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Mutant Tdp-43 In Motor Neurons Promotes The Onset And Progression Of Als In Rats, Cao Huang, Jianbin Tong, Fangfang Bi, Hongxia Zhou, Xu-Gang Xia

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration, which ultimately leads to paralysis and death. Mutation of TAR DNA binding protein 43 (TDP-43) has been linked to the development of an inherited form of ALS. Existing TDP-43 transgenic animals develop a limited loss of motor neurons and therefore do not faithfully reproduce the core phenotype of ALS. Here, we report the creation of multiple lines of transgenic rats in which expression of ALS-associated mutant human TDP-43 is restricted to either motor neurons or other types of neurons and skeletal muscle and can be switched on and off. …

Inside Nfl Marriages: A Seven Year Ethnographic Study Of Love And Marriage In Professional Football, Rachel Anne Binns Terrill

USF Tampa Graduate Theses and Dissertations

When women marry NFL players and subsequently become NFL wives, they are thrust out of the lives they have known and into a form of secondary socialization among other NFL wives. In this dissertation, I use ethnography and narrative inquiry, the first- person narratives of four NFL wives, interactive interviews with dozens of NFL wives, friendship as method, and my personal autoethnographic experiences to describe the social interactions between NFL wives, the themes of their marriages, and the trajectories of their identity formation and transformation of NFL wives during their time in the league.

I also use autoethnography and writing …

Glass V. State Respondent's Brief Dckt. 38079

Not Reported

No abstract provided.

State V. May Appellant's Brief Dckt. 38835

Not Reported

No abstract provided.

Trauma Care In Tennessee; 2011 Report To The 108th General Assembly, Tennessee. Department Of Health.

Trauma Care in Tennessee

No abstract provided.

Faculty Senate Executive Committee Agenda, December 12, 2011, Utah State University

Faculty Senate & Faculty Senate Executive Committee

• ASUSU Report
• Council on Teacher Education Report
• Scholarship Advisory Board Report
• EPC Items
• PRPC 402.3.2; 402.3.4 Vacancies (second reading)
• Open Access
• Overload Compensation

Faculty Senate Executive Committee Minutes, December 12, 2011, Utah State University

Faculty Senate & Faculty Senate Executive Committee

• ASUSU Report - Erik Mikkelsen
• Council on Teacher Education Report - Francine Johnson
• Scholarship Advisory Board Report - Patti Kohler
• EPC Items - Larry Smith
• PRPC 402.3.2; 402.3.4 Vacancies (second reading) – Terry Peak
• Open Access – Richard Clement and Flora Shrode
• Overload Compensation – Raymond Coward

Distinct Peripheral Blood Rna Responses To Salmonella In Pigs Differing In Salmonella Shedding Levels: Intersection Of Ifng, Tlr And Mirna Pathways, Ting-Hua Huang, Jolita J. Uthe, Shawn M. D. Bearson, Cumhur Yusuf Demirkale, Dan Nettleton, Susan Knetter, Curtis Christian, Amanda Ramer-Tait, Michael J. Wannemuehler, Christopher K. Tuggle

Department of Food Science and Technology: Faculty Publications

Transcriptomic analysis of the response to bacterial pathogens has been reported for several species, yet few studies have investigated the transcriptional differences in whole blood in subjects that differ in their disease response phenotypes. Salmonella species infect many vertebrate species, and pigs colonized with Salmonella enterica serovar Typhimurium (ST) are usually asymptomatic, making detection of these Salmonella-carrier pigs difficult. The variable fecal shedding of Salmonella is an important cause of foodborne illness and zoonotic disease. To investigate gene pathways and biomarkers associated with the variance in Salmonella shedding following experimental inoculation, we initiated the first analysis of the whole …

Colon V. State Appellant's Brief Dckt. 38746

Not Reported

No abstract provided.

State V. Arthur Respondent's Brief Dckt. 38339

Not Reported

No abstract provided.

