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2011

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A Case Study Of Problems And Possibilities In The Establishment Of A Guide Training Institute In Uttarakhand, India, Benjamin Schwartz Jan 2011

A Case Study Of Problems And Possibilities In The Establishment Of A Guide Training Institute In Uttarakhand, India, Benjamin Schwartz

Graduate Student Theses, Dissertations, & Professional Papers

This project sought to explore the problems and possibilities experienced during the establishment of a guide training institute in Uttarakhand, India. As originally proposed by the Mountain Shepherds Initiative, a small tourism organization based in Uttarakhand, the aim of the guide training institute was to provide participants with the knowledge and skills needed to gain employment as guides within, and expand the extent of, high quality/low quantity birdwatching tourism within northern Uttarakhand. This project was undertaken in conjunction with the Mountain Shepherds Initiative and the problems and possibilities were identified during a six month stay in the region from May-November, …


Can Sheep Control Leafy Spurge Without Compromising Efforts To Restore Native Plants?, Eva S. Masin Jan 2011

Can Sheep Control Leafy Spurge Without Compromising Efforts To Restore Native Plants?, Eva S. Masin

Graduate Student Theses, Dissertations, & Professional Papers

This thesis includes two studies on the ecological effects of using sheep to control Euphorbia esula (leafy spurge). While sheep can effectively reduce E. esula when used as a long-term management strategy, little is known about their impacts on native plants. The efficacy of sheep grazing for restoration depends both on its potential for controlling undesirable plants and its ability to promote native species that provide key ecosystem goods and services. I investigated the effects of sheep grazing on native plants at both seed and mature-plant stages. To assess impacts on seedling establishment, I measured density of forb and graminoid …


An Examination Of Elementary Physical Education Teachers’ Perceived Self-Efficacy Toward Teaching Children With Orthopedic Impairments In Montana: Do Teachers Feel Competent?, Patricia A. Holman Jan 2011

An Examination Of Elementary Physical Education Teachers’ Perceived Self-Efficacy Toward Teaching Children With Orthopedic Impairments In Montana: Do Teachers Feel Competent?, Patricia A. Holman

Graduate Student Theses, Dissertations, & Professional Papers

An Examination of elementary physical education teachers' perceived self-efficacy toward teaching children with orthopedic impairments in Montana: Do teachers feel competent? Chairperson: Dr. Arthur Miller The purpose of this study was to explore elementary physical educators' self-efficacy beliefs toward teaching children with orthopedic impairments in general physical education class and identify adapted physical education teacher training needs in Montana. The method for this study is based on the Physical Educators' Self-Efficacy Toward Including Students with Disabilities - Autism (PESEISD-A) (Talliaferro et al, 2010) electronic survey instrument and Bandura's (2006) guidelines. A modification of the PESEISD-A instrument was utilized to examine …


Painting For The Eye: Carle Vanloo's Drunken Silenus And The 18th Century French Academy, Anna Buxton Jan 2011

Painting For The Eye: Carle Vanloo's Drunken Silenus And The 18th Century French Academy, Anna Buxton

Graduate Student Theses, Dissertations, & Professional Papers

Buxton, Anna, M.A., Spring 2012 Major Art Painting for the Eye: Carle Vanloo’s Drunken Silenus and the 18th Century French Academy Chairperson: Dr. Valerie Hedquist In 1747, newly appointed Directeur general des Bâtiments du Roi, Charles – François Le Normand de Tournehem organized a concours, or competition, in the French Royal Academy. He hoped to reinvigorate history painting at a time when Rococo themes dominated. With this challenge before him, Tournehem invited ten of the better known academic painters to produce works which challenged the norms of the popular frivolous style. De Tournehem expected edifying subject matter, such as the …


Staphylococcus Aureus Panton-Valentine Leukocidin (Pvl) Alters Human Neutrophil Viability And Function, Shawna Graves Jan 2011

Staphylococcus Aureus Panton-Valentine Leukocidin (Pvl) Alters Human Neutrophil Viability And Function, Shawna Graves

Graduate Student Theses, Dissertations, & Professional Papers

Community-associated methicillin-resistant S. aureus (CA-MRSA) infections are the leading cause of community bacterial infections in the United States. Genes encoding Panton-Valentine leukocidin (PVL) are present in most Staphylococcus aureus strains that cause CA-MRSA infections. Despite an association of PVL with the most abundant CA-MRSA strains, its role in pathogenesis--if any--remains unknown. PVL is a pore-forming toxin with specificity for myeloid cells, including polymorphonuclear leukocytes (PMNs or neutrophils). It is widely assumed that PVL-mediated pore formation in the plasma membrane of PMNs leads ultimately to cytolysis. However, this hypothesis has not been tested and previous studies indicate that levels of PVL …


