Digital Commons Network^™

Systemic Aav-Mediated Gene Therapy Using Epo-R76e To Protect Retinal Ganglion Cells From Optic Nerve Injury And Disease, Timothy A. Sullivan

Theses and Dissertations (ETD)

Neuroprotection is a strategy to prevent or reduce neuronal cell death regardless of the underlying cause. Erythropoietin (EPO) exhibits neuroprotective effects in a variety of in vitro and in vivo models of neuronal cell death although its classical function is the regulation of red blood cell production. EPO crosses the blood brain barrier and therefore can be delivered systemically. However, long term treatment with exogenous EPO causes over stimulation of the erythropoietic pathway which can be lethal. The erythropoietic and neuroprotective pathways are regulated by different receptors; further, it is possible to modify EPO to primarily, if not solely, activate …

Effects Of Microgravity On The Growth Kinetics Of Aspergillus Nidulans, Robbyn Chavonne Barnett

Theses (Pre-2016)

N/A

Western Rock Lobster Puerulus Workshop, Department Of Fisheries

Fisheries Occasional Publications

No abstract provided.

Acute Life Threatening Events Associated With Hypocalcemia And Vitamin D Deficiency In Early Infancy. A Single Center Experience From The Kingdom Of Saudi Arabia., Rafat M. Mosalli, Yasser Y. Elsayed, Bosco A. Paes

Saudi Medical Journal

No abstract provided.

Examining Dietary Acculturation In Hispanic Males Residing In South Mississippi, Diana Katherine Cuy Castellanos

Dissertations

This study explored dietary behavior in terms of dietary intake, dietary intake change and dietary contributing factors in a sample of Hispanic males residing in southern Mississippi that are at various stages of the acculturation process. Grounded theory and the bidimensional acculturation model were incorporated to identify the dietary factors and assess acculturation in each participant. Qualitative and quantitative measures were used in data collection. Qualitative measurements included Semistructured interviews, a focus group, and photovoice with group interviews. The ARSMA-II, Marginality Scale, Fruit/Vegetable and Fat Food Screeners, a psychosocial dietary questionnaire, and the New Vital Signs Food Label for Health …

Intergroup Forgiveness In The Middle East: Cognitive And Affective Antecedents To Intergroup Forgiveness And The Relationship Between Intergroup Forgiveness And Psychological Well-Being Among Israeli Jews, Alon Rice

Dissertations

In the past three decades, there has been a burgeoning interest in the scientific study of interpersonal forgiveness. However, only a few studies have elucidated cognitive and affective variables related to intergroup forgiveness. Moreover, no study has examined the degree to which intergroup forgiveness may contribute to one’s psychological well-being, nor has any study thoroughly examined intergroup forgiveness in Israel. Current study results have shown a significant relationship between quality of intergroup contact between Israeli Jews and Israeli Arabs/Palestinians, and Israeli Jews’ forgiveness attitudes toward Palestinians, a relationship mediated by Israeli Jews’ trust, attitudes, and empathy toward Palestinians, as well …

Quantifying And Manipulating Spatiotemporal Trends In Rodent Space Use And Consumption Rates On Incidentally Encountered Prey, Tyler Evan Schartel

Theses

Spatiotemporal heterogeneity in predator activity can generate and influence the availability of refugia to prey. In eastern forests, white-footed mice (Peromyscus leucopus) and eastern chipmunks (Tamias striatus) are abundant generalist rodents, and large-scale removal experiments have confirmed they are important predators of gypsy moth (Lymantria dispar) pupae and songbird nests and eggs. Models predict the extinction of gypsy moth populations when confronted with abundant mouse populations, but small-scale (10s of m) heterogeneity in rodent activity may allow for the persistence of moth populations. I quantified the magnitude, variability, temporal persistence, and spatial structure of white-footed mouse and eastern chipmunk activity, …

The Relationship Between Lower Extremity Bone Mass And Body Mass Index In A Nhanes Adolescent Population, James Randall Post

Theses and Dissertations (ETD)

The effect of body mass index (BMI) on bone mineral content (BMC) among adolescents has been researched yielding mixed results. This study explored the relationship of left lower extremity (LLE) BMC on BMI across the spectrum of weight in a large nationally representative group of adolescents. This descriptive study used secondary data from the publically accessible, cross-sectional survey files of the 1999-2004 Continuous National Health Assessment and Nutritional Examination Survey (NHANES) that contained whole body dual energy X‑ray absorptiometry (DXA) data as well as BMI calculations looking at the adolescent population 12- to19-year-olds at the time of the exam. The …

Perceptions Of Bermudian Leaders About The Philosophies, Major Purposes, And Effectiveness Of The Public School System In Bermuda Since 1987, Vincent Sinclair Williams Jr.