Security Cooperation Poorly Defined, Nathan L. Fenell

Master's Theses

Security cooperation is a vital component to the national security of the United States. Despite this fact, insufficient military or academic attention has been applied to the subject. The academic and professional void created by this inattention has led academic, journalistic, and military professionals to misuse the term security cooperation, and stray from its doctrinal description as defined by the Department of Defense Dictionary and Associated Military Terms. The academic rigor required to properly express the concept of security cooperation as a peace-time strategy has been absent from both the Department of Defense, and the Department of State, and …

Courting Disaster For Votes, Ishrat Husain Dr.

Faculty Research - Newspaper and Magazine Articles

Prime Minister Yousuf Raza Gilani is reported to have told the Pakistan Peoples’ Party (PPP) provincial assembly members from Punjab that the ban on recruitment in the federal government would be removed. Job quotas will be given to each Member Provincial Assembly (MPA) in addition to the substantial grants from the exchequer for development work in their respective constituencies.

This seems to be the first salvo fired by the government in preparation for the elections to be held in the next 12-15 months – if all goes well. These election-specific preparations should remind us of 2007 when a strong economy …

The Infant Orienting Response As It Relates To Mother-Infant Co-Regulation And Attachment, Sarah Ann Ahlander Stone

Theses and Dissertations

This study examined the relationship between 6-month old infants' orienting response to maternal arm-restraint (as measured by bradycardia), the quality of mother-infant communication at 6 and 9 months (as measured by the Relational Coding System) and attachment at 12 months (as measured by the Strange Situation Procedure). As positive mother-infant communication increases, the chances the infant will experience bradycardia increases. As negative mother-infant communication increases, the chances that the infant will experience bradycardia decreases. For mothers and infants who have more positive communication patterns, orienting response to the maternal arm-restraint suggests that maternal disruption of infant activity was a novel …

Essential Analytical Parameters In The Gas Chromatographic-Mass Spectrometric Analyses Of Complex Materials: Biofuels And Fungicide Treated Wood, Jana St'avova

Theses and Dissertations

Accurate analytical methods are needed to evaluate the quality of newly developed biofuels. In this dissertation, a method employing gas chromatography with simultaneous flame ionization and mass spectrometry detection (GC-FID/MS) was developed for detailed characterization of complex biofuel intermediates generated upon crop oil pyrolysis. An efficient separation of individual compounds was achieved using a cryogenic cooling and single temperature gradient of 2.5°C min-1. Two standard mixtures were designed for accurate identification. A programmed temperature vaporizer and a designed calibration standard (20 representative components) minimized the compound discrimination, and thus enabled accurate quantification of over 250 species. Besides hydrocarbons, the unidentified …

Adrenergic Receptor Modulation Of Lipopolysaccharide-Mediated Inflammatory Responses, Laurel A. Grisanti

Theses and Dissertations

The adrenergic receptor (AR) family is a group of G protein-coupled receptors activated by the endogenous catcholamines epinephrine (Epi) and norepinephrine (NE). There are nine different AR subtypes that are differentially expressed throughout the body including on immune cells. Levels of Epi and NE are known to influence immune responses however, the AR subtype expression and function are not well characterized. The purpose of this study was to: 1) characterize the AR subtype expression profile on monocytes and macrophages; 2) elucidate how AR activation regulates cytokine/chemokine production; and 3) determine the mechanism(s) by which individual AR subtypes modulate cytokine production. …

Gpsa Bylaws, 2011, Graduate And Professional Student Association

GPSA Documents

No abstract provided.

Age Dependent Spatial Characteristics Of Epileptiform Activity In Malformed Cortex, L. Andrew Bell

Theses and Dissertations

Developmental cortical malformations are a major cause of intractable seizures. Determining the location and timing of susceptibility for epileptiform activity is critical to identifying what mechanisms contribute to epileptogenesis in any model. Using the freeze lesion rat model of polymicrogyria, we have identified, in lesioned cortex, these two aspects of epileptogenesis. Previous studies have demonstrated that epileptiform activity cannot be evoked prior to postnatal day (P) 12, but the malformed cortex is more susceptible to seizures as early as P10. An increase in excitatory afferents to the epileptogenic zone occurs before the onset of network epileptiform activity. Whether or not …

Reflecting On Appeals On Questions Of Law Arising Out Of Domestic Arbitration Awards, Darius Chan, Paul Tan

Research Collection Yong Pung How School Of Law

Domestic arbitration awards rendered under the Arbitration Act (Cap 10, 2002 Rev Ed) (“the Act”) can be subject to appeal on a question of law arising out of an award. Unless parties consent, an appeal can only be brought with the leave of court.