The Primitive Church, The Primitive Mind, And Methodism In The Eighteenth Century, Kathryn Stasio, Micheal J. Stasio Jan 2011

The Primitive Church, The Primitive Mind, And Methodism In The Eighteenth Century, Kathryn Stasio, Micheal J. Stasio

Religion in the Age of Enlightenment

In The Evangelist of Desire: John Wesley and the Methodists, Henry Abelove reminds his readers that Methodism was part of a larger evangelical movement that began in the 1730s but, while it grew, other sects barely sustained their numbers or disappeared entirely. Citing Frank Baker, Abelove notes that when Wesley died in 1791, Methodists owned 558 preaching houses in the British Isles, and membership totaled 72,476.1 Abelove then chronicles Wesley's ability to lead the Methodist movement, crediting much of its success to the force of Wesley's personality. Yet not all of Wesley's contemporaries found him so charming, as the anti-Methodist …


Healing The Cartesian Split: Understanding And Renewing Pathos In Academic Writing, Travis Washburn Jan 2011

Healing The Cartesian Split: Understanding And Renewing Pathos In Academic Writing, Travis Washburn

Library Research Grants

No abstract provided.


To Lay A Single Stone: A Preliminary Investigation Of James E. Talmage As A Scientist And Museum Professional, Julianna Bratt Jan 2011

To Lay A Single Stone: A Preliminary Investigation Of James E. Talmage As A Scientist And Museum Professional, Julianna Bratt

Library Research Grants

No abstract provided.


Plant Collecting In The Far North: Alaska – British Columbia – Yukon – Northwest Territory, Stanley L. Welsh Jan 2011

Plant Collecting In The Far North: Alaska – British Columbia – Yukon – Northwest Territory, Stanley L. Welsh

Books by Faculty of the Monte L. Bean Life Science Museum

Abstract

Split into three parts, this work contains accounts related to exploration of regions in Alaska and adjacent parts of Canada. Plant specimens were collected and pressed during all three trips. These specimens contributed to the revision of Anderson's Flora of Alaska and adjacent Parts of Canada (Welsh 1974). The Alaska accounts include day-by-day journal entries. A list of new taxa described by S.L. Welsh from these expeditions is included.

Table of Contents

Dedication

Part I. Alaska Expeditions during the years 1965, 1966, and 1968
Alaska Expedition Journal 1965
Alaska Expedition Journal 1966
Alaska Expedition Journal 1968

Part II. British …


Roles Of The 15-Kda Selenoprotein (Sep15) In Redox Homeostasis And Cataract Development Revealed By The Analysis Of Sep 15 Knockout Mice, Marina V. Kasaikina, Dmitri E. Fomenko, Vyacheslav M. Labunskyy, Salil A. Lachke, Wenya Qiu, Juliet A. Moncaster, Jie Zhang, Mark W. Wojnarowicz, Sathish Kumar Natarajan, Mikalai I. Malinouski, Ulrich Schweizer, Petra A. Tsuji, Bradley A. Carlson, Richard L. Maas, Marjorie F. Lou, Lee E. Goldstein, Dolph L. Hatfield, Vadim N. Gladyshev Jan 2011

Roles Of The 15-Kda Selenoprotein (Sep15) In Redox Homeostasis And Cataract Development Revealed By The Analysis Of Sep 15 Knockout Mice, Marina V. Kasaikina, Dmitri E. Fomenko, Vyacheslav M. Labunskyy, Salil A. Lachke, Wenya Qiu, Juliet A. Moncaster, Jie Zhang, Mark W. Wojnarowicz, Sathish Kumar Natarajan, Mikalai I. Malinouski, Ulrich Schweizer, Petra A. Tsuji, Bradley A. Carlson, Richard L. Maas, Marjorie F. Lou, Lee E. Goldstein, Dolph L. Hatfield, Vadim N. Gladyshev

