Digital Commons Network^™

Effect Of Aging On Cellular Mechanotransduction, Miaozong Wu, Jacqueline Fannin, Kevin M. Rice, Bin Wang, Eric R. Blough

MIIR Faculty Research

Aging is becoming a critical heath care issue and a burgeoning economic burden on society. Mechanotransduction is the ability of the cell to sense, process, and respond to mechanical stimuli and is an important regulator of physiologic function that has been found to play a role in regulating gene expression, protein synthesis, cell differentiation, tissue growth, and most recently, the pathophysiology of disease. Here we will review some of the recent findings of this field and attempt, where possible, to present changes in mechanotransduction that are associated with the aging process in several selected physiological systems, including musculoskeletal, cardiovascular, neuronal, …

Academic Gateway, Winter 2011, San Jose State University Library

Library Gateway

No abstract provided.

Mothers And Infants In The Prehistoric Santa Clara Valley: What Stable Isotopes Tell Us About Ancestral Ohlone Weaning Practices, Alan M. Leventhal, Karen S. Gardner, Rosemary Cambra, Eric J. Bartelink, Antoinette Martinez

Faculty Publications, Anthropology

Breast-feeding and weaning are a part of childhood in all human populations, but the exact timing of these milestones varies between groups. As infants incorporate the nutrients from breast milk into their growing bones, chemical evidence is captured in the form of higher stable nitrogen (δ15N) isotope values. This study interprets δ15N values in the bone collagen of children (n = 24) buried at the Yukisma Mound (CA-SCL-38), in Santa Clara County, California. Radiocarbon dates for this site span 2200-250 B.P., but primarily fall during the Late period (740-230 B.P.). In the one probable mother-infant pair available for study, a …

Innovate Magazine / Annual Review 2010-2011, San Jose State University

Innovate Magazine (School of Information)

No abstract provided.

"Atlas Shrugged" And Third-Wave Feminism: An Unlikely Alliance, Paul Mcmahan

MA in English Theses

Ayn Rand and her work are often ignored by feminist critics because of Rand's personal life, her views on sex, and her vehement rejections of collectivism. Feminism has moved through overlapping waves known as first, second, and third-wave feminism. Throughout its life feminism has been marked by two strands: relational and individual. The strand of individual feminism has been more prevalent in Anglo-American feminism while relational feminism has been more predominant in European feminism. Atlas Shrugged was published six years prior to Betty Friedan's The Feminine Mystique , a text generally agreed upon as the starting point for second-wave feminism. …

Utah State Magazine, Winter 2011, Utah State University

Utah State Magazine

No abstract provided.

Conditional Posterior Cramer-Rao Lower Bound And Distributed Target Tracking In Sensor Networks, Long Zuo

Electrical Engineering and Computer Science - Dissertations

Sequential Bayesian estimation is the process of recursively estimating the state of a dynamical system observed in the presence of noise. Posterior Cramer-Rao lower bound (PCRLB) sets a performance limit onany Bayesian estimator for the given dynamical system. The PCRLBdoes not fully utilize the existing measurement information to give anindication of the mean squared error (MSE) of the estimator in the future. In many practical applications, we are more concerned with the value of the bound in the future than in the past. PCRLB is an offline bound, because it averages out the very useful measurement information, which makes it …

The Consequence Of Anthropogenic Disturbance On Communication And The Operation Of Sexual Selection In The Eastern Bluebird (Sialia Sialis), Ellen Michale Wisner

Biology - Dissertations

Signals that are efficiently transmitted and easily detected in their signaling environment are favored by natural selection. Anthropogenic disturbance can rapidly alter the signaling environment, and recent studies have shown that acoustic and visual signals change in response to these altered habitats. Although these studies provide important insight into the effects of urbanization on animal signals and have served as experiments testing the role of the environment in shaping signal design, several key aspects of how signal design can be influenced by environmental changes remain unclear.

