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2010

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Haploinsufficiency Of Rai1 And Its Effect On Bdnf Expression, Sun Kim Dec 2010

Haploinsufficiency Of Rai1 And Its Effect On Bdnf Expression, Sun Kim

Theses and Dissertations

Smith-Magenis Syndrome (SMS) [OMIM, #182290] is a congenital anomaly and mental retardation (MCA/MR) syndrome associated with deletion of chromosome17p11.2 [1]. The clinical phenotype has been well described and includes minor craniofacial anomalies, self-injurious behaviors as well as sleep disturbances, speech delays, and obesity [1,2,3]. The incidence of SMS is estimated to be ~ 1:15,000 - 25,000 births [2,6]. Among SMS patients, ~90% are comprised of 17p11.2 deletions, while ~10% have RAI1 mutations [8]. All 17p11.2 deletions associated with SMS include RAI1 deletion [10]. RAI1 is thought to function as a transcriptional factor although its cellular role is still unclear. First, …


Examination Of Locus Of Control, Health Locus Of Control And Their Key Predictors In Urban Vs. Rural Populations, Mark T. Zimmerman Dec 2010

Examination Of Locus Of Control, Health Locus Of Control And Their Key Predictors In Urban Vs. Rural Populations, Mark T. Zimmerman

Electronic Theses and Dissertations Archive

The purpose of this study was to utilize a quantitative survey methodology, which explored the characteristicsof locus of control and health locus of control between a rural Tennessee population and an urban Tennessee population using scores from Rotter's Internal-External Locus of Control Scale (LOC) and the Multidimensional Health Locus of Control Scale (HLOC). The results of this study help bridge the gap in the limited studies available that use LOC and HLOC to explore the differences between the two populations. Demographic information on the survey (age, gender, race, annual household income, size of household, level of education, spirituality) and the …


Information-Preserving Structures: A General Framework For Quantum Zero-Error Information, Robin Blume-Kohout, Hui Khoon Ng, David Poulin, Lorenza Viola Dec 2010

Information-Preserving Structures: A General Framework For Quantum Zero-Error Information, Robin Blume-Kohout, Hui Khoon Ng, David Poulin, Lorenza Viola

Dartmouth Scholarship

Quantum systems carry information. Quantum theory supports at least two distinct kinds of information (classical and quantum), and a variety of different ways to encode and preserve information in physical systems. A system’s ability to carry information is constrained and defined by the noise in its dynamics. This paper introduces an operational framework, using information-preserving structures, to classify all the kinds of information that can be perfectly (i.e., with zero error) preserved by quantum dynamics. We prove that every perfectly preserved code has the same structure as a matrix algebra, and that preserved information can always be corrected. We …


Gsu View, 2010-12-06, Office Of Public Affairs Dec 2010

Gsu View, 2010-12-06, Office Of Public Affairs

GSU View

Newsletter published by Governors State University 2007-current.


Deafdigest: Deaf Sports News December 6, 2010, Barry Strassler Dec 2010

Deafdigest: Deaf Sports News December 6, 2010, Barry Strassler

DeafDigest Sports 2010

No abstract provided.


Commonwealth Times 2010-12-06 Dec 2010

Commonwealth Times 2010-12-06

Commonwealth Times, 1969-

No abstract provided.


Mustang Daily, December 6, 2010 Dec 2010

Mustang Daily, December 6, 2010

Cal Poly Student Newspaper

Student newspaper of California Polytechnic State University, San Luis Obispo, CA.


The Statesman, V. 54, I. 15, Stony Brook University Dec 2010

The Statesman, V. 54, I. 15, Stony Brook University

Stony Brook Statesman-Sucolian

v. 54, i. 15


Umsl Magazine - Fall 2010, University Of Missouri-St. Louis Dec 2010

Umsl Magazine - Fall 2010, University Of Missouri-St. Louis

UMSL Magazine and other UMSL Magazines

The University of Missouri–St. Louis publishes UMSL Magazine for alumni and friends. The magazine highlights excellence at the university. Circulation is 79,000, and the magazine is released twice a year.


