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The Nih-Niaid Filariasis Research Reagent Resource Center, Michelle L. Michalski, Kathryn G. Griffiths, Steven A. Williams, Ray M. Kaplan, Andrew Moorhead

Biological Sciences: Faculty Publications

Filarial worms cause a variety of tropical diseases in humans; however, they are difficult to study because they have complex life cycles that require arthropod intermediate hosts and mammalian definitive hosts. Research efforts in industrialized countries are further complicated by the fact that some filarial nematodes that cause disease in humans are restricted in host specificity to humans alone. This potentially makes the commitment to research difficult, expensive, and restrictive. Over 40 years ago, the United States National Institutes of Health–National Institute of Allergy and Infectious Diseases (NIH-NIAID) established a resource from which investigators could obtain various filarial parasite species …

The New Hampshire, Vol. 101 [102], No. 22 (Nov. 29, 2011), The New Hampshire

The New Hampshire Print Edition

An independent student produced newspaper from the University of New Hampshire. This volume was printed as 101, but it is the 102nd volume in the series. This was corrected in pencil.

The George-Anne, Georgia Southern University

The George-Anne

• GSU to Host Playoffs
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Autoimmune Enteropathy With A Cd8+ Cd7- T-Cell Small Bowel Intraepithelial Lymphocytosis: Case Report And Literature Review, Shrinivas Bishu, Violeta Arsenescu, Eun Y. Lee, H. David Vargas, Willem J. S. De Villiers, Razvan Arsenescu

Surgery Faculty Publications

Background

Adult onset autoimmune enteropathy (AIE) is a rare condition characterized by diarrhea refractory to dietary therapy diagnosed in patients with evidence of autoimmune conditions. Auto-antibodies to gut epithelial cells and other tissues are commonly demonstrated. Despite increasing awareness, the pathogenesis, histologic, immunologic and clinical features of AIE remain uncertain. There remains controversy regarding the diagnostic criteria, the frequency and types of auto-antibodies and associated autoimmune conditions, and the extent and types of histologic and immunologic abnormalities. CD4+ T-cells are thought to at least responsible for this condition; whether other cell types, including B- and other T-cell subsets are involved, …

Carpal Tunnel Syndrome And The Flute, Tiffany Cagle

Honors Theses

No abstract provided.

The Sun Star, Vol. 31 No. 13 (November 29, 2011) , N/A N/A

Sun Star

No abstract provided.

Exploration And Comparison Of Methods For Combining Population- And Family-Based Genetic Association Using The Genetic Analysis Workshop 17 Mini-Exome, David W. Fardo, Anthony R. Druen, Jinze Liu, Lucia Mirea, Claire Infante-Rivard, Patrick Breheny

Biostatistics Faculty Publications

We examine the performance of various methods for combining family- and population-based genetic association data. Several approaches have been proposed for situations in which information is collected from both a subset of unrelated subjects and a subset of family members. Analyzing these samples separately is known to be inefficient, and it is important to determine the scenarios for which differing methods perform well. Others have investigated this question; however, no extensive simulations have been conducted, nor have these methods been applied to mini-exome-style data such as that provided by Genetic Analysis Workshop 17. We quantify the empirical power and false-positive …

The Current Volume 22 : Issue 14, Nova Southeastern University

Student Newspapers

No abstract provided.

Informal Support To First-Parents After Childbirth: A Qualitative Study In Low-Income Suburbs Of Dar Es Salaam, Tanzania, Columba Mbekenga, Andrea B. Pembe, Kyllike Christensson, Elisabeth Darj, Pia Olsson

School of Nursing & Midwifery, East Africa

Background: In Tanzania, and many sub-Saharan African countries, postpartum health programs have received less attention compared to other maternity care programs and therefore new parents rely on informal support. Knowledge on how informal support is understood by its stakeholders to be able to improve the health in families after childbirth is required. This study aimed to explore discourses on health related informal support to first-time parents after childbirth in low-income suburbs of Dar es Salaam, Tanzania.

