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Proteomic Signatures Of Human Oral Epithelial Cells In Hiv-Infected Subjects, Elizabeth Yohannes, Santosh K. Ghosh, Bin Jiang, Thomas S. Mccormick, Aaron Weinberg, Edward Hill, Faddy Faddoul, Mark R. Chance

Faculty Scholarship

The oral epithelium, the most abundant structural tissue lining the oral mucosa, is an important line of defense against infectious microorganisms. HIV infected subjects on highly active antiretroviral therapy (HAART) are susceptible to comorbid viral, bacterial and fungal infections in the oral cavity. To provide an assessment of the molecular alterations of oral epithelia potentially associated with susceptibility to comorbid infections in such subjects, we performed various proteomic studies on over twenty HIV infected and healthy subjects. In a discovery phase two Dimensional Difference Gel Electrophoresis (2-D DIGE) analyses of human oral gingival epithelial cell (HOEC) lysates were carried out; …

A Leucine-Enriched Diet Enhances Overload-Induced Growth And Markers Of Protein Synthesis In Aged Rat Skeletal Muscle, Rengfei Shi, Hoke Whitworth, William Mixon, Scott E. Gordon

International Journal of Exercise Science: Conference Proceedings

Introduction: The hypertrophic response to overload in fast-twitch skeletal muscle is impaired in aged humans and rats, and impaired protein synthesis pathway activation is hypothesized to be a contributing factor. Muscle growth occurs when protein synthesis exceeds protein degradation. Dietary supplementation of the essential amino acid leucine has been shown to enhance protein synthesis in both young and aged skeletal muscle. Leucine acts in part by activating mammalian target of rapamycin (mTOR; a key upstream regulator of protein synthesis pathways) as well as by attenuating the activation of 5'-AMP-activated protein kinase (AMPK; a negative regulator of mTOR and protein synthesis). …

A Leucine-Enriched Diet Enhances Overload-Induced Growth And Suppresses Markers Of Protein Degradation In Aged Rat Skeletal Muscle, Scott E. Gordon, William Mixon, Hoke Whitworth, Rengfei Shi

International Journal of Exercise Science: Conference Proceedings

Introduction: The hypertrophic response to overload in fast-twitch skeletal muscle is impaired in aged humans and rats, and upregulation of protein degradation pathways are hypothesized to be a contributing factor. Muscle growth occurs when protein synthesis is greater than protein degradation. Dietary supplementation of the essential amino acid leucine has been shown to reduce protein degradation in both young and aged skeletal muscle. Specifically, leucine acts in part by attenuating 5'-AMP-activated protein kinase (AMPK) activation as well as the translocation of the forkhead box transcription factor 3A (FoxO3, known to promote transcription of mRNAs encoding degradation pathway proteins) to the …

Genetic Regulation Of Myofiber Hypertrophy?, Anna Thalacker-Mercer, Xiangqin Cui, Michael Stec, Edward Merritt, Marcas Bamman

International Journal of Exercise Science: Conference Proceedings

Introduction. Progressive, resistance exercise training (RT) induces skeletal muscle hypertrophy, increases strength, power, and quality of muscle, and is potentially the most promising method to regenerate and re-grow muscle in populations suffering from involuntary atrophy. However, we have previously shown that there is a large degree of intersubject variability for myofiber hypertrophy in response to RT with adults having no response [-16μm2 (mean myofiber growth), Non], a modest response (1111μm2, Mod), or an extreme hypertrophic response (2475μm2, Xtr). Underlying mechanisms for this differential growth response are largely unknown. Therefore, the purpose of this study was to determine whether differences in …

Effects Of Multivitamin Supplementation On Heart Rate Response In Aerobically Untrained College Aged Students, Greg A. Ryan, Charles P. Katica, Stacy H. Bishop, Robert L. Herron, Andy M. Bosak, Mark Sloniger

International Journal of Exercise Science: Conference Proceedings

Multivitamin use is increasingly prevalent in the US among most every population. Yet, previous research noted no performance benefits among individuals following a supplementation period. This study focused on the potential physiological benefits from a three week multivitamin supplementation period using 24 (20.9 ± 2.6yr) aerobically untrained college aged students. Subjects were divided equally into three groups (placebo = PL, multivitamin = MV, control = CL) and asked to perform separate eight minute bouts of exercise, consisting of six min of moderate (60%VO2max) intensity followed immediately by two min of high (85%VO2max) intensity exercise on a cycle ergometer. Following the …

Body Composition, Physical Activity And Fitness In Children With Moderate-To-Severe Intellectual Disability, Sigurbjorn A. Arngrimsson, Ingi T. Einarsson

