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2011

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The Hilltown Elder Network : A Study In Service To Elders : A Project Based Upon An Investigation At The Hilltown Community Development Center, Chesterfield, Ma., Deborah Grande Jan 2011

The Hilltown Elder Network : A Study In Service To Elders : A Project Based Upon An Investigation At The Hilltown Community Development Center, Chesterfield, Ma., Deborah Grande

Theses, Dissertations, and Projects

This study assessed the value and efficacy of in-home services offered by The Hilltown Elder Network (HEN). Pre-existing data first obtained through an annual "Client Satisfaction Survey" issued by HEN administration to HEN clients during FY 2010 was examined. Of the 100 surveys mailed, sixty-nine program participants between the ages of 62 and 95 years, the median age being 84, responded. The agency-designed mixed methods survey functioned to solicit program input, to gauge participant satisfaction and also operated as a tool to gather necessary data for program funding. The objective of the HEN Program was to help seniors to remain …


Preference Assessments For Older Adults With Dementia: Utility Of The Mswo Procedure And Assessment Of The Stability Of Preference, Paige B. Raetz Jan 2011

Preference Assessments For Older Adults With Dementia: Utility Of The Mswo Procedure And Assessment Of The Stability Of Preference, Paige B. Raetz

Dissertations

Individuals with dementia suffer from a variety of cognitive deficits that can lead to a lack of engagement in activities. In recent years, researchers have begun to look at ways to assess preferences in hopes that increased identification of leisure items may lead to increases in engagement. Due to the decline in cognitive status a simple questionnaire may not be sufficient to assess preference for this population. As a result, several recent studies have incorporated the use of systematic preference assessments to assess preference for leisure activities with adults with dementia using a paired stimulus format. The purpose of the …


Gvsu Press Releases, 2011, Grand Valley State University Jan 2011

Gvsu Press Releases, 2011, Grand Valley State University

University Press Releases, 1961-Present

A compilation of press releases for the year 2011 submitted by University Communications (formerly News & Information Services) to news agencies concerning the people, places, and events related to Grand Valley State University.


Efficacy And Safety Of A Modular Multi-Modal Exercise Program In Prostate Cancer Patients With Bone Metastases: A Randomized Controlled Trial, Daniel Galvao, Dennis R. Taaffe, Prue Cormie, Nigel Spry, Susan K. Chambers, Carolyn Peddle-Mcintyre, Michael Baker, James Denham, David Joseph, Geoff Groom, Robert Newton Jan 2011

Efficacy And Safety Of A Modular Multi-Modal Exercise Program In Prostate Cancer Patients With Bone Metastases: A Randomized Controlled Trial, Daniel Galvao, Dennis R. Taaffe, Prue Cormie, Nigel Spry, Susan K. Chambers, Carolyn Peddle-Mcintyre, Michael Baker, James Denham, David Joseph, Geoff Groom, Robert Newton

Research outputs 2011

Background: The presence of bone metastases has excluded participation of prostate cancer patients in exercise intervention studies to date and is also a relative contraindication to supervised exercise in the community setting because of concerns of fragility fracture. However, this group of patients often have developed significant muscle atrophy and functional impairments from prior and continuing androgen deprivation that is exacerbated by subsequent and more intensive interventions such as chemotherapy. The aim of this study is to determine the efficacy and safety of a modular multi-modal exercise program in prostate cancer patients with bone metastases. Methods/Design: Multi-site randomized controlled trial …


Individuals With Chronic Low Back Pain Have Greater Difficulty In Engaging In Positive Lifestyle Behaviours Than Those Without Back Pain: An Assessment Of Health Literacy, Andrew Briggs, Joanne Jordan, Peter O'Sullivan, Rachelle Buchbinder, Angus Burnett, Richard Osborne, Leon Straker Jan 2011

Individuals With Chronic Low Back Pain Have Greater Difficulty In Engaging In Positive Lifestyle Behaviours Than Those Without Back Pain: An Assessment Of Health Literacy, Andrew Briggs, Joanne Jordan, Peter O'Sullivan, Rachelle Buchbinder, Angus Burnett, Richard Osborne, Leon Straker

