Digital Commons Network^™

Regulation Of Apoptotic Effects By Erythrocarpine E, A Cytotoxic Limonoid From Chisocheton Erythrocarpus In Hsc-4 Human Oral Cancer Cells, N.H. Nagoor, J.M.N. Shah, L.C. Soon, L.L. In, K. Mohammad, K. Awang

Research Publications (2011 to 2015)

The aim of this study was to determine the cytotoxic and apoptotic effects of erythrocarpine E (CEB4), a limonoid extracted from Chisocheton erythrocarpus on human oral squamous cell carcinoma. Based on preliminary dimethyl-2-thiazolyl-2,5-diphenyl-2H-tetrazolium bromide (MTT) assays, CEB4 treated HSC-4 cells demonstrated a cytotoxic effect and inhibited cell proliferation in a time and dose dependent manner with an IC(50) value of 4.0±1.9 µM within 24 h of treatment. CEB4 was also found to have minimal cytotoxic effects on the normal cell line, NHBE with cell viability levels maintained above 80% upon treatment. Annexin V-fluorescein isothiocyanate (FITC), poly-ADP ribose polymerase (PARP) cleavage …

Relationships Of The Heteronchocleidids (Heteronchocleidus, Eutrianchoratus And Trianchoratus) As Inferred From Ribosomal Dna Nucleotide Sequence Data, W.B. Tan, Mun Yik Fong, L.H.S. Lim

Research Publications (2011 to 2015)

The monogeneans, Heteronchocleidus, Eutrianchoratus and Trianchoratus, were postulated to be closely related based on their haptoral hard parts of three well-developed anchors and one vestigial anchor. In this present study, partial 28S rDNA sequences from 12 heteronchocleidids species (10 Trianchoratus spp. and two Eutrianchoratus spp.) were obtained. Phylogenetic trees generated based on 28S rDNA (from the present study and GenBank) using neighbour-joining (NJ), maximum parsimony (MP), maximum likelihood (ML) and Bayesian inference (BI) analyses show that members of these three genera constitute a clade. Within this main monophyletic clade are the Heteronchocleidus-Eutrianchoratus and the Trianchoratus clades. This suggests that the …

Spei Restriction Enzyme Displays Greater Discriminatory Power Than Xbai Enzyme Does In A Pulsed-Field Gel Electrophoresis Study On 146 Clinical Burkholderia Pseudomallei Isolates, K.H. Chua, K.H. See, Kwai Lin Thong, S.D. Puthucheary

Research Publications (2011 to 2015)

Restriction enzymes SpeI and XbaI were used in a pulsed-field gel electrophoresis (PFGE) study for molecular characterization of 146 clinical Burkholderia pseudomallei isolates. The PFGE parameters were optimized to enable comparable, reproducible, and robust results. The optimized parameters for both SpeI and XbaI restriction enzymes used in this study were 200 V and a pulse time of 5 to 65 s for a 28-h runtime. Using SpeI, 9 different clusters were identified, whereas 6 clusters were identified by XbaI digestion, which exhibited 85 similarity to SpeI. SpeI (discrimination index D=0.854) showed higher discriminatory power than XbaI did (D=0.464).

Taxonomy And Dna Sequence Databases: A Perfect Match?, J.J. Wilson

Research Publications (2011 to 2015)

No abstract provided.

The Influence Of Scuba Divers’ Personality, Experience,And Demographic Profile On Their Underwater Behavior, G. Musa, W.T. Seng, T. Thirumoorthy, M. Abessi

Research Publications (2011 to 2015)

Scuba diving activity is known to cause detrimental impact on the marine environment and its sustainability. This study explores the influence of divers’ personality, experience, and demographic profile on their underwater behavior. Data were collected using convenience sampling among divers in Malaysia. A total of 302 questionnaires were returned and analyzed. The results show that divers are generally responsible underwater. Scuba diving experience parameters of duration of involvement, number of dives, self-rating experience, and diving frequency influence underwater behavior. Divers with high neuroticism are more likely to be irresponsible, while high agreeableness personality factor is related to more responsible behavior …