Methods: Thirteen focus group discussions with first-time parents and female and male informal supporters were analysed by discourse analysis.

Results: The dominant discourse was …

Examining Criminal Justice Professionals’ Attitudes And Responsiveness Towards Intimidated Witnesses On The Local Level: An Exploratory Analysis, Moon Michon

Theses and Dissertations

Abstract EXAMINING CRIMINAL JUSTICE PROFESSIONALS’ ATTITUDES AND RESPONSIVENESS TOWARDS INTIMIDATED WITNESSES ON THE LOCAL LEVEL: AN EXPLORATORY ANALYSIS By Michon J. Moon, Ph.D. A dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy at Virginia Commonwealth University. Virginia Commonwealth University, 2011 Major Director: Laura J. Moriarty, Ph. D, Professor and Vice Provost of Academic and Faculty Affairs L. Douglas Wilder School of Government and Public Affairs The study explored criminal justice professionals’ attitudes and responsiveness toward witness intimidation on the local level based on their occupation and region of employment. Intimidated witnesses are vulnerable …

Sensory Modulation Disorder In Puerto Rican Preschoolers: Associated Risk Factors, Rosa L. Roman-Oyola

Theses and Dissertations

Sensory Modulation Disorder (SMD) reduces a child’s ability to respond to sensory stimuli in the environment in a manner that corresponds to the nature or intensity of the stimulus; this disorder therefore significantly can impact participation in developmentally appropriate play and functional activities. More studies are needed to enhance research in the field of SMD and aid the general community in understanding the disorder and its causes. The purpose of this study was to characterize the prevalence of SMD among Puerto Rican preschoolers and examine the relationship between specific risk factors (socioeconomic status, pre-natal alcohol exposure, low birth weight, preterm …

Social Ecological Constraints To Park Use In Communities With Quality Access, J. Aaron Hipp, Ravikumar Chockalingam, Deepti Adlakha

Center for Social Development Research

Evidence correlates physical activity, psychological restoration, and social health to proximity to parks and sites of recreation. The purpose of this study was to identify perceived constraints to park use in low-income communities facing significant health disparities, with access to underutilized parks. We used a series of focus groups with families, teens, and older adults in neighborhoods with similar demographic distribution and access to parks over 125 acres in size. Constraints to park use varied across age groups as well as across social ecological levels, with perceived constraints to individuals, user groups, communities, and society. Policies and interventions aimed at …

Store-Operated Calcium Channels In The Function Of Intracardiac Neurons, Timetria Bonds

USF Tampa Graduate Theses and Dissertations

Proper autonomic regulation of mammalian cardiac function is dependent upon very complex and precise communication among the intracardiac ganglia and individual neurons within the ganglia. An array of neuromodulators is found within the ganglia that direct neuronal activity by modulating the movement of calcium. The current study determines that opioidergic agonists, which have been found to contribute to severe cardiac disease states and intracellular calcium mobilization, are also responsible for changes in the function of the intracardiac neuron via their effects on store-operated calcium channels (SOCs).

Previous studies suggest that phosphorylation plays a role in SOC regulation. Using Fura-2 calcium …

Montana Kaimin, November 29, 2011, Students Of The University Of Montana, Missoula

Montana Kaimin, 1898-present

Student newspaper of the University of Montana, Missoula.

November 29, 2011, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

Studies On The Adherence Properties Of Plant Lectins And Bacterial Adhesins And Their Inhibition By Prebiotic Oligosaccharides And Bovine Colostrum Fractions, Maria X. Maldonado-Gomez

Department of Food Science and Technology: Dissertations, Theses, and Student Research

To initiate colonization and infection, most microbial pathogens must first recognize and adhere to cells in the host tissues. Adherence inhibition, therefore, can be used as a strategy for preventing infectious disease. In this research, we developed a simplified model using plant lectins and HEp-2 tissue culture cells to simulate bacterial adhesins-receptors interactions. The effect of lectin ligands and two prebiotic carbohydrates, galactooligosaccharide (GOS) and polydextrose (PDX) was measured with this approach. Lectins that were able to bind to the target cells were inhibited in the presence of the cognate ligands and at least one of the prebiotic carbohydrates. The …

