Digital Commons Network^™

Wave-Function Functionals For The Density, Marlina Slamet

Physics Faculty Publications

We extend the idea of the constrained-search variational method for the construction of wave-function functionals ψ[χ] of functions χ. The search is constrained to those functions χ such that ψ[χ] reproduces the density ρ(r) while simultaneously leading to an upper bound to the energy. The functionals are thereby normalized and automatically satisfy the electron-nucleus coalescence condition. The functionals ψ[χ] are also constructed to satisfy the electron-electron coalescence condition. The method is applied to the ground state of the helium atom to construct functionals ψ[χ] that reproduce the density as given by the Kinoshita correlated wave function. The expectation …

Professional Product Review Vol. 6 No. 1, American Dental Association, Council On Scientific Affairs

Professional Product Review

A user-friendly newsletter from the ADA Council on Scientific Affairs offering scientifically sound, unbiased, and clinically relevant information to member dentists about professional dental products tested by the ADA. This collection is historical and may not reflect current standards. For up-to-date information contact the ADA.

Characterization Of Poly (Rc) Binding Protein (Pcbp2) And Frataxin, Sudipa Ghimire-Rijal

Wayne State University Theses

Iron is a micronutrient that acts as a cofactor in many prosthetic groups involving itself in almost every biological process. Iron is the key component in our body fluid, flowing in our veins all the time. Iron deficiency disorders affects more than 9 million people worldwide. Similarly, a high level of iron is associated with various disorders which suggest that in order for body to function properly level of iron should be tightly regulated. Many iron binding proteins help in maintaining cellular iron homeostasis by keeping iron in reduced form.

Working on the hypothesis that Poly (rC) Binding Protein family …

Social Workers' Knowledge And Attitudes About Treating Children With Attention Deficit Hyperactivity Disorder, Angelah Dawn Gomez

Wayne State University Theses

The current research seeks to understand how social work students and social work professionals increase their knowledge about AD/HD and how they formulate their attitudes about the disorder. The literature provided illustrates the many components of AD/HD risks, etiology, treatments, and professional opinions about the disorder. AD/HD is one of the most studied childhood mental health disorders in the nation. However, there is little research providing insight to social workers' knowledge and attitudes about the disorder. This is especially alarming because social workers are one of the largest professional populations to provide mental health services to children and their families. …

Novel Inhibitors Of Lysine Specific Demethylase 1 As Epigenetic Modulators, Michael Crowley

Wayne State University Theses

The recently discovered enzyme lysine-specific demethylase 1 (LSD1) plays an important role in the epigenetic control of gene expression, and aberrant gene silencing secondary to LSD1 over expression is thought to contribute to the development of cancer. We recently reported a series of (bis)guanidines and (bis)biguanides that are potent inhibitors of LSD1, and induce the re-expression of aberrantly silenced tumor suppressor genes in tumor cells in vitro. We now report a new series of isosteres that are also potent inhibitors of LSD1. These compounds induce increases in methylation at the histone 3 lysine 4 (H3K4) chromatin mark, a specific target …

The Human Right To Health And Hiv/Aids: South Africa And South-South Cooperation To Reframe Global Intellectual Property Principles And Promote Access To Essential Medicines, Erika George

Indiana Journal of Global Legal Studies

The HIV/AIDS pandemic has had a devastating and disproportionate impact in countries of the Global South. The experience of an individual infected with HIV in Africa is very different than that of an individual infected with HIV in America. Life expectancy varies sharply. The ability or inability to access medicines essential for treatment accounts for much of the variance. This article examines how the rhetoric of human rights used in the context of South Africa's AIDS crisis resonated across the Global South, resulted in a powerful social movement for access to medicines, and contributed to important changes in international intellectual …

African Customary Law, Customs, And Women's Rights, Muna Ndulo

Indiana Journal of Global Legal Studies

The sources of law in most African countries are customary law, the common law and legislation both colonial and post-independence. In a typical African country, the great majority of the people conduct their personal activities in accordance with and subject to customary law. Customary law has great impact in the area of personal law in regard to matters such as marriage, inheritance and traditional authority, and because it developed in an era dominated by patriarchy some of its norms conflict with human rights norms guaranteeing equality between men and women. While recognizing the role of legislation in reform, it is …

