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Surface Complexation Modeling For Predicting Solid Phase Arsenic Concentrations In The Sediments Of The Mississippi River Valley Alluvial Aquifer, Arkansas, Usa, Md. Salah U. Sharif, Ralph K. Davis, Kenneth F. Steele, Burmshik Kim, Phillip D. Hays, Tim M. Kresse, John A. Fazio

United States Geological Survey: Staff Publications

The potential health impact of As in drinking water supply systems in the Mississippi River Valley alluvial aquifer in the state of Arkansas, USA is significant. In this context it is important to understand the occurrence, distribution and mobilization of As in the Mississippi River Valley alluvial aquifer. Application of surface complexation models (SCMs) to predict the sorption behavior of As and hydrous Fe oxides (HFO) in the laboratory has increased in the last decade. However, the application of SCMs to predict the sorption of As in natural sediments has not often been reported, and such applications are greatly constrained …

Mercury Trends In Fish From Rivers And Lakes In The United States, 1969–2005, Ann Chalmers, Denise M. Argue, David A. Gay, Mark E. Brigham, Christopher J. Schmitt, David Lorenz

United States Geological Survey: Staff Publications

A national dataset on concentrations of mercury in fish, compiled mainly from state and federal monitoring programs, was used to evaluate trends in mercury (Hg) in fish from US rivers and lakes. Trends were analyzed on data aggregated by site and by state, using samples of the same fish species and tissue type, and using fish of similar lengths. Site-based trends were evaluated from 1969 to 2005, but focused on a subset of the data from 1969 to 1987. Data aggregated by state were used to evaluate trends in fish Hg concentrations from 1988 to 2005. In addition, the most …

A Geospatial Approach To Identify Water Quality Issues For National Wildlife Refuges In Oregon And Washington, Jo Ellen Hinck, Kimberly Chojnacki, Susan Finger, Greg Linder, Kevin Kilbride

United States Geological Survey: Staff Publications

Many National Wildlife Refuges (Refuges) have impaired water quality resulting from historic and current land uses, upstream sources, and aerial pollutant deposition. Competing duties limit the time available for Refuge staff to identify and evaluate potential water quality issues. As a result, water quality–related issues may not be resolved until a problem has already arisen. This study developed a geospatial approach for identifying and prioritizing water quality issues affecting natural resources (including migratory birds and federally listed species) within Refuge boundaries. We assessed the location and status of streams pursuant to the Clean Water Act in relation to individual Refuges …

Smooth Brome (Bromus Inermis Leyss) And Soil Chemical Response To Concrete Grinding Residue Application, Tom Desutter, Patricia Goosen-Alix, Lyle Prunty, Paul White Jr., Frank Casey

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Concrete grinding residue (CGR) is a byproduct created by concrete pavement maintenance operations. The application of CGR to roadside soils is not consistently regulated by state agencies across the USA, which is partially due to the lack of science-based information on its impacts to soils and plants. The objectives of this research were to determine the impact of CGR additions to soil on both smooth brome (Bromus inermis L.) biomass and plant and soil chemical parameters. In a greenhouse study, two soils were treated with two CGR by-products at 8% and 25% by weight. Shoot biomass was significantly influenced …

Susceptibility Of Selected Potato Varieties To Zebra Chip Potato Disease, Joseph E. Munyaneza, Jeremy L. Buchman, Venkatesan G. Sengoda, Tonja W. Fisher, Cole C. Pearson

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Zebra chip (ZC), an emerging and serious disease of potato has caused millions of dollars in losses to the potato industry in the United States, Mexico, Central America, and New Zealand. The disease has recently been associated with a previously undescribed species of liberibacter tentatively named “Candidatus Liberibacter solanacearum” transmitted to potato by the potato psyllid, Bactericera cockerelli (Šulc). At present, applications of insecticides targeted against the potato psyllid are the only means to manage ZC. Given the low psyllid density and short inoculation access period required to induce the disease, insecticides may not act fast enough to prevent …

Challenges Of Predicting The Potential Distribution Of A Slow-Spreading Invader: A Habitat Suitability Map For An Invasive Riparian Tree, Catherine S. Jarnevich, Lindsay V. Reynolds

United States Geological Survey: Staff Publications

Understanding the potential spread of invasive species is essential for land managers to prevent their establishment and restore impacted habitat. Habitat suitability modeling provides a tool for researchers and managers to understand the potential extent of invasive species spread. Our goal was to use habitat suitability modeling to map potential habitat of the riparian plant invader, Russian olive (Elaeagnus angustifolia). Russian olive has invaded riparian habitat across North America and is continuing to expand its range. We compiled 11 disparate datasets for Russian olive presence locations (n = 1,051 points and 139 polygons) in the western US and …