School of Veterinary and Biomedical Sciences: Faculty Publications

The 15-kDa selenoprotein (Sep15) is a thioredoxin-like, endoplasmic reticulum-resident protein involved in the quality control of glycoprotein folding through its interaction with UDP-glucose:glycoprotein glucosyltransferase. Expression of Sep15 is regulated by dietary selenium and the unfolded protein response, but its specific function is not known. In this study, we developed and characterized Sep15 KO mice by targeted removal of exon 2 of the Sep15 gene coding for the cysteinerich UDP-glucose:glycoprotein glucosyltransferase-binding domain. These KO mice synthesized a mutant mRNA, but the shortened protein product could be detected neither in tissues nor in Sep15 KO embryonic fibroblasts. Sep15 KO mice were viable …


Efficient And Stable Expression Of Gfp Through Wheat Streak Mosaic Virus-Based Vectors In Cereal Hosts Using A Range Of Cleavage Sites: Formation Of Dense Fluorescent Aggregates For Sensitive Virus Tracking, Satyanarayana Tatineni, Anthony J. Mcmechan, Gary L. Hein, Roy French Jan 2011

Efficient And Stable Expression Of Gfp Through Wheat Streak Mosaic Virus-Based Vectors In Cereal Hosts Using A Range Of Cleavage Sites: Formation Of Dense Fluorescent Aggregates For Sensitive Virus Tracking, Satyanarayana Tatineni, Anthony J. Mcmechan, Gary L. Hein, Roy French

Department of Plant Pathology: Faculty Publications

A series of Wheat streak mosaic virus (WSMV)-based expression vectors were developed by engineering a cycle 3 GFP (GFP) cistron between P1 and HC-Pro cistrons with several catalytic/cleavage peptides at the Cterminus of GFP. WSMV-GFP vectors with the Foot-and-mouth disease virus 1D/2A or 2A catalytic peptides cleaved GFP from HC-Pro but expressed GFP inefficiently. WSMV-GFP vectors with homologous NIa-Pro heptapeptide cleavage sites did not release GFP from HC-Pro, but efficiently expressed GFP as dense fluorescent aggregates. However, insertion of one or two spacer amino acids on either side of NIb/CP heptapeptide cleavage site or deletion in HC-Pro cistron improved processing …


Simulation Of Electrospun Nanofiber Deposition On Stationary And Moving Substrates, Linhua Liu, Yuris A. Dzenis Jan 2011

Simulation Of Electrospun Nanofiber Deposition On Stationary And Moving Substrates, Linhua Liu, Yuris A. Dzenis

Department of Mechanical and Materials Engineering: Faculty Publications

Electrospinning produces continuous fibers with diameters from single nanometers to microns by jetting polymer solutions in high electric fields. Electrospun non-woven filamentary materials attract rapidly growing interest for broad range of applications. Properties of these materials depend on their nano- and microstructure that is determined in turn by the electric field and nanofiber collector. Despite critical importance, deposition of electrospun fibers on substrates has not yet been extensively studied theoretically and new methods of nanofiber collection continue to be developed mostly empirically. The objective of this Letter was to develop and demonstrate numerical simulation of electrospun nanofiber deposition on moving …


Another Really, Really Big Virus, James L. Van Etten Jan 2011

Another Really, Really Big Virus, James L. Van Etten

Department of Plant Pathology: Faculty Publications

Viruses with genomes larger than 300 kb and up to 1.2 Mb, which encode hundreds of proteins, are being discovered and characterized with increasing frequency. Most, but not all, of these large viruses (often referred to as giruses) infect protists that live in aqueous environments. Bioinformatic analyses of metagenomes of aqueous samples indicate that large DNA viruses are quite common in nature and await discovery. One issue that is perhaps not appreciated by the virology community is that large viruses, even those classified in the same family, can differ significantly in morphology, lifestyle, and gene complement. This brief commentary, which …


Research With Human Subjects, Sarah Fowler-Dixon Jan 2011

Research With Human Subjects, Sarah Fowler-Dixon

Human Research Protection Program (HRPP) Education

No abstract provided.


Historical Timeline, Sarah Fowler-Dixon Jan 2011

Historical Timeline, Sarah Fowler-Dixon

Human Research Protection Program (HRPP) Education

No abstract provided.


Habitat And Landscape Suitability As Indicators Of Bird Abundance In Created And Restored Wetlands, Jordan W. Mora, John N. Mager Iii, Douglas J. Spieles Jan 2011

Habitat And Landscape Suitability As Indicators Of Bird Abundance In Created And Restored Wetlands, Jordan W. Mora, John N. Mager Iii, Douglas J. Spieles

Faculty Publications

No abstract provided.