International Journal of Exercise Science: Conference Proceedings

Introduction: The prevalence of overweight and obesity has been rising in most parts of the world over the past two decades (1, 2). This rise could pose even a greater problem for people with intellectual disability (ID) because they are more likely to be obese than people without ID (3). Furthermore, research has shown that a sedentary lifestyle is more prevalent among people with ID than otherwise healthy people in modern society (4). In the general population, the adverse effects of obesity on health begin early in life and physical inactivity and adiposity are associated with metabolic diseases and cancers …

The Physiological Stress Response To Anaerobic Exercise Is Altered Following Sodium Bicarbonate Supplementation, Dan J. Peart, Richard Kirk, Angela Hillman, Bryna Chrismas, Leigh Madden, Jason Siegler, Rebecca Vince

International Journal of Exercise Science: Conference Proceedings

Sodium bicarbonate (NaHCO3) is a nutritional aid that is proposed to enhance performance by reducing the state of exercise induced acidosis, however research is currently equivocal. Despite this, most research still focuses on its effects upon performance, and not whether the reduced acidosis impacts upon any other factors related to exercise. There is some research to suggest that such a reduction in [H+] can attenuate a number of physiological stress pathways such as stress hormones (1, 4), heat shock protein 72 (HSP72) and oxidative stress (3), suggesting a potential role in exercise recovery. However there are some limitations with this …

Two Days, Two Marathons: Superman?, Marco Vescovi M.D., Serena Benzo M.D., Daniele Bronzini, Flavia Bruttini M.D., Antonio Mortara, Ioanna Nakou M.D., Monica Vescovi M.D.

International Journal of Exercise Science: Conference Proceedings

The river marathon races are characterized by a duration longer than two hours, with intermissions at predetermined distances depending on the route. In these intermissions the athletes make portages where the competitors carry their canoes in a foot race with a distance of about 150 meters, and then they resumes paddling.

C-Reactive Protein And The Disease Analog Model May Identify Predisposed Pre-Obese African-American Women, James W. Navalta, Scott Lyons, Sharon E. Whitlock, Demetrice D. Kirkwood, Scott W. Arnett, Mark A. Schafer

International Journal of Exercise Science: Conference Proceedings

While the obesity rate in the Unites States has been reported to have hit a plateau, the overall percentage of obese Americans remains alarmingly high (27% self-reported, 33% population estimate). While the subgroup with the highest 2010 obesity rate is Black, non-Hispanic women (41.9%), there remains a disparity in the research with regards to this population group. The implication of an elevated obese population puts a strain on health care, overall quality of life, and is associated with a number of other co-morbidities. Given this background, pilot work to evaluate a disease analog model for obesity would be useful with …

Food Matters: Clinical Education And Advocacy Training

Population Health Matters (Formerly Health Policy Newsletter)

No abstract provided.

Health Policy Newsletter Fall 2011 Download Full Pdf

Population Health Matters (Formerly Health Policy Newsletter)

No abstract provided.

2011 November 15 - Medical Student Education Committee Minutes, Medical Student Education Committee, East Tennessee State University

Medical Student Education Committee Minutes

No abstract provided.

Daily Eastern News: November 15, 2011, Eastern Illinois University

November

No abstract provided.

November 15, 2011 Aasu Graduate Affairs Committee Minutes, Armstrong Atlantic State University

Armstrong Office of the Registrar: Graduate Affairs Committee Minutes (Archived)

November 15, 2011 AASU Graduate Affairs Committee Minutes

Describing Connections Between Science Content And Future Careers: Implementing Texas Curriculum For Rural At-Risk High School Students Using Purposefully-Designed Field Trips, Tommye Hutson, Susan Cooper, Tony Talbot

The Rural Educator

The state of Texas has an ‘essential knowledge’ component in some high school science courses indicating that students be able to describe connections between academic science content and future jobs or training through effective exposure to course content. The participants in this study were from a small rural high school in central Texas. Each was labeled as ‘at-risk’ and self-identified an inability to describe those types of connections after earning credit in more than one science course with that ‘essential knowledge’ component. A career-focused field trip to a local vocational/technology training center was designed to address that particular deficit. This …

End-Of-Life Decision-Making In Canada: The Report By The Royalsociety Of Canada Expert Panel On End-Of-Life Decision-Making, Udo Schüklenk, Johannes J. M. Van Delden, Jocelyn Downie, Sheila A. M. Mclean, Ross Upshur, Daniel Weinstock

Reports & Public Policy Documents

This report on end-of-life decision-making in Canada was produced by an international expert panel and commissioned by the Royal Society of Canada. It consists of five chapters.

Chapter 1 reviews what is known about end-of-life care and opinions about assisted dying in Canada.

