Digital Commons Network^™

Effects Of Non-Planar Distortions In Porphyrin Compounds On Their Properties And Functionality, Raid Haddad

Chemical and Biological Engineering ETDs

Porphyrins and related compounds are ubiquitous in nature, performing diverse functions including solar energy transduction, electron transport, molecular transport and storage, and catalysis. Due to their unique photophysical and chemical properties, they are excellent candidates for application as photosensitizers, catalysts, photocatalysts, molecular electronics and opto-electronics. Several properties of porphyrins are sensitive to small variations in their structure, and this dissertation investigates the effects of out-of-plane distortions of the macrocycle on optical properties, reactivity to axial ligands, and substituent rotation. The structure-functions relationships are examined using molecular simulations, UV-visible absorption spectroscopy, resonance Raman spectroscopy, and normal-coordinate structural decomposition (NSD) analysis of …

Use Of Fluorescent Micropsheres To Measure Coronary Flow Reserve In Rat Animal Model, Riddhi Harsh Shah

Theses

Heart attacks result from reduced or blocked blood flow through major coronary arteries, resulting in permanent damage to heart muscle. Coronary blood flow (CBF) is thus important to measure in experimental animal models of heart disease. A standard method to measure CBF uses tracer microspheres (Ø = 15 µm) injected into the left ventricle that flow through coronary arteries but cannot pass through capillaries and so become trapped in heart muscle. Previously, radioactive or colored microspheres have quantified the number of tracers trapped in the muscle. Fluorescent microspheres offer a more recent and more sensitive measurement mode. However, fluorescent microspheres …

Irrigator And Springflow Response To A Dry Year Option For The Edwards Aquifer, Keith O. Keplinger, Bruce A. Mccarl, Manzoor E. Chowdhury, Ronald D. Lacewell

Journal of Contemporary Water Research and Education

No abstract provided.

Management Of The Edwards Aquifer Region - How The Endangered Species Act Influenced Action, Glenn Longley, Wayne R. Jordan

Journal of Contemporary Water Research and Education

No abstract provided.

The Edwards Aquifer: Conflicts Surrounding Use Of A Regional Water Resource, Herbert W. Grubb

Journal of Contemporary Water Research and Education

No abstract provided.

Legal Impediments To Integrated Water Resource Management: Lessons From The Edwards, Pete Schenkkan

Journal of Contemporary Water Research and Education

No abstract provided.

Foreword, Wayne R. Jordan

Journal of Contemporary Water Research and Education

No abstract provided.

Percobaan Sintesis 4-(4-Metoksibenzilidena) 2-Metiloksazol-5-On Dari Asetilglisin Dan 4-Metoksibenzaldehid, Arif Arrahman, Hayun Hayun, Arry Yanuar

Majalah Ilmu Kefarmasian

Compound 4-(4-methoxybenzylidene)-2-methyloxazole-5-one was one of oxazolone moety derivative. Oxazolones had several different pharmacological activity depend on substituent which was bonded to oxazolone ring. Oxazolones was an important precursor for synthesizing several compounds which had pharmacological activity. For that reason, experiment to synthesize 4-(4-methoxybenzylidene)-2-methyloxazole-5-one from acetyl- glicine and 4-methoxybenzaldehyde as an oxazolone derivative become necessary. Com- pound 4-(4-methoxybenzylidene)-2-methyloxazole-5-one was synthesized over two step of reaction. First step was reacted glycine with acetic anhydride in acidic environment yielded acetylglycine. Second step was reacted acetylglycine with 4-methoxybenzaldehyde yielded 4-(4-methoxybenzylidene)-2-methyloxazole-5-one. The product, which was collected in every step, was purified by washing and recrystalization …

Efek Nefroprotektif Infus Daun Sukun (Artocarpus Altilis (Park.) Fsb.) Pada Tikus Jantan Yang Diinduksi Karbon Tetraklorida, Rianti Adi Cahyaningsih, Azizahwati Azizahwati, Dadang Kusmana