A Large, Consistent Plasma Proteomics Data Set From Prospectively Collected Breast Cancer Patient And Healthy Volunteer Samples, Catherine P. Riley, Xiang Zhang, Harikrishna Nakshatri, Bryan Schneider, Fred E. Regnier, Jiri Adamec, Charles Buck Jan 2011

A Large, Consistent Plasma Proteomics Data Set From Prospectively Collected Breast Cancer Patient And Healthy Volunteer Samples, Catherine P. Riley, Xiang Zhang, Harikrishna Nakshatri, Bryan Schneider, Fred E. Regnier, Jiri Adamec, Charles Buck

Department of Biochemistry: Faculty Publications

Background: Variability of plasma sample collection and of proteomics technology platforms has been detrimental to generation of large proteomic profile datasets from human biospecimens.

Methods: We carried out a clinical trial-like protocol to standardize collection of plasma from 204 healthy and 216 breast cancer patient volunteers. The breast cancer patients provided follow up samples at 3 month intervals. We generated proteomics profiles from these samples with a stable and reproducible platform for differential proteomics that employs a highly consistent nanofabricated ChipCube™ chromatography system for peptide detection and quantification with fast, single dimension mass spectrometry (LC-MS). Protein identification is achieved with …


Differential Transcription Of Cytochrome P450s And Glutathione S Transferases In Ddt-Susceptible And -Resistant Drosophila Melanogaster Strains In Response To Ddt And Oxidative Stress, Lijie Sun, Brandi Schemerhorn, Amber Jannasch, Kent R. Walters Jr., Jiri Adamec, William M. Muir, Barry R. Pittendrigh Jan 2011

Differential Transcription Of Cytochrome P450s And Glutathione S Transferases In Ddt-Susceptible And -Resistant Drosophila Melanogaster Strains In Response To Ddt And Oxidative Stress, Lijie Sun, Brandi Schemerhorn, Amber Jannasch, Kent R. Walters Jr., Jiri Adamec, William M. Muir, Barry R. Pittendrigh

Department of Biochemistry: Faculty Publications

Metabolic DDT resistance in Drosophila melanogaster has previously been associated with constitutive over-transcription of cytochrome P450s. Increased P450 activity has also been associated with increased oxidative stress. In contrast, over-transcription of glutathione S transferases (GSTs) has been associated with resistance to oxidative stress. However, little is known in regards to the impact of xenobiotics on induction of P450s and GSTs and if there exist differences in inducibility between the pesticide susceptible and resistant strains. Thus, we investigated the transcriptional expression of GSTs and P450s in DDT resistant (Wisconsin) and susceptible (Canton-S) Drosophila strains in response to …


Work As A Manifestation Of Faith In The English Nunnery: Barking Abbey, Essex, Terri Barnes Jan 2011

Work As A Manifestation Of Faith In The English Nunnery: Barking Abbey, Essex, Terri Barnes

Quidditas

This paper discusses various occupations held by nuns in the late-medieval and early-modern English convent, and argues that while the nuns did have extraordinary opportunities for self-management when compared to secular women, nuns carried out those responsibilities in part as extensions and expressions of their faith. This paper looks at offices held by the nuns at Barking Abbey in Essex, from the late Medieval period up to the Abbey’s dissolution in the sixteenth century as a result of the shifting political and religious sands under King Henry VIII. Barking Abbey was a large, wealthy institution that needed capable administration, and …


Motus, Morphology, And Biodiversity Estimation: A Case Study Using Nematodes Of The Suborder Criconematina And A Conserved 18s Dna Barcode, Thomas O. Powers, Timothy Harris, Rebecca Higgins, Peter Mullin, Lisa Sutton, Kirsten Powers Jan 2011

Motus, Morphology, And Biodiversity Estimation: A Case Study Using Nematodes Of The Suborder Criconematina And A Conserved 18s Dna Barcode, Thomas O. Powers, Timothy Harris, Rebecca Higgins, Peter Mullin, Lisa Sutton, Kirsten Powers

Department of Plant Pathology: Faculty Publications

DNA barcodes are increasingly used to provide an estimate of biodiversity for small, cryptic organisms like nematodes. Nucleotide sequences generated by the barcoding process are often grouped, based on similarity, into molecular operational taxonomic units (MOTUs). In order to get a better understanding of the taxonomic resolution of a 3’ 592-bp 18S rDNA barcode, we have analyzed 100 MOTUs generated from 214 specimens in the nematode suborder Criconematina. Previous research has demonstrated that the primer set for this barcode reliably amplifies all nematodes in the Phylum Nematoda. Included among the Criconematina specimens were 25 morphologically described species representing 12 genera. …


