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2011

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Beneath The Surface Of Global Change: Impacts Of Climate Change On Groundwater, Timothy R. Green, Makoto Taniguchi, Henk Kooi, Jason J. Gurdak, Diana M. Allen, Kevin M. Hiscock, Holger Treidel, Alice Aureli Jan 2011

Beneath The Surface Of Global Change: Impacts Of Climate Change On Groundwater, Timothy R. Green, Makoto Taniguchi, Henk Kooi, Jason J. Gurdak, Diana M. Allen, Kevin M. Hiscock, Holger Treidel, Alice Aureli

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Global change encompasses changes in the characteristics of inter-related climate variables in space and time, and derived changes in terrestrial processes, including human activities that affect the environment. As such, projected global change includes groundwater systems. Here, groundwater is defined as all subsurface water including soil water, deeper vadose zone water, and unconfined and confined aquifer waters. Potential effects of climate change combined with land and water management on surface waters have been studied in some detail. Equivalent studies of groundwater systems have lagged behind these advances, but research and broader interest in projected climate effects on groundwater have been …


Landform, Soil, And Plant Relationships To Nitrate Accumulation, Central Nevada, W.D. Nettleton, F.F. Peterson Jan 2011

Landform, Soil, And Plant Relationships To Nitrate Accumulation, Central Nevada, W.D. Nettleton, F.F. Peterson

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Nitrate (NO3 −1) accumulates in Haplocambids and Torrifluvents in inset fan and fan skirt positions in central Nevada. The soils store as much as 17,600 kg of NO3 −1 N ha−1 within the upper 208 cm. This paper provides an explanation. These Holocene soils receive NO3 −1 N from mineralization of organic matter and other NO3 −1 N sources including snowmelt. The NO3 −1 is delivered to soils in the first part of snowmelt in run-off from the higher surfaces. The last part of the melt and the run-off, when sufficient, serve to move the …


Functional Connectivity For Configural And Featural Face Processing In The Broad Autism Phenotype, Jonathan Darrell Clark Jan 2011

Functional Connectivity For Configural And Featural Face Processing In The Broad Autism Phenotype, Jonathan Darrell Clark

University of Kentucky Doctoral Dissertations

During normal development, face processing involves a gradual shift from a featurally oriented style to a mature configural style by adolescence. This shift may coincide with increased right hemispheric dominance for faces supporting configural processing. Previous studies suggest that individuals diagnosed with ASD continue to process faces using individual parts and features into adulthood. This continued bias may be due to deficits in configural processing abilities. The current study investigated measures of functional connectivity during featural and configural processing of faces in broad autism phenotype sibling (ASD-sibs) children compared to age, sex, and handedness matched normal developing (ND) controls and …


Animal Law—Cultivating Compassionate Law: Unlocking The Laboratory Door And Shining Light On The Inadequacies & Contradictions Of The Animal Welfare Act, Karina L. Schrengohst Jan 2011

Animal Law—Cultivating Compassionate Law: Unlocking The Laboratory Door And Shining Light On The Inadequacies & Contradictions Of The Animal Welfare Act, Karina L. Schrengohst

Western New England Law Review

This Note discusses the social movement to confer legal protections and rights on animals in an effort to end their suffering in laboratories from invasive research. It argues that primates, in particular, should be retired to sanctuaries where they will be guaranteed a right to dignity and a life free from confinement and torture. Part I of this Note reveals a glimpse of the range of research conducted on primates, and offers examples of primates’ intellectual abilities and emotional capacities. Part II takes account of competing theory—animal welfare theory, animal rights theory, and feminist animal care theory—and traces the evolution …


An Investigation Into Use Of The Freshwater Gastropod Viviparus As A Recorder Of Past Climatic Change, Melanie Bugler Jan 2011

An Investigation Into Use Of The Freshwater Gastropod Viviparus As A Recorder Of Past Climatic Change, Melanie Bugler

