment tests (SJTs) have drawn attention since there is evidence that SJTs can be valid predictors in medical admission contexts. This study examines the validity of an SJT measuring interpersonal skills for predicting academic performance of dental students. Incremental validity over cognitive tests is also examined. In this study, 796 dental students who passed the admission exam for medical and dental students …

Rn181 Suppresses Hepatocellular Carcinoma Growth By Inhibition Of The Erk/Mapk Pathway, S Wang, X Huang, Y Li, H Lao, Et Al

School of Biomedical Sciences

UNLABELLED: The activation of oncogenes and the inactivation of tumor suppressor genes by mutations or chronic hepatitis virus infections play key roles in the pathogenesis of hepatocellular carcinoma (HCC). Here we report that RN181, a really interesting new gene finger domain-containing protein, was down-regulated in highly malignant cell lines and in tumor cells of 139 HCC clinical samples in comparison with adjacent normal liver tissues. The expression of RN181 was strongly associated with the pathological grade of HCC. Alterations of the expression of RN181 by retrovirus-transduced up-regulation and short hairpin RNA-mediated down-regulation demonstrated the function of RN181 as a tumor …

2011 June, Office Of Communications & Marketing, Morehead State University.

Morehead State Press Release Archive, 1961 to the Present

Press releases for June 2011.

Simulation Model Of Pacinian Corpuscle For Haptic System Design, Daniel Liu

Theses

With the increasing need for tactile feedback in Human Computer Interfaces used in robotics, medical, and mobile devices, there has been an increasing interest in the design of tactile sensors, displays, and complete haptic systems to transfer tactile information to users. These systems have improved users ability to work with remote tools or virtual environments, from enhancing the accuracy of tools like robotic surgery to improving user experiences in virtual reality systems. Despite many advances, the potential of these technologies to provide augmented or realistic sensations of touch is limited in part by the lack of understanding the complex mechanisms …

The Conservation And Habitat Ecology Of Antillean Manatees (Trichechus Manatus Manatus) In The Drowned Cayes Area Of Belize, Central America, Katherine Spencer Lacommare

Graduate Doctoral Dissertations

The Drowned Cayes area of Belize, Central America is regionally important for the conservation of Antillean manatees in the Caribbean (Lefebvre et al. 2001; Quintana-Rizzo & Reynolds 2008). These islands are increasingly threatened by human activities such as tourism, development and population growth. The objective of this dissertation is to evaluate manatee habitat use and status in this area. The 5 specific objectives are to examine manatee (1) distribution in the Drowned Cayes, (2) use of seagrass beds and forage selection, (3) resting habitat use and selection (4) response to disturbance, and (5) trends in abundance and to suggest a …

Random Ramblings - The Journal Is Dead: Long Live The Article, Robert P. Holley

School of Information Sciences Faculty Research Publications

Should the article stand alone, as the basic unit, apart from its container the journal?

Comparison Of Approximate Estimation Methods For Logistics Distribution Parameters, Omar Abdulmohsin Ali

Journal of Economics and Administrative Sciences

The goal beyond this Research is to review methods that used to estimate Logistic distribution parameters. An exact estimators method which is the Moment method, compared with other approximate estimators obtained essentially from White approach such as: OLS, Ridge, and Adjusted Ridge as a suggested one to be applied with this distribution. The Results of all those methods are based on Simulation experiment, with different models and variety of sample sizes. The comparison had been made with respect to two criteria: Mean Square Error (MSE) and Mean Absolute Percentage Error (MAPE).

Smoothly Varying Affine Stitching, Wen-Yan Lin, Siying Liu, Yasuyuki Matsuhita, Tian-Tsong Ng, Loong-Fah Cheong

Research Collection School Of Computing and Information Systems

Traditional image stitching using parametric transforms such as homography, only produces perceptually correct composites for planar scenes or parallax free camera motion between source frames. This limits mosaicing to source images taken from the same physical location. In this paper, we introduce a smoothly varying affine stitching field which is flexible enough to handle parallax while retaining the good extrapolation and occlusion handling properties of parametric transforms. Our algorithm which jointly estimates both the stitching field and correspondence, permits the stitching of general motion source images, provided the scenes do not contain abrupt protrusions.