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2011

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Killer Immunoglobulin-Like Receptors And Human Leukocyte Polymorphisms In Hiv-1 Pathogenesis, Aimee Marie Merino Jan 2011

Killer Immunoglobulin-Like Receptors And Human Leukocyte Polymorphisms In Hiv-1 Pathogenesis, Aimee Marie Merino

All ETDs from UAB

Human leukocyte antigen (HLA) molecules influence the adaptive and innate immune responses through interactions with cytotoxic T lymphocytes and natural killer cells (NK). HLA influence the activation state of NK through direct binding to killer immunoglobulin-like receptors (KIR) and presentation of HLA-derived peptides to NKG2 receptors. Activated NK can kill HIV-infected cells through direct cytolysis and release cytokines that influence other aspects of the immune system. Variations in KIR gene content and allelic variants have been associated with autoimmunity, transplantation success, and infectious diseases such as hepatitis C and HIV/AIDS. We investigated the impact of KIR genes and potential KIR-HLA …


Supporting Autonomy In Early Childhood: A Case Study Of Educators Offering Choice, Jann Montgomery Jan 2011

Supporting Autonomy In Early Childhood: A Case Study Of Educators Offering Choice, Jann Montgomery

All ETDs from UAB

The purpose of this study was to explore the behaviors of early childhood educators that support their students' autonomy. Researchers have shown that the most prevalent style of teaching is an autonomy-suppressive style that has been determined to undermine student functioning and achievement (Assor, Kaplan, & Roth, 2002; Reeve, 2009). Teachers are often unaware of the atmosphere they create in their classroom (DeVries & Zan, 1994) and this can result in learning environments that are coercive which has been found to impede children's autonomous thinking (Reeve, 2009). This study sought to explore autonomy-supportive teacher behaviors in the early childhood classroom. …


Firm Size Matters: An Empirical Investigation Of Organizational Size And Ownership On Sustainability- Related Behaviors, Peter Jack Gallo, Lisa Jones Christensen Jan 2011

Firm Size Matters: An Empirical Investigation Of Organizational Size And Ownership On Sustainability- Related Behaviors, Peter Jack Gallo, Lisa Jones Christensen

Faculty Publications

The phrase “corporate sustainability” is increasingly prevalent in both the industry press and management journals (Engardio, 2007; Montiel, 2008). Corporate sustainability pledges and reports are also increasingly prevalent, yet empirical studies on how top managers define and enact the construct are lacking. To address this deficiency, we investigate how firms define, support, and report their sustainability efforts. In a large sample (N = 922) study of accounting executives at U.S.-based firms, we find evidence that organizational size, ownership, and industry are strongly related with support mechanisms and reporting of sustainability.


Video Game Design In The Mba Curriculum: An Experiential Learning Approach For Teaching Design Thinking, James Gaskin, Nicholas Berente Jan 2011

Video Game Design In The Mba Curriculum: An Experiential Learning Approach For Teaching Design Thinking, James Gaskin, Nicholas Berente

Faculty Publications

In the spirit of design thinking, we have developed a ―hands-on‖ video game design workshop intended to be used for an MBA course on design thinking. This novel approach to teaching complex concepts and skills to business students has been received with enthusiasm, and it provides a unique and memorable experience for students to draw on as they encounter situations in which they will apply design thinking in the future. Additionally, student-produced games and student reflections on the workshops provide initial evidence of the value of teaching design thinking through this type of experiential method. In this article we review …


Modeling Incident And Emergency Management From A Regional Perspective, Ozge Cavusoglu Jan 2011

Modeling Incident And Emergency Management From A Regional Perspective, Ozge Cavusoglu

All ETDs from UAB

Traffic incidents and natural or man-made disasters can impose significant safety risks and disruptions on traffic flows, often resulting in non-recurring congestion. Congestion, in turn, may impede the ability of EMS (Emergency Medical Services) to provide timely response to those in need of medical attention. Thus, it is important to understand the potential impacts of incidents and emergencies on traffic network operations and develop response strategies with a potential of minimizing such impacts on traffic operations, emergency response and the safety of the traveling public. The objective of the dissertation was twofold: a. Study incident management options and benefits from …


Structural And Mechanistic Studies On Er Upr Sensor Perk And Mitochondrial Translocon Element Tim44, Wenjun Cui Jan 2011

Structural And Mechanistic Studies On Er Upr Sensor Perk And Mitochondrial Translocon Element Tim44, Wenjun Cui