Previous studies have focused on signals used between adults, such as those used in …

The Maintenance Of Male Color Polymorphism In Poecilia Parae, Jorge L. Hurtado-Gonzales

Biology - Dissertations

Genetic color polymorphisms are common in nature, and a major challenge for evolutionary biologists has been to understand how they are maintained despite the effects of directional selection. Recent studies suggest that frequency-dependent selection may explain the persistence of intraspecific variation in color. However, it remains to be determined whether frequency-dependent selection is the most predominant (or perhaps the only) mechanism to maintain such genetically-based polymorphisms. Using a South American fish, Poecilia parae, my dissertation aims to elucidate the relative roles of natural and sexual selection in the maintenance of polymorphisms in natural populations. Poecilia parae males exhibit five distinct, …

Culture, Dissent, And The State: The Example Of Commonwealth African Marriage Law, Johanna E. Bond

Scholarly Articles

This is an explosive time for those seeking to define the meaning and parameters of marriage. The subject has generated heated debate worldwide. In June 2010, the European Court of Human Rights declined to extend marriage rights to a gay Austrian couple, but the Court carefully laid the foundation for the recognition of such rights when a European consensus on the issue emerges. In July 2010, Argentina extended to same-sex couples the right to marry, joining nine other countries that legally recognize same-sex couples' right to marry. In August 2010, a United States district judge struck down a California ban …

Taking Away An Employer's Free Pass: Making The Case For A More Sophisticated Sex-Plus Analysis In Employment Discrimination Cases, Heather M. Kolinsky

Scholarly Articles

In this article the author advocates for a broader interpretation of sex-plus theory to encompass the concept of mother as a gender identified category.

Department Of Chemistry And Biochemistry, 15th Annual Departmental Symposium And Poster Session In Conjunction With The Petersheim Academic Exposition, Department Of Chemistry And Biochemistry, Seton Hall University

Chemistry and Biochemistry Student Work

No abstract provided.

Modeling The Effects Of A Simple Immune System And Immunodeficiency On The Dynamics Of Conjointly Growing Tumor And Normal Cells, Mitra Shojania-Feizabadi, Tarynn M. Witten

Physics Publications

In this paper, we develop a theoretical contribution towards the understanding of the complex behavior of conjoint tumor-normal cell growth under the influence of immuno-chemotheraputic agents under simple immune system response. In particular, we consider a core model for the interaction of tumor cells with the surrounding normal cells. We then add the effects of a simple immune system, and both immune-suppression factors and immuno-chemotherapeutic agents as well. Through a series of numerical simulations, we illustrate that the interdependency of tumor-normal cells, together with choice of drug and the nature of the immunodeficiency, leads to a variety of interesting patterns …

Old Broken Crayons: Adolescent Artists With Autism In Art Education, Corrie Burdick

Teaching and Leadership - Dissertations

This research engages a combined qualitative methodology of arts-informed research and critical descriptive ethnography to study thirteen adolescent artists with autism as they engage in art making across multiple art education contexts. This study revealed the perceptions of stakeholders about art and autism that informed the access these adolescent artists had to art education and art materials. These perceptions included varying ideas of competence, ability and struggle associated with an identity as `autistic'. In the examination of these adolescents' experiences the engagement with art making and the role of art in the lives of these artists is explored. It is …

Child Neglect And Its Association With Subsequent Juvenile Drug And Alcohol Offense., Ellen Delara, J Propp, W Chen, K Corvo

Falk College Research Center

No abstract provided.

Insider Vol. 11 No. 1 Winter 2011, College Of Arts & Sciences

College of Arts and Sciences news

No abstract provided.

Improved Understanding Of Climate-Fi Re Relationships Along North America’S Pacifi C Coast, Marjie Brown

Joint Fire Science Program Briefs (2007-2012)

This research expanded our understanding of the climate/wildfi re relationship by identifying major climate controls and translating them into a practical tool, still under development, that managers can use for planning. The focus was on fi reclimate interactions from southern Oregon to Baja California, with emphasis placed on the infl uence of the Pacifi c North American (PNA) climate pattern. Researchers identifi ed and delineated differences in the way fi re activity responded to climate variability on a regional scale with the intent to improve fi re season forecasts along the Pacifi c coast. Strong correlations were found between certain …

Rising Temperatures Trigger Ecological Changes In The Boreal Forest Of Alaska, Shari Anstedt

Joint Fire Science Program Briefs (2007-2012)