December 6, 2010, James Madison University Dec 2010

December 6, 2010, James Madison University

The Breeze, 2010-2019

The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.


Dual Inhibition Of Sodium-Mediated Proton And Calcium Efflux Triggers Non-Apoptotic Cell Death In Malignant Gliomas, William Harley, Candace Floyd, Tamara Dunn, Xiao-Dong Zhang, Tsung-Yu Chen, Manu Hegde, Hasan Palandoken, Michael H. Nantz, Leonardo Leon, K.L. Carraway Iii, Bruce Lyeth, Fredric A. Gorin Dec 2010

Dual Inhibition Of Sodium-Mediated Proton And Calcium Efflux Triggers Non-Apoptotic Cell Death In Malignant Gliomas, William Harley, Candace Floyd, Tamara Dunn, Xiao-Dong Zhang, Tsung-Yu Chen, Manu Hegde, Hasan Palandoken, Michael H. Nantz, Leonardo Leon, K.L. Carraway Iii, Bruce Lyeth, Fredric A. Gorin

Chemistry and Biochemistry

Malignant glioma cells maintain an elevated intracellular pH (pHi) within hypoxic–ischemic tumormicroenvironments through persistent activation of sodium–proton transport (McLean et al., 2000). Amiloride has been reported to selectively kill human malignant glioma cell lines but not primary astrocytes (Hegde et al., 2004). While amiloride reduces pHi of malignant gliomas by inhibiting isoform 1 of sodium–proton exchange (NHE1), direct acidification was shown to be cytostatic rather than cytotoxic. At cytotoxic concentrations, amiloride has multiple drug targets including inhibition of NHE1 and sodium–calciumexchange. Amiloride's glioma cytotoxicity can be explained, at least in part, by dual inhibition of NHE1 and …


Sovereignty And Cooperative Management Of Shared Water Resources In A Time Of Shrinking Availability: The Role Of International Law, Stephen C. Mccaffrey Dec 2010

Sovereignty And Cooperative Management Of Shared Water Resources In A Time Of Shrinking Availability: The Role Of International Law, Stephen C. Mccaffrey

McGeorge School of Law Other Faculty Works

It is a commonplace today that per capita availability of fresh water is shrinking. In addition, it is well known that some 60 per cent of global freshwater flows are contained in the 263 river basins that are shared by two or more countries, and that around 40 per cent of the human population lives in these international basins. These facts underscore the necessity of cooperation between states sharing fresh water, whether it is on the surface or underground. And yet internal political forces often lead countries to maximize their use of shared water resources without considering adequately the needs …


Columbia Chronicle (12/06/2010), Columbia College Chicago Dec 2010

Columbia Chronicle (12/06/2010), Columbia College Chicago

Columbia Chronicle

Student newspaper from December 6, 2010 entitled The Columbia Chronicle. This issue is 44 pages and is listed as Volume 46, Number 14. Cover story: "Smith visits, speaks volumes" Editor-in-Chief: Spencer Roush


Lanthorn, Vol. 45, No. 29, December 6, 2010, Grand Valley State University Dec 2010

Lanthorn, Vol. 45, No. 29, December 6, 2010, Grand Valley State University

Volume 45, July 8, 2010 - June 9, 2011

Lanthorn is Grand Valley State's student newspaper, published from 1968 to the present.


Thinking Differently: Developing A Fall Risk Assessment For The Emergency Department Setting, Carissa K. Fauks Dec 2010

Thinking Differently: Developing A Fall Risk Assessment For The Emergency Department Setting, Carissa K. Fauks

Theses and Graduate Projects

When a patient falls in the hospital it ends up being costly for both the patient and the hospital. Having an awareness of risk factors that lead to an increase in patient falls becomes very important for all nursing staff. However, the contributing factors are not the same for every department in a hospital. The focus of this proposal is the development of a fall assessment that is specific to the emergency department. Age, cognition, elimination, physical mobility, and medications were the risk factors determined to be most important after a review of the literature. Once the fall assessment scale …