All ETDs from UAB

The unfolded protein response is one mechanism utilized by endoplasmic reticulum (ER) to maintain the homeostasis between ER protein folding machinery and ER proteins. UPR is induced by three ER transmembrane sensors: IRE1, ATF6 and PERK. PKR-like ER kinase (PERK) can sense the ER stress signal through its luminal domain to activate its cytoplasmic kinase domain catalytic activity. PERK kinase domain belongs to the eIF2α family. Members in this family are activated after being autophosphorylated at their activation loops and then specifically phosphorylate eIF2α at its Ser51 position. Phosphorylation of eIF2α can shutdown the cytosol protein translation from the initiation …


Academic Advising And Retention Of First-Generation College Students At A Research University In The Southeast, Hadyn K. Swecker Jan 2011

Academic Advising And Retention Of First-Generation College Students At A Research University In The Southeast, Hadyn K. Swecker

All ETDs from UAB

Student retention is an area of concern both academically and financially for higher education institutions. With the state of the current economy, finances are a critical component to higher education institutions. Retention rates, in addition to graduation rates, are used for assessing the overall success of an institution and in some instances future funding. According to Schneider (2010), only 60% of undergraduate students matriculate from four-year institutions within six years of initial enrollment. One population, first-generation college students, are 1.3 times more likely than their non-first-generation peers to leave an institution during their first year of college (Ishitani, 2006). The …


Effects Of Estrogen On Hippocampal Function In Young Adult And Aged Female Rats, Lindsey Celeste Vedder Jan 2011

Effects Of Estrogen On Hippocampal Function In Young Adult And Aged Female Rats, Lindsey Celeste Vedder

All ETDs from UAB

In rodents, the ovarian estrogen 17b-estradiol (E2) is a potent modulator of hippocampal function and the hippocampus is critical for many types of learning and memory. Specifically, E2 increase the magnitude of long-term potentiation (LTP) at CA3-CA1 synapses, the density of dendritic spines in CA1 pyramidal cells and current mediated by NR2B-containing NMDA receptors. The E2-induced increase in LTP further requires NR2B-containing NMDARs. While considered a cellular correlate of learning and memory, enhanced LTP does not always predict enhanced learning. The first goal of this dissertation was to investigate the relationship between E2-enhanced LTP and learning and memory in young …


Role Of Nr4a3 Nuclear Receptor In Physiological Regulation Of Metabolism, Grace R. Walton Jan 2011

Role Of Nr4a3 Nuclear Receptor In Physiological Regulation Of Metabolism, Grace R. Walton

All ETDs from UAB

Nuclear receptor NR4A3 (NOR-1, MINOR) mediates transcriptional responses to ß-adrenergic signaling, is increased in insulin sensitive mice and humans, and enhances insulin-stimulated glucose transport in cultured adipocytes and myocytes. We therefore sought to determine the role of NR4A3 in in vivo adipose tissue and skeletal muscle physiology. Following adipose-specific NR4A3 over-expression in mice, we observed reduced circulating epinephrine due to enhanced catabolism of catecholamines in adipose tissue. Furthermore, this reduction in circulating epinephrine produced broad physiological consequences, including poor glucose tolerance, reduced insulin sensitivity, dyslipidemia, poor cardiac function, and behavioral alterations. In skeletal muscle, we show that NR4A3 protein associates …


Strategies For Combined Screening And Imaging Of Breast Cancer, Jason Morgan Warram Jan 2011

Strategies For Combined Screening And Imaging Of Breast Cancer, Jason Morgan Warram

All ETDs from UAB

Successful treatment of breast cancer directly correlates with tumor stage and grade at diagnosis. Early diagnosis leads to a five-year relative survival rate of 96.8% as opposed to only a 22.5% five-year survival rate when diagnosed at late stage. Cancer-specific mechanisms need to be extended to enable cancer detection in an individual patient, in particular, the metastatic burden that currently cannot be assessed by conventional imaging. This approach for cancer detection would remove the biases of patient characteristics, permit immediate diagnostic feedback, improve sensitivity for early detection of small metastatic lesions, and be cost effective. Toward this goal, the cancer-specific …


Sustainable Urban Design Practices That Mitigate Urban Heat Islands And Reduce Energy Consumption, Candace Joy Watson Jan 2011

Sustainable Urban Design Practices That Mitigate Urban Heat Islands And Reduce Energy Consumption, Candace Joy Watson