Evaluating The Effect Of Predators On White-Tailed Deer: Movement And Diet Of Coyotes, Melissa M. Turner, Aimee P. Rockhill, Christopher S. Deperno, Jonathan A. Jenks, Robert W. Klaver, Angela R. Jarding, Troy W. Grovenburg, Kenneth H. Pollock

United States Geological Survey: Staff Publications

Coyotes (Canis latrans) may affect adult and neonate white-tailed deer (Odocoileus virginianus) survival and have been implicated as a contributor to the decline of deer populations. Additionally, coyote diet composition is influenced by prey availability, season, and region. Because coyote movement and diet vary by region, local data are important to understand coyote population dynamics and their impact on prey species. In southeast Minnesota, we investigated the effect of coyotes on white-tailed deer populations by documenting movement rates, distances moved, and habitats searched by coyotes during fawning and nonfawning periods. Additionally, we determined survival, cause-specific mortality, …

Introduction To “Environmental Contaminants In Biota, 2nd Edition”, W. Nelson Beyer, James P. Meador

United States Geological Survey: Staff Publications

Ecotoxicology is the study of the movement of environmental contaminants through ecosystems and their effects on plants and animals. Examining tissue residues of these contaminants in biota is basic to ecotoxicology, both for understanding the movement of contaminants within organisms and through food chains, and for understanding and quantifying injuries to organisms and their communities. This book provides guidance on interpreting tissue concentrations of environmental contaminants.

Tissue concentrations have long been used both to identify the cause of toxicity in animals and as a measure of the severity of toxicity. More recently, they have been incorporated into environmental models, tying …

Lead In Birds, J. Christian Franson, Deborah J. Pain

United States Geological Survey: Staff Publications

Lead is a highly toxic heavy metal that acts as a nonspecific poison affecting all body systems and has no known biological requirement. Absorption of low concentrations may result in a wide range of sublethal effects in animals, and higher concentrations may result in mortality (Demayo et al. 1982).

Lead has been mined and smelted by humans for centuries, but the use of lead-based products increased greatly following the Industrial Revolution. Consequently, lead today is ubiquitous in air, water, and soil, in both urban and rural environments (Eisler 2000). Vertebrates are exposed to lead mainly via inhalation and ingestion. A …

Correlation Of Omega-3 Fatty Acids Intakes With Acculturation And Socioeconomic Status In Midwestern Latinas, Karina R. Lora, Nancy M. Lewis, Kent M. Eskridge, Kaye Stanek-Krogstrand, Daryl A. Travnicek

Department of Nutrition and Health Sciences: Faculty Publications

Background: Low socioeconomic status (SES) and acculturation of Latino immigrants in the U.S. are linked to a decrease in diet quality. Methods: Interviews were conducted with 162 first-generation Latinas to examine the association of SES and acculturation with intake of omega-3 (n − 3) fatty acids. Each participant provided dietary intake by use of a validated n − 3 food frequency questionnaire administered twice, 4 weeks apart, three 24-h recalls, sociodemographic information and completed the 5-item Short Acculturation Scale. Results: Mean intakes of Total n − 3, α-linolenic acid (ALA), eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) (g/d) were …

The Role Of Histone H4 Biotinylation In The Structure Of Nucleosomes, Nina A. Filenko, Carol Kolar, John T. West, S. Abbie Smith, Yousef I. Hassan, Gloria E. O. Borgstahl, Janos Zempleni, Yuri L. Lyubchenko

Department of Nutrition and Health Sciences: Faculty Publications

Background: Post-translational modifications of histones play important roles in regulating nucleosome structure and gene transcription. It has been shown that biotinylation of histone H4 at lysine-12 in histone H4 (K12Bio-H4) is associated with repression of a number of genes. We hypothesized that biotinylation modifies the physical structure of nucleosomes, and that biotin-induced conformational changes contribute to gene silencing associated with histone biotinylation.

