Digital Commons Network^™

A Multi Agent System For Flow-Based Intrusion Detection Using Reputation And Evolutionary Computation, David Hancock

Theses and Dissertations

The rising sophistication of cyber threats as well as the improvement of physical computer network properties present increasing challenges to contemporary Intrusion Detection (ID) techniques. To respond to these challenges, a multi agent system (MAS) coupled with flow-based ID techniques may effectively complement traditional ID systems. This paper develops: 1) a scalable software architecture for a new, self-organized, multi agent, flow-based ID system; and 2) a network simulation environment suitable for evaluating implementations of this MAS architecture and for other research purposes. Self-organization is achieved via 1) a reputation system that influences agent mobility in the search for effective vantage …

Multiple Integrated Navigation Sensors For Improving Occupancy Grid Fastslam, Christopher P. Weyers

Theses and Dissertations

An autonomous vehicle must accurately observe its location within the environment to interact with objects and accomplish its mission. When its environment is unknown, the vehicle must construct a map detailing its surroundings while using it to maintain an accurate location. Such a vehicle is faced with the circularly defined Simultaneous Localization and Mapping (SLAM) problem. However difficult, SLAM is a critical component of autonomous vehicle exploration with applications to search and rescue. To current knowledge, this research presents the first SLAM solution to integrate stereo cameras, inertial measurements, and vehicle odometry into a Multiple Integrated Navigation Sensor (MINS) path. …

A Comparison In The Accuracy Of Mapping Nuclear Fallout Patterns Using Hpac, Hysplit, Delfic Fpt And An Afit Fortran95 Fallout Deposition Code, April D. Miller

Theses and Dissertations

Four nuclear fallout mapping tools are studied to determine which tool predicts the most accurate fallout dose-rate contours with low computation time and resources. The four programs consist of the FORTRAN95 based Fallout Deposition Code (FDC), the Hazard Prediction and Assessment Capability's (HPAC) Nuclear Weapon (NWPN), the Defense Land Fallout Interpretative Code (DELFIC) Fallout Planning Tool (FPT) and the Hybrid Single-Particle Lagrangian Integrated Trajectory (HYSPLIT) Model. The models were compared to the Defense Nuclear Agency's (DNA) DNA 1251-1-EX, Compilation of Local Fallout Data from Test Detonations 1945-1962 Extracted from DASA 1251, using Warner and Platt's Measure of Effectiveness (MOE) method. …

Combating Biological Terrorism From Imported Food, Jeffrey S. Nelson

Theses and Dissertations

There is a threat that a terrorist or terrorist organization will use access to the US food supply to kill or sicken Americans by contaminating imported food products from Mexico. The food that Americans eat is coming more and more often from foreign countries such as Mexico. Foodborne diseases infect nearly fifty million people in the US each year, resulting in over three thousand deaths. There are many terrorist organizations that would like to deliberately contaminate American food. Drug cartels and terrorist organizations currently operate in Mexico, one of the leading food importers into the US. The purpose of this …

An Analytical Model Of Nanometer Scale Viscoelastic Properties Of Polymer Surfaces Measured Using An Atomic Force Microscope, Jacob B. Goldberg

Theses and Dissertations

The United States Air Force and the Department of Defense is increasingly interested in nanomaterials. To study these materials, one needs to measure the mechanics of materials on the nanoscale. Over the past few decades the atomic force microscope (AFM) has been used in various methods to establish local surface properties at the nanoscale. In particular, surface elasticity measurements are crucial to understanding nanoscale surface properties. Problems arise, however, when measuring soft surfaces such as polymers and biological specimens, because these materials have a more complex viscoelastic response. This research focuses on modeling an AFM dynamic nanoindentation experiment intended to …

Modeling Of Bacillus Spores: Inactivation And Outgrowth, Alexis X. Hurst

Theses and Dissertations

This research models and analyzes the thermochemical damage produced in Bacillus spores by short, high-temperature exposures as well the repair process within damaged Bacillus spores. Thermochemical damage in spores is significantly due to reaction with water, hydrolysis reactions. Applying heat to the spore causes absorbed and chemically bound water molecules become mobile within the spore. These mobile water molecules react by hydrolysis reactions to degrade DNA and enzyme molecules in the spore. In order to survive the thermal inactivation, the spore must repair the damaged DNA during spore germination. The DNA repair process, as well as other germination functions, is …