Egfr Regulation Of Epidermal Barrier Function, Nhu Quynh T. Tran

Electronic Theses and Dissertations Archive

Keratinocyte terminal differentiation is the process that ultimately forms the epidermal barrier that is essential for mammals to survive in the ex utero environment. This process is tightly controlled by the expression of many well-characterized genes. Although a few of these genes are known to be regulated by the epidermal growth factor receptor (EGFR), an important regulator of multiple epidermal functions, neither the genome-wide scale of EGFR-mediated regulation nor the mechanisms by which EGFR signaling controls keratinocyte differentiation are well understood. Using microarray analysis we identified 2,676 genes that are regulated by EGF, a ligand of the EGFR. We further …

Computing Network Of Diseases And Pharmacological Entities Through The Integration Of Distributed Literature Mining And Ontology Mapping, Fazle Elahi Faisal

Electronic Theses and Dissertations Archive

The proliferation of "-omics" (such as, Genomics, Proteomics) and "-ology" (such as, System Biology, Cell Biology, Pharmacology) have spawned new frontiers of research in drug discovery and personalized medicine. A vast amount (21 million) of published research results are archived in the PubMed and are continually growing in size. To improve the accessibility and utility of such a large number of literatures, it is critical to develop a suit of semantic sensitive technology that is capable of discovering knowledge and can also infer possible new relationships based on statistical co-occurrences of meaningful terms or concepts. In this context, this thesis …

Design Of A Metatarsophalangeal Joint Implant Wear Tester, Kelly Wilton Schlachter

Electronic Theses and Dissertations Archive

The purpose of the present study was to design a wear tester for implants of the first metatarsophalangeal joint (FMTPJ), otherwise known as the first joint of the big toe. Many different designs of this type of implant from many different manufacturers are currently in clinical use, but there is no information in the open literature as to how these implants are tested for in vivo durability. There are several case studies, however, in which premature implant fractures were reported. It is possible that the incidence of such fractures might have been lower if standardized wear testing of FMTPJ implants …

Design And Evaluation Of A Novel Composite Chitosan-Poly(Lactide-Co-Glycolide) Microsphere Based System For Bone Tissue Engineering Applications, Marvin Magan Mecwan

Electronic Theses and Dissertations Archive

Nearly 60% to 67% of all injuries that occur annually within the US are due to musculoskeletal injuries, with over a million people requiring implants and bone grafting materials to reconstruct bone defects. Our lab has previously developed composite chitosan/nano-hydroxyapatite microsphere based bone grafts that had good compressive strengths, supported bone cell growth and mineralization in vitro, demonstrated biocompatibility and osteoconductivity in a rat calvarial defect model, and when loaded with rhBMP-2 was osteoinductive in a rat muscle pouch model. However, degradation of these scaffolds was very slow which may have limited the amount of new bone formed in vivo. …

Energy-Efficient Real-Time Data Compression In Wireless Sensor Networks, Tommy Szalapski, Sanjay Madria

Computer Science Faculty Research & Creative Works

Wireless sensor networks possess significant limitations in storage, bandwidth, and power. Additionally, real-time sensor networks cannot tolerate high latency. While some good compression algorithms exist specific to sensor networks, in this paper we present an energy-efficient method with high compression ratio that reduces latency, storage and bandwidth usage further in comparison with some other recently proposed algorithms. Our Huffman style compression scheme exploits temporal locality and delta compression to provide better bandwidth utilization in the network, thus reducing latency for real time applications. Our performance evaluations show comparable compression ratios and energy savings with a significant decrease in latency compared …

Differential Combination Of Cytokine And Interferon- Gamma +874 T/A Polymorphisms Determines Disease Severity In Pulmonary Tuberculosis., Ambreen Ansari, Zahra Hasan, Ghaffar Dawood, Rabia Hussain