Effects Of Benzylaminopurine And Naphthalene Acetic Acid On Proliferation And Shoot Growth Of Pineapple (Ananas Comosus L. Merr) In Vitro, A.M. Al-Saif, A.B.M.S. Hossain, Rosna Mat Taha

Research Publications (2011 to 2015)

This study was conducted to evaluate the pineapple regeneration and shoot growth as affected by 6-benzylaminopurine (BAP) at 2.0 mg/l and naphthalene acetic acid (NAA) at 0.2 mg/l in vitro. BAP and NAA at the concentration of 2.0 and 0.2 mg/l were used in this study. BAP at 2.0 mg/l significantly affected the production of shoots per explant, shoot length and weight. Total shoot length was higher in BAP (2 mg/l) than in control (MS medium without hormone) and NAA (0.2mg/l) after 10, 20, 30, 40, 50 and 60 days incubation period. Total shoot length was highest in BAP in …

Enterovirus 71 In Malaysia: A Decade Later, Yoke Fun Chan, I.C. Sam, K.L. Wee, Sazaly Abubakar

Research Publications (2011 to 2015)

In the last decade, Malaysia has experienced several hand, foot and mouth disease (HFMD) epidemics, complicated by fatalities due to severe neurological involvement. Enterovirus 71 (EV-71) has been implicated as the major causative agent for these epidemics. EV-71 infection is a global public health problem with pandemic potential. In many parts of Asia-Pacific, the virus has emerged as one of the most deadly virus infections amongst young children. The virus is highly transmissible through faecal-oral route and respiratory droplets. A recent rise in neurological complications and deaths suggests that the viruses currently circulating may be more virulent. The major risk …

Kinetic And Mechanism Studies Of The Adsorption Of Lead Onto Waste Cow Bone Powder (Wcbp) Surfaces, J. Cha, M. Cui, M. Jang, S.H. Cho, D.H. Moon, J. Khim

Research Publications (2011 to 2015)

This study examines the adsorption isotherms, kinetics and mechanisms of Pb2+ sorption onto waste cow bone powder (WCBP) surfaces. The concentrations of Pb2+ in the study range from 10 to 90 mg/L. Although the sorption data follow the Langmuir and Freundlich isotherm, a detailed examination reveals that surface sorption or complexation and co-precipitation are the most important mechanisms, along with possibly ion exchange and solid diffusion also contributing to the overall sorption process. The co-precipitation of Pb2+ with the calcium hydroxyapatite (Ca-HAP) is implied by significant changes in Ca2+ and PO4 3- concentrations during the metal sorption processes. The Pb2+ …

Energy Economical And Environmental Analysis Of Industrial Boilers Using Fuel Switching, A.E. Atabani, S. Rahman, A.S. Silitonga, A.H. Sebayang

Research Publications (2011 to 2015)

The successful implementation of the industrialization plan in Malaysia in 1985 has led to change this country from an agricultural economy into industrial based economy. The industrial sector represents the highest consuming sector across all other sectors and accounts for about 48 of all total energy demand. This study is concerned with an energy saving, economic and environmental analysis of industrial boilers in Malaysian paper and pulp industries when applying the concept of fuel switching. It has been found that 11,946 ton of CO2 and RM 1,872,532 could be saved annually, when switching between diesel fuel and biomass by a …

Evaluation Of N ε-(Carboxymethyl)Lysine And Lipid Peroxidation In Multiethnic Malaysian Subjects With Type 2 Diabetes Mellitus, K.A.A. Ahmed, S. Muniandy, I.S. Ismail, R.S. Ali, Z.H. Alhamodi

Research Publications (2011 to 2015)

The glycoxidation product, N ε-(carboxymethyl)lysine (CML), is formed during reaction of glucose with protein under oxidative conditions. The aim of the study was to evaluate the levels of the most common glycoxidation product; N ε-(carboxymethyl)lysine (CML) and the most advanced lipoxidation product, malondialdehyde (MDA) in type 2 diabetic Malay, Indian, and Chinese ethnic groups in the Malaysian population. Studies were performed on age-matched Malay, Indian, and Chinese subjects with type 2 diabetes mellitus. Different biochemical parameters including serum levels of CML, MDA, lipid profile, glucose, and hemoglobin A1c (HbA 1c) were measured by standard methods. The relationships between circulating CML …

