Digital Commons Network^™

Uncovering New Functions For Micrornas In Caenorhabditis Elegans, Allison L. Abbott

Biological Sciences Faculty Research and Publications

In the race to understand microRNA (miRNA) functions in development and physiology, Caenorhabditis elegans investigators were the first out of the gate with the cloning and analysis of the lin-4 and let-7 miRNAs [1,2]. The starting point of strong, penetrant loss of function phenotypes facilitated these advancements. However, subsequent functional analysis of miRNAs in C. elegans was hampered by the lack of easily observable loss-of-function phenotypes [3]. There are several possible models to account for this observation. First, redundancy between related miRNAs can account for the absence of phenotypes in mutants missing individual miRNA genes [4,5]. Second, miRNAs may also …

Capturing The Judiciary: Carhart And The Undue Burden Standard, Khiara Bridges

Faculty Scholarship

In Planned Parenthood of Southeastern Pennsylvania v. Casey, the Supreme Court replaced the trimester framework, first articulated nineteen years earlier in Roe v. Wade, with a new test for determining the constitutionality of abortion regulations — the “undue burden standard.” The Court’s 2007 decision in Gonzales v. Carhart was its most recent occasion to use the undue burden standard, as the Court was called upon to ascertain the constitutionality of the Partial-Birth Abortion Ban Act, a federal statute proscribing certain methods of performing second- and third-trimester abortions. A majority of the Court held that the regulation was constitutionally permissible, finding …

September 13, 2011, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

Required Reading: Using Ebooks And Mobile Devices To Support The Educational Experience, Barbara Glackin, Roy Rodenhiser

Mobile Learning Symposium

How can we integrate eBooks into the classroom? Which mobile device is the best for student learning? Learn from rigorous assessment findings from a pilot project that took place last year. The students who participated read eBooks on iPads and netbooks, evaluating each to learn the best uses of each device. This presentation will focus on their findings, and how they were able to accomplish this incredible project!

The Communicator, September 12, 2011, Bronx Community College

The Communicator

The Communicator newspaper published on September 12, 2011.

Cseas Weekly Bulletin (September 12, 2011), Center For Southeast Asian Studies

CSEAS Bulletin

No abstract provided.

The Statesman, V. 55, I. 02, Stony Brook University

Stony Brook Statesman-Sucolian

v. 55, i. 02

Current, September 12, 2011, University Of Missouri-St. Louis

Current (2010s)

No abstract provided.

The Chanticleer, 2011-09-12, Coastal Carolina University

The Chanticleer Student Newspaper

The editorially independent student produced weekly newspaper of Coastal Carolina University.

Beta-Lysine Discrimination By Lysyl-Trna Synthetase, Marla S. Gilreath, Hervé Roy, Tammy J. Bullwinkle, Assaf Katz, Michael Ibba, William Wiley Navarre

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Elongation factor P is modified with (R)‐β‐lysine by the lysyl‐tRNA synthetase (LysRS) paralog PoxA. PoxA specificity is orthogonal to LysRS, despite their high similarity. To investigate α‐ and β‐lysine recognition by LysRS and PoxA, amino acid replacements were made in the LysRS active site guided by the PoxA structure. A233S LysRS behaved as wild type with α‐lysine, while the G469A and A233S/G469A variants decreased stable α‐lysyl‐adenylate formation. A233S LysRS recognized β‐lysine better than wildtype, suggesting a role for this residue in discriminating α‐ and β‐amino acids. Both enantiomers of β‐lysine were substrates for tRNA aminoacylation by LysRS, which, together with …

The Collegian (2011-09-12), Rene Cardona Jr.

UTB/TSC Archives - The Collegian [Newspaper]

Vol. 64. No. 4

Thinspiration: New Media's Influence On Girls With Eating Disorders, Victoria Stonebridge

Theses and Dissertations

The use of thinspiration and social networking by girls with eating disorders on social media websites and through user-generated content aids the disease in general. The purpose of this research exploration is to find out how influential these specific forms of new media are on girls with eating disorders. A content analysis will serve as the primary quantitative measure for this study. A survey, via SurveyMonkey.com, will be used to find what kind of impact new media has on girls with eating disorders. The researcher will also conduct a personal interview with an expert in the field of psychology and …

Crow's Nest, September 12, 2011, Crow's Nest Staff

Crow's Nest

The September 12, 2011, issue of the Crow's Nest.

Efficient Graph Algorithms Based On Color Coding Method, Kun Wang

Student Theses and Dissertations

Graph theory is the study of graphs in theoretical computer science. Graphs are mathematical models used to describe pairwise relations between objects from a certain collection. Many practical problems can be modeled as graphs problems, so it is of great importance to develop efficient graph algorithms for different graph problems based on high-throughput data. In this work, we study several important bioinformatics problems which are modeled as problems on weighted graphs, bounded local tree-width graphs, bounded-degree graphs, or mixed graphs etc. We design very efficient algorithms based on the color-coding method for these graph problems. We also apply the idea …

Nick Piediscalzi Interview, Professor Emeritus Department Of Religion, Wright State University, Pablo Banhos, Nick Piediscalzi

Wright State University Retirees Association Oral History Project

Pablo Banhos interviewed Nick Piediscalzi on September 12, 2011 about the founding of Wright State University and the development of the Department of Religion. In the interview Mr. Piediscalzi discusses his career and his decision to come to Wright State.