Electronic Theses and Dissertations

This is a study of the perceptions, philosophies, purpose, and effectiveness of public education in Bermuda. It includes a purposeful sample of Bermuda leaders in education, government, business, and public life. I prepared a series of questions that I used as an interview guide to obtain the opinions of participants in the study. Most participants did not provide specific information about the official philosophy, major purposes, or specific educational outcomes of the public education system since its restructuring began in 1987. Many indicated their frustration about the lack of such basic data as enrollment, graduation, and dropout rates. Nearly all …

On The Cranial Osteology Of Eremiascincus And Its Use For Identification., William B. Gelnaw

Electronic Theses and Dissertations

A persistent problem for Australian paleontology has been a lack of diagnostic characters for identifying lizard fossils. Eremiascincus is one of the most widespread genera in Australia, so it was examined for distinguishing features and how it fits into a model of skink evolution. Skulls of Eremiascincus were examined within five separate contexts: 1) a description of the cranial osteology, 2) a qualitative comparison of individual cranial elements of Eremiascincus to closely related Ctenotus, 3) a description of the cranial allometry in Eremiascincus using linear morphometrics, 4) using cranial morphometrics of skinks to deduce their phylogeny, and 5) using …

The Occurrence Of An Abdominal Fauna In An Articulated Tapir (Tapirus Polkensis) Recovered From The Miocene Gray Fossil Site Northeast Tennessee., Shannon M. Mcconnell

Electronic Theses and Dissertations

The analysis of samples recovered from the abdominal area of an articulated tapir from the Late Miocene (4.5-7 million bp) Gray Fossil Site, revealed a rich palyno-fauna comprised of about 94% egg/oocyst-like structures and 6% pollen and other palynomorphs. In addition, a tight grouping of six hickory nuts (Carya) was recovered from the same area suggesting that the samples represent the abdominal contents. The analysis of a sample from immediately outside the tapir produced a sample with 98% pollen and less than 0.5% egg-like structures. The size, shape, and general morphology of egg-like structures were analyzed with light …

Fine Root Responses To Soil Decompaction And Amendment In Red Maple (Acer Rubrum), John Mcintyre

All Theses

A combination treatment (AFM), designed to decompact and amend urban soils, and its individual components (air tillage, fertilizer, and mulch) were tested to determine their effects on fine root morphology. The site was an urban area located in Anderson, SC and included 50 red maples (Acer rubrum) growing in compacted, nutrient poor soils. Treatments were installed in November 2005, and data was collected through summer 2008. Data collection included minirhizotron images, soil moisture readings, soil temperature readings, and pre-dawn leaf water potentials. The AFM treatment had the lowest root production, root standing crop, and median root lifespan. The AFM treatment …

Simultaneous Optimization Of Macronutrient Factors In Plant Tissue Culture Using Turmeric (Curcuma Longa L.) As A Model, Sean Halloran

All Theses

Murashige and Skoog 1962 performed one-factor-at-a-time (OFAT) experimentation in order to regenerate tobacco callus on semi-solid agar medium. This work became an established medium for tissue culture micropropagation and experimentation. Micropropagation is done in niche markets with herbaceous perennials, among other crops, and the optimization of various inputs to produce maximal responses is a necessary step towards process development. This current study of macronutrient factors simultaneously altered media volume, amount of tissue (plants per vessel), sucrose, nitrogen (as NO3- and NH4+ ions), and K+ in a d-optimal design space with only 55 experimental units (including 5 true replicates). The first …

Vitamin A Status In Wheezing Saudi Children., Sherein A. Shalaby, Khaild M. Al-Harbi, Shereen A. El-Tarhouny

Saudi Medical Journal

OBJECTIVES: To examine the serum retinol levels of wheezing children, and to investigate the relation as an biochemical indicator of vitamin A status in wheezing children between serum levels of retinol and severity of wheezing. METHODS: A prospective cohort study including 400 wheezing Saudi children aged 3-36 months, who were treated in the pediatrics ward of Ohoud Public Hospital in Al-Madinah, Kingdom of Saudi Arabia between January 2009 and August 2010. Patients were subdivided according to the course of wheeze into 93 patients with persistent wheeze, and 307 patients with acute wheeze. Severity of wheeze was graded mild, moderate, and …

Applying Grounded Theory To Weight Management Among Women: Making A Commitment To Healthy Eating, Christie Zunker, Nataliya Ivankova