All ETDs from UAB

Urban cities are the largest consumers of energy. As global populations continue to increase in these areas, energy consumption is a growing concern for global leaders. Cities in developed countries are expanding beyond their central city-centers, resulting in increased natural resource consumption. This method of population management is referred to as urban sprawl and is the reason for increased consumption from expanding transportation networks, building materials, and fuel resources. In addition to increases in energy consumption, in recent years, built-up areas have experienced higher temperatures than surrounding rural areas. According to the Environmental Protection Agency, these differences can be as …


Ecology And Transmission Of Eastern Equine Encephalitis Virus In The Southeastern United States, Gregory Scott White Jan 2011

Ecology And Transmission Of Eastern Equine Encephalitis Virus In The Southeastern United States, Gregory Scott White

All ETDs from UAB

The virus Eastern Equine Encephalitis virus (EEEV) is a highly pathogenic arthropod-borne virus (arbovirus) present in the US. The virus is listed as a reportable illness to the Centers of Disease Control and Prevention (CDC) and is also listed as a select agent by Human Health and Services (HHS). Studies on EEEV starting back in the 1930's have determined many important facets of the ecology, transmission and evolution of the virus. It is understood that in many endemic foci, the mosquito Culiseta melanura is the primary enzootic vector of the virus. EEEV is thus maintained in an enzootic cycle between …


Conceptualization Of Cervical Cancer And Screening Experiences Among Zambian Women Attending A Cervical Screening Program, Heather Leah White Jan 2011

Conceptualization Of Cervical Cancer And Screening Experiences Among Zambian Women Attending A Cervical Screening Program, Heather Leah White

All ETDs from UAB

Invasive cervical cancer (ICC) is the second most commonly diagnosed malignancy worldwide, and approximately 85% of the disease burden occurs in underdeveloped countries. In 2006, the Zambian government launched a cervical screening program within primary health clinics using visual inspection with acetic acid (VIA) coupled with immediate treatment via cryotherapy. The objective of this dissertation was to determine whether the VIA screening program is responsive to the needs and concerns of Zambian women in an effort to improve screening uptake, and for human immunodeficiency virus (HIV) positive women who are potentially subject to increased ICC screening and treatment, increase long-term …


Functional Interplay Between Trans Factors And Cis-Elements That Govern Il17a&F Transcription, Sarah Kern Whitley Jan 2011

Functional Interplay Between Trans Factors And Cis-Elements That Govern Il17a&F Transcription, Sarah Kern Whitley

All ETDs from UAB

Protective immunity against a variety of infections depends on the amplification and differentiation of naïve antigen-specific CD4 T cells. T helper 17 (Th17) cells are important for defending mucosal barriers from invading extracellular bacterial pathogens. This effector CD4 lineage is characterized by production of the cytokines IL-17A, IL-17F, IL-21, and IL-22, which elicit influx of inflammatory cells to promote pathogen clearance. The cytokines IL-6 and TGF&beta are the principal factors that initiate Th17 lineage development, and the STAT3-inducing cytokines IL-21 and IL-23 assist and/or maintain the Th17 developmental program. Recently, an additional cytokine has been demonstrated to encourage Th17 differentiation: …


Pick It Up, Put It Down: A Grounded Theory Study Of How Low Income African American Patients In The Deep South Start Smoking And Quit Smoking, Jessica Hillman Williams Jan 2011

Pick It Up, Put It Down: A Grounded Theory Study Of How Low Income African American Patients In The Deep South Start Smoking And Quit Smoking, Jessica Hillman Williams

All ETDs from UAB

The purpose of this qualitative was to use data extracted from the narrative stories of African American patients to generate a grounded theory to explain the process and act of initiating and of quitting smoking among low income African American patients in the Deep South. This is important since African Americans are more likely to suffer from smoking-related illnesses, which are the leading cause of death among African Americans. Data were analyzed from interviews conducted in 2005 as part of the Stories Project and supplementary interviews conducted in 2011. Convenience sampling strategies guided participant recruitment for primary interviews and theoretical …


Tear Component Interference In Bead-Based Biomarker Assays Using Magnetic Beads, Larezia Denise Williams Jan 2011

Tear Component Interference In Bead-Based Biomarker Assays Using Magnetic Beads, Larezia Denise Williams