Research outputs 2011

Background: Despite the large volume of research dedicated to understanding chronic low back pain (CLBP), patient outcomes remain modest while healthcare costs continue to rise, creating a major public health burden. Health literacy - the ability to seek, understand and utilise health information - has been identified as an important factor in the course of other chronic conditions and may be important in the aetiology of CLBP. Many of the currently available health literacy measurement tools are limited since they measure narrow aspects of health literacy. The Health Literacy Measurement Scale (HeLMS) was developed recently to measure broader elements of …


A Randomized Controlled Trial Of Whole Body Vibration Exposure On Markers Of Bone Turn-Over In Postmenopausal Women, Sarah Turner, Margaret Torode, Mike Climstein, Geraldine Naughton, David Greene, Michael Baker, Maria Fiatarone Singh Jan 2011

A Randomized Controlled Trial Of Whole Body Vibration Exposure On Markers Of Bone Turn-Over In Postmenopausal Women, Sarah Turner, Margaret Torode, Mike Climstein, Geraldine Naughton, David Greene, Michael Baker, Maria Fiatarone Singh

Research outputs 2011

Purpose. To examine the effects of two doses of low-frequency (12 Hz), low-magnitude (0.3 g), whole body vibration on markers of bone formation and resorption in postmenopausal women. Methods. Women were recruited and randomized into a sham vibration control group, one time per week vibration group (1×/week), or three times per week vibration group (3×/week). Vibration exposure consisted of 20 minutes of intermittent vibration for the 1×/week and 3×/week groups, and sham vibration (<0.1 g) for the control group for eight weeks. Double-blinded primary outcome measures were urine markers of bone resorption: N-telopeptide X normalised to creatinine (NTx/Cr) and bone formation: bone-specific alkaline phosphatase (ALP). Results. Forty-six women (59.8 ± 6.2 years, median 7.3 years since menopause) were enrolled. NTx/Cr was significantly reduced (34.6%) in the 3×/wk vibration group but not in the 1×/wk vibration group compared with sham control (P<.01) group. No effect of time or group allocation was observed on the bone formation marker ALP (P=.27). Conclusion. We have shown for the first time that low-frequency, low-magnitude vibration 3×/week for eight weeks in postmenopausal women results in a significant reduction in NTx/Cr, a marker of bone resorption, when compared with sham vibration exposure.


In Search Of Wellness: Allied Health Professionals' Understandings Of Wellness In Childhood Disability Services, Lauren Breen, Helen Wildy, Sherry Saggers, Jeannine Millsteed, P Raghavendra Jan 2011

In Search Of Wellness: Allied Health Professionals' Understandings Of Wellness In Childhood Disability Services, Lauren Breen, Helen Wildy, Sherry Saggers, Jeannine Millsteed, P Raghavendra

Research outputs 2011

Purpose. Wellness approaches are not routine in childhood disability services, despite theoretical and empirical support and an increasing demand for them from health consumers and disability activists. We aimed to investigate how health professionals define or understand wellness and its practice in the context of childhood disability. Method. A qualitative, interpretive approach was taken. Semi-structured interviews were conducted with 23 health professionals (allied health therapists and managers) providing early intervention and ongoing therapy within four Australian childhood health and disability services. Years of experience providing services to children with disabilities and their families ranged from 6 months to 30 years …


Evaluation Of The Neurodegenerative Conditions Coordinated Care Program (Ncccp) In Western Australia: Barriers To Better Service Provision, Susanne T. Bahn, Margaret J. Giles Jan 2011

Evaluation Of The Neurodegenerative Conditions Coordinated Care Program (Ncccp) In Western Australia: Barriers To Better Service Provision, Susanne T. Bahn, Margaret J. Giles

Research outputs 2011

This paper details a 2009–2010 evaluation of the Neurodegenerative Conditions Coordinated Care Program (NCCCP) commissioned by the Disability Services Commission (DSC) in Western Australia (WA). The program, run by the Multiple Sclerosis Society of WA (Inc.) provides in-home care and supports and respite for people who are under the age of sixty-five and diagnosed with a rapidly degenerative neurological condition. In 2009, the identified barriers to the better provision of services included: shortage of quality out-of-home respite providers, and convoluted paperwork requirements to qualify for the program. Some service providers were unaware of the program and so were not referring …