The Qualitative Report

In this study we developed a theory grounded in data from women who continued healthy eating behaviors after a weight management program. Participant recruitment was guided by theoretical sampling strategies for focus groups and individual interviews. Inclusion criteria were: African American or Caucasian women aged 30+ who lost > 5% of their body weight in a weight management program > year ago. Participants > 5% below their baseline weight were maintainers (n = 9); those above were non-maintainers (n = 14). We asked open-ended questions regarding healthy eating behaviors. The systematic design is described in detail, including categories from open coding, connection during …

Stressful Life Events And Behavior Change: A Qualitative Examination Of African American Women's Participation In A Weight Loss Program, Tiffany L. Cox, Christie Zunker, Brooks C. Wingo, Wendy K. Jefferson, Jamy D. Ard

The Qualitative Report

We qualitatively assessed how life stressors affected African American women's participation in a weight reduction program. A sample of 9 women, who completed a behavioral lifestyle intervention, participated in individual, structured, in-depth interviews. Life stressors, ranging from personal illness to changes in employment status, had varied effects on participation. Some women coped with life stressors by using them as a motivational tool to improve their own health, while others reported limited ability to devote time to attend meetings or engage in the prescribed lifestyle changes due to life stressors. A critical key to improving weight loss outcomes for African American …

Trends Over 5 Decades In U.S. Occupation-Related Physical Activity And Their Associations With Obesity, Timothy S. Church, Diana M. Thomas, Catrine Tudor-Locke, Peter T. Katzmarzyk, Conrad P. Earnest, Ruben Q. Rodarte, Corby K. Martin, Steven N. Blair, Claude Bouchard

Faculty Publications

Background: The true causes of the obesity epidemic are not well understood and there are few longitudinal population-based data published examining this issue. The objective of this analysis was to examine trends in occupational physical activity during the past 5 decades and explore how these trends relate to concurrent changes in body weight in the U.S.

Methodology/Principle Findings: Analysis of energy expenditure for occupations in U.S. private industry since 1960 using data from the U.S. Bureau of Labor Statistics. Mean body weight was derived from the U.S. National Health and Nutrition Examination Surveys (NHANES). In the early 1960's almost half …

Characterization Of Potential Health Promoting Lipids In The Co-Products Of De-Flossed Milkweed, Vicki Schlegel, Richard Zbasnik, Tammy Gries, Bo Hyun Lee, Timothy Carr, Ji-Young Lee, Curtis Weller, Susan Cuppett

Department of Agricultural and Biological Systems Engineering: Faculty Publications

The floss and oil of the common milkweed (Asclepias syriaca L.) seeds are currently used to produce comforters/pillows and skin care products, respectively. As an outcome of these products, copious quantities co-products (pressed seed meal and pod biomass) are disposed of each year despite the presence of potential health benefiting lipids. The objective of this project was to determine the feasibility of developing the lipid fraction from of these co-products for the fast growing dietary human health market. Although certain types of lipids were affected by the extraction solvent used (hexane and diethyl ether) as were overall amounts, analysis …

United States Food Law Update: The Fda Food Safety Modernization Act, Obesity And Deceptive Labeling Enforcement, A. Bryan Endres, Nicholas R. Johnson

Journal of Food Law & Policy

The long-awaited enactment of the FDA Food Safety Modernization Act (FSMA), the most significant amendment to the Federal Food, Drug, and Cosmetic Act in several decades, provides the Food and Drug Administration (FDA) with significantly enhanced jurisdiction to close some of the gaps in the domestic food safety system. The enhanced FDA authority, however, will have little impact on the shared governance system at the federal level that involves multiple agencies, as the Act does not address the U.S. General Accounting Office's (GAO) repeated calls for consolidation of the fragmented federal food safety system. Rather, the Act perpetuates the division …

A Descriptive Study Of Dependent And Independent Personality Characteristics Among Psu Singleton And Non-Singleton Students, Jiani Wu

Electronic Theses & Dissertations

This descriptive study was designed to explore, describe, and compare singleton and non-singleton Pittsburg State University Chinese students, who self-reported their independent and dependent personality characteristics. Data for this study were obtained from a survey instrument developed by this investigator and administrated to volunteer Chinese students (Mainland or Taiwan) enrolled in 2010 fall semester at Pittsburg State University. Participation was voluntary and anonymity was assured. No statistically significant differences were found in independent and dependent personality characteristics among singleton and non-singleton Chinese college students at Pittsburg State University. Conclusions were that the findings from the present study were consistent with …

Communication Barriers Between Providers And Parents Of Adhd Adolescent Patients Who Use Complementary And Alternative Medicine, Angela Sietz

Theses and Dissertations

There is increased use of complementary and alternative medicine (CAM) to treat attention deficit hyperactivity disorder (ADHD) symptoms in children and adolescents. Some of the most common types of CAM used in ADHD include: modified diet, vitamins/and or minerals, dietary supplements, aromatherapy and chiropractic care. Many parents/patients do not share their use of CAM with their provider. This inadequate communication between parents and health care providers can be dangerous. This paper addresses the prevalence of ADHD, the types of CAM being used and discusses evidence in support of these therapies. Communication between patients and providers regarding the use of CAM …