Factors Associated With High Prevalence Of Intestinal Protozoan Infections Among Patients In Sana'a City, Yemen, Naelah A. Alyousefi, Mohammed A. K. Mahdy, Rohela Mahmud, Yvonne Ai Lian Lim

Research Publications (2011 to 2015)

BACKGROUND: Intestinal protozoan diseases in Yemen are a significant health problem with prevalence ranging from 18 to 27. The present study is a cross-sectional study aimed at determining the factors associated with the high prevalence of intestinal protozoan infections among patients seeking health care in Sana'a City, the capital of Yemen. METHODOLOGY/PRINCIPAL FINDINGS: Stool samples were collected from 503 patients aged between 1 and 80 years old; 219 were males and 284 females. Biodata were collected via pretested standard questionnaire. Faecal samples were processed and examined for (oo)cysts or ova using a wet mount preparation after formal-ether concentration technique. Cryptosporidium …

Hepatoprotective Effects Of Orthosiphon Stamineus Extract On Thioacetamide-Induced Liver Cirrhosis In Rats, Mohammed A. Alshawsh, Mahmood Ameen Abdulla, Salmah Ismail, Zahra A. Amin

Research Publications (2011 to 2015)

Orthosiphon stamineus as medicinal plant is commonly used in Malaysia for treatment of hepatitis and jaundice; in this study, the ethanol extracts were applied to evaluate the hepatoprotective effects in a thioacetamide-induced hepatotoxic model in Sprague Dawley rats. Five groups of adult rats were arranged as follows:Group 1 (normal control group), Group 2 Thioacetamide (TAA) as positive control (hepatotoxic group), Group 3 Silymarin as a well-known standard drug (hepatoprotective group), and Groups 4 and 5 as high and low dose (treatment groups). After 60-day treatment, all rats were sacrificed. The hepatotoxic group showed a coarse granulation on the liver surface …

Mahmood Merican Award For Masters In Orthopaedic Surgery Trainees In Malaysia, T.S. Ahmad

Research Publications (2011 to 2015)

The Mahmood Merican Award is an annual award for the best original scientific or clinical study submitted by young trainees in orthopaedic surgery in Malaysia, for presentation during the annual scientific meeting of the Malaysian Orthopaedic Association (MOA). This award was initiated in 1997 to encourage high standard of research and scientific presentations among young trainees.A cash prize of RM 1,000 was donated by Dato Dr Mahmood Merican. All Award finalists will represent MOA as ambassadors to regional orthopaedic association meetings, a duty that will be fully sponsored by MOA.

Mucuna Pruriens Linn. Seed Extract Pretreatment Protects Against Cardiorespiratory And Neuromuscular Depressant Effects Of Naja Sputatrix (Javan Spitting Cobra) Venom In Rats, S.Y. Fung, N.H. Tan, S.M. Sim, E. Marinello, R. Guerranti

Research Publications (2011 to 2015)

Mucuna pruriens has been used by native Nigerians as a prophylactic for snakebite. The protective effects of M. pruriens seed extract (MPE) were investigated against the pharmacological actions of N. sputatrix (Javan spitting cobra) venom in rats. The results showed that MPE-pretreatment protected against cardiorespiratory and, to a lesser extent, neuromuscular depressant effects of N. sputatrix venom. These may be explained at least in part by the neutralisation of the cobra venom toxins by anti-MPE antibodies elicited by the MPE pretreatment.