Reconstructability Analysis Of Epistasis, Martin Zwick Dec 2010

Reconstructability Analysis Of Epistasis, Martin Zwick

Complex Systems Faculty Publications and Presentations

The literature on epistasis describes various methods to detect epistatic interactions and to classify different types of epistasis. Reconstructability analysis (RA) has recently been used to detect epistasis in genomic data. This paper shows that RA offers a classification of types of epistasis at three levels of resolution (variable-based models without loops, variable-based models with loops, state-based models). These types can be defined by the simplest RA structures that model the data without information loss; a more detailed classification can be defined by the information content of multiple candidate structures. The RA classification can be augmented with structures from related …


Differences In Student Knowledge And Perception Of Learning Experiences Among Non-Traditional Students In Blended And Face-To-Face Classroom Delivery, Julieta A. Arano-Ocuaman Dec 2010

Differences In Student Knowledge And Perception Of Learning Experiences Among Non-Traditional Students In Blended And Face-To-Face Classroom Delivery, Julieta A. Arano-Ocuaman

Dissertations

The purpose of this study was to examine the efficacy of traditional and blended (partially online and partially face-to-face) course delivery methods. This study further examined the impact of using technology to improve student learning by providing meaningful learning in the areas of content delivery, communication and collaboration, evaluation and feedback, and personal learning experiences. Non-traditional students enrolled in an elementary statistics course either delivered as a traditional course or a blended course participated in the study. It was hypothesized that students enrolled in the blended course would perform better and prefer this method of delivery compared to students enrolled …


College Voice Vol. 35 No. 9, Connecticut College Dec 2010

College Voice Vol. 35 No. 9, Connecticut College

2010-2011

No abstract provided.


The Effects Of Whole Body Vibration On Strength Gains In The Bench Press, The Back Squat, And The Power Clean In Division I Football Players, Kelly S. Poppinga Dec 2010

The Effects Of Whole Body Vibration On Strength Gains In The Bench Press, The Back Squat, And The Power Clean In Division I Football Players, Kelly S. Poppinga

Theses and Dissertations

The purpose of this study was to determine if whole body vibration effects strength gains in the bench press, the back squat, and the power clean in division 1 football players. Thirty-one NCAA Division 1 male football players volunteered for this study and were randomly assigned to a control group (C=16) or one of two vibration groups (V1=7, V2=8). Subjects followed the training program for eight weeks. A pre-test, mid-test, and post-test one repetition max was measured at 0, 4, and 8 weeks for the bench press, the back squat, and the power clean. A 3x3 factorial ANOVA revealed varied …


The Relationship Between Family Recreation And Relatedness In Children And Their Families, Kristen Berrett Dec 2010

The Relationship Between Family Recreation And Relatedness In Children And Their Families, Kristen Berrett

Theses and Dissertations

The purpose of this study was to provide insight into the factors contributing to relatedness in children, specifically family recreation, and to look at relatedness between family members (family relatedness), and whether or not family recreation makes a contribution to this construct. Two instruments were used to collect data for this study. The Family Leisure Activity Profile (FLAP) measured family recreation involvement and satisfaction, and the Activity-Feelings States Scales (AFS) measured child and family relatedness. The sample included elementary school children between the ages of 6 years and 12 years (n1=405), and the parents of those children (n2=405). The data …


Usa V. Jerry Whitfield Dec 2010

Usa V. Jerry Whitfield

2010 Decisions

USDC for the District of New Jersey


Rocky Mountain Power V. Jensen Clerk's Record V. 3 Dckt. 37998 Dec 2010

Rocky Mountain Power V. Jensen Clerk's Record V. 3 Dckt. 37998

Idaho Supreme Court Records & Briefs, All

No abstract provided.


Some Results For Integral Inclusions Of Volterra Type In Banach Spaces, Ravi P. Agarwal, Mouffak Benchohra, Juan Jose Nieto, Abdelghani Ouahab Dec 2010

Some Results For Integral Inclusions Of Volterra Type In Banach Spaces, Ravi P. Agarwal, Mouffak Benchohra, Juan Jose Nieto, Abdelghani Ouahab

Mathematics and System Engineering Faculty Publications

We first present several existence results and compactness of solutions set for the following Volterra type integral inclusions of the form: y(t) ∈ ∫0 t a(t-s)[Ay(s)+F(s,y(s)) ]ds,a.e.t ∈ J, where J=[ 0,b ], A is the infinitesimal generator of an integral resolvent family on a separable Banach space E, and F is a set-valued map. Then the Filippov's theorem and a Filippov-Waewski result are proved.