Methodology/Principal Findings: To test this hypothesis we used atomic force microscopy to directly analyze structures of nucleosomes formed with biotin-modified and non-modified H4. The analysis of the AFM images revealed a 13% increase in the length of …

Body Mass Index Is Associated With Dietary Patterns And Health Conditions In Georgia Centenarians, Dorothy B. Hausman, Mary Ann Johnson, Adam Davey, Leonard W. Poon

Department of Nutrition and Health Sciences: Faculty Publications

Associations between body mass index (BMI) and dietary patterns and health conditions were explored in a population-based multiethnic sample of centenarians from northern Georgia. BMI ≤20 and ≥25 was prevalent in 30.9% and 25.3% of study participants, respectively. In a series of logistic regression analyses controlled for gender and place of residence, the probability of having BMI ≥25 was increased by being black versus white and having a low citrus fruit, noncitrus fruit, orange/yellow vegetable or total fruit and vegetable intake. The probability of having BMI ≤20 was not associated with dietary intake. When controlled for race, gender, residence, and …

A Field Evaluation Of A Trap For Invasive American Bullfrogs, Nathan P. Snow, Gary W. Witmer

United States Department of Agriculture Wildlife Services: Staff Publications

Native to the eastern United States, American bullfrogs (Rana catesbeiana [Lithobates catesbeianus]) have been introduced in many countries throughout the world. There have been relatively few effective and efficient control methods developed to manage bullfrogs. Particularly in the Hawaiian Islands, Pacific coast of North America, and Japan, finding effective methods for controlling invasive bullfrogs is needed with special emphasis on low impacts for sensitive native species. We conducted a field study to examine the efficacy of a newly designed live trap for capturing invasive bullfrogs. We found that our trap was successful at capturing bullfrogs because we …

Adaptive Resource Management And The Value Of Information, Byron K. Williams, Mitchell J. Eaton, David R. Breininger

United States Geological Survey: Staff Publications

The value of information is a general and broadly applicable concept that has been used for several decades to aid in making decisions in the face of uncertainty. Yet there are relatively few examples of its use in ecology and natural resources management, and almost none that are framed in terms of the future impacts of management decisions. In this paper we discuss the value of information in a context of adaptive management, in which actions are taken sequentially over a timeframe and both future resource conditions and residual uncertainties about resource responses are taken into account. Our objective is …

Population Health Metrics Research Consortium Gold Standard Verbal Autopsy Validation Study: Design, Implementation, And Development Of Analysis Datasets, C.J.L. Murray, A.D. Lopez, R. Black, R. Ahuja, S.M. Ali, A. Baqui, L. Dandona, E. Dantzer, Vinita Das, U. Dhingra, A. Dutta, W. Fawzi, A.D. Flaxman, S. Gomez, B. Hernandez, R. Joshi, H. Kalter, A. Kumar, V. Kumar, R. Lozano, M. Lucero, S. Mehta, B. Neal, S.L. Ohno, R. Prasad, D. Praveen, Zul Premji, D. Ramirez-Villalobos, H. Remolador, I. Riley, M. Romero, M. Said, D. Sanvictores

Pathology, East Africa

Background: Verbal autopsy methods are critically important for evaluating the leading causes of death in populations without adequate vital registration systems. With a myriad of analytical and data collection approaches, it is essential to create a high quality validation dataset from different populations to evaluate comparative method performance and make recommendations for future verbal autopsy implementation. This study was undertaken to compile a set of strictly defined gold standard deaths for which verbal autopsies were collected to validate the accuracy of different methods of verbal autopsy cause of death assignment.

Methods: Data collection was implemented in six sites in four …

Poverty Tourism And The Problem Of Consent, Kyle Powys Whyte, Evan Selinger, Kevin Outterson

Faculty Scholarship

Is it morally permissible for financially privileged tourists to visit places for the purpose of experiencing where poor people live, work, and play? Tourism associated with this question is commonly referred to as 'poverty tourism.' While some poverty tourism is plausibly ethical, other practices will be more controversial. The purpose of this essay is to address mutually beneficial cases of poverty tourism and advance the following positions. First, even mutually beneficial transactions between tourists and residents in poverty tourism always run a risk of being exploitative. Second, there is little opportunity to determine whether a given tour is exploitative since …

Religious And Political Virtues And Values In Congruence Or Conflict?: On Smith, Bob Jones University, And Christian Legal Society, Linda C. Mcclain

Faculty Scholarship

A basic tension in the U.S. constitutional and political order exists between two important ideas about the relationship between civil society and the state: (1) families, religious institutions, voluntary associations, and other groups are foundational sources, or “seedbeds,” of virtues and values that undergird constitutional democracy, and (2) these same institutions guard against governmental orthodoxy and overweening governmental power by generating their own distinctive virtues and values and by being independent locations of power and authority. The first idea envisions a comfortable congruence between civil society and government: the values and virtues - and habits and skills - cultivated in …