All ETDs from UAB

Cytokines in tears can be biomarkers for ocular inflammation in dry eye subjects. Multiplex bead-based assays measure the concentration of multiple cytokines in a single tear sample. Bio-Rad® polystyrene bead-based assay kits have provided acceptable results for tear samples in this lab. Recently, Bio-Rad decided to replace polystyrene beads with magnetic beads. In earlier experiments in this laboratory, magnetic bead-based as-says did not produce results equivalent to polystyrene bead-based assays. The purpose of this investigation was to modify the magnetic bead-based tear cytokine assay to produce equivalent results to those obtained with the polystyrene bead-based assay. The modifications included running …


Measuring Aniseikonia Using Scattering Filters To Simulate Cataract, Jason Anthony Wilson Jan 2011

Measuring Aniseikonia Using Scattering Filters To Simulate Cataract, Jason Anthony Wilson

All ETDs from UAB

MEASURING ANISEIKONIA USING SCATTERING FILTERS TO SIMULATE CATARACT JASON WILSON DEPARTMENT OF VISION SCIENCE ABSTRACT The relationship between anisometropia and aniseikonia (ANK) is not well understood. Ametropic cataract patients provide a unique opportunity to study this relationship after undergoing emmetropizing lens extraction. Because light scatter may affect ANK measurement in cataract patients, its effect should also be evaluated. The Basic Aniseikonia Test (BAT) was evaluated using afocal size lenses to produce specific changes in retinal height. Several light scattering devices were then evaluated to determine which produced effects most similar to cataract. Contrast sensitivity and visual acuity (VA) losses were …


Enamel Demineralization Around Bonded Orthdontic Appliances Using Resin Coatings, Michael Brett Wood Jan 2011

Enamel Demineralization Around Bonded Orthdontic Appliances Using Resin Coatings, Michael Brett Wood

All ETDs from UAB

Introduction: Orthodontists work to achieve a favorable esthetic and functional result, only to have the outcome tainted by the presence of demineralization upon appliance removal. The presence of WSL's is a disappointment to both orthodontists and patients. Several products have been developed to prevent this unfortunate damage to tooth structure, including "Opalseal" and "Ortho-coat". Opalseal is a 38% filled primer that releases and recharges fluoride. Ortho-coat is a fluoride releasing, light cure, hydrophilic resin that coats both the bracket and tooth surface preventing decalcification. The aim of this study was to investigate the barrier effect of Opalseal and Ortho-coat compared …


Regulation Of Neuronal Death By The Autophagy Lysosomal Pathway: Implications For Parkinson Disease, Violetta N. Pivtoraiko Jan 2011

Regulation Of Neuronal Death By The Autophagy Lysosomal Pathway: Implications For Parkinson Disease, Violetta N. Pivtoraiko

All ETDs from UAB

Parkinson Disease (PD) is the second most common age-related neurodegenerative disorder and is characterized pathologically by the loss of dopaminergic (DA) neurons in the stubstantia nigra pars compacta (SNpc). Mitochondrial dysfunction, increased oxidative stress, and accumulation of aggregated α-synuclein (α-syn), an intracellular protein involved in synaptic function, are all pathological hallmarks of PD have been implicated in PD pathogenesis. However, it is debated whether α-syn aggregates themselves are responsible for neurodegeneration in PD, cellular pathways involved in degradation of α-syn aggregates are believed to promote neuron survival. The autophagy lysosomal pathway (ALP), a physiological mechanism for recycling of intracellular components, …


Examination Of Ideal Physical Parameter Choices For Efficacious Hyperthermic Treatment Of Cancer, Lauren Rast Jan 2011

Examination Of Ideal Physical Parameter Choices For Efficacious Hyperthermic Treatment Of Cancer, Lauren Rast

All ETDs from UAB

This dissertation presents results on the computational modeling of electromagnetic and thermal effects during the hyperthermic treatment of cancer using magnetic nanoparticles. Magnetic nanoparticle hyperthermia can be used for direct targeting and destruction of tumors through heat treatment or as a complement to chemotherapy. This method of treatment would be much less invasive than many current treatment options. Additionally, since these are nanoscale devices, the hyperthermic treatment of the cancer cells would be extremely localized. This would cause very minimal damage to surrounding tissue, making these systems superior to traditional hyperthermic treatment. The use of ferrofluids for cancer treatment requires …


Myosin Ii In Hippocampal Synapses: Regulation Of Synaptic Plasticity, Strength And Actin Dynamics By Two Distinct Isoforms, Maria Dolores Rubio Jan 2011