Nuclear Enterprise Performance Measurement, Andrew S. Hackleman

Theses and Dissertations

The criticality of the United States Air Force nuclear enterprise demands that commanders have the best possible understanding of system performance, both in the aggregate and at the drill-down levels sufficient to make timely corrective actions when warranted. We model a strategy-linked measurement system for nuclear enterprise sustainment. We propose a new Aggregation "h" method for aggregating performance metrics using United States Air Force approved or adapted metrics that possess the capability to weight metrics, as well as compare performance between organizations and within the same organization over time. We demonstrate our method with generated performance data designed to test …

Migration Issues In The Democratic Republic Of Congo, Michael J. Thompson

Theses and Dissertations

Since the end of the Cold War, the number of weak and failing states has increased significantly. The United States (US) military has been deployed in multiple nation states in an effort to prevent these weak states from collapsing into chaos. This thesis explores one of the driving factors of state collapse, net migration, to gauge how US foreign policy might be employed to reduce the flow of people out of a country. To demonstrate the foreign policies and their effects, a pilot model was constructed using a system dynamics methodology. The Democratic Republic of Congo (DRC) was selected as …

Modeling Enhanced Storage Of Groundwater Contaminants Due To The Presence Of Cracks In Low Permeability Zones Underlying Contaminant Source Areas, Jeremy M. Miniter

Theses and Dissertations

Throughout DoD, chlorinated aliphatic hydrocarbons (CAHs), a type of Dense Non-Aqueous Phase Liquid (DNAPL), have been frequently used. In the subsurface, spilled DNAPLs may pool atop low permeability clay layers. In this study a numerical model is constructed using the Groundwater Modeling System to assess how cracks in the clay, either pre-existing or the result of DNAPL-clay interactions, might impact a dissolved CAH plume generated by the DNAPL source. The conceptual model posits a DNAPL source in a high permeability sand aquifer sitting atop a low permeability clay layer. The model assumes dissolved CAH generated by the DNAPL is transported …

Composite Aircraft Life Cycle Cost Estimating Model, Daniel B. Lambert

Theses and Dissertations

Composite materials are beginning to comprise a greater percentage of structural materials used throughout aircraft production. The increased usage of composites has led individuals within the Air Force community to revisit aircraft life cycle cost, LCC, models. A series of affordability initiatives has culminated in significant evidence over the last decade to better quantify the impact of primarily composite structures in aircraft. The Advanced Composite Cargo Aircraft, ACCA, a research effort sponsored by the Air Force Research Lab, attempted to determine the impact of part size and large scale composite components on LCC for cargo aircraft. This research evaluates the …

Role Of Wnt5a And Possible Pathway Of Action Through Ror2 In Proximodistal Outgrowth Of The Limb, Tiffanie M. Dahl

Theses and Dissertations

Despite over 60 years of study, the molecular pathways and mechanisms governing limb outgrowth and patterning remain poorly understood. Fgfs expressed in the AER are known to be necessary and sufficient for proximodistal limb outgrowth and have been proposed to have a chemoattractive role. Wnt5a is a secreted factor which is expressed in a gradient in the distal limb with the highest concentration next to the AER. The presence of the AER is necessary to establish this gradient. Expression of Wnt5a in a concentration dependant manner can be induced in the limb through the implantation of a bead soaked in …

Ecological Studies Of Wolves On Isle Royale, 2010-2011, John A. Vucetich, Rolf O. Peterson

Ecological Studies of Wolves on Isle Royale

Annual Report 2010-2011

Characterization And In Vitro Toxicity Of Copper Nanoparticles (Cu-Nps) In Murine Neuroblastoma (N2a) Cells, Sitao Veronica Brownheim

Theses and Dissertations

Nanomaterials, classified as materials within the 1 - 100 nanometer range, have seemingly endless applications. It is very important to the Air Force to increase the understanding of Cu-NPs and the possible health impacts from nanomaterial exposure prior to wide-spread industry and military use. Therefore, the purpose of this research is to thoroughly characterize the properties of three different copper samples upon suspension into aqueous solutions over time: Cu-NPs (Cu 25 nm), CuO-NPs (CuO 40 nm), and Cu-MSP (Cu 500nm). Additionally, this research seeks to observe in vitro effects upon murine neuroblastoma cells (N2A) by these three types of particles …

Non-Identity-Mediated Crispr-Bacteriophage Interaction Mediated Via The Csy And Cas3 Proteins, Kyle C. Cady, George A. O'Toole