The Freedom Of Health, Abigail Moncrieff

Faculty Scholarship

What would have happened if the Patient Protection and Affordable Care Act (PPACA) really had authorized government “death panels” that would decide whether an elderly patient could get treatment? Leaving aside commerce clause and other constraints particular to Congress, would that kind of direct healthcare rationing be a constitutional exercise of governmental power in the United States? I think not. I argue here that an emergent substantive due process constraint would invalidate such an exercise; direct rationing of that kind would violate a constitutional “freedom of health” that is nascent in Supreme Court jurisprudence. Based on that logic, I argue …

Arbitration In Autumn, William W. Park

Faculty Scholarship

Often invoked as a metaphor for decline and decay, autumn also carries a sense of robust maturity bringing fruitful harvest and new beginnings. The season’s double symbolism evokes rival visions of arbitration today. Some observers see a golden age of cheap and cheerful proceedings as replaced by a costly complexity that fails arbitration’s promise of coherent and efficient dispute resolution. On closer scrutiny, however, arbitration reveals itself as having arrived at its autumn not in the sense of decay, but rather with vital maturity. Productive exchanges among the various stakeholders in the process serve to refine the counterpoise among accuracy, …

Pay For Banker Performance: Structuring Executive Compensation For Risk Regulation, Frederick Tung

Faculty Scholarship

Excessive risk taking by firm managers did not originate with the Financial Crisis of 2007-08. Though bankers had special incentives to take big risks in the period before the Crisis, the incentive effects of equity-based compensation have been understood for some time. Among other things, equity compensation tends to induce greater risk taking by aligning managers’ risk preferences with those of equity holders. Longstanding government guaranties of bank liabilities additionally served to intensify bankers’ risk taking incentives.

I propose to ameliorate this gambler’s incentive with a new approach to compensation at the largest banks, one that explicitly accounts for the …

Germ Shed Management In The United States, Kevin Outterson

Faculty Scholarship

The U.S. Medicare program reimburses only for discrete treatments of individuals with infections, but fails to pay for infection control or antibiotic stewardship more generally. By focusing solely on discrete hospitals and patients, Medicare ignores the larger epidemiological reality - that hospitals, nursing homes and other institutions operate within a germ shed. Under current Medicare rules, institutions that invest in infection control or antibiotic stewardship, may actually lose money and benefit rival firms in the market. In effect, current Medicare rules subsidize MRSA pollution. Worse yet, Medicare rules block potentially efficient Coasian contracts to promote private coordination within germ sheds.

Privacy Rights And Public Families, Khiara Bridges

Faculty Scholarship

This Article is based on eighteen months of anthropological fieldwork conducted among poor, pregnant women receiving prenatal care provided by the Prenatal Care Assistance Program (“PCAP”) at a large public hospital in New York City. The Prenatal Care Assistance Program (“PCAP”) is a special program within the New York State Medicaid program that provides comprehensive prenatal care services to otherwise uninsured or underinsured women. This Article attempts to accomplish two goals. The first goal is to argue that PCAP’s compelled consultations – with social workers, health educators, nutritionists, and financial officers – function as a gross and substantial intrusion by …

Bad News For Professor Koppelman: The Incidental Unconstitutionality Of The Individual Mandate, Gary S. Lawson, David B. Kopel

Faculty Scholarship

In "Bad News for Mail Robbers: The Obvious Constitutionality of Health Care Reform," Professor Andrew Koppelman concludes that the individual mandate in the Patient Protection and Affordable Care Act (PPACA) is constitutionally authorized as a law "necessary and proper for carrying into Execution" other aspects of the PPACA. However, the Necessary and Proper Clause rather plainly does not authorize the individual mandate.