Majalah Ilmu Kefarmasian

Renal dysfunction can be caused by several factors, including hypertension, urinary tract obstruction, autoimmune disorders, urinary tract infection, diabetes mellitus, consumption of drugs that affect nephrotoxic and antibiotic from aminoglycoside class. Breadfruit leaves (Artocarpus altilis (Park.) Fsb.) is a traditional plant that hasbeen used empirically to treat kidney diseases. The research has been done to figure out the nephroprotective effect of breadfruit leaves infusion on white male rats strain Sprague-Dawley previously induced by carbon tetrachloride. There were 25 rats which were divided randomly into five groups. Group I which was the normal control group received CMC 0,5%. Group II which …

Faculty Senate Summarized Minutes, 8/30/2011, Unm Faculty Senate

Faculty Senate Meeting Minutes, 1920 - 2013

No abstract provided.

Gc-Content Normalization For Rna-Seq Data, Davide Risso, Katja Schwartz, Gavin Sherlock, Sandrine Dudoit

U.C. Berkeley Division of Biostatistics Working Paper Series

Background: Transcriptome sequencing (RNA-Seq) has become the assay of choice for high-throughput studies of gene expression. However, as is the case with microarrays, major technology-related artifacts and biases affect the resulting expression measures. Normalization is therefore essential to ensure accurate inference of expression levels and subsequent analyses thereof.

Results: We focus on biases related to GC-content and demonstrate the existence of strong sample-specific GC-content effects on RNA-Seq read counts, which can substantially bias differential expression analysis. We propose three simple within-lane gene-level GC-content normalization approaches and assess their performance on two different RNA-Seq datasets, involving different species and experimental designs. …

The Valles Caldera: Recreationists' Perspectives On Access And Management, Matt Gagnon

Geography ETDs

With the public acquisition of Valles Caldera National Preserve in 2000, Congress granted management to a Board of Trustees, a unique experiment in public land management. Ten years into the experiment, the trust model has been failing to meet certain management objectives and is under pressure by outdoor recreationists to provide greater public access to this treasured piece of land in New Mexico. Pressure has become so great that the United States Senators from New Mexico have introduced legislation, the Valles Caldera National Preserve Management Act, which would transfer management to the National Park Service. To address this blossoming issue, …

Uji Penghambatan Tirosinase Dan Stabilitas Fisik Sediaan Krim Pemutih Yang Mengandung Ekstrak Kulit Batang Nangka (Artocarpus Heterophyllus), Ninin Kartika Juwita, Joshita Djajadisastra, Azizahwati Azizahwati

Majalah Ilmu Kefarmasian

The cortex of jackfruit (Artocarpus heterophyllus) contains some flavonoids which have activity as tyrosinase inhibitors. This compound can inhibit the oxidation of l-tyrosine and levodopa in the mechanism of melanogenesis. The extract of jackfruit cortex formulated into creams differentiated by the extract concentration of 1,5% and 2,0%. Physical stability test was conducted with storing the creams at three different temperatures, 7 ± 2°, 27 ± 2°, and 40±2°C respectively. Centrifugal tests and cycling test was also performed on both cream. Tyrosinase inhibitory activity measurement was done by in vitro studies with measuring dopachrome. The result showed that both of formulations …

Formulasi Sediaan Granul Mukoadhesif Kombinasi Ekstrak Kulit Batang Mimba (Azadirachta Indica A. Juss) Dan Kunyit (Curcuma Domestica Val.), Sutriyo Sutriyo, Khairunnisya Khairunnisya, Abdul Mun’Im

Majalah Ilmu Kefarmasian

Neem bark (Azadirachta indica A.Juss) and turmeric (Curcuma domestica Val.) extracts have been found posses gastroprotective effect so that they are used in the treatment of gastric ulcer. Administration of combination of both extracts can give synergistic effect so that the administration dose can be reduced. In this research, combination of neem bark and turmeric extracts were formulated as mucoadhesive granules to improve their effectivenesses by increasing the residence time of dosage form in the stomach. Mucoadhesive granules were prepared by wet granulation method in six formulas using HPMC, Carbopol, and combination of HPMC and Carbopol as mucoadhesive polymers. Granules …

Investigating Evidence Of High Frequency Glacial Eustacy In The Lower Mississippian (Tournasian) Lodgepole Formation Of Southwest Montana : Insights From Conodont Oxygen Isotopes, Zachary Wallace