Other Faculty of Science and Engineering Theses

Through isotopic analysis of Viviparus lentus (V. lentus) a high resolution record of stepwise changes in δ18O and δ13C across the Eocene / Oligocene transition and Oi-1 glacial maximum has been produced for the continental Solent Group strata, Isle of Wight (UK). Comparison of this V. lentus δ18Ocarb. record with high resolution marine δ18Ocarb. records shows that similar isotopic shifts exist in the near coastal continental and marine realms. In order to calculate palaeotemperatures from this new continental record an investigation into the biology of modern Viviparus and its effect on the isotopic composition of its shell carbonate was undertaken. …


Water Law In The United States And Brazil--Climate Change & Two Approaches To Emerging Water Poverty, David N. Cassuto, Romulo S.R. Sampaio Jan 2011

Water Law In The United States And Brazil--Climate Change & Two Approaches To Emerging Water Poverty, David N. Cassuto, Romulo S.R. Sampaio

Elisabeth Haub School of Law Faculty Publications

This article examines two of the major water legal regimes in the Americas-that of Brazil and the United States. Both countries have extensive wet and dry regions and both hydro-regimes face a significant threat from global warming. Brazil, for instance, is home to between eight and fifteen percent of the world's fresh water, and its fast-growing economy and population present major challenges in management and allocation. The U.S. also faces major water allocation problems resulting from past settlement policies; unsustainable reclamation projects; and also fast-growing domestic, industrial and agricultural demand. In the United States, water has traditionally been perceived as …


Unsex Cedaw, Or What's Wrong With Women's Rights, Darren Rosenblum Jan 2011

Unsex Cedaw, Or What's Wrong With Women's Rights, Darren Rosenblum

Elisabeth Haub School of Law Faculty Publications

Part I discusses why CEDAW continues to be relevant as the primary source of international law on sex discrimination. Until the advent of the Convention on the Rights of the Child (CRC), CEDAW was the most widely-subscribed international treaty. Some of the draft language of CEDAW reflects the tension between category and identity and how "women" won the debate. Part II contrasts CEDAW with the Convention for the Elimination of Racial Discrimination (CERD). It points to the identitarian focus of CEDAW as a core reason for its failures. Had CEDAW reflected a category focus, as CERD did, it would more …


Role Of Leptin And Its Receptors In The Pathogenesis Of Thyroid Cancer, Shahabuddin, Azhar Hussain, Abdul K Siraj, Omar S Khan, Prashant P Bavi, Khawla S Al-Kuraya Jan 2011

Role Of Leptin And Its Receptors In The Pathogenesis Of Thyroid Cancer, Shahabuddin, Azhar Hussain, Abdul K Siraj, Omar S Khan, Prashant P Bavi, Khawla S Al-Kuraya

Centre for Regenerative Medicine & Stem Cell Research

Leptin is a multifunctional adipose-derived cytokines that play a critical role in bodyweight homeostasis and energy balance. Recently, leptin and leptin receptor dysreulation have been reported in variety of malignant cells including thyroid. Leptin modulates growth and proliferation of cancer cells via activation of various growth and survival signaling pathways including JAK/STAT, PI3-kinase/AKT and/or Map kinases. In this review, current understanding of leptin's role in the pathogenesis of thyroid cancer has been described.


Resveratrol Suppresses Constitutive Activation Of Akt Via Generation Of Ros And Induces Apoptosis In Diffuse Large B Cell Lymphoma Cell Lines, Azhar Hussain, Shahabuddin, Rong Bu, Omar S. Khan, Saeeda O. Ahmed, Maqbool Ahmed, Khawla S. Al-Kuraya Jan 2011

Resveratrol Suppresses Constitutive Activation Of Akt Via Generation Of Ros And Induces Apoptosis In Diffuse Large B Cell Lymphoma Cell Lines, Azhar Hussain, Shahabuddin, Rong Bu, Omar S. Khan, Saeeda O. Ahmed, Maqbool Ahmed, Khawla S. Al-Kuraya

Centre for Regenerative Medicine & Stem Cell Research

Background: We have recently shown that deregulation PI3-kinase/AKT survival pathway plays an important role in pathogenesis of diffuse large B cell lymphoma (DLBCL). In an attempt to identify newer therapeutic agents, we investigated the role of Resveratrol (trans-3,4′, 5-trihydroxystilbene), a naturally occurring polyphenolic compound on a panel of diffuse large B-cell lymphoma (DLBCL) cells in causing inhibition of cell viability and inducing apoptosis.
Methodology/Principal Findings: We investigated the action of Resveratrol on DLBCL cells and found that Resveratrol inhibited cell viability and induced apoptosis by inhibition of constitutively activated AKT and its downstream targets via generation of reactive oxygen species …