The Necessary and Proper Clause incorporates basic norms drawn from eighteenth-century agency law, administrative law, and corporate law. From agency law, the clause embodies the venerable doctrine of principals and incidents: a law enacted under the clause must …

Improving Antibiotic Markets For Long Term Sustainability, Aaron S. Kesselheim, Kevin Outterson

Faculty Scholarship

The world faces a worsening public health crisis: A growing number of bacteria are resistant to available antibiotics. Yet there are few new antibiotics in the development pipeline to take the place of these increasingly ineffective drugs. We review a number of proposals intended to bolster drug development, including such financial incentives for pharmaceutical manufacturers as extending the effective patent life for new antibiotics. However, such strategies directly conflict with the clear need to reduce unnecessary antibiotic prescriptions and could actually increase prescription use. As an alternative, we recommend a two-prong, “integrated” strategy based on prizes administered through the insurance …

Rit Influenza Virus Database And Evidence For Differential Selection Pressures On Geographically Distinct Human Influenza A/H3n2 Virus Populations, Bindhu Satheeshkumar

Theses

Increasing amounts of data available from influenza virus genome sequencing projects have necessitated the need for centralized repositories for the collection, integration, and dissemination of these data to researchers for further research. The RIT Influenza Virus Database, a complete genome database for influenza viruses, has been created with a web interface so that users could query for viruses of interest and download complete genome sequences and metadata of isolates. The interface of the database is publicly accessible at http://bucatini.bioinformatics.rit.edu/bindhuURMC/. Even though it is known that influenza viruses are under constant evolution at the surface glycoproteins to develop drug resistance or …

The Second Amendment As Interpreted By Congress And The Court, Sean J. Kealy

Faculty Scholarship

In the last two years, the U.S. Supreme Court has finally offered a reasoned interpretation of the Second Amendment. By the slimmest of majorities in District of Columbia v. Heller and McDonald v. City of Chicago, the Supreme Court held that the Second Amendment supplies an individually-held right to bear arms; the government may place reasonable restrictions on gun ownership, but neither the federal government nor an individual state can deprive a person of their right to possess a handgun. Despite many pages of opinion, however, the majority in Heller offers an unsatisfying explanation for why the Second Amendment …

Called "Out" At Home: The One Strike Eviction Policy And Juvenile Court, Wendy J. Kaplan, David Rossman

Faculty Scholarship

One of the harshest collateral consequences of a juvenile delinquency case is the prospect of eviction from public housing. Under the federal government’s One Strike policy, public housing authorities are encouraged to evict families for any criminal act by their children, no matter how trivial. This politically popular policy creates more social ills than it cures. There is no evidence that it reduces crime in public housing, but there is abundant evidence that it makes families homeless, puts children out on the street, leads police departments to breach laws concerning confidentiality of juvenile proceedings, and creates conflicts of interest between …

Relationships Between High-Stakes Clinical Skills Exam Scores And Program Director Global Competency Ratings Of First-Year Pediatric Residents, E. E. Langenau, G. Pugliano, W. L. Roberts

PCOM Scholarly Works

Background: Responding to mandates from the Accreditation Council for Graduate Medical Education (ACGME) and American Osteopathic Association (AOA), residency programs have developed competency-based assessment tools. One such tool is the American College of Osteopathic Pediatricians (ACOP) program directors' annual report. High-stakes clinical skills licensing examinations, such as the Comprehensive Osteopathic Medical Licensing Examination Level 2-Performance Evaluation (COMLEX-USA Level 2-PE), also assess competency in several clinical domains. Objective: The purpose of this study is to investigate the relationships between program director competency ratings of first-year osteopathic residents in pediatrics andCOMLEX-USALevel 2-PE scores from2005 to 2009. Methods: The sample included all 94 …

American Vertigo: Dual Use, Prison Physicians, Research, And Guantanamo, George J. Annas

Faculty Scholarship

Physicians can be used by governments for nonmedical purposes, and physician acceptance of their nonmedical use is usually denoted as "dual loyalty, " although it is more analytically helpful to frame it "dual use. " Dual use of physicians has been on display at Guantanamo where physicians have consistently been used to break hunger strikes as part of the military security mission in ways that directly violate medical ethics. Guantanamo itself has also been seen worldwide as a uniquely horrible prison, which can tell us little about other American prisons. The contrary seems to be true: Guantanamo, and the use …

An Upper Limit For Macromolecular Crowding Effects, Andrew C. Miklos, Congang Li, Courtney D. Sorell, L. Andrew Lyon, Gary J. Pielak

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Background: Solutions containing high macromolecule concentrations are predicted to affect a number of protein properties compared to those properties in dilute solution. In cells, these macromolecular crowders have a large range of sizes and can occupy 30% or more of the available volume. We chose to study the stability and ps-ns internal dynamics of a globular protein whose radius is similar to 2 nm when crowded by a synthetic microgel composed of poly(N-isopropylacrylamide-co-acrylic acid) with particle radii of similar to 300 nm.

Results: Our studies revealed no change in protein rotational or ps-ns backbone dynamics and only mild …