A Domain Aware Genetic Algorithm For The P-Median Problem, Dennis Vickers

CCAC Theses and Dissertations

The p-median problem is an NP-complete combinatorial optimization problem often used in the fields of facility location and clustering. Given a graph with n nodes and an integer p < n, the p-median problem seeks a set of p medians such that the sum of the distances of the n nodes from their nearest median is minimized. This dissertation develops a genetic algorithm that generates solutions to the p-median problem that improves on previously published genetic algorithms by implementing operators that exploit domain specific information. More specifically, this GA explores the following:

(1) The advantages of using "good" solutions generated using extant heuristics in the initial generation of chromosomes.

(2) The effectiveness of a crossover operation that exchanges centers in the same neighborhood rather than exchanging arbitrarily chosen subsets of centers.

(3) The efficacy of using a biased mutation operator that favors replacing existing medians from less fit chromosomes with non-median nodes from the same neighborhood as the median being replaced.

Using published …

Melting Kinetics In Microgravity, Martin E. Glicksman

Aerospace, Physics, and Space Science Faculty Publications

We analyzed the large data archive obtained from microgravity experiments called the Isothermal Dendritic Growth Experiment (IDGE). The final orbital mission of the IDGE allowed streaming of real-time video of crystal growth and melting in low-Earth orbit of high-purity pivalic acid anhydride (PVA). Melting kinetics was observed in detail for the first time under microgravity conditions. Normally, terrestrial gravity precludes observation and analysis of conduction-limited melting by stimulating buoyancy flows and inducing collapse of the solid-liquid structure. The initial dendritic mushy zone melts under steady heating into isolated crystallite clusters that remain stationary within the melt, and eventually shrink toward …

Novel Optical Remote Sensing Technology For Prediction Of Harmful Algal Blooms, Elizabeth Tobin

Link Foundation Ocean Engineering and Instrumentation Fellowship Reports

Harmful Algal Blooms (HABs) are outbreaks of planktonic algae that threaten public health, degrade aquatic ecosystems and cause major economic losses. Most HABs are detected only after they reach an advanced stage, when they have already caused significant ecological and economic damage. However, many HAB-forming species have two distinct life stages, a dormant benthic stage and a vegetative pelagic stage.The primary objective of this project was to construct and test a prototype of an autonomous optical sensor for the detection and characterization of HAB-forming algae as they emerge from the sediments.

At A Glance: Georgia Southern University

Georgia Southern at a Glance (2011-2016)

No abstract provided.

Dna Fabrication, A Wake Up Call: The Need To Reevaluate The Admissibility And Reliability Of Dna Evidence, Kristen Bolden

Georgia State University Law Review

In June 2009, Israeli forensic science researchers published a ground breaking study that put credence to the possibility of creating artificial Deoxyribonucleic Acid (DNA) that can fool current forensic testing procedures. The researchers asserted that anyone with the proper equipment and basic understanding of molecular biology could create artificial DNA in virtually unending amounts. Furthermore, the research demonstrates that the current American forensic science system utilized by law enforcement is incapable of distinguishing between artificial and genuine DNA.

National Park Service Nonnative Plant Control In The Indiana Dunes National Lakeshore, Jacob Halpin, Laurie Eberhardt, Laura Thompson

Symposium on Research and Creative Expression (SORCE)

Invasive plants have become a growing threat to plant diversity and hydrology in the Indiana Dunes National Lakeshore. Invasive plants compete with native plants for nutrients and sunlight, and certain invasive species have been known to completely take over certain areas of wetlands, nearly destroying entire ecosystems. The Dunes Lakeshore contains over 1,400 plants species and is one of the top ten most diverse national parks in the United States. The mission statement of the National Park Service is to “preserve for the educational, inspirational, and recreational use of the public certain portions of the Indiana Dunes.” In order …

Improving Ecological Monitoring Of Restoration Sites In Northwest Indiana Through A Glisten-Nirmi Partnership., Danyi Harper, Don Meola