Assisted Migration: A Viable Conservation Strategy To Preserve The Biodiversity Of Threatened Island Nations?, Jessica A. Wentz Jan 2011

Assisted Migration: A Viable Conservation Strategy To Preserve The Biodiversity Of Threatened Island Nations?, Jessica A. Wentz

Sabin Center for Climate Change Law

Anthropogenic climate change poses a substantial threat to biodiversity. The IPCC estimates that 20-30% of species will face an increased risk of extinction if the average global temperature rises more than 1.5 to 2.5 degrees Celsius. Additional scientific studies indicate that 15-37% of species may become extinct by 2050 due to global warming, based on current emissions trajectories. Domestic and international strategies to manage this threat have traditionally focused on conservation and mitigation. In the last few years, however, policy makers have recognized that near-term climate impacts are inevitable and thus adaptation strategies are required to protect both humans and …


Ethnic Politics And Conflicts In Nigeria: Theoretical Perspective, Joseph C. Ebegbulem Jan 2011

Ethnic Politics And Conflicts In Nigeria: Theoretical Perspective, Joseph C. Ebegbulem

Khazar Journal of Humanities and Social Sciences

According to Okwudiba Nnoli (2007) “Ethnicity is a social phenomenon associated with contact among ethnic groups that exist within the same political system. it is characterized by cultural prejudice and social discrimination.” Nigeria is confronted with problems which have resulted in the dramatic upsurge in ethnic conflicts which is a bye-product of ethnic nationalism and political demands based on ethnicity. From the colonial period to the return to civil politics since 1999 Nigeria has witnessed the resurgence of political demands along ethnic lines. The liberalization of the polity and the expansion of the political space appear to have provided additional …


Domestic Mitigation Of Black Carbon From Diesel Emissions, Hannah Chang Jan 2011

Domestic Mitigation Of Black Carbon From Diesel Emissions, Hannah Chang

Sabin Center for Climate Change Law

Black carbon, a component of soot and particulate matter, competes closely with methane as the largest anthropogenic contributor to global warming after carbon dioxide. Regulation of black carbon has been identified as an affordable, politically feasible, fast-action means to mitigate the warming temperatures caused by climate change. With an emphasis on domestic mitigation, this Article examines how emissions are controlled under the CAA and what EPA, states, and municipalities can do to mitigate black carbon emissions further.


Effects Of Vocal Toning And Bio Acoustics Assessment On Pain And Bio Acoustics Vocal Profile, Crista Marie Orefice Jan 2011

Effects Of Vocal Toning And Bio Acoustics Assessment On Pain And Bio Acoustics Vocal Profile, Crista Marie Orefice

Theses, Dissertations and Culminating Projects

The objective of this research study was to investigate the effects of vocal toning interventions informed by a BioAcoustics assessment tool on the perceived pain and the vocal profile in a participant diagnosed with fibromyalgia. The study employed a single case study design. The participant (N=l) was a woman diagnosed with fibromyalgia, who underwent a series of ten 25-minute music therapy treatments of vocal toning, twice a week, for five weeks. Vocal profile was recorded and measured with the BioAcoustics nano Voice program for each session, pre- and post-treatment. Perceived pain was measured using the Brief Pain Inventory (BPI) questionnaire …


'Race', Nation And Belonging In Ireland, Jonathan Mitchell Jan 2011

'Race', Nation And Belonging In Ireland, Jonathan Mitchell

Irish Journal of Applied Social Studies

Despite consistent efforts to counteract those attitudes and practices that give rise to it, most putatively modern Western nations continue to experience the concrete effects of racial discrimination. This essay argues that nationality is all too easily conflated with ‘race’ or ethnicity, such that a seeming essence or givenness is manifested amongst all those within a particular geographic boundary. It is suggested that on the contrary, there is nothing natural about nationality as commonly understood; this being so, it must be continually shored up and reconstituted through social, linguistic and material practices. For modern nations in the West, this has …


Technology Assessment 2.0: Revamping Our Approach To Emerging Technologies, Albert C. Lin Jan 2011

Technology Assessment 2.0: Revamping Our Approach To Emerging Technologies, Albert C. Lin

Brooklyn Law Review

No abstract provided.