The Application Of Melatonin And Platelet-Rich Plasma In The Development Of A Bioactive Calcium Aluminate Bone Regenerative Scaffold, William Clafshenkel

Electronic Theses and Dissertations

Over 500,000 bone graft procedures are conducted annually within the United States. Autografts contribute to donor site complications and disease transmission with allografts has been described. Many ceramics are only osteoconductive and are brittle, limiting their clinical use. Thus, the objective of this study was to create a bone substitute with osteoinductive properties similar to natural bone using the ceramic biomaterial calcium aluminate (CA). Calcium aluminate materials are durable and remain moldable for an extended period of time at room temperature. Further, the surfaces of CA scaffolds can be modified with biological agents through simple chemical means to locally deliver …

The Lived Experience Of K-12 Educators Who Practice Within An Acute Care Inpatient Psychiatric Hospital, William Davies

Electronic Theses and Dissertations

Human service professionals serve roles in society in which they are responsible for the well-being of countless numbers of people. These professionals span important fields including nursing, social work, law enforcement, medicine, and education. This study focused on a specific subgroup of human service professionals: special education teachers who practice within an acute care inpatient psychiatric facility. The purpose of this qualitative study was to investigate the lived experiences of educators in order to identify emergent themes that best describe their experiences.

The psychiatric hospital in this study is a large hospital located within an urban area of the Northeastern …

Measuring Tumor Aggressiveness And Targeting Metastatic Lesions With Fluorescent Phlip, Yana K. Reshetnyak, Lan Yao, Sida Zheng, Sergey Kuznetsov, Donald M. Engelman, Oleg A. Andreev

Physics Faculty Publications

Purpose: Malignant cancer foci develop acidic extracellular environments. Mild acidic conditions trigger insertion and folding of the pH (low) insertion peptide (pHLIP^TM) across a cellular membrane, enabling targeting of such lesions.

Procedures: We employed optical imaging to follow targeting by fluorescent pHLIP given i.v. in mice. For visualization, Cy5.5 and Alexa750 were covalently attached to the N terminus of pHLIP, which stays outside of a cell membrane after transmembrane insertion.

Results: We demonstrate that pHLIP targets: (a) tumors of different origins established by subcutaneous injection of cancer cells, (b) spontaneous prostate tumors in TRAMP mice and (c) metastatic …

Rollins Magazine, Spring 2011, Rollins College Office Of Marketing And Communications

Rollins Magazine

Issue Title: "Brave New Academics"

Rollins Magazine, Fall 2011, Rollins College Office Of Marketing And Communications

Rollins Magazine

Issue Title: "High-Impact Learning"

Annual Report, Mississippi State University Foundation, Amy Cagle

MSUF Annual Reports

This document is the annual report for Mississippi State University Foundation.

Mississippi State University - Student Enrollment Profile - Fall 2011, Mississippi State University Office Of Institutional Research And Effectiveness

Enrollment Profiles

No abstract provided.

Occurrence Of Blastocystis In Water Of Two Rivers From Recreational Areas In Malaysia, I. Ithoi, A. Jali, J.W. Mak, W.Y. Wan Sulaiman, R. Mahmud

Research Publications (2011 to 2015)

This study reports the occurrence of Blastocystis in water from two rivers, Sungai Congkak and Sungai Batu, located in recreational areas in Malaysia. This protozoan was detected in samples from both rivers with an average of 33.3% and 22.1%, respectively. It was detected highest at the downstream (73.8% and 33.8%) followed by midstream (17.5% and 25.0%) and upstream (8.8% and 7.5%) stations, with additionally higher detection during holidays (with average 47.5% and 30.8%) than week days (with average 19.2% and 13.3%), in both rivers, respectively. There was a strong association with the daily activities of locals and visitors, who came …

Prevalence Of Bronchial Asthma Among Orang Asli In Peninsular Malaysia, R. Ngui, Yvonne Ai Lian Lim, S. C. Chow, J. A. De Bruyne, C. K. Liam

Research Publications (2011 to 2015)

A survey was carried out to determine the prevalence of bronchial asthma and their contributing risk factors among Orang Asli subgroups living in Malaysia using IUATLD questionnaire and spirometry without being discriminatory towards age or gender. Of the 1171 distributed questionnaires, 716 (61.1) comprising of 62.7 Semai Pahang, 51.3 Temiar, 74.2 Mah Meri, 65.6 Semai Perak, 53.6 Temuan, 53.8 Semelai, 61.1 Jakun and 67.4 Orang Kuala subgroups completed their questionnaire and were included in the data analysis. Participants comprised 549 (76.7) children and 167 (23.3) adults, age between 1 to 83 years old, 304 (42.5) males and 412 (57.5) females. …