Symposium on Research and Creative Expression (SORCE)

Northwest Indiana is an area of active ecological restoration with 169 documented restoration projects. However, the ability to assess the success of restoration projects is incomplete because monitoring of the progress of these restorations does not exist. NIRMI was created in 2010 to establish a system of evaluating and quantifying plant species in local habitat restoration projects throughout Northwest Indiana. NIRMI uses a standardized approach to collect data that is placed within an open-access database for use by other researchers, restoration groups, and individuals in evaluation of restoration efforts. Data collection uses the CVS-EEP protocol for recording vegetation, a standard …

Baseline Data Analysis Of The Throgren Basin Retrofit, Erin Argyilan, Jennifer Birchfield, Tom Goyne, Nicole Grabos, Caitlin Soley, Jennifer Wunsch

Symposium on Research and Creative Expression (SORCE)

The Thorgren Basin, located in Valparaiso, IN, was created as a component of the stormwater management system for the city. The basin’s primary function is to collect stormwater from two separate regions of the Salt Creek Watershed after large storm events, that is then discharged through a single outlet. In its current state the basin has limited infiltration capabilities due to a lack of vegetation and pervious surfaces. The Save the Dunes Conservation Fund, a local non-profit group, provided a cost share opportunity to naturalize Thorngren basin. The goal of the summer 2011 project was to create a monitoring strategy …

Measure 26: Fear Mongering, Self-Execution & Potential Implications For Birth Control, Jonathan Will

Journal Articles

Depending on what we mean by “fertilization,” there could be impacts on many reproductive choices including birth control, fertility treatments like in vitro fertilization (IVF), and of course, women’s ability to choose to have an abortion. Certain proponents of Measure 26 suggest that even discussing these implications (other than perhaps abortion) amounts to fear mongering. While primarily focusing on birth control, the goal of this essay is to introduce readers to why the concerns regarding these reproductive choices are very real, and how these concerns are further complicated by the issue of whether, if passed, Measure 26 would be deemed …

Out Of The Channel And Into The Swamp: How Family Law Fails In A New Era Of Class Division, June Carbone

Hofstra Law Review

No abstract provided.

Humanized Mouse Models Of Hiv Infection, Paul W. Denton, J. Victor Garcia

Biology Faculty Publications

Because of the limited tropism of HIV, in vivo modeling of this virus has been almost exclusively limited to other lentiviruses such as SIV that reproduce many important characteristics of HIV infection. However, there are significant genetic and biological differences among lentiviruses and some HIV-specific interventions are not effective against other lentiviruses in non-human hosts. For these reasons much emphasis has recently been placed on developing alternative animal models that support HIV replication and recapitulate key aspects of HIV infection and pathogenesis in humans. Humanized mice, CD34+ hematopoietic progenitor cell transplanted immunodeficient mice and in particular mice also implanted with …

Exploring The Population Dynamics Of Wintering Bald Eagles Through Long-Term Data, Julie Beckstead, Alexandra N. Lagasse, Scott R. Robinson

Biology Faculty Scholarship

THE ECOLOGICAL QUESTION

How does a bald eagle population change over time at a winter migratory stopover and which factors influence its abundance?

ECOLOGICAL CONTENT

Bald eagle biology, conservation biology, endangered species, population ecology, and migration ecology (stopover)

WHAT STUDENTS DO

Guided Approach: Students will generate questions about bald eagle numbers influenced by weather and food availability. Students will then use graphing software (JMP or Excel) to compile the data in a graphical form to answer their questions.