Earth and Planetary Sciences ETDs

This study focuses on high-frequency, subtidal-carbonate cycles (1-8 m thick) within the Woodhurst Member of the Lower Mississippian Lodgepole Formation of southwest Montana. We combined conodont-oxygen isotopes (δ18Oapatite¬) and carbonate-carbon isotopes (δ13Ccarb) with cyclostratigraphy of Woodhurst cycles to test the hypothesis that the cycles developed in response to glacial eustasy, evaluate the timing and initiation of the Late Paleozoic Ice Age (LPIA), and to better understand the carbon budget in response to cycle formation. δ18Oapatite trends across targeted cycles support the hypothesis of glacial eustatic origins along with cooling surface seawater temperatures. High-resolution δ13Ccarb analysis of whole-rock limestones within eleven …

Applying Numerical Sediment Transport Models To Examine River Restoration Sustainablilty At The Rio Grande Nature Center, New Mexico, Kyle Shour

Civil Engineering ETDs

Much of the Middle Rio Grande has severely degraded since 1930 when flood control institution began (Scurlock 1998). Since that time, additional anthropogenic stressors have continued to cause the river to incise and narrow and have harmed the ecological health of the system. As a result, many different entities have developed restoration projects along the Middle Rio Grande. These projects are often localized, small scale features that promote native vegetation establishment and improve habitat for endangered species without removing flood protection measures. One such feature is the Rio Grande Nature Center (RGNC) Habitat Restoration project. The project consists of removing …

Flyer News, Vol. 59, No. 2 (Aug. 30, 2011), University Of Dayton

Flyer News

Student-run newspaper of the University of Dayton.

Ccr3 Inhibition For Ocular Angiogenesis And Macular Degeneration, Jayakrishna Ambati

Ophthalmology and Visual Science Faculty Patents

Provided are methods and compositions for the treatment or prevention of ocular angiogenesis and neovascularization. Administration of inhibitors of the CCR3 receptor or its ligands eotaxin (CCL11), eotaxin-2 (CCL24) or eotaxin-3 (CCL26) inhibits ocular angiogenesis.

Monitor Newsletter August 30, 2011, Bowling Green State University

Monitor

Official Publication of Bowling Green State University for Faculty and Staff

Generation Of Transgenic Human Soluble Amyloid Precursor Protein Alpha Expressing Mice, Jun Tan, William Nikolic, Huyan Hou

USF Patents

The present invention relates to a novel animal model for neurological degenerative diseases, especially autism, relating to overexpression of human secreted APP-alpha. This novel animal model exhibits several aspects of amyloidopathy. The present invention also relates to a method for producing the double transgenic animals, to cells and cell lines derived from these animals. Moreover, a method for the evaluation of the in vivo effects of a test compound on secreted APP-alpha expression and autism pathology in these animals is provided.

Ship-Deficiency To Increase Megakaryocyte Progenitor Production, William G. Kerr, Caroline Desponts, Lia Elena Perez

USF Patents

The invention concerns a method for increasing megakaryocyte and megakaryocyte progenitor numbers in vitro or in vivo by suppressing SH2-containing inositol-5-phosphatase (SHIP) function in megakaryocytes or megakaryocyte progenitors expressing the SHIP gene. SHIP function can be suppressed by administering an interfering RNA, or other SHIP inhibitor, to the megakaryocytes or megakaryocyte progenitors in vitro or in vivo.

Compositions And Methods For Detecting Intracellular Glucose And Analogs Thereof, Denise R. Cooper, Niketa A. Patel

USF Patents

The subject invention pertains to nucleic acid constructs for post-transcriptional control of expression of a polynucleotide encoding a protein in a cell, wherein the constructs include a metabolite responsive instability element such as the glucose-regulated mRNA instability element. The subject invention further pertains to host cells and vectors comprising the nucleic acid constructs of the invention, as well as probes, methods, and kits for detecting metabolite responsive instability elements or mutations thereof. The present invention further concerns a reporter vector useful for detecting intracellular glucose and glucose-analogs, host cells genetically modified with the reporter vector, and methods for detecting intracellular …