Estimation Of The Centre Of Mass From Motion Capture And Force Plate Recordings: A Study On The Elderly, Sebastien Cotton, Michele Vanoncini, Philippe Fraisse, Nacim Ramdani, Emel Demircan, Andrew P. Murray, Thierry Keller Jan 2011

Estimation Of The Centre Of Mass From Motion Capture And Force Plate Recordings: A Study On The Elderly, Sebastien Cotton, Michele Vanoncini, Philippe Fraisse, Nacim Ramdani, Emel Demircan, Andrew P. Murray, Thierry Keller

Mechanical and Aerospace Engineering Faculty Publications

The estimation of the centre of mass position in humans is usually based on biomechanical models developed from anthropometric tables. This method can potentially introduce errors in studies involving elderly people, since the ageing process is typically associated with a modification of the distribution of the body mass. In this paper, an alternative technique is proposed, and evaluated with an experimental study on 9 elderly volunteers. The technique is based on a virtual chain, identified from experimental data and locating the subject's centre of mass. Its configuration defines the location of the centre of mass, and is a function of …


Distress Among Indigenous North Americans: Generalized And Culturally Relevant Stressors, Melissa L. Walls, Les B. Whitbeck Jan 2011

Distress Among Indigenous North Americans: Generalized And Culturally Relevant Stressors, Melissa L. Walls, Les B. Whitbeck

Department of Sociology: Faculty Publications

Stress process and life-course models of mental distress emphasize socio-cultural and historical processes that influence stress exposure and the impact of stress on mental health outcomes. Drawing from these theoretical orientations as well as concepts from the historical trauma literature, we examine the effects of culturally relevant and more generalized sources of stress on distress among North American Indigenous adults, and tests for the potential cumulative and interactive effects of stress on distress across the life-course via self-reported early childhood and adult/contemporary stressors. Results of OLS regression analyses reveal positive, significant associations between general stressors and distress as well as …


The Relationship Of Race And Social Integration On The Health Status Of Older Adults In An Urban City, Thomas T. Jordan Jan 2011

The Relationship Of Race And Social Integration On The Health Status Of Older Adults In An Urban City, Thomas T. Jordan

Dissertations, Theses, and Capstone Projects

Durkheim argues that an individual is more vulnerable to self-destruction the more s/he is detached from the collective. This dissertation will explore the relative impact of social integration on older adults who have transitioned into their new roles in the social structure in relationship to their physical (obesity) and psychological (stress) health status. Additionally, the dissertation examines how social integration varies in its impact from one racial group to another, and how such variations influence the health status of the older adults who are members of these groups.

This dissertation employs data from the Brookdale Center for Healthy Aging and …


The Elder Economic Security Initiative™: The Elder Economic Security Standard™ Index For Iowa, Gerontology Institute, University Of Massachusetts Boston, Wider Opportunities For Women Jan 2011

The Elder Economic Security Initiative™: The Elder Economic Security Standard™ Index For Iowa, Gerontology Institute, University Of Massachusetts Boston, Wider Opportunities For Women

Gerontology Institute Publications

This report addresses income adequacy for Iowa’s older adults using the national WOW-GI National Elder Economic Security Standard Index (Elder Index) methodology. The Elder Index benchmarks basic costs of living for elder households and illustrates how costs of living vary geographically and are based on the characteristics of elder households, including household size, home ownership or renter status and health status. The costs are based on market costs for basic needs of elder households and do not assume any public or private supports.