Open-ended Approach: Students will generate their own hypotheses of interest from the larger bald eagle data set. This approach is encouraged for …

Exploring The Experiences Of Lesbian Couples Using Fertility Services, Sarah Caitlin Williams

Theses, Dissertations, and Projects

This qualitative study explores the experience of lesbian couples that have used, are using, or attempted to use fertility services since 2003. Thirty-three self identified lesbian women who were in a lesbian relationship at the time of using fertility services participated in the study by completing an online survey consisting of primarily open ended questions. Demographic information such as age and race were asked about both member of the couple.. Findings were analyzed using content analysis. Participant narratives revealed the complexities, challenges, successes, supports relied upon and obstacles encountered when using fertility services; as well as the strength and resiliency …

Sirt1 Modulates Aggregation And Toxicity Through Deacetylation Of The Androgen Receptor In Cell Models Of Sbma, Heather L. Montie, Richard G. Pestell, Diane E. Merry

PCOM Scholarly Works

Posttranslational protein modifications can play a major role in disease pathogenesis; phosphorylation, sumoylation, and acetylation modulate the toxicity of a variety of proteotoxic proteins. The androgen receptor (AR) is substantially modified, in response to hormone binding, by phosphorylation, sumoylation, and acetylation; these modifications might thus contribute to DHT-dependent polyglutamine (polyQ)-expanded AR proteotoxicity in spinal and bulbar muscular atrophy (SBMA). SIRT1, a nuclear protein and deacetylase of the AR, is neuroprotective in many neurodegenerative disease models. Our studies reveal that SIRT1 also offers protection against polyQexpanded AR by deacetylating the AR at lysines 630/632/633. This finding suggested that nuclear AR acetylation …

Implementing A Sheltered Science Course In An Iowa High School, Erin Holt Johnson

All Graduate Theses, Dissertations, and Other Capstone Projects

English Learners (ELs) entering U.S. schools at the high school level face the enormous challenge of acquiring academic literacy as well as secondary-level content in a relatively short period of time. This difficulty is compounded by the fact that a significant number of the ELs entering at the secondary level are students with limited or interrupted formal educations as a result of family migrations, unequal schooling in their home countries, political unrest or even war. In response to this pressing need to teach language and content simultaneously, many school districts are adopting the sheltered instruction (SI) model. This paper will …

Effective Trauma Assessment Tools For Women With Severe Mental Illness, Heather A. Bangu

All Graduate Theses, Dissertations, and Other Capstone Projects

Minnesota Security Hospital (MSH) serves individuals under civil commitment as Mentally Ill and Dangerous by the State of Minnesota. MSH is evaluating its practices to ensure the treatment environment encompasses a recovery oriented, person-centered, and trauma-informed program. Understanding and assessing trauma will assist clinicians in providing patients with the most effective and efficient treatment (Carlson, 1997). Long term negative outcomes exists for individuals with severe mental illness who have experienced trauma including more severe psychiatric symptoms, substance abuse, and homelessness (Mueser, Salyers, Rosenberg, Ford, Fox, & Carty, 2001). The purpose of this Capstone project was to identify and recommend evidence-based …

Perceptions Of Treating Professionals : A Pilot Study Conducted With Employees Of The Edith Nourse Rogers Memorial Veterans Hospital In Bedford, Ma, Alanna Rose Sieck

Theses, Dissertations, and Projects

The objective of this study is to gather information from mental health professionals at the Edith Nourse Rogers Memorial Veterans Hospital in Bedford, Massachusetts about how they perceive patients with Borderline Personality Disorder (BPD). By building on research that has already been conducted, the purpose of this study is to understand if individuals with BPD are stigmatized against by medical professionals. The primary question is whether or not BPD is thought to be synonymous with "difficult" or "hard to treat," leading to less effective treatment. This research will be conducted through an anonymous survey that will be emailed to members …

Fruit And Seed Morphology Of The Fumaria L. Species (Papaveraceae) Of Iran, Fatemeh Ebrahimzadeh Araii, Maryam Keshavarzi, Masoud Sheidaii, Parinaz Ghadam

Turkish Journal of Botany

The macro and micro fruit and seed morphology and surface ornamentations of 21 populations of 6 Fumaria L. species were investigated using stereomicroscope and scanning electron microscopy. These data are shown to support data from the general morphology. The results indicate that the fruit and seed characters of the genus Fumaria are valuable for taxonomic applications and are useful for classification. F. officinalis show a different shape in their fruit. The close relationships are observed for F. parviflora and F. vaillantii. F. indica, as a hybrid between F. asepala and F. parviflora, shows intermediate micro-morphological features.