An Evaluation Of The Effectiveness Of A Medical School Musculoskeletal Curriculum At An Academic Medical Center, Andy Lalka, Frank A. Scott, Ryan Caldwell, Andrew Black

Higher Learning Research Communications

Background: Musculoskeletal disorders are common medical problems encountered by physicians and affected 126.6 million Americans in 2012. Musculoskeletal education has inadequate in United States medical schools. Objective: To determine the musculoskeletal competency of third year medical students. Methods: A cross-sectional 25-question nationally validated musculoskeletal competency exam was given to the third year medical students. A survey was given to second and third year medical students to assess students’ level of interest in musculoskeletal medicine and their feedback regarding the curriculum. Results: The mean score of the competency exam was 69.0%. There was 48/107 (44.9%) students’ who reached the minimum passing …

Connect - October-December 2010

Connect

Click the DOWNLOAD button to obtain a PDF of this issue.

Agglomeration Economics: Small Establishments/Big Effects: Agglomeration, Industrial Organization And Entrepreneurship, Stuart S. Rosenthal, William Strange

Economics - All Scholarship

No abstract provided.

Investigation Of Rti Effectiveness, Patricia L. Murphy

Morehead State Theses and Dissertations

An applied project submitted in partial fulfillment of the requirements for the degree of Education Specialist at Morehead State University by Patricia Murphy on December 11, 2011

Deafdigest: Gold Edition, December 11, 2011, Barry Strassler

DeafDigest Gold 2011

No abstract provided.

Health And Wellness Using Occupations To Explore Internal Motivators For Change, Shayal Ram, Susan Macdermott, Becki Cohill, Karen Park

Fall 2020 Virtual OTD Capstone Symposium

The purpose of this capstone project was to create an occupation-based program that could be integrated into the lifestyle patterns of adults to potentially assist reducing the risk of Alzheimer’s disease (AD). The number of Americans living with AD is expected to grow up to 16 million by 2050 (Smallfield & Heckenlaible, 2017). The risk for developing the disease could be reduced through lifestyle modifications (Hussenoeder & Riedel-Heller, 2018). Using occupation as a means for health promotion and disease prevention is an emerging area for occupational therapy practice (AOTA, 2014). This capstone sought to increase awareness of internal motivators that …

Deafdigest: Blue Edition, December 11, 2011, Barry Strassler

DeafDigest Blue 2011

No abstract provided.

State V. Hanson Clerk's Record Dckt. 38512

Idaho Supreme Court Records & Briefs, All

No abstract provided.

Script, Commencement Convocation, December 11, 2011, University Of South Florida St. Petersburg

USF St. Petersburg Graduations and Commencements

A script for the University of South Florida St. Petersburg commencement ceremony on December 11, 2011.

Commencement Convocation Program, St. Petersburg Campus, December 11, 2011, University Of South Florida St. Petersburg

USF St. Petersburg Graduations and Commencements

King O'Neal Awards: Kara B. Harmon, Kristin E. Perkins; Outstanding Graduate: Ivan Bengtson; Regional Chancellor's Award for Civic Leadership: Vyrle Davis

Preserving Euskera In A Globalized World: Determining The Long-Term Efficacy Of Multilingual Schools In The Basque Country, Spain, Olivia Destrades Mendoza

Masters Theses

The Basque Country, Spain is a linguistically unique region where the minority indigenous language, Euskera, competes alongside the dominant state language, Castilian, and a lingua franca, English, for prestige and status. Following a history of cultural and linguistic repression and marginalization, the Basque community has, in the past 30 years, begun to reintroduce Euskera into new, multilingual school systems in order to teach, preserve and maintain their heritage language, while simultaneously acquiring English as an important language for global communication. This multimethod, qualitative study takes data from 36 survey respondents and five interview participants from the Basque Country, and triangulates …

29 Trillion: A Detailed Look At The Fed's Bailout By Funding Facility And Recipient, James Andrew Felkerson

Documents

No abstract provided.