Studies On Seed And Forage Yield In 10 Populations Of Sainfoin (Onobrychis Saliva) Grown As Spaced Plants And Swards, S. Mohajer, A.A. Jafari, R.M. Taha

Research Publications (2011 to 2015)

In order to study seed and dry matter (DM) yield and relationships between yield and morphological traits, 10 populations of sainfoin (Onobrychis saliva), were assessed in two separate experiments under sward and spaced plant conditions using complete block design with two replications, in Karaj, Iran, during 2004-2007. The data were collected for seed yield, DM yield, plant height, stem number per m(2), flowering date, inflorescences length and 1000-grain weight. The data were analyzed for individual experiment and combined over two experiments. Results showed significant differences among populations for all of traits except 1000-grain weight in sward and DM yield and …

The Concept Of Two-Dimensional Electrophoresis-Guided Purification Proven By Isolation Of Rhodocetin From Calloselasma Rhodostoma (Malayan Pit Viper), M.S. Tang, J. Vejayan, H. Ibrahim

Research Publications (2011 to 2015)

Two-dimensional gel electrophoresis (2DE) is an important tool for investigating the complexity of snake venom proteomes. Apart from applications based on whole proteome analysis, we suggest that 2DE can be used as an assay to guide the progress of protein purification. The aim of this study was to prove the feasibility of this concept by using it to purify rhodocetin from Calloselasma rhodostoma venom. Rhodocetin (α subunit) spot on the 2DE profile of C. rhodostoma venom was first identified and confirmed by mass spectrometry, with a molecular mass of 16 kDa and calculated pI of 5.16. Rhodocetin was subsequently purified …

Massive Modularity, Content Integration, And Language, Collin Rice

Philosophy Faculty Research and Scholarship

One of the obstacles facing massive modularity is how a pervasively modular mind might generate non-domain-specific thoughts by integrating the content produced by various domain-specific modules. Peter Carruthers has recently argued that the operations of the language faculty are constitutive of the process by which the human mind is able to integrate content from heterogeneous conceptual domains. In this article, I first argue that Carruthers’s data do not provide support for either of two possible interpretations of his thesis. In addition, I provide empirical and theoretical reasons for thinking content integration is performed external to the language faculty.

Proceedings Of The 123rd Annual Meeting Of The Iowa Academy Of Science [Program, 2011], Iowa Academy Of Science

Iowa Academy of Science Documents

Contents:

Program Summary --- 2-3
Acknowledgements --- 4
Contents --- 5
Welcome --- 5
Iowa Junior Academy of Science Competition --- 6
Geology Special Event Using Geographic Information Systems in Iowa's K-16 Classrooms --- 7
General Session I-Roaming Mars, a Personal Perspective --- 8
Iowa Junior Academy of Science Award Luncheon --- 9
Iowa Academy of Science Business Meeting --- 9
Iowa Academy of Science Volunteers for 2010-2011 --- 10
Symposium A-Unintended Health & Environmental Consequences of Confinement Agriculture --- 11
Symposium B-Investigating Forensic Science --- 12
Symposium C-150th Anniversary-Science and the Civil War --- 13
Symposia Speakers --- 14-15 …

6-Ohda Generated Ros Induces Dna Damage And P53- And Puma-Dependent Cell Death, Alison I. Bernstein, Sean P. Garrison, Gerard P. Zambetti, Karen L. O'Malley

Open Access Publications

No abstract provided.

Nonlinear Interactions Between Excitatory And Inhibitory Retinal Synapses Control Visual Output, Botir T. Sagdullaev, Erika D. Eggers, Robert Purgert, Peter D. Lukasiewicz

Open Access Publications

No abstract provided.

Caenorhabditis Briggsae Recombinant Inbred Line Genotypes Reveal Inter-Strain Incompatibility And The Rvolution Of Recombination, Joseph A. Ross, Daniel C. Koboldt, Julia E. Staisch, Helen M. Chamberlin, Bhagwati P. Gupta, Raymond D. Miller, Scott E. Baird, Eric S. Haag

Open Access Publications

No abstract provided.