Risk Factors For Driving Cessation Vary By Race And Ethnicity, Elizabeth Dugan, Frank Porell, Chae Man Lee Jan 2011

Risk Factors For Driving Cessation Vary By Race And Ethnicity, Elizabeth Dugan, Frank Porell, Chae Man Lee

Gerontology Institute Publications

Driving is related to our identity and independence as well as allowing us to get needed goods, services, and social opportunities that enrich daily life. Yet with increasing age, the risk for developing threats to medical fitness to drive increases. Driving cessation is related to a long list of negative outcomes, such as: depression, social isolation, diminished access to health care, and diminished quality of life. We investigated risks for driving cessation, paying close attention to racial differences. This study used data from the Health and Retirement Study (HRS), 1998-2008. The study included N=46, 528 older people (age 65 and …


The Elder Economic Security Initiative™: The Elder Economic Security Standard™ Index For Colorado, Gerontology Institute, University Of Massachusetts Boston, Wider Opportunities For Women Jan 2011

The Elder Economic Security Initiative™: The Elder Economic Security Standard™ Index For Colorado, Gerontology Institute, University Of Massachusetts Boston, Wider Opportunities For Women

Gerontology Institute Publications

This report addresses income adequacy for Colorado’s older adults using the national WOW-GI National Elder Economic Security Standard Index (Elder Index) methodology. The Elder Index benchmarks basic costs of living for elder households and illustrates how costs of living vary geographically and are based on the characteristics of elder households, including household size, home ownership or renter status and health status. The costs are based on market costs for basic needs of elder households and do not assume any public or private supports.


Implementation Of Best Practices For Fall Prevention And Management In Long-Term Care, Cassandra Warner Frieson Jan 2011

Implementation Of Best Practices For Fall Prevention And Management In Long-Term Care, Cassandra Warner Frieson

Doctor of Nursing Practice (DNP)

No abstract provided.


Mobility, Balance, And Falls In Persons With Multiple Sclerosis, Jacob J. Sosnoff, Michael J. Socie, Morgan K. Boes, Brian M. Sandroff, John H. Pula, Yoojin Suh, Madeline Weikert, Steven Morrison, Robert W. Motl Jan 2011

Mobility, Balance, And Falls In Persons With Multiple Sclerosis, Jacob J. Sosnoff, Michael J. Socie, Morgan K. Boes, Brian M. Sandroff, John H. Pula, Yoojin Suh, Madeline Weikert, Steven Morrison, Robert W. Motl

Rehabilitation Sciences Faculty Publications

Background: There is a lack of information concerning the relation between objective measures of gait and balance and fall history in persons with MS (PwMS). This investigation assessed the relation between demographic, clinical, mobility and balance metrics and falls history in persons with multiple sclerosis (MS).

Methods: 52 ambulatory persons with MS (PwMS) participated in the investigation. All persons provided demographic information including fall history over the last 12 months. Disease status was assessed with Expanded Disability Status Scale (EDSS). Walking speed, coordination, endurance and postural control were quantified with a multidimensional mobility battery.

Results: Over 51% of the participants …


Elders’ Attitudes Toward Extending The Healthy Life Span, Victor G. Cicirelli Jan 2011

Elders’ Attitudes Toward Extending The Healthy Life Span, Victor G. Cicirelli

Department of Psychological Sciences Faculty Publications

Despite continuing debate between anti-aging researchers seeking major life span extension and concerned gerontologists and bioethicists, elders’ views have received little research attention. Study aimed to relate elders’ attitudes toward strong life span extension to psychosocial and background factors. Participants were 109 American elders (65% women) aged 60-99 (M = 77.08, SD = 9.05). Measures included attitudes toward living long and living forever, Desired Age, Death Acceptance, Goal Seeking, Internality, and background variables (age, gender, marital status, education, religion, health). Attitudes were more positive toward an extended life span than living forever (p < .01). In regression analyses, more positive attitudes were related to greater Desired Age, less Death Acceptance, greater Goal Seeking, and greater Internality, and to lower age and non-Christian religious affiliation. Qualitative analyses explored goals for various periods of additional life. Elders’ positive attitudes toward extended life need consideration by experts debating this issue.


