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2010

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Mitofusin 2 Is Necessary For Transport Of Axonal Mitochondria And Interacts With The Miro/Milton Complex, Albert Misko, Siriui Jiang, Iga Wegorzewska, Jeffrey Milbrandt, Robert H. Baloh Jan 2010

Mitofusin 2 Is Necessary For Transport Of Axonal Mitochondria And Interacts With The Miro/Milton Complex, Albert Misko, Siriui Jiang, Iga Wegorzewska, Jeffrey Milbrandt, Robert H. Baloh

Open Access Publications

No abstract provided.


Roles Of Membrane Trafficking In Nerve Repair And Regeneration, Elizabeth Tuck, Valeria Cavalli Jan 2010

Roles Of Membrane Trafficking In Nerve Repair And Regeneration, Elizabeth Tuck, Valeria Cavalli

Open Access Publications

No abstract provided.


Spot: A Web-Based Tool For Using Biological Databases To Prioritize Snps After A Genome-Wide Association Study, Scott F. Saccone, Raphael Bolze, Prasanth Thomas, Jiaxi Quan, Gaurang Mehta, Ewa Deelman, Jay A. Tischfield, John P. Rice Jan 2010

Spot: A Web-Based Tool For Using Biological Databases To Prioritize Snps After A Genome-Wide Association Study, Scott F. Saccone, Raphael Bolze, Prasanth Thomas, Jiaxi Quan, Gaurang Mehta, Ewa Deelman, Jay A. Tischfield, John P. Rice

Open Access Publications

No abstract provided.


The Arf Tumor Suppressor Regulates Bone Remodeling And Osteosarcoma Development In Mice, Daniel A. Rauch, Michelle A. Hurchla, John C. Harding, Hongju Deng, Lauren K. Shea, Mark C. Eagleton, Stefan Niewiesk, Michael D. Lairmore, David Piwnica-Worms, Thomas J. Rosol, Jason D. Weber, Lee Ratner, Katherine N. Weilbaecher Jan 2010

The Arf Tumor Suppressor Regulates Bone Remodeling And Osteosarcoma Development In Mice, Daniel A. Rauch, Michelle A. Hurchla, John C. Harding, Hongju Deng, Lauren K. Shea, Mark C. Eagleton, Stefan Niewiesk, Michael D. Lairmore, David Piwnica-Worms, Thomas J. Rosol, Jason D. Weber, Lee Ratner, Katherine N. Weilbaecher

Open Access Publications

No abstract provided.


Melanoma Differentiation-Associated Gene 5 (Mda5) Is Involved In The Innate Immune Response To Paramyxoviridae Infection In Vivo, Leonid Gitlin, Loralyn Benoit, Christina Song, Marina Cella, Susan Gilfillan, Michael J. Holtzman, Marco Colonna Jan 2010

Melanoma Differentiation-Associated Gene 5 (Mda5) Is Involved In The Innate Immune Response To Paramyxoviridae Infection In Vivo, Leonid Gitlin, Loralyn Benoit, Christina Song, Marina Cella, Susan Gilfillan, Michael J. Holtzman, Marco Colonna

Open Access Publications

No abstract provided.


Nik Stabilization In Osteoclasts Results In Osteoporosis And Enhanced Inflammatory Osteolysis, Chang Yang, Kathleen Mccoy, Jennifer L. Davis, Marc Schmidt-Supprian, Yoshiteru Sasaki, Roberta Faccio, Deborah Veis Novack Jan 2010

Nik Stabilization In Osteoclasts Results In Osteoporosis And Enhanced Inflammatory Osteolysis, Chang Yang, Kathleen Mccoy, Jennifer L. Davis, Marc Schmidt-Supprian, Yoshiteru Sasaki, Roberta Faccio, Deborah Veis Novack

Open Access Publications

No abstract provided.