Dartmouth Scholarship

Studies of the Escherichia, Neisseria, Thermotoga, and Mycobacteria clustered regularly interspaced short palindromic repeat (CRISPR) subtypes have resulted in a model whereby CRISPRs function as a defense system against bacteriophage infection and conjugative plasmid transfer. In contrast, we previously showed that the Yersinia-subtype CRISPR region of Pseudomonas aeruginosa strain UCBPP-PA14 plays no detectable role in viral immunity but instead is required for bacteriophage DMS3-dependent inhibition of biofilm formation by P. aeruginosa. The goal of this study is to define the components of the Yersinia-subtype CRISPR region required to mediate this bacteriophage-host interaction. We show that the Yersinia-subtype-specific CRISPR-associated (Cas) proteins …

Chimes: March 11, 2011, Calvin College

Chimes

Limelight shines on Calvin stars by Griffin Jackson

Screenings could save student athletes by Allison Schepers

Discovery completes final flight by Katie Faber

Nation of Palestine makes bid for statehood at the United Nations by Christine Bennett

Knights fall in second round of NCAA tourney by Derek Neice

Organizations

Ethics and Animals

No abstract provided.

Article Review Of Evolution, Animals, And The Basis Of Morality, Inquiry, Dale Jamieson

Ethics and Animals

No abstract provided.

Prefatory Notes

Ethics and Animals

No abstract provided.

Conference Program

Women's Summit Presented by Bryant University

Women's Summit 2011 Conference Program with keynote speaker and sessions descriptions.

Synthesis Of 2-(Substituted Phenyl)-355-Trimethylmorpholine Analogues And Their Effects On Monoamine Uptake Nicotinic Acetylcholine Receptor Function And Behavioral Effects Of Nicotine, F. Ivy Carroll, Ana Z. Muresan, Bruce E. Blough, Hernan A. Navarro, S. Wayne Mascarella, J. Brek Eaton, Xiaodong Huang, M. Imad Damaj, Ronald J. Lukas

Translational Neuroscience

Toward development of smoking cessation aids superior to bupropion (2), we describe synthesis of 2-(substituted phenyl)-3,5,5-trimethylmorpholine analogues 5a-5h and their effects on inhibition of dopamine, norepinephrine, and serotonin uptake, nicotinic acetylcholine receptor (nAChR) function, acute actions of nicotine, and nicotine-conditioned place preference (CPP). Several analogues encompassing aryl substitutions, N-alkylation, and alkyl extensions of the morpholine ring 3-methyl group provided analogues more potent in vitro than (S,S)-hydroxybupropion (4a) as inhibitors of dopamine or norepinephrine uptake and antagonists of nAChR function. All of the new (S,S)-5 analogues had better potency than (S,S)-4a as blockers of acute nicotine analgesia in the tail-flick test. …

Commonwealth Times 2011-03-10

Commonwealth Times, 1969-

No abstract provided.

Spartan Daily March 10, 2011, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily (School of Journalism and Mass Communications)

Volume 136, Issue 24

Novel Strains Of Mice Deficient For The Vesicular Acetylcholine Transporter: Insights On Transcriptional Regulation And Control Of Locomotor Behavior, Christina Martins-Silva, Xavier De Jaeger, Monica S. Guzman, Ricardo D. F. Lima, Magda S. Santos, Christopher Kushmerick, Marcus V. Gomez, Marc G. Caron, Marco A. M. Prado, Vania F. Prado

Anatomy and Cell Biology Publications

Defining the contribution of acetylcholine to specific behaviors has been challenging, mainly because of the difficulty in generating suitable animal models of cholinergic dysfunction. We have recently shown that, by targeting the vesicular acetylcholine transporter (VAChT) gene, it is possible to generate genetically modified mice with cholinergic deficiency. Here we describe novel VAChT mutant lines. VAChT gene is embedded within the first intron of the choline acetyltransferase (ChAT) gene, which provides a unique arrangement and regulation for these two genes. We generated a VAChT allele that is flanked by loxP sequences and carries the resistance cassette placed in a ChAT …

The Functions Of Guilt And Shame In Juan José Millás' El Mundo And My Olive-Green Fridge And I: The Posthuman Identity In El Púgil, Constantin Cristian Icleanu

Theses and Dissertations

In his celebrated 2007 novel El mundo, Juan José Millás tells the story of the development of Juanjo, a simulacrum of himself, and describes a series of negative developments that the protagonist faces in his childhood. While much has been written about Millás and the “testimonial realism” of his literary generation, little has been written about the psychological factors that influence his characters. In this paper I analyze Juanjo's development as understood from the gradation of guilt to shame, depression, and later suicidal thoughts. Because Juanjo is not able to find an appropriate mechanism of release for his guilt, …

March 10, 2011, Council On Academic Affairs

Minutes

No abstract provided.