Effects Of Two Group Approaches On Life Satisfaction And Mood Of Older Females In Nursing Homes, Bede Redpath Ryan Jan 2011

Effects Of Two Group Approaches On Life Satisfaction And Mood Of Older Females In Nursing Homes, Bede Redpath Ryan

Wayne State University Dissertations

The purpose of this study was to examine the effects of two group counseling therapy interventions on levels of life satisfaction and mood disturbance of older women, age 65+, living in two Detroit-based skilled nursing home facilities. This quasi-experimental, two-treatment group design examined the pretest-posttest data of two group counseling therapy interventions, Group Art Therapy (GAT) and Group Life Stories Narrative Therapy (GLSNT). Seventeen participants completed the bi-weekly, 90-minute sessions, over a four-week period. A univariate ANCOVA with group membership as fixed independent variable was used to compare life satisfaction post scores with pre scores as covariates. Mean scores were …


Effects Of Home Exercise On Immediate And Delayed Affect And Mood Among Rural Individuals At Risk For Type 2 Diabetes, Kevin S. Masters, Glen I. Spielmans, Rick A. Lacaille, Jason T. Goodson, Brian T. Larsen, Edward M. Heath, Andrea Knestel Jan 2011

Effects Of Home Exercise On Immediate And Delayed Affect And Mood Among Rural Individuals At Risk For Type 2 Diabetes, Kevin S. Masters, Glen I. Spielmans, Rick A. Lacaille, Jason T. Goodson, Brian T. Larsen, Edward M. Heath, Andrea Knestel

Journal of Social, Behavioral, and Health Sciences

Physical activity is important for reducing overweight and obesity and related health consequences. This study examined changes in mood following 16 weeks of exercise in a sample of 29 individuals residing in a rural area and at risk for developing Type 2 diabetes mellitus (T2DM). Significant positive mood changes were detected, with moderate to large effect sizes. Assessments also revealed significant delayed postexercise positive emotion changes. These findings extend research on the mood benefits of exercise to individuals residing in rural settings and at risk for T2DM and suggest that to gain a full understanding of the exercise-affect relation, investigators …


More Similar Than Different? Exploring Cultural Models Of Depression Among Latino Immigrants In Florida, Dinorah Martinez Tyson, Heide Castaneda, Milagro Porter, Marisel Quiroz, Iraida Carrion Jan 2011

More Similar Than Different? Exploring Cultural Models Of Depression Among Latino Immigrants In Florida, Dinorah Martinez Tyson, Heide Castaneda, Milagro Porter, Marisel Quiroz, Iraida Carrion

Anthropology Faculty Publications

The Surgeon General's report, “Culture, Race, and Ethnicity: A Supplement to Mental Health,” points to the need for subgroup specific mental health research that explores the cultural variation and heterogeneity of the Latino population. Guided by cognitive anthropological theories of culture, we utilized ethnographic interviewing techniques to explore cultural models of depression among foreign-born Mexican (), Cuban (), Columbian (), and island-born Puerto Ricans (), who represent the largest Latino groups in Florida. Results indicate that Colombian, Cuban, Mexican, and Puerto Rican immigrants showed strong intragroup consensus in their models of depression causality, symptoms, and treatment. We found more agreement …


Nursing Home Administrators' Personality And Nursing Home Quality: Correlations Between The Predictive Index And Cms Ratings, Kelly Anne Osbaldiston Jan 2011

Nursing Home Administrators' Personality And Nursing Home Quality: Correlations Between The Predictive Index And Cms Ratings, Kelly Anne Osbaldiston

Online Theses and Dissertations

The approximately two million residents in nursing homes are nearly totally dependent on the care they receive from the nursing homes' staff. The quality of care ranges from excellent to substandard, and the goal of this project is to understand how the top administrators' personality is related to the quality of the facility. Very little research has been done from an organizational psychology perspective on how to improve the care that residents receive in nursing homes. To help address this problem, I examined the relationship between administrator personality factors (measured by Predictive Index) and nursing home quality (measured by the …


Ovarian Hormones, Aging And Stress On Hippocampal Synaptic Plasticity, Michael R. Foy Jan 2011

Ovarian Hormones, Aging And Stress On Hippocampal Synaptic Plasticity, Michael R. Foy

Psychological Science Faculty Works

The ovarian steroid hormones estradiol and progesterone regulate a wide variety of non-reproductive functions in the central nervous system by interacting with molecular and cellular processes. A growing literature from studies using rodent models suggests that 17β-estradiol, the most potent of the biologically relevant estrogens, enhances synaptic transmission and the magnitude of long-term potentiation recorded from in vitro hippocampal slices. In contrast, progesterone has been shown to decrease synaptic transmission and reduce hippocampal long-term potentiation in this model system. Hippocampal long-term depression, another form of synaptic plasticity, occurs more prominently in slices from aged rats. A decrease in long-term potentiation …