Ips-1 Is Essential For The Control Of West Nile Virus Infection And Immunity, Mehul S. Suthar, Daphne Y. Ma, Sunil Thomas, Jennifer M. Lund, Nu Zhang, Stephane Daffis, Alexander Y. Rudensky, Michael J. Bevan, Edward A. Clark, Murali-Krishna Kaja, Michael S. Diamond, Michael Gale Jr. Jan 2010

Ips-1 Is Essential For The Control Of West Nile Virus Infection And Immunity, Mehul S. Suthar, Daphne Y. Ma, Sunil Thomas, Jennifer M. Lund, Nu Zhang, Stephane Daffis, Alexander Y. Rudensky, Michael J. Bevan, Edward A. Clark, Murali-Krishna Kaja, Michael S. Diamond, Michael Gale Jr.

Open Access Publications

No abstract provided.


Coordinated Progression Through Two Subtranscriptomes Underlies The Tachyzoite Cycle Of Toxoplasma Gondii, Michael S. Behnke, John C. Wootton, Margaret M. Lehmann, Josh B. Radke, Olivier Lucas, Julie Nawas, L. David Sibley, Michael W. White Jan 2010

Coordinated Progression Through Two Subtranscriptomes Underlies The Tachyzoite Cycle Of Toxoplasma Gondii, Michael S. Behnke, John C. Wootton, Margaret M. Lehmann, Josh B. Radke, Olivier Lucas, Julie Nawas, L. David Sibley, Michael W. White

Open Access Publications

No abstract provided.


Cxcl12 Inhibits Expression Of The Nmda Receptor's Nr2b Subunit Through A Histone Deacetylase-Dependent Pathway Contributing To Neuronal Survival, J. Nicolai, S. Burbassi, J. Rubin, O. Meucci Jan 2010

Cxcl12 Inhibits Expression Of The Nmda Receptor's Nr2b Subunit Through A Histone Deacetylase-Dependent Pathway Contributing To Neuronal Survival, J. Nicolai, S. Burbassi, J. Rubin, O. Meucci

Open Access Publications

No abstract provided.


Consuming Cassava As A Staple Food Places Children 2-5 Years Old At Risk For Inadequate Protein Intake, An Observational Study In Kenya And Nigeria, Kevin Stephenson, Rachel Amthor, Sally Mallowa, Rhoda Nungo, Busie Maziya-Dixon, Simon Gichuki, Ada Mbanaso, Mark Manary Jan 2010

Consuming Cassava As A Staple Food Places Children 2-5 Years Old At Risk For Inadequate Protein Intake, An Observational Study In Kenya And Nigeria, Kevin Stephenson, Rachel Amthor, Sally Mallowa, Rhoda Nungo, Busie Maziya-Dixon, Simon Gichuki, Ada Mbanaso, Mark Manary

Open Access Publications

No abstract provided.


State-Dependent Electrostatic Interactions Of S4 Arginines With E1 In S2 During Kv7.1 Activation, Dick Wu, Kelli Delaloye, Mark A. Zaydman, Ali Nekouzadeh, Yoram Rudy, Jianmin Cui Jan 2010

State-Dependent Electrostatic Interactions Of S4 Arginines With E1 In S2 During Kv7.1 Activation, Dick Wu, Kelli Delaloye, Mark A. Zaydman, Ali Nekouzadeh, Yoram Rudy, Jianmin Cui

Open Access Publications

No abstract provided.


Gamma-Secretase Composed Of Ps1/Pen2/Aph1a Can Cleave Notch And Amyloid Precursor Protein In The Absence Of Nicastrin, Guojun Zhao, Zhenyi Liu, Ma. Xenia G. Ilagan, Raphael Kopan Jan 2010

Gamma-Secretase Composed Of Ps1/Pen2/Aph1a Can Cleave Notch And Amyloid Precursor Protein In The Absence Of Nicastrin, Guojun Zhao, Zhenyi Liu, Ma. Xenia G. Ilagan, Raphael Kopan

Open Access Publications

No abstract provided.