Grand Valley Forum, Volume 035, Number 15, December 6, 2010, Grand Valley State University Dec 2010

Grand Valley Forum, Volume 035, Number 15, December 6, 2010, Grand Valley State University

2010-2011, Volume 35

Grand Valley Forum is Grand Valley State's faculty and staff newsletter, published from 1976 to the present.


Nebraska's Centennial Mall -- Where You Go To Grow: An Integrated Marketing Communications Plan, Secret Radio, Pam Orr, Brianne Hake, Jessica Simpson, Stephanie Scharf, Charles Wetzel, Stacy C. James Dec 2010

Nebraska's Centennial Mall -- Where You Go To Grow: An Integrated Marketing Communications Plan, Secret Radio, Pam Orr, Brianne Hake, Jessica Simpson, Stephanie Scharf, Charles Wetzel, Stacy C. James

College of Journalism and Mass Communications: Student Advertising Projects

Situation Analysis
Nebraska’s Centennial Mall, extending from the State Capitol seven blocks north on what would be 15th Street, serves as a scenic connection between Nebraska’s iconic State Capitol and the University of Nebraska-Lincoln. The Mall is currently in a state of disrepair, but a restoration project will soon begin. Our task is to implement a statewide awareness campaign to encourage all Nebraskans to visit and take pride in Nebraska’s Centennial Mall. In essence, the new Mall is the front yard and primary entrance to the State Capitol and should be viewed and appreciated as a symbol to the state …


Florida Sentinel Bulletin, December 6, 2010, Gwen Hayes Dec 2010

Florida Sentinel Bulletin, December 6, 2010, Gwen Hayes

Florida Sentinel Bulletin Collection

The December 6, 2010, issue of the Florida Sentinel Bulletin.


Feedback Linearization Internal Control For The Unified Power Flow Controller, Keyou Wang, Mariesa L. Crow Dec 2010

Feedback Linearization Internal Control For The Unified Power Flow Controller, Keyou Wang, Mariesa L. Crow

Electrical and Computer Engineering Faculty Research & Creative Works

This paper presents feedback linearization-based controller design methodology for a unified power flow controller (UPFC) to achieve rapid reference signal tracking in the internal level. Feedback linearization control (FBLC) is a nonlinear technique based on differential geometry theory and overcomes the drawback of traditional PI control linearizing at one specific operating condition. FBLC is applied on UPFC dynamic model via an appropriate coordinate transformation and LQR control is then applied on the transferred linear system. the proposed control is validated on the IEEE 118-bus system with full-order generator and network models. ©2010 IEEE.


Bjc Today Dec 2010

Bjc Today

BJC Today

No abstract provided.


The Murray Ledger And Times, December 6, 2010, The Murray Ledger And Times Dec 2010

The Murray Ledger And Times, December 6, 2010, The Murray Ledger And Times

The Murray Ledger & Times

No abstract provided.


Binding Ligand Prediction For Proteins Using Partial Matching Of Local Surface Patches, Lee Sael, Daisuke Kihara Dec 2010

Binding Ligand Prediction For Proteins Using Partial Matching Of Local Surface Patches, Lee Sael, Daisuke Kihara

Department of Biological Sciences Faculty Publications

Functional elucidation of uncharacterized protein structures is an important task in bioinformatics. We report our new approach for structure-based function prediction which captures local surface features of ligand binding pockets. Function of proteins, specifically, binding ligands of proteins, can be predicted by finding similar local surface regions of known proteins. To enable partial comparison of binding sites in proteins, a weighted bipartite matching algorithm is used to match pairs of surface patches. The surface patches are encoded with the 3D Zernike descriptors. Unlike the existing methods which compare global characteristics of the protein fold or the global pocket shape, the …