Myosin Ii In Hippocampal Synapses: Regulation Of Synaptic Plasticity, Strength And Actin Dynamics By Two Distinct Isoforms, Maria Dolores Rubio

All ETDs from UAB

Cytoskeletal actin filaments underlie dendritic spine plasticity, critical for several forms of learning and memory. Therefore, understanding the mechanisms that regulate actin dynamics is essential to elucidate memory formation pathways. Myosins, a superfamily of actin binding proteins, have emerged as candidates for regulation of actin dynamics in the brain. Several myosin class II isoforms have been identified in brain, but their individual contribution to synaptic activity is still unknown. Based on the finding that myosin IIB regulates actin polymerization in the growth cone of developing neurons and that it is necessary for maintenance of dendritic spine structure, I hypothesized that …


The Natural History Of Sivcpz Infection In Wild Living Chimpanzees, Rebecca Steele Rudicell Jan 2011

The Natural History Of Sivcpz Infection In Wild Living Chimpanzees, Rebecca Steele Rudicell

All ETDs from UAB

Simian immunodeficiency virus of chimpanzees (SIVcpz) is the immediate precursor to human immunodeficiency virus type 1 (HIV-1), but even the most basic aspects of SIVcpz infection in its natural host are unknown. Here, we present the first comprehensive analysis of the natural history of SIVcpz infection in wild living chimpanzees. Using non-invasive (feces and urine based) methods, we studied two unique chimpanzee populations in Tanzania: the famous chimpanzees of Gombe National Park and the savanna chimpanzees of Ugalla, located about 135 km southeast of Gombe. Gombe chimpanzees are endemically infected with SIVcpz, and the park's established research infrastructure provides a …


Increased Cutting Efficacy Of Diamond Burs With Biochemical Solution Spraying, Ramtin Sadid Zadeh Jan 2011

Increased Cutting Efficacy Of Diamond Burs With Biochemical Solution Spraying, Ramtin Sadid Zadeh

All ETDs from UAB

CAD/CAM units are becoming increasingly popular for milling all ceramic restorations from ceramic blocks. The solution used to spray the diamond cutting instrument also improves cutting effectiveness and also lubricates the diamond, which may not only prolong the cutting life of the diamond instrument but also provide smoother cuts on the ceramic block. The purpose of this study is to evaluate cutting efficacy of diamond burs with three solutions and to compare roughness produced by each solution on the glass-ceramic block. Material and methods: 15 Empress CAD blocks, 30 fine diamond burs, two solutions and distilled water were used. Each …


Human Cytosolic Sulfotransferase 2b1b: Structure, Function And Expression In Human Brain, Emily D. Salman Jan 2011

Human Cytosolic Sulfotransferase 2b1b: Structure, Function And Expression In Human Brain, Emily D. Salman

All ETDs from UAB

The human cytosolic sulfotransferases are a family of phase II drug-metabolizing enzymes that conjugate a sulfonate moiety from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to a hydroxyl moeity on a substrate. SULT2B1b catalyzes the sulfation of hydroxysteroids as well as many xenobiotics; and is expressed extra-hepatically. SULT2B1b is a unique SULT because it has amino (N)- and carboxy (C)-terminal peptide extensions, undergoes post-translational modification, and is localized in both the cytosol and nucleus. Analysis of SULT2B1b revealed that the N- and C-terminal extensions of SULT2B1b are predicted to be intrinsically unstructured peptides. Size exclusion chromatography has revealed that SULT2B1b is enzymatically active as …


Optimization And Characterization Of Bioactive Glass Nanofibers And Nanocomposites, Reginna Evette Scarber Jan 2011

Optimization And Characterization Of Bioactive Glass Nanofibers And Nanocomposites, Reginna Evette Scarber

All ETDs from UAB

Disease affects different areas of the bone and can impact individuals of all pathologies and ethnicities. These bone diseases can result in weakening which leads to trauma during ordinary function, the need for reconstructive surgery, and eventual bone replacement. Tissue engineering can provide a less traumatic and more fundamental solution to the current therapies. Bioactive glasses are promising materials in tissue engineering applications because of their ability to form hydroxycarbonate apatite in the presence of simulated body fluid, support cell adhesion, growth, and differentiation, induce bone formation, and concentrate bone morphogenic proteins in vivo. The research in this dissertation will …


Thesis- Clinical Evaluation Of Non-Carious Cervical Lesion- A Longitudinal Study., Shreya D. Shah Jan 2011