Developmental Origin Of Prebötzinger Complex Respiratory Neurons, Paul A. Gray, John A. Hayes, Guang Y. Ling, Isabel Llona, Srinivasan Tupal, Maria C.D. Picardo, Sarah E. Ross, Tsutomu Hirata, Joshua G. Corbin, Jaime Eugenín, Christopher A. Del Negro Jan 2010

Developmental Origin Of Prebötzinger Complex Respiratory Neurons, Paul A. Gray, John A. Hayes, Guang Y. Ling, Isabel Llona, Srinivasan Tupal, Maria C.D. Picardo, Sarah E. Ross, Tsutomu Hirata, Joshua G. Corbin, Jaime Eugenín, Christopher A. Del Negro

Open Access Publications

No abstract provided.


Mhc Class I–Deficient Natural Killer Cells Acquire A Licensed Phenotype After Transfer Into An Mhc Class I–Sufficient Environment, Julie M. Elliott, Joseph A. Wahle, Wayne M. Yokoyama Jan 2010

Mhc Class I–Deficient Natural Killer Cells Acquire A Licensed Phenotype After Transfer Into An Mhc Class I–Sufficient Environment, Julie M. Elliott, Joseph A. Wahle, Wayne M. Yokoyama

Open Access Publications

No abstract provided.


Peripheral Cd103+ Dendritic Cells Form A Unified Subset Developmentally Related To Cd8Α+ Conventional Dendritic Cells, Brian T. Edelson, Wumesh Kc, Richard Juang, Masako Kohyama, Loralyn A. Benoit, Paul A. Klekotka, Clara Moon, Jörn C. Albring, Wataru Ise, Drew G. Michael, Deepta Bhattacharya, Thaddeus S. Stappenbeck, Michael J. Holtzman, Sun-Sang J. Sung, Theresa L. Murphy, Kai Hildner, Kenneth M. Murphy Jan 2010

Peripheral Cd103+ Dendritic Cells Form A Unified Subset Developmentally Related To Cd8Α+ Conventional Dendritic Cells, Brian T. Edelson, Wumesh Kc, Richard Juang, Masako Kohyama, Loralyn A. Benoit, Paul A. Klekotka, Clara Moon, Jörn C. Albring, Wataru Ise, Drew G. Michael, Deepta Bhattacharya, Thaddeus S. Stappenbeck, Michael J. Holtzman, Sun-Sang J. Sung, Theresa L. Murphy, Kai Hildner, Kenneth M. Murphy

Open Access Publications

No abstract provided.


Role Of Abl Kinase And The Wave2 Signaling Complex In Hiv-1 Entry At A Post-Hemifusion Step, Brooke Harmon, Nancy Campbell, Lee Ratner Jan 2010

Role Of Abl Kinase And The Wave2 Signaling Complex In Hiv-1 Entry At A Post-Hemifusion Step, Brooke Harmon, Nancy Campbell, Lee Ratner

Open Access Publications

No abstract provided.


Neurofibromatosis-1 Regulates Neuroglial Progenitor Proliferation And Glial Differentiation In A Brain Region-Specific Manner, Da Yong Lee, Tu-Hsueh Yeh, Ryan J. Emnett, Crystal R. White, David H. Gutmann Jan 2010

Neurofibromatosis-1 Regulates Neuroglial Progenitor Proliferation And Glial Differentiation In A Brain Region-Specific Manner, Da Yong Lee, Tu-Hsueh Yeh, Ryan J. Emnett, Crystal R. White, David H. Gutmann

Open Access Publications

No abstract provided.