Macrofungal Diversity Associated With The Scale-Leaf Juniper Trees, Juniperus Excelsa And J. Foetidissima, Distributed In Turkey, Hasan Hüseyi̇n Doğan, Mi̇tko Karadelev, Mustafa Işiloğlu

Turkish Journal of Botany

In this article, an attempt has been made to establish the qualitative composition of macromycetes in the communities of scale-leaf juniper, Juniperus excelsa M.Bieb. and J. foetidissima Willd., distributed in Turkey. A total of 127 species of macrofungi were registered, 2 belonging to Ascomycota and 125 to Basidiomycota. Of those, 69 species were collected in Juniperus excelsa stands, 23 in J. foetidissima stands, and 35 species in both juniper stands. The ecologic status for the fungal species is as follows: 30 lignicolous and 39 terricolous in J. excelsa stands, 19 lignicolous and 4 terricolous in J. foetidissima, and 31 lignicolous …

Ultrastructural Localisation Of Chromium In Ocimum Basilicum, Roya Bishehkolaei, Hamid Fahimi, Sara Saadatmand, Taher Nejadsattari, Mehrdad Lahouti, Forouzan Tabatabaei Yazdi

Turkish Journal of Botany

Ocimum basilicum L. seedlings were exposed to different concentrations of Cr (0-8 mg L^{-1} of Cr^{3+}) to evaluate the cellular localisation of chromium, plant accumulating capacity, and potential cellular defence mechanisms against Cr stress. Dried plant tissues (roots and shoots) were exposed to X-ray microanalysis for element determination (including Cr, Cu, Zn, Co, Ni, and Mo). Results showed that the highest amount of Cr had accumulated in the roots of the plants treated with 8 mg L^{-1} of Cr^{3+}, while less Cr was transported to the shoots. TEM micrographs of Ocimum basilicum root cortex cells exposed to 4, 6, and …

Macrofungi Of Kemaliye District (Erzincan), Hakan Alli

Turkish Journal of Botany

The material of this study comprises macrofungi specimens collected from different localities in Kemaliye district (Erzincan, Turkey) in 2006 and 2007. As a result of field and laboratory studies, 106 taxa under 35 families belonging to the classes Ascomycetes and Basidiomycetes are described: 3 of them, namely Psathyrella panaeoloides (Maire) Arnolds, Galerina stylifera var. stylifera (G.F.Atk.) A.H.Sm. & Singer, and Inocybe amblyspora Kühner, are new records for Turkey.

Strategies For Conserving Forest Genetic Resources In The Face Of Climate Change, John Bradley St.Clair, Glenn Thomas Howe

Turkish Journal of Botany

Conservation of genetic diversity is important for continued evolution of populations to new environments, as well as continued availability of traits of interest in genetic improvement programs. Rapidly changing climates present new threats to the conservation of forest genetic resources. We can no longer assume that in situ reserves will continue to preserve existing genetic diversity. Management of reserves should become more active. In some reserves, existing genetic diversity should be preserved by creating stands that are more resistant to threats using silvicultural treatments such as thinning and prescribed burning. In other reserves, natural selection and adaptation to changed environments …

A Determination Of Air Pollution In Colombo And Kurunegala, Sri Lanka, Using Energy Dispersive X-Ray Fluorescence Spectrometry On Heterodermia Speciosa, Patikiri Arachchilage Don Hasantha Nayana Gunathilaka, Rathnayake Mudiyanselage Nisansala Subodhani Ranundeniya, Mohamed Mujithaba Mohamed Najim, Shirani Seneviratne

Turkish Journal of Botany

Sri Lanka is facing severe environmental problems such as air and water pollution due to rapid industrialisation and urbanisation. Because there have not been many studies on heavy metal pollution in Sri Lanka, the present study attempts to contribute to the literature a determination of metal pollution using indicators found in lichen specimens. Our study utilised energy dispersive X-ray fluorescence spectrometry to determine element concentrations resulting from air pollution in the lichen species Heterodermia speciosa Wulfen. These samples, collected from Colombo and Kurunegala, Sri Lanka, were analysed using the energy dispersive X-ray fluorescence (EDXRF) method in order to determine the …