Characterizing The Local Food Environment In Albuquerque, New Mexico: A Dual Perspective Of Retailer And Consumer, Kathryn Lenzer

Geography ETDs

This research used local produce as a way to investigate the construction and meaning of the local food environment by food retailers and consumers in Albuquerque, New Mexico. The research consisted of three components. First, the observed local food environment was defined through store surveys that were conducted in 193 food retail outlets and farmers markets in the Albuquerque study area. These surveys were performed in order to collect information, through signage and other advertising materials, about how retailers defined 'local' produce. The subsequent qualitative text analysis on these materials allowed for several themes to emerge that characterized the observed …

The Sun Star (August 30, 2011), N/A N/A

Sun Star

No abstract provided.

The Current Volume 22 : Issue 2, Nova Southeastern University

Student Newspapers

No abstract provided.

Structural Characterization Of Metal Binding In Metallo-Β-Lactamases Using X-Ray Absorption Spectroscopy, Robert M. Breece

Chemistry and Chemical Biology ETDs

In an effort to probe the structure and mechanism of metallo-β-lactamases, the metal-binding behaviors of several enzymes were studied using EXAFS (Extended X-ray Absorption Fine Structure). Three members of the metallo-β-lactamase subclass B1, BcII from Bacillus cereus, Bla2 from Bacillus anthracis and CcrA from Bacillus fragilis, were compared to examine metal-binding behavior within a subclass. Each system exhibits different metal-binding behavior including cooperative binding (BcII), sequential binding (CcrA), and differential binding between zinc(II) and cobalt(II) forms (Bla2). The metal-binding behavior of subclass B3 of L1 from Stenotrophomonas maltophilia was explored with RFQ (rapid-freeze quenched) EXAFS and site selective metal …

Separation Of River Network–Scale Nitrogen Removal Among The Main Channel And Two Transient Storage Compartments, Robert J. Stewart, Wilfred M. Wollheim, Michael N. Gooseff, Martin A. Briggs, Jennifer M. Jacobs, Bruce J. Peterson, Charles S. Hopkinson

Faculty Publications

Transient storage (TS) zones are important areas of dissolved inorganic nitrogen (DIN) processing in rivers. We assessed sensitivities regarding the relative impact that the main channel (MC), surface TS (STS), and hyporheic TS (HTS) have on network denitrification using a model applied to the Ipswich River in Massachusetts, United States. STS and HTS connectivity and size were parameterized using the results of in situ solute tracer studies in first‐ through fifth‐order reaches. DIN removal was simulated in all compartments for every river grid cell using reactivity derived from Lotic Intersite Nitrogen Experiment (LINX2) studies, hydraulic characteristics, and simulated discharge. Model …

Volume 109, Number 1 - Tuesday, August 30, 2011, Saint Mary's College Of California

The Collegian

No abstract provided.

Metaphors: Universal, Specific, And Public, Deli Nirmala

Bahasa dan Seni: Jurnal Bahasa, Sastra, Seni, dan Pengajarannya

Metaphors in written discourse, such as letters using bahasa Indonesia, can be derived from the metaphorical expressions used by writers to editors, showing conceptualization based on what they experience, feel, and think in their lives. This paper aims to find out the universality of the concepts shown by the metaphors and the users employing them. Using nonparticipant observation with a note-taking technique, the data are collected and selected purposively. Through distributional, referential, reflective introspective, and abductive inferential methods, the data are analyzed. The results indicate that metaphors can be grouped into universal, specific, and public types based on the universality …

Pengembangan Reading Box Untuk Meningkatkan Minat Baca Mahasiswa, Sri Andreani, Utari Praba Astuti

Bahasa dan Seni: Jurnal Bahasa, Sastra, Seni, dan Pengajarannya

Due to the unavailability of materials for the Reading II subject, this study attempts to develop a reading box material which consists of 80 units of 400–500 words. Each unit contains an introduction, questions, readings, answer keys, reflections, and monitoring books. This reading box enables students to practice reading extensively and independently. This material was developed through several stages: planning, exploration, product development, validation, and laminating. During validation, revisions were made to the questions, readings, answer keys, reflections, illustrations, layout, the title, and the monitoring book. However, the results of the questionnaire on the validation process show that the material …