After speaking with Pablo Banhos, Nick Piediscalzi created a second video on September 24, 2011 to act as an addendum to the original interview. In this video he expands on various topics, including members of his department and other memories that came to him after the initial interview.

Understanding Formation And Transport Of Amorphous Iron Oxyhydroxides In Porous Media Using Microfluidic Flow Cells- A Novel Method To Study Freshwater Iron Cycling, Neha A. Ghaisas

Master's Theses

The ground water and surface water interface (GSI or Hyporheic zone) is a spatially- and temporally-fluctuating biogeochemical transition zone connecting these two distinct hydrological components. The mixing zone is characterized by a near neutral pH, ambient temperature and a sharp oxygen concentration which in turn has deep impact on the iron cycling and thus the fate of contaminants in the water column. We constructed an experimental micromodel that to observe key processes that affect biogeochemical iron cycling in the fresh water interface zones where the oxic surface water mixes with Fe (II) rich underlying ground water. The flow cell was …

Board Of Directors Meeting Minutes (September 12, 2011), Dmacc

Board of Directors Meeting Minutes

This file contains the minutes from the Des Moines Area Community College Board meeting held on September 12, 2011.

Isoflurane's Effect On Protein Conformation As A Proposed Mechanism For Preconditioning, Michelle R. Baker, Sean K. Benton, Christopher S. Theisen, Chad A. Mcclintick, Eugene E. Fibuch, Norbert W. Seidler

Faculty and Staff Publications

Persistent alteration of protein conformation due to interaction with isoflurane may be a novel molecular aspect of preconditioning. We preincubated human serum albumin with isoflurane, dialyzed to release agent, and assessed protein conformation. Susceptibility to chemical modification by methylglyoxal and nitrophenylacetate was also examined. Isoflurane had a persistent effect on protein conformation. An increase in the susceptibility of surface residues to chemical modification attended this change in conformation. Modification of isoflurane-treated HSA included intra- and intersubunit cross-linking that may be a consequence of anesthetic-induced changes in multimeric subpopulations. This irreversible effect of isoflurane may represent a mechanism for preconditioning.

Effects Of Prescribed Burning On Vegetation And Swainson’S Warbler Space Use Patterns In Eastern Arkansas, Jeremy Lewis Everitts

Student Theses and Dissertations

The Swainson’s warbler Limnothlypis swainsonii) is a species of conservation concern throughout the southeastern U.S. An understanding of Swainson’s warbler habitat requirements has been documented, although little is known about how prescribed burning may improve or potentially negatively impact their populations. To learn more about the ecology of this secretive species and understand the effects of management on habitat use patterns, I studied the effects of prescribed burning on a population of Swainson’s warblers in the St. Francis National Forest in Arkansas. With the help of coworkers, I radio−tracked 45 Swainson’s warblers and collected habitat data at 1,043 sites within …

A Simple Ontology For The Analysis Of Terrorist Attacks, Matthew D. Turner

Electrical & Computer Engineering Technical Reports

No abstract provided.

Mutational Analysis Of Photosystem I Of Synechocystis Sp. Pcc 6803: The Role Of Four Conserved Aromatic Residues In The J-Helix Of Psab., Wu Xu, Yingchun Wang, Eric Taylor, Amelie Laujac, Liyan Gao, Sergei Savikhin, Parag R. Chitnis

Department of Physics and Astronomy Faculty Publications

Photosystem I is the light-driven plastocyanin-ferredoxin oxidoreductase in the photosynthetic electron transfer of cyanobacteria and plants. Two histidyl residues in the symmetric transmembrane helices A-j and B-j provide ligands for the P700 chlorophyll molecules of the reaction center of photosystem I. To determine the role of conserved aromatic residues adjacent to the histidyl molecule in the helix of B-j, we generated six site-directed mutants of the psaB gene in Synechocystis sp. PCC 6803. Three mutant strains with W645C, W643C/A644I and S641C/V642I substitutions could grow photoautotrophically and showed no obvious reduction in the photosystem I activity. Kinetics …

Agronomy / Land Use - Purdue University, Jake R. Carlson

Data Curation Profiles Directory

This data curation profile covers a data set generated by a graduate student studying the growth of switch grass on different types of land and evaluating the performance of the switch grass in thermo-chemical conversion for bio energy. He is particularly interested in how the switch grass planted on land suited for annual crop growth interacts with these annual crops. The data management issues include the separation of his data in Excel files from his physical lab notebook. He has shared his data previously with another graduate student from a different discipline. However, because they came from different disciplinary backgrounds, …