Perceived Confirmation And Disconfirmation In Community College Online Distance-Learning Courses, Carissa Michelle Simmons

Communication & Leadership Dissertations and Theses

This qualitative study sought to discover how interpersonal confirmation and disconfirmation are perceived in online distance learning courses at the community college level by determining the specific communication teacher behaviors that cause confirmation and disconfirmation to be perceived by their students. The philosophical framework for this study stemmed from Martin Buber’s (1965) concept of the “interhuman.” The particular theories that grounded this study are the symbolic interactionism theory and two theories of interpersonal confirmation by Sieburg (1973) and Larson (1976). The data for this study was obtained through focus groups, individual interviews, and open-ended surveys. The results show that confirmation …

Potential Benefits From Interacting With Nature: A Look At Outdoor Education For Children, Katie Webster

Psychology and Child Development

With the increase of a fast paced lifestyle and more technology centered activities, children are spending an increased amount of time indoors.  A decreased interaction with the natural environment is alarming to many researchers, including Richard Louv who has defined this lack of interaction as Nature Deficit Disorder, a disorder that may result in a diminished use of the senses, increased amount of attention difficulties and higher rates of physical and emotional illness.  By engaging with nature, children will have the potential of concentrating and performing better within the classroom, to be more creative, are more cognitively and intellectually developed …

Migration Models - Comparison Of Pvc, Pet And Pla Diffusivity, Combined With A Production Cost Model For Westridge Laboratories, Shelley Cooke, Sarina Surrette

Materials Engineering

This project has two parts: [1] a migration and diffusivity model for candidate plastics used in containers, and [2] a product cost model for Westridge Laboratories (Santa Ana, CA).

Diffusion modeling is a useful tool to predict migration of polymer constituents into exposed liquids.  Polyvinyl chloride (PVC), polyethylene terephthalate (PET) and polylactic acid (PLA) were studied to estimate production costs, and component migration into water-based liquids from plastic containers.  Bis (2-ethylhexyl) phthalate (DEHP), antimony trioxide, and stannous octoate, are components of concern in the three candidate polymers, respectively.  Normal detection limits for these constituents are about 1 - 10 ppb, …

St. John’S Wort And Artemisia Extracts Modulate Adipocyte Development And Function, Zhaleh Amini

Honors Capstones

No abstract provided.

Oxidative Derivatization Of Folic Acid Monitored By Capillary Electrophoresis With Uv Absorbance And Fluorescence Detection, Jeffrey P. Cunniff

Honors Capstones

No abstract provided.

The Ability Of Households In Southeast Louisiana Eligible For The Supplemental Nutrition Assistance Program To Meet The Food Recommendations Of The 2010 Dietary Guidelines For Americans, Alicia Rodriguez

Honors Capstones

No abstract provided.

Dental Genetic Traits Of Selected Maya Burials From Wild Cane Cay And Moho Cay, Belize, Kelly Heim

Honors Capstones

No abstract provided.

The Effects Of Curcumin On Body Composition Of Patients With Advanced Pancreatic Cancer, Henrique A. Parsons Md

Dissertations and Theses (Open Access)

Cachexia is very common among patients with advanced pancreatic cancer and is a marker of poor prognosis. Weight loss in cachexia is due to both adipose and muscle compartments, and sarcopenia (severe muscle depletion) is associated with worse outcomes. Curcumin has shown a myriad of biological effects, including anti-cancer and anti-inflammatory. The ability of curcumin to attenuate cachexia and muscle loss has been tested in animal models, with conflicting results so far. The hypothesis of this study was that patients with advanced pancreatic cancer treated with curcumin for two months have less fat and muscle loss as compared to matched …

Immune Modulation Of The Mycobacterium Tuberculosis Granulomatous Response, Kerry J. Welsh

Dissertations and Theses (Open Access)

Tuberculosis (TB) remains a major public health burden. The immunocompetant host responds to Mycobacterium tuberculosis (MTB) infection by the formation of granulomas, which initially prevent uncontrolled bacterial proliferation and dissemination. However, increasing evidence suggests that granuloma formation promotes persistence of the organism by physically separating infected cells from effector lymphocytes and by inducing a state of non-replicating persistence in the bacilli, making them resistant to the action of antibiotics. Additionally, immune-mediated tissue destruction likely facilitates disease transmission. The granulomatous response is in part due to mycobacterial glycolipid antigens. Therefore, studies were first undertaken to determine the innate mechanisms of mycobacterial …