Divine Command Moral Ontology, Kiefer Owens Jan 2011

Divine Command Moral Ontology, Kiefer Owens

A with Honors Projects

No abstract provided.


Reflections On Science, Ken Smith Jan 2011

Reflections On Science, Ken Smith

A with Honors Projects

No abstract provided.


Biology Of Consciousness, G. Edelman, J. Gally, B. Baars Jan 2011

Biology Of Consciousness, G. Edelman, J. Gally, B. Baars

CCRG Papers

No abstract provided.


Modeling Medical Diagnosis Using A Comprehensive Cognitive Architecture, S. Strain, S. Franklin Jan 2011

Modeling Medical Diagnosis Using A Comprehensive Cognitive Architecture, S. Strain, S. Franklin

CCRG Papers

No abstract provided.


The Use Of Omega-3 Fatty Acids In Mental Illness, Jessica L. Gören, T. Tewksbury Jan 2011

The Use Of Omega-3 Fatty Acids In Mental Illness, Jessica L. Gören, T. Tewksbury

Pharmacy Practice and Clinical Research Faculty Publications

Purpose: This article will summarize the current evidence on the effects of omega-3 fatty acids on prevention and treatment of mental illness. Background: Omega-3 fatty acids are involved in many physiologic processes. Since they cannot be made de novo in the body, they are considered essential nutrients. As the Western diet evolved, dietary intake of fatty acids has shifted to increased omega-6 fatty acids and decreased omega-3 fatty acids intake. These changes have been correlated with numerous differences in prevalence and course of mental illnesses. Methods: A MEDLINE search from 1966 to December 2010 was completed to …


The Pulmonologist's Role In Caring For Pregnant Women With Regard To The Reproductive Risks Of Diagnostic Radiological Studies Or Radiation Therapy, Robert L. Brent Dr. Jan 2011

The Pulmonologist's Role In Caring For Pregnant Women With Regard To The Reproductive Risks Of Diagnostic Radiological Studies Or Radiation Therapy, Robert L. Brent Dr.

The Selected Works of Robert Brent

None


The Pulmonologist's Role In Caring For Pregnant Women With Regard To The Reproductive Risks Of Diagnostic Radiological Studies Or Radiation Therapy, Robert L. Brent Dr. Jan 2011

The Pulmonologist's Role In Caring For Pregnant Women With Regard To The Reproductive Risks Of Diagnostic Radiological Studies Or Radiation Therapy, Robert L. Brent Dr.

The Selected Works of Robert Brent

No abstract


The Role Of The Pediatrican In The Effort To Prevent Congenital Malformations, Robert L. Brent Dr. Jan 2011

The Role Of The Pediatrican In The Effort To Prevent Congenital Malformations, Robert L. Brent Dr.

The Selected Works of Robert Brent

No


Evaluation Of Reproductive And Developmental Risks Of Caffeine, Robert L. Brent Dr. Jan 2011

Evaluation Of Reproductive And Developmental Risks Of Caffeine, Robert L. Brent Dr.

The Selected Works of Robert Brent

No abstract provided.


The Professonal Responsibility Model Of Obstetrical Ethics: Avoiding The Perils Of Clashing Rights, Robert L. Brent, Frank A. Chervenak, Md, Laurence B. Mccullough, Phd Jan 2011

The Professonal Responsibility Model Of Obstetrical Ethics: Avoiding The Perils Of Clashing Rights, Robert L. Brent, Frank A. Chervenak, Md, Laurence B. Mccullough, Phd

The Selected Works of Robert Brent

Obstetric ethics is sometimes represented by polarized views. One extreme asserts the rights of the fetus as the overwhelming ethical consideration. Both assertions are overly simplistic. Such oversimplification is called reductionism. This article explains the fallacy of rights-based reductionism and 2 models of obstetric ethics based on it and explains why the fetal rights reductionism model and the pregnant woman's rights reductionism model result in conceptual and clinical failure and therefore should be abandoned. The article argues for the professional responsibility model of obstetric ethics, which emphasizes the importance of medical science and compassionate clinical care of both the pregnant …