Chapter 2 reviews the legal status quo in Canada with regard to various forms of assisted death.

Chapter 3 reviews ethical issues pertaining to assisted death. The analysis is grounded in core values central to Canada's constitutional order.

Chapter 4 reviews the experiences had in a number of jurisdictions that have decriminalized or recently reviewed assisted dying …

Spartan Daily November 15, 2011, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily (School of Journalism and Mass Communications)

Volume 137, Issue 42

The George-Anne, Georgia Southern University

The George-Anne

• Eagles Capture SoCon Title
• Views
• Arts
• Classifieds
• Puzzles/ Comics
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Traversing Swanton Road, 6th Ed., James A. West

Academic, Government & Associated Organizational Research Resources

Situated at the northwest end of Santa Cruz County and occupying circa 30 square miles of sharply contrasted terrain, the Scott Creek Watershed concentrates within its geomorphological boundaries, at least 10-12% of California's flora, both native and introduced. Paradoxically, the use/abuse that the watershed has sustained over the past 140+ years, has not necessarily diminished the biodiversity and perhaps parallels the naturally disruptive but biologically energizing processes (fire, flooding, landslides and erosion), which have also been historically documented for the area for +60 years. This is an early edition of an extensive document by James A. West. Please visit the …

Cseas Weekly Bulletin (November 14, 2011), Center For Southeast Asian Studies

CSEAS Bulletin

No abstract provided.

Oxidative Stress And Heme Oxygenase-1 Regulated Human Mesenchymal Stem Cells Differentiation, Luca Vanella, Christopher Sanford Jr., Dong Hyun Kim, Nader G. Abraham, Nabil Ebraheim

Biochemistry and Microbiology

This paper describes the effect of increased expression of HO-1 protein and increased levels of HO activity on differentiation of bone-marrow-derived human MSCs. MSCs are multipotent cells that proliferate and differentiate into many different cell types including adipocytes and osteoblasts. HO, the rate-limiting enzyme in heme catabolism, plays an important role during MSCs differentiation. HO catalyzes the stereospecific degradation of heme to biliverdin, with the concurrent release of iron and carbon monoxide. Upregulation of HO-1 expression and increased HO activity are essential for MSC growth and differentiation to the osteoblast lineage consistent with the role of HO-1 in hematopoietic stem …

The Science Of Public Health Delivery: Evidence, Uncertainties & Research Needs, Glen P. Mays

Health Management and Policy Presentations

Policy initiatives to reform the nation's health system increasingly recognize the need to incorporate public health and prevention strategies. The nation's delivery system for public health, however, varies widely across states and communities in its structure, authority, and capabilities. This session examines research from the growing field of public health services and systems research to identify directions for improving public health delivery.

Low-Income Seniors More Likely To Develop Heart Failure, Alicia Rohan

Browse All News

No abstract provided.

Crow's Nest, November 14, 2011, Crow's Nest Staff

Crow's Nest

The November 14, 2011, issue of the Crow's Nest.

The Murray State News, November 11, 2011, The Murray State News

Murray State University Collection

No abstract provided.

Reporter - November 11th 2011, Rit Reporter Staff

University Publications

No abstract provided.

Determining The Feasibility Of Implementing A Beekeeping Cooperative In The Bloomington-Normal, Illinois Area, Courtney Luensman '12

Outstanding Senior Seminar Papers

The purpose of this study was to determine the feasibility of implementing a beekeeping cooperative in the Bloomington-Normal, Illinois area. Through the literature review, it is exhibited that honeybees play a very important role in the pollination of certain crops, but there has been a decline in honeybee population, which could result in possible crop reduction. My research was determining benefits and feasibility in the formation of a beekeeping cooperative. Through conducting interviews with beekeepers, farmers, cooperatives, and agricultural organizations, I have determined that there are significant benefits to be gained from the presence of a cooperative, although there are …

Potential Unique Causes Of Burnout For Chiropractic Professionals, Shawn Williams

Publications and Research

Objective The objective of this narrative review is to discuss the potential for burnout in chiropractic practitioners. This discussion is grounded in the job demands-resource model, the conservation of resources model, the unique profession-specific stressors experienced by chiropractors, and information from similar health care professions. Methods A search using both the indexed (PubMed and PsychLit) and nonindexed psychosocial literature was used. Other resources included the Cochrane Library, articles from governing bodies of the chiropractic profession, trade magazines, and research conferences and symposium proceedings. Articles were analyzed following the grounded theory principles: open coding and memos for conceptual labeling, axial coding …

Gsu View, 2011-11-10, Office Of Public Affairs

GSU View

Newsletter published by Governors State University 2007-current.

Accelerate For A Cancer Cure, Staff

Browse All News

No abstract provided.