Department of Pathology and Laboratory Medicine

Background:Mycobacterium tuberculosis infects nearly 1/3 of the world population and this reservoir forms the largest pool from which new cases arise. Among the cytokines, IFN-gamma is a key determinant in protection against tuberculosis. Single nucleotide polymorphisms (SNPs) in IFN-gamma gene (+874 T/A) which determine TT high ((hi)), AA low ((lo)) and TA intermediate ((int)) responder phenotypes have shown variable associations with tuberculosis disease outcome in different ethnic populations. The objective of the current study was to analyze IFN-gamma gene combinations with other IFN-gamma regulating cytokine genes (IL-10, TNF -alpha, IL-6) to see the effect of gene- combinations on disease …

Review: The Batterer As Parent: Addressing The Impact Of Domestic Violence On Family Dynamics, Angelo P. Giardino

Journal of Family Strengths

A Review of The Batterer as Parent: Addressing the Impact of Domestic Violence on Family Dynamics, 2nd Edition, by Lundy Bancroft, Jay G. Silverman, and D. Ritchie.

Commentary On "Child Welfare Waivers: The Stakes For Families", Stephanie Smith

Journal of Family Strengths

The purpose of this piece is to provide commentary of an article, Child Welfare Waivers: The Stakes for Your State, that discusses the recent reauthorization of the Title IV-E Child Welfare Waivers. The article provides an overview of funds available to the states for child welfare programs and their intended purpose and restrictions placed on use. As structured, the present system rewards states monetarily for maintaining foster care. Research from waiver programs shows promising results for improved outcomes at the same or lower financial cost by utilizing safe, proven alternatives to the current foster care system. Waiver funds also protect …

Commentary On "Practitioners’ Views Of Family Strengths: A Delphi Study", John Ronnau

Journal of Family Strengths

Commentary on "Practitioners’ Views of Family Strengths: A Delphi Study"

Commentary On "The Impact Of Family Stressors On The Social Development Of Adolescents In Residential Facilities", David Derezotes

Journal of Family Strengths

This is a commentary on “The impact of family stressors on the social development of adolescents admitted to a residential treatment facility,” by Cynthia Harr. This article examines the important but relatively understudied relationship of family dynamics in the social development of high risk teens in residential treatment facility (RTF) care. The commentary supports the author’s calls for a continuum of care involving greater cooperation with parents, and critiques and expands on some of the recommendations.

Commentary On “Connecting The Dots: Families And Children With Special Needs In A Rural Community”, Carl Tapia

Journal of Family Strengths

Starks et al. discuss an evaluation of educational initiatives to improve rural systems of care for children with special needs. Akin to the medical home neighborhood concept, building a holistic medical "village" entails improving collaboration, sharing accountability, and helping families to navigate the health care system. The article suggests that policymakers should include patient experiences of care in program evaluation, and they should build a community infrastructure for shared information and efficient communication.

Commentary On "Grandparents In Kinship Care: Help Or Hindrance To Family Preservation", Lori Lewis-Conerly

Journal of Family Strengths

Invited commentary on "Grandparents in Kinship Care: Help or Hindrance to Family Preservation."

Commentary On "An Examination Of The Contextual Environment Of Families With Sexually Abused Adolescents", Monit Cheung, Jacquelynn Duron

Journal of Family Strengths

The focus of this article is on the role of family in adolescent outcomes when sexual abuse has occurred. The authors identify environmental factors for promoting well-being among adolescents. Two hypotheses aim to examine the systemic influence on adolescents who have been sexually abused, with regard to: 1) mesosystemic barriers (i.e., low levels of school engagement and peer relationships), and 2) exosystemic risk factors (i.e., low levels of social support, socioeconomic status, and community safety, as well as large community size).

Commentary On "Resilient Families Help Make Resilient Children", Susan Landry

Journal of Family Strengths

This commentary outlines the strengths of the resilience-based family therapy approach. It describes the need for additional research in this area to advance the field and particular challenges that the field faces.