Fundamentally different from the rest of the forest types in the United States, Alaska’s boreal forest covers a signifi cant amount of acreage in an increasingly variable climate. With its high latitude location, predictions reveal that this region will be the first to experience the effects of global climate change. In fact, natives of this region are already dealing with warmer temperatures and a changing landscape. As a result, researchers conducted a study to help gather more information about this area and to better understand the effects of climate change and how those effects influence fire and fuels management. An …

Mastication On Red Mountain: Investigating Fuel Loads And Fire Effects, Shari Anstedt

Joint Fire Science Program Briefs (2007-2012)

Although complete fire exclusion is a thing of the past in the Sierra Nevada, fire and fuel managers must still contend with dense forests and higher fuel loads that have built up over time. Controlled fire is a helpful fuel reduction method, but it can be tricky to manage, especially in an area with excessive fuels, or in plantations with trees having smaller diameters and lower crowns, which are more susceptible to heat damage. Mastication can also be a useful fuel treatment and has become a popular alternative, but includes its own set of drawbacks and uncertainties. Since little research …

Assessing Post-Fire Treatment Effects And Burn Severity On The Sandy Loam Soils Of Oregon, Shari Anstedt

Joint Fire Science Program Briefs (2007-2012)

Fire helps reduce dead and accumulated vegetation and enriches the soil by releasing nutrients bound in litter. But when fuel loads are too high and wildfi res burn too hot, problems may arise. A perfect example of this is the 2003 Booth and Bear Butte (B&B) fire in central Oregon, which consumed more than 90,000 acres of mixed conifer forest. On the surface, the effects on trees and vegetation seemed obvious, but what about the wildfi re effects on what we don’t see? How do post-fi re management activities support or impede forest recovery? Furthermore, how were the soils, and …

Ok-Fire: Weather-Based Decision Support For Wildland Fire Management, Shari Anstedt

Joint Fire Science Program Briefs (2007-2012)

There’s a lot of wildland in Oklahoma—and as a result, a lot of potential for fire. To help prepare for wildfire and perform fi re management activities, land managers previously used weather, fire danger, and smoke management products provided by the Oklahoma Mesonet, the state’s automated weather station network. But unfortunately, the products were not easily found or easy to use, and very little user training was provided. Fire managers also expressed the need for multi-day forecasting capabilities to help anticipate periods of high fire danger and severe wildfi re conditions and to improve pre-burn planning and management. These critical …

Fire History Study Reveals Surprises About Mixed-Pine Ecology In Eastern Upper Michigan, Joy Drohan

Joint Fire Science Program Briefs (2007-2012)

Mixed red and white pine forests in eastern Upper Michigan saw frequent fires, about every 50–60 years, before Euro-American settlement. Post-settlement, the fire cycle has lengthened and forest composition has shifted to include more jack pine and fi re-sensitive deciduous trees, increasing fuel loadings and changing wildlife habitat along the way. In cooperation with researchers and land managers at Seney National Wildlife Refuge, researchers at The Ohio State University are working out details of combining mechanical treatments with prescribed fire to restore mixed-pine forests dominated by red and white pine. In particular, their findings about red pine ecology could change …

Assessing Mechanical Mastication And Thinning-Piling-Burning Treatments On The Pinyon-Juniper Woodlands Of Southwestern Colorado, Shari Anstedt

Joint Fire Science Program Briefs (2007-2012)

New knowledge of fire regimes in the pinyon-juniper woodlands of the interior western United States has altered management views. Once known as being at low wildfire risk, these woodlands are now at a higher risk for severe wildfires because of high tree densities exacerbated by ongoing drought and region-wide bark beetle (Ips confusus) infestation. To help reduce fuels and fi re hazards and to create defensible space in the wildland urban interface, regional land managers have conducted thinning-piling-burning treatments. Recently, however, a different treatment has been used—mechanical mastication. Although mechanical mastication is typically more cost effective, there is concern about …

Following The Smoke Trail, Jake Delwiche

Joint Fire Science Program Briefs (2007-2012)

Public land administrators and air quality managers need better information on the potential contribution of wildland fires vs. anthropogenic sources on possible exceedances of air quality standards. To obtain more precise information in California, a composite network was established for monitoring ozone (O3), nitrogen dioxide (NO2), ammonia (NH3), gaseous nitric acid (HNO3) and particulate matter (PM). The network was located in the Sierra Nevada region of central California. The network provided data for estimates of distribution of air pollutants from urban and agricultural activities, and measured contributions of area wildland fi res on ground levels of pollutants. Information was also …