Reduced Activity Of Multiple Endocrine Disrupting Compounds: 17Β-Estradiol And Bisphenol A With A Chemi-Luminescent Assay, Anna C. Ortiz^, Roberto J. De La Torre-Roche, Marc B. Cox, Wen-Yee Lee*

COURI Symposium Abstracts, Spring 2011

The concern about the impacts of endocrine disrupting compounds (EDCs) in the environment has increased recently with their high occurrence in surface waters and sex changes in various aquatic organisms. EDCs include ubiquitously used pharmaceuticals and personal care products, such as soap, detergents, contraceptives, and other medicines, which are released constantly into the environment, in waste water treatment plant effluent. Though toxicological effects of these individual, EDCs have been studied, knowledge on how these chemicals interact together in the environment is very limited. The objective of this project is to study the multi-residue effect of EDCs using a chemi-luminescent yeast …

Changes In Dissolved Organic Carbon (Doc) In Arctic Tundra Ponds Over The Past 40 Years, Gabriela Contreras^, Vanessa L. Lougheed*

COURI Symposium Abstracts, Spring 2011

With a warming Arctic, degradation of permafrost is expected to release organic and inorganic materials into aquatic ecosystems; however, there are few long-term datasets with which to test this prediction. The Arctic tundra ponds at the International Biological Program (IBP) site in Barrow, Alaska, studied for the first time in the 1970s, represent one of the very few locations in the Arctic where long-term data are available on freshwater ecosystem structure and function.

Dissolved Organic Carbon (DOC) is used to describe the thousands of dissolved compounds found in water that derive from organic materials. The objective of this study was …

Johnson-Sea-Link Submersibles Tools For Research And Discovery: Summary Of Users, Publications, Documentaries And Testimonials., John K. Reed, Tamara M. Frank

Faculty Scholarship

This document was compiled by various scientists and users of the Johnson-Sea-Link (JSL) submersibles. This document is not inclusive but presents some highlights of major discoveries, publications, and grants made possible by use of Harbor Branch Oceanographic Institution's (HBOI) research submersibles. The Johnson-Sea-Link submersibles were the cornerstone of Harbor Branch when Edwin Link invented and built the submersibles at HBOI (Harbor Branch Foundation) nearly 40 years ago. The Johnson-Sea-Link submersibles have resulted in international acclaim for Harbor Branch from recent research discoveries to Discovery Channel documentaries. The ocean going and deep-water capabilities of HBOI have been a core strength of …

A Novel Use Of Digoxin Immune Fab Fragment In Identification And Isolation Of An Endogenous Digitalis-Like Factor Found In Preeclampsia, Moana Lee Hopoate-Sitake

Theses and Dissertations

The mechanisms mediating the hypertension of preeclampsia (PE) are unclear. Endogenous digitalis-like factors (EDLFs) are specific sodium pump (SP) inhibitors implicated in essential and experimental hypertension, but they have not been fully explored in the setting of PE. This study uses a digoxin antibody Fab fragment to address the question of whether such factors are present and increased in PE, to investigate a possible treatment of PE, and to isolate and characterize all EDLFs present in PE. Sera and placenta from women with PE did show a significant increase in SP inhibition in comparison to women with normal pregnancy and …

Somatoform Disorder: Treatment Utilization And Cost By Mental Health Professions, Lori Barker Morton

Theses and Dissertations

Somatoform disorder is a prevalent mental health disorder in the United States. This disorder costs the United States one billion dollars annually. Medical providers report somatoform disorder is difficult to treat. Previous studies have shown that Cognitive Behavioral Therapy (CBT) is effective at reducing symptoms of somatoform disorder. Unfortunately, little research has been done on treatment outcomes and cost of somatoform disorder, particularly by profession to reduce health care costs for somatoform patients and providers. Administrative data from CIGNA for 149 somatoform disorder cases were analyzed to determine the cost, number of sessions, dropout rates, and recidivism rates for somatoform …