Presence Of Fusarium Spp. In Air And Soil Associated With Sorghum Fields, Deanna L. Funnell-Harris, Jeffrey F. Pedersen Jan 2011

Presence Of Fusarium Spp. In Air And Soil Associated With Sorghum Fields, Deanna L. Funnell-Harris, Jeffrey F. Pedersen

Department of Plant Pathology: Faculty Publications

Sorghum grain, valuable for feed, food, and bioenergy, can be colonized by several Fusarium spp.; therefore, it was of interest to identify possible sources of conidia. Analysis of air and soil samples provided evidence for the presence of propagules from Fusarium genotypes that may cause grain infections. Soil population estimates of members of the Gibberella fujikuroi species complex, that includes sorghum pathogens and other Fusarium spp., suggested that adequate inoculum for systemic infections was present. Conidia in air samples within two sorghum fields were collected by passive trapping for 2 years. Subsampled Fusarium isolates indicated that numbers of G. fujikuroi …


First Report Of Goss's Bacterial Wilt And Leaf Blight (Clavibacter Michiganensis Subsp. Nebraskensis) Of Corn In Texas, K. A. Korus, A. D. Timmerman, R. D. French-Monar, T. A. Jackson Jan 2011

First Report Of Goss's Bacterial Wilt And Leaf Blight (Clavibacter Michiganensis Subsp. Nebraskensis) Of Corn In Texas, K. A. Korus, A. D. Timmerman, R. D. French-Monar, T. A. Jackson

Department of Plant Pathology: Faculty Publications

In September 2009, the University of Nebraska–Lincoln Plant and Pest Diagnostic Clinic received leaf samples of hybrid corn (Zea mays L.) displaying long, necrotic lesions with wavy margins. The lesions had discontinuous water-soaked spots that are indicative of Goss's bacterial wilt and leaf blight. The symptomatic leaves were submitted from Dallam County, located in the Texas Panhandle (northwest Texas). According to the USDA Farm Service Agency and the National Agricultural Statistics Service, in 2009 Dallam County had 54,025 ha planted to corn. This is approximately 19% of the total corn planted in the 26 counties in the Texas Panhandle …


Effects Of Integrating Cultivar Resistance And Fungicide Application On Fusarium Head Blight And Deoxynivalenol In Winter Wheat, Stephen N. Wegulo, William W. Bockus, John Hernandez Nopsa, Erick D. De Wolf, Kent M. Eskridge, Kamaranga H. S. Peiris, Floyd E. Dowell Jan 2011

Effects Of Integrating Cultivar Resistance And Fungicide Application On Fusarium Head Blight And Deoxynivalenol In Winter Wheat, Stephen N. Wegulo, William W. Bockus, John Hernandez Nopsa, Erick D. De Wolf, Kent M. Eskridge, Kamaranga H. S. Peiris, Floyd E. Dowell

Department of Plant Pathology: Faculty Publications

Fusarium head blight (FHB) or scab, incited by Fusarium graminearum, can cause significant economic losses in small grain production. Five field experiments were conducted from 2007 to 2009 to determine the effects on FHB and the associated mycotoxin deoxynivalenol (DON) of integrating winter wheat cultivar resistance and fungicide application. Other variables measured were yield and the percentage of Fusarium-damaged kernels (FDK). The fungicides prothioconazole + tebuconazole (formulated as Prosaro 421 SC) were applied at the rate of 0.475 liters/ha, or not applied, to three cultivars (experiments 1 to 3) or six cultivars (experiments 4 and 5) differing in their …


Characterization Of Three-Dimensional Spatial Aggregation And Association Patterns Of Brown Rot Symptoms Within Intensively Mapped Sour Cherry Trees, Sydney E. Everhart, Ashley Askew, Lynne Seymour, Imre J. Holb, Harald Scherm Jan 2011

Characterization Of Three-Dimensional Spatial Aggregation And Association Patterns Of Brown Rot Symptoms Within Intensively Mapped Sour Cherry Trees, Sydney E. Everhart, Ashley Askew, Lynne Seymour, Imre J. Holb, Harald Scherm