Fish And Forest Management: Not Necessarily At Odds, Joy Drohan

Joint Fire Science Program Briefs (2007-2012)

Resource managers of lands harboring sensitive aquatic species face tough choices. They could manage forests to reduce their wildfire potential, while possibly harming the sensitive species habitat, or they could leave forests untreated for wildfire, risking an uncharacteristic fire that may drastically alter critical aquatic species habitat. This study sought to develop a decision support framework to help managers understand the potential impacts of fire and resulting disturbances, such as debris flows, in this puzzle. The resulting fish population persistence model, Integrating Forests, Fish, and Fire (IF3), relies on existing geographic information system (GIS) data to discern where human impacts …

Can Archeology Survive A Fire?, Jake Delwiche

Joint Fire Science Program Briefs (2007-2012)

Most public lands include not only natural resource values, but also signifi cant cultural resources from both historic and prehistoric occupation. In some cases, the cultural resources are the reason for establishment of a park or monument. Responsibilities of the managers of these lands include protecting these cultural resources and balancing their protection with protection of the natural resources. This is essential to having a good understanding of the potential effect of fire— whether a prescribed fire or a wildfire—on the cultural resources. A recent scientifi c project funded by the Joint Fire Science Program studied the potential impact of …

Saving The Cypress: Restoring Fire To Rare, At-Risk Species, Christina Frame

Joint Fire Science Program Briefs (2007-2012)

Many populations of Baker and Macnab cypress are dying without signs of regeneration. The Forest Service is currently implementing controlled burning across a range of vegetation types in northern California, but because there is little information about how such treatments will affect rare, endemic plant communities, cypress stands have been excluded from such treatments. However, these fire-adapted species cannot survive extended periods of fire exclusion. To effectively manage the cypress and prevent further decline of the species, land managers need information on factors that promote cypress regeneration. The objectives of this study were to (1) determine if fire is indeed …

Evaluating Bark Beetle And Wildfi Re Dynamics In The Greater Yellowstone Ecosystem, Shari Anstedt

Joint Fire Science Program Briefs (2007-2012)

In the western United States, bark beetle outbreaks are at a record high—and of grave concern to forest managers and other stakeholders. There is a common belief that the high amounts of dead fuels produced by bark beetle infestations increase the chance of active crown fires. However, little is known about how bark beetle outbreaks and wildfire interact, and how that interaction influences the overall ecosystem structure and potential fi re behavior. To better understand bark beetle/wildfire dynamics, a study was conducted in beetle-infested areas of the Greater Yellowstone Ecosystem (GYE) in northwestern Wyoming and adjacent portions of Montana and …

A Project In Two Parts: Developing Fire Histories For The Eastern U.S. And Creating A Climate-Based Continental Fire Frequency Model To Fill Data Gaps, Christina Frame

Joint Fire Science Program Briefs (2007-2012)

Tree-ring dated fire scars provide long-term records of fire frequency, giving land managers valuable baseline information about the fire regimes that existed prior to Euro-American settlement. However, for the East, fire history data prove diffi cult to acquire because the generally moister climate of the region causes rapid decay of wood. In an endeavor to fill data gaps, the research team collected fire scar data in the states of Alabama, Louisiana, Kentucky, Tennessee, Iowa, Wisconsin, and Michigan. The second part of the project used this newly collected fi re history data combined with previously collected records to parameterize and calibrate …

Reducing Fuels Through Mulching Treatments: What Are The Ecological Effects?, Christina Frame

Joint Fire Science Program Briefs (2007-2012)

Many areas in the western U.S. are being thinned to reduce fire hazard and spread. Often the most economical solution for the disposal of the thinned biomass is to grind and leave the material onsite. These treatments are assumed to reduce the ability of the forest to carry a crown fire, but the effects of the added material on forest ecosystems are poorly known because such treatments do not have a natural analogue. Managers and the public are interested in understanding the impacts of the addition of this woody material on forest ecosystems so they can evaluate the benefi ts …