The Cultural Context Of Alzheimer’S Disease: The Impact Of Perception And Knowledge On Willingness To Seek Medcial [I.E., Medical] Help Among Ghanaian Immigrants In The United States., Olivia Owusu-Boakyewaah Jan 2011

The Cultural Context Of Alzheimer’S Disease: The Impact Of Perception And Knowledge On Willingness To Seek Medcial [I.E., Medical] Help Among Ghanaian Immigrants In The United States., Olivia Owusu-Boakyewaah

Theses and Dissertations

This correlational study explored the knowledge, perceived seriousness, and willingness to seek medical help for Alzheimer’s Disease (AD) among Ghanaian Immigrants currently residing in the Unites States. Study participants were 163 Ghanaian Immigrants between the ages of 45 and 90, attending Ghanaian community churches in Virginia and Maryland. Significant results include a positive correlation between knowledge and perceived seriousness of the disease, perceived seriousness of the disease was negatively correlated with caregiving experience. These results as well as several seemingly counterintuitive findings are discussed in terms of the Health Disparities and Psychometric challenges. Specifically, these results points to the necessity …


Meanings Of Old Age: A Story In Three Voices, Rivka Tenenbaum-Precel Jan 2011

Meanings Of Old Age: A Story In Three Voices, Rivka Tenenbaum-Precel

Dissertations, Theses, and Capstone Projects

As the population of the Western world grows older, the need to understand the meaning of this stage in life grows in importance. Psychological research into the meaning of old age is posing questions on diverse levels, from that of individual ontogenesis to those of the family, community and society at large. Traditionally, developmental psychology has investigated different aspects of aging using measures of cognition, emotion, self-concept and well- being. Other approaches have examined the meaning of old age as embedded in cultural and social relations.

The present study uses a narrative approach to elicit the particular voices and interpretations …


Reforming Intestate Inheritance For Stepchildren And Stepparents, Terin Barbas Cremer Jan 2011

Reforming Intestate Inheritance For Stepchildren And Stepparents, Terin Barbas Cremer

Cardozo Journal of Equal Rights & Social Justice

The article advocates for reforming intestate inheritance laws to better address the needs of blended families, particularly stepchildren and stepparents, arguing that current laws fail to reflect the prevalence of such families. It proposes a factors test to determine inheritance rights based on the quality of the stepparent-stepchild relationship, aiming to align legal frameworks with modern family dynamics and better effectuate the decedent's intent.


Could Metabolic Syndrome, Lipodystrophy, And Aging Be Mesenchymal Stem Cell Exhaustion Syndromes?, Eduardo Mansilla, Vanina Díaz Aquino, Daniel Zambón, Gustavo Horacio Marin, Karina Mártire, Gustavo Roque, Thomas Ichim, Neil H. Riordan, Amit Patel, Flavio Sturla, Gustavo F. Larsen, Rubén Spretz, Luis Núñez, Carlos Soratti, Ricardo Ibar, Michiel Van Leeuwen, José María Tau, Hugo Drago, Alberto Maceira Jan 2011

Could Metabolic Syndrome, Lipodystrophy, And Aging Be Mesenchymal Stem Cell Exhaustion Syndromes?, Eduardo Mansilla, Vanina Díaz Aquino, Daniel Zambón, Gustavo Horacio Marin, Karina Mártire, Gustavo Roque, Thomas Ichim, Neil H. Riordan, Amit Patel, Flavio Sturla, Gustavo F. Larsen, Rubén Spretz, Luis Núñez, Carlos Soratti, Ricardo Ibar, Michiel Van Leeuwen, José María Tau, Hugo Drago, Alberto Maceira

Department of Chemical and Biomolecular Engineering: Faculty Publications

One of the most important and complex diseases ofmodern society is metabolic syndrome. This syndrome has not been completely understood, and therefore an effective treatment is not available yet. We propose a possible stem cell mechanism involved in the development ofmetabolic syndrome. This way of thinking lets us consider also other significant pathologies that could have similar etiopathogenic pathways, like lipodystrophic syndromes, progeria, and aging. All these clinical situations could be the consequence of a progressive and persistent stemcell exhaustion syndrome (SCES). Themain outcome of this SCES would be an irreversible loss of the effective regenerative mesenchymal stem cells (MSCs) …