Department of Plant Pathology: Faculty Publications

Characterization of spatial patterns of plant disease can provide insights into important epidemiological processes such as sources of inoculum, mechanisms of dissemination, and reproductive strategies of the pathogen population. While two-dimensional patterns of disease (among plants within fields) have been studied extensively, there is limited information on three-dimensional patterns within individual plant canopies. Reported here are the detailed mapping of different symptom types of brown rot (caused by Monilinia laxa) in individual sour cherry tree (Prunus cerasus) canopies, and the application of spatial statistics to the resulting data points to de-termine patterns of symptom aggregation and association. …


Human Sanitary Wastes And Waste Treatment In New York City, David J. Tonjes, Christine O'Connell, Omkar Aphale, R. Lawrence Swanson Jan 2011

Human Sanitary Wastes And Waste Treatment In New York City, David J. Tonjes, Christine O'Connell, Omkar Aphale, R. Lawrence Swanson

Technology & Society Faculty Publications

Henry Hudson first sailed toNew Yorkharbor 400 years ago. Since then,New York Cityhas both affected and been affected by water quality in greaterNew YorkHarbor. In this paper, we focus on sewers, sewerage, and sewage treatment inManhattanand their effects on theHudson River. It is clear that feedbacks among drinking water quality and quantity, population, public perceptions, regulations, and estuarine water quality exist, although their strength and character have varied over time. Early land uses damaged local water supplies found on ManhattanIsland. New Yorkthen began to exploit the large fresh water resources available to its north, which helped the City to expand …


Social Media At Academia's Periphery: Studying Multilingual Developmental Writers' Facebook Composing Strategies, Kevin Eric Depew Jan 2011

Social Media At Academia's Periphery: Studying Multilingual Developmental Writers' Facebook Composing Strategies, Kevin Eric Depew

English Faculty Publications

This article focuses on the writing strategies second-language students use to compose on social media sites. These alternative and unconventional sites for learning provide language learners opportunities to acquire language by using multiple modalities to respond to various rhetorical situations. In comparison to these sites, academic writing contexts, particularly the developmental-writing course, impose monolingual norms and deficient identities on students. Where these courses articulate these language learners as possessing inadequate skills to perform well in mainstream writing courses, the students' social-media compositions demonstrate that these students have the potential to respond to communicative situations in rhetorically complex ways. This study …


Altitudinal Variation Of Freeze Tolerance In The Pacific Chorus Frog, Pseudacris Regilla, Sara Healas Jan 2011

Altitudinal Variation Of Freeze Tolerance In The Pacific Chorus Frog, Pseudacris Regilla, Sara Healas

Undergraduate Honors Theses

This study compares the physiological responses to freezing of Pacific Chorus frogs (Pseudacris regilla) from low-elevation and high-elevation sites. During the winter months, Pacific Chorus frogs have the ability to freeze solid and revive upon thawing. They survive freezing because they store massive amounts of glycogen that they convert into glucose once freezing starts. Glucose is use (1) to protect the cells during freezing and (2) to support general metabolism through the entire winter. The hypothesis is that the frogs collected at the high-elevation site will have more glucose stored as glycogen because these frogs have to survive …


Investigating The Effects Of The Plasticizers Bisphenol A And Di (2-Ethylhexyl) Phthalate On Dopaminergic Neurons In A C. Elegans Parkinson's Disease, Amanda Valera Jan 2011

Investigating The Effects Of The Plasticizers Bisphenol A And Di (2-Ethylhexyl) Phthalate On Dopaminergic Neurons In A C. Elegans Parkinson's Disease, Amanda Valera

Undergraduate Honors Theses

Parkinson's disease (PD) is a neurodegenerative disorder characterized by loss of dopamine (DA) containing neurons in the substantia nigra of the brain. Though the cellular pathways that lead to PD are varied and not well understood, elevated levels of reactive oxygen species (ROS) and inhibition of the mitochondrial electron transport chain enzyme complex I have been associated with PD pathogenesis. Environmental factors such as the plasticizers bisphenol A (BPA) and di(2-ethylhexyl) phthalate (DEHP) may also be involved in PD pathogenesis. In this research, three strains of the nematode Caenorhabditis elegans (C. elegans), a wild-type N2 strain, a ROS-sensitive nnt …


Fact Book 2011-12, Western Michigan University Jan 2011

Fact Book 2011-12, Western Michigan University

Western Michigan University Fact Books

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Faculty Senate Yearbook, 2011-12, Wmu Faculty Senate Jan 2011

Faculty Senate Yearbook, 2011-12, Wmu Faculty Senate

WMU Faculty Senate Yearbooks

No abstract provided.