Tissue-Specific Regulation Of Mouse Microrna Genes In Endoderm-Derived Tissues., Yan Gao, Jonathan Schug, Lindsay B Mckenna, John Le Lay, Klaus H Kaestner, Linda E Greenbaum Jan 2011

Tissue-Specific Regulation Of Mouse Microrna Genes In Endoderm-Derived Tissues., Yan Gao, Jonathan Schug, Lindsay B Mckenna, John Le Lay, Klaus H Kaestner, Linda E Greenbaum

Department of Cancer Biology Faculty Papers

MicroRNAs fine-tune the activity of hundreds of protein-coding genes. The identification of tissue-specific microRNAs and their promoters has been constrained by the limited sensitivity of prior microRNA quantification methods. Here, we determine the entire microRNAome of three endoderm-derived tissues, liver, jejunum and pancreas, using ultra-high throughput sequencing. Although many microRNA genes are expressed at comparable levels, 162 microRNAs exhibited striking tissue-specificity. After mapping the putative promoters for these microRNA genes using H3K4me3 histone occupancy, we analyzed the regulatory modules of 63 microRNAs differentially expressed between liver and jejunum or pancreas. We determined that the same transcriptional regulatory mechanisms govern tissue-specific …


Investigating The Role Of Calcineurin In Axon Growth And Development Of Retinal Neurons, Jesus Iniguez Jan 2011

Investigating The Role Of Calcineurin In Axon Growth And Development Of Retinal Neurons, Jesus Iniguez

Undergraduate Honors Theses

This research project entails the characterization of Calcineurin (CaN) in neuron development. CaN is an intracellular protein that has been implicated in different systems as a mediator between cells and their surroundings to promote normal, healthy function (Lee & Park; 2006). Receptors on the surface of cells are known to stimulate intracellular changes, CaN is thought to mediate some of these changes, including during neurodevelopment. As a neuron develops, it extends a process (axon) in search of a specific target with which to form a synapse. Initial embryonic axon growth is directly related to axon growth and regeneration in adults. …


A Survey Of The Chemical Content And Medicinal Activity Of Shrub-Steppe Plants Of The Pacific Northwest, Aaron M. John Jan 2011

A Survey Of The Chemical Content And Medicinal Activity Of Shrub-Steppe Plants Of The Pacific Northwest, Aaron M. John

Undergraduate Honors Theses

A need for new modes of antibiotic therapy has resulted from the increasing incidence of bacterial resistance to drugs. One approach to this problem involves the search for plant compounds that may help to overcome multi-drug resistance. Many plant genera have been utilized in Native American traditional medicine for their beneficial properties. Such plants include the shrub-steppe genera, Eriogonun and Collomia, which have been used as cold remedies, pain relievers, and for antibiotic-related uses. Limited chemical studies of these genera have revealed medicinally useful compounds such as flavonoids and terpenoids, and further research may result in the identification of …


Beyond The Chemistry Web, Bob Buchanan Jan 2011

Beyond The Chemistry Web, Bob Buchanan

Sci-Tech News

No abstract provided.


Evolution And Personal Religious Belief: Christian University Biology-Related Majors’ Search For Reconciliation, Mark Winslow, John Staver, Lawrence C. Scharmann Jan 2011

Evolution And Personal Religious Belief: Christian University Biology-Related Majors’ Search For Reconciliation, Mark Winslow, John Staver, Lawrence C. Scharmann

Department of Teaching, Learning, and Teacher Education: Faculty Publications

The goal of this study was to explore Christian biology-related majors’ perceptions of conflicts between evolution and their religious beliefs. This naturalistic study utilized a case study design of 15 undergraduate biology-related majors at or recent biology-related graduates from a mid-western Christian university. The broad sources of data were interviews, course documents, and observations. Outcomes indicate that most participants were raised to believe in creationism, but came to accept evolution through evaluating evidence for evolution, negotiating the literalness of Genesis, recognizing evolution as a non-salvation issue, and observing professors as Christian role models who accept evolution. This study lends heuristic …