Thesis- Clinical Evaluation Of Non-Carious Cervical Lesion- A Longitudinal Study., Shreya D. Shah

All ETDs from UAB

Non-carious cervical lesions (NCCL) are non-bacterial in origin and defined as the loss of tooth substance at the cemento-enamel junction (Mair, 1992). There is growing evidence that NCCLs may be associated with occlusal and lateral. OBJECTIVE: To develop a non invasive, highly reproducible technique to measure the occlusal forces (biting pressure) and to correlate it with lesion progression. MATERIALS & METHODS: Twenty-six subjects and 60 teeth were measured for biting force. Digital images and elastomeric impressions were made ateach of three visits (baseline restoration, one and two years). Casts were prepared and a fixture which aligned each patients cast in …


Effect Of Different Percentages Of Silica Nanofibers Filler Loads On Mechanical And Physical Properties Of Flowable Composite Resins, Shashikant Singhal Jan 2011

Effect Of Different Percentages Of Silica Nanofibers Filler Loads On Mechanical And Physical Properties Of Flowable Composite Resins, Shashikant Singhal

All ETDs from UAB

Dental composites are important in the spectra of restorative materials. Ability to match the color of natural dentition is an appealing characteristic of composite restorations. Additionally, they can be bonded physically to the tooth, which limits the amount of tooth preparation required and thereby conserves healthy tooth structure. In relation to other restorations like amalgams, non-metallic compositions of dental composites have exhibited good biocompatibility. The dental composites are composed of a resin matrix containing a blend of bis-GMA (bis-phenol A-glycidyldimethacrylate) or urethane dimethacrylate (UDMA) along with TEGDMA (tetraethylglycidylmethacrylate). Novel techniques for the reinforcement of these resin-based composites continue in a …


Social Support, Social Stigma, Health, Coping, And Quality Of Life In Older Gay Men With Hiv, Larry Zuendel Slater Jan 2011

Social Support, Social Stigma, Health, Coping, And Quality Of Life In Older Gay Men With Hiv, Larry Zuendel Slater

All ETDs from UAB

With the advent of antiretroviral therapy, people with HIV/AIDS are living longer and managing their HIV infection as would an individual with any other chronic disease. As life expectancy increases, quality of life has progressed as an emerging issue for older adults with HIV/AIDS. A majority of people living with HIV in the U.S. are still gay men, who thus comprise a large portion of those who are growing older with the disease. The aims of the descriptive, correlational study were to: (1) explore the relationships among age, race, socioeconomic status, health, social support, social stigma, coping, perceived health, and …


The Effect Of Curricular Sequencing Of Human Patient Simulation Learning Experiences On Students’ Self-Perceptions Of Clinical Reasoning Abilities, Rebecca Jensen Phd, Rn Jan 2011

The Effect Of Curricular Sequencing Of Human Patient Simulation Learning Experiences On Students’ Self-Perceptions Of Clinical Reasoning Abilities, Rebecca Jensen Phd, Rn

Nursing Publications, Posters, & Presentations

It is unknown whether timing of human patient simulation (HPS) in a semester, demographic (age, gender, and ethnicity), and situational (type of program and previous baccalaureate degree and experience in healthcare) variables affects students‘ perceptions of their clinical reasoning abilities. Nursing students were divided into two groups, mid and end of semester HPS experiences. Students‘ perceptions of clinical reasoning abilities were measured at Baseline (beginning of semester) and Time 2 (end of semester), along with demographic and situational variables. Dependent variable was Difference scores where Baseline scores were subtracted from Time 2 scores to reveal changes in students‘ perceptions of …


Predictors Of The Decision To Terminate Pregnancy Following Prenatal Diagnoses Of Fetal Abnormalities, Cynthia Renee Hall Jan 2011

Predictors Of The Decision To Terminate Pregnancy Following Prenatal Diagnoses Of Fetal Abnormalities, Cynthia Renee Hall

All ETDs from UAB

The purpose of the present study was to examine several factors and their contri-butions to termination decisions and address limitations associated with previous re-search. Specifically, type of prenatally diagnosed disorder, perception of parenting, atti-tude toward abortion, attachment, religiosity, and attitude toward disabled persons were examined as predictors of the decision to terminate pregnancy. Also, the role of familiari-ty with persons having developmental disabilities was explored as a covariate. In addi-tion, priming effect of labeled disorders was investigated. Participants (N = 144) were college students aged 19 - 56 years (M = 22.07, SD = 6.62). Participants completed the Experiences in …