Increased Transsulfuration Mediates Longevity And Dietary Restriction In Drosophila, Hadise Kabil, Omer Kabil, Ruma Banerjee, Lawrence G. Harshman, Scott D. Pletcher Jan 2011

Increased Transsulfuration Mediates Longevity And Dietary Restriction In Drosophila, Hadise Kabil, Omer Kabil, Ruma Banerjee, Lawrence G. Harshman, Scott D. Pletcher

School of Biological Sciences: Faculty Publications

The mechanisms through which dietary restriction enhances health and longevity in diverse species are unclear. The transsulfuration pathway (TSP) is a highly conserved mechanism for metabolizing the sulfur-containing amino acids, methionine and cysteine. Here we show that Drosophila cystathionine β-synthase (dCBS), which catalyzes the rate-determining step in the TSP, is a positive regulator of lifespan in Drosophila and that the pathway is required for the effects of diet restriction on animal physiology and lifespan. dCBS activity was up-regulated in flies exposed to reduced nutrient conditions, and ubiquitous or neuron-specific transgenic overexpression of dCBS enhanced longevity in fully fed animals. Inhibition …


Body Mass Index Is Associated With Dietary Patterns And Health Conditions In Georgia Centenarians, Dorothy B. Hausman, Mary Ann Johnson, Adam Davey, Leonard W. Poon Jan 2011

Body Mass Index Is Associated With Dietary Patterns And Health Conditions In Georgia Centenarians, Dorothy B. Hausman, Mary Ann Johnson, Adam Davey, Leonard W. Poon

Department of Nutrition and Health Sciences: Faculty Publications

Associations between body mass index (BMI) and dietary patterns and health conditions were explored in a population-based multiethnic sample of centenarians from northern Georgia. BMI ≤20 and ≥25 was prevalent in 30.9% and 25.3% of study participants, respectively. In a series of logistic regression analyses controlled for gender and place of residence, the probability of having BMI ≥25 was increased by being black versus white and having a low citrus fruit, noncitrus fruit, orange/yellow vegetable or total fruit and vegetable intake. The probability of having BMI ≤20 was not associated with dietary intake. When controlled for race, gender, residence, and …


2011-2012 Lindenwood University Lcie Course Catalog, Lindenwood University Jan 2011

2011-2012 Lindenwood University Lcie Course Catalog, Lindenwood University

Course Catalogs

Lindenwood University LCIE Course Catalog


Self-Rated Health Status And Cardiorespiratory Fitness As Predictors Of Mortality In Men, Jennifer Gander, Duck-Chul Lee, Xuemei Sui, James R. Hébert, Steven P. Hooker, Steven N. Blair Jan 2011

Self-Rated Health Status And Cardiorespiratory Fitness As Predictors Of Mortality In Men, Jennifer Gander, Duck-Chul Lee, Xuemei Sui, James R. Hébert, Steven P. Hooker, Steven N. Blair

Faculty Publications

Self-rated health (SRH) and cardiorespiratory fitness (fitness) are independent risk factors for all-cause mortality. The purpose of this report is to examine the single and joint effects of these exposures on mortality risk. The study included 18 488 men who completed a health survey, clinical examination and a maximal exercise treadmill test during 1987–2003. Cox regression analysis was used to quantify the associations of SRH and fitness with all-cause mortality. There were 262 deaths during 17 years of follow-up. There was a significant inverse trend (ptrend <0.05) for mortality across SRH categories after adjustment for age, examination year, body mass index, physical activity, smoking, alcohol consumption, abnormal ECG, hypertension, hypercholesterolaemia, cardiovascular disease, diabetes and cancer. Adjustment for fitness attenuated the association (p value =0.09). The authors also observed an inverse association between fitness and mortality after controlling for the same covariates and SRH (ptrend = 0.006). The combined analysis of SRH and fitness showed that fit …