Pipkiγ Regulates Focal Adhesion Dynamics And Colon Cancer Cell Invasion, Zhaofei Wu, Xiang Li, Manjula Sunkara, Heather Spearman, Andrew J. Morris, Cai Huang

Markey Cancer Center Faculty Publications

Focal adhesion assembly and disassembly are essential for cell migration and cancer invasion, but the detailed molecular mechanisms regulating these processes remain to be elucidated. Phosphatidylinositol phosphate kinase type Iγ (PIPKIγ) binds talin and is required for focal adhesion formation in EGF-stimulated cells, but its role in regulating focal adhesion dynamics and cancer invasion is poorly understood. We show here that overexpression of PIPKIγ promoted focal adhesion formation, whereas cells expressing either PIPKIγ^K188,200R or PIPKIγ^D316K, two kinase-dead mutants, had much fewer focal adhesions than those expressing WT PIPKIγ in CHO-K1 cells and HCT116 colon cancer cells. Furthermore, …

Combinatorial Catalysis Assisted By A Visible Enzymatic Beacon In Real Time: New Synthetically Versatile (Pseudo)Halometalation/Carbocyclizations, Jacob A. Friest, Sylvain Broussy, Woo Jin Chung, David B. Berkowitz

David Berkowitz Publications

Combinatorial approaches to catalysis have made an impact in targeted transformation development, including Ag-mediated carbene insertion,^[1] Sc-pybox-based asymmetric cyclopropanation,^[2] and Rh/Ir-based asymmetric hydrogenation.^[3] Useful design elements have emerged from these studies, e.g. the value of ligand self assembly,^[4] or of the inclusion of peptide-like structural elements^[5],[6],[7] in building ligand arrays. Efficient screening methods are of paramount importance for such efforts. Methods based on fluorescence,^[8] REMPI^,[9] MS,^[10] NMR,^[11] and IR thermography^[12] have appeared. A chromophore may be installed into the substrate^[13] or product^[14] of the reaction under study. Alternatively, …

Medical School Watercooler Newsletter - September 11, 2011, Lindsey Lyle

Watercooler Newsletter

This is the September 11, 2011 edition of the Frederick P. Whiddon College of Medicine's newsletter, Watercooler

Contents Include

• Press-Register Ad To Feature 'Top Docs'
• Dr. Dean Parmelee to Present Two Workshops

• Mark Your Calendars - Gulf Coast Liver Support Group Meeting

• Basic Medical Sciences Graduate Program Student Receives Edwin R. Hughes Award

• Interventional Neurologist to Discuss New Treatments for Stroke

• Free Community Lecture on Weight Loss

The "Human Mental State Multiple Realizability In Silicon Thesis" Is False: An Argument Against Computational Theories Of Consciousness, Matthew Stuart Piper

Theses

In this paper, I argue that all computational theories of consciousness (CTCs) fail. CTCs hold that the right kind of computation is sufficient for the instantiation of consciousness. Given the widely-recognized importance of his work, I will use David J. Chalmers’ Thesis of Computational Sufficiency as a paradigm case. I will argue that it fails for a reason that can be formalized as a general problem plaguing any CTC: the medium-independent properties (MIPs) constitutive of computational processes are insufficient to instantiate the medium-dependent properties (MDPs) constitutive of consciousness. MIPs, like graphemes, are properties whose causal role (e.g., symbolic meaning) does …

Usfsp Added As Site For Lsat, Act And Sat Exams, September 11, 2011, Melanie Marquez

USF St. Petersburg Campus News and Press Releases

No abstract provided.

Uab Scientists Find Link Between Seizures And Brain Tumors, Alicia Rohan

Browse All News

No abstract provided.

The Preparation And Characterization Of Some Metal Complexes With Tridentate Ono Ligand Derived From Phenyl Hydrazine, Mahmoud S. Muter

Baghdad Science Journal

The phenyl hydrazine was react readily with acetic acid chloride in [1:2] ratio in alkyl of ethanolic solution, and refluxe for five hours to produce a new ligand of (N-Carboxymethyl-N-phenyl-hydrazino)-acetic acid [H2L].

The Cultural Politics Of Wmd Terrorism In Post-Cold War America, Harold Williford

Re-visioning Terrorism

Terrorism’s definition is hotly debated and notoriously problematic. The resulting instability of counterterrorism and counterterrorist identity, however, is less often explored. This paper analyzes the prehistory of the War on Terror to explore how the meaning and associations attributed to terrorism by counterterrorists in the 1990s reflect the latter’s priorities, agenda, and anxieties. Prevalent ahistorical post-Cold War representations of terrorism involving weapons of mass destruction (WMD) as a “new” threat indicate that WMD-wielding terrorists functioned to justify the continued existence of the American national security state after the Soviet Union collapsed. Close readings of Rainbow Six, a Tom Clancy …