"It's Not Easy Being Green": Local Initiatives, Preemption Problems, And The Market Participant Exception, Michael Burger Jan 2010

"It's Not Easy Being Green": Local Initiatives, Preemption Problems, And The Market Participant Exception, Michael Burger

Sabin Center for Climate Change Law

This Article considers whether the market participant exception should be interpreted to exempt local climate change and sustainability initiatives from the "ceilings" imposed by existing environmental laws and pending federal climate change legislation. In the decades-long absence of federal action on climate change, local governments – along with the states – positioned themselves at the forefront of climate change and sustainability planning. In fact, state and local actions account for most of the nation's greenhouse gas reduction efforts to date. Yet, front-running localities are being limited by a preemption doctrine that fails to account for both the motives behind their …


“Everything Has Changed”: Narratives Of The Vietnamese American Community In Post-Katrina Mississippi, Yoosun Park, Joshua Miller, Bao Chau Van Jan 2010

“Everything Has Changed”: Narratives Of The Vietnamese American Community In Post-Katrina Mississippi, Yoosun Park, Joshua Miller, Bao Chau Van

School for Social Work: Faculty Publications

In this qualitative study of the Vietnamese American community of Biloxi, Mississippi, conducted three years after Katrina, we attended not only to individual experiences but to the relationship of individuals to their collective and social worlds. The interlocked relationship of individual and collective loss and recovery are clearly demonstrated in respondents’ narratives. The neighborhood and community of Little Saigon was significant not only as a symbolic source of identity but as a protected and familiar space of residence, livelihood, and social connections. The post-Katrina changes in the neighborhood are, in multiple ways, changing participants’ experience of and relationship to their …


A Few Steps Forward In The Process Of Looking Back: Setting Parameters For A Self-Study Of Administrative And Program Development Work Over 18 Years, Deborah Roose Jan 2010

A Few Steps Forward In The Process Of Looking Back: Setting Parameters For A Self-Study Of Administrative And Program Development Work Over 18 Years, Deborah Roose

Faculty & Staff Scholarship

Most self-studies focus on an individual or several teacher educators. Although there have been self-studies undertaken by teacher education administrators, there is relatively little research available that focuses specifically on administrator’s program development work in teacher education. This self-study examines one teacher education administrator’s program development work over a period of 18 years and in two institutions. Data comes from entries from a professional journal/log kept during those years. A framework consisting of emergent categories and sub-categories was developed for analysis. Initial findings suggest there is a complexity of and multiple roles that are influenced by outside forces. In terms …


The American Inquisition: Sentencing After The Federal Guidelines, Ricardo J. Bascuas Jan 2010

The American Inquisition: Sentencing After The Federal Guidelines, Ricardo J. Bascuas

Articles

No abstract provided.


Regulation Of Peripheral Nerve Regeneration By The Mtor Pathway, Namiko Abe Jan 2010

Regulation Of Peripheral Nerve Regeneration By The Mtor Pathway, Namiko Abe

All Theses and Dissertations (ETDs)

While neurons in the central nervous system: CNS) have limited capacity for regrowth after damage, neurons in the peripheral nervous system: PNS) have a robust ability to regenerate their axons following injury. Successful regeneration depends upon both extrinsic cues in the environment and the activation of intrinsic mechanisms to promote regrowth. A number of inhibitory molecules in the CNS environment that prevent axonal regrowth have been identified, but less is known regarding the signaling mechanisms that regulate regenerative ability in PNS neurons. Here, we explored multiple components of injury signaling in the PNS, including the retrograde transport of local axonal …


Torts As Wrongs, John C.P. Goldberg, Benjamin C. Zipursky Jan 2010

Torts As Wrongs, John C.P. Goldberg, Benjamin C. Zipursky

Faculty Scholarship

Torts scholars hold different views on why tort law shifts costs from plaintiffs to defendants. Some invoke notions of justice, some efficiency, and some compensation. Nearly all seem to agree, however, that tort law is about the allocation of losses. This Article challenges the widespread embrace of loss-based accounts as fundamentally misguided. It is wrongs not losses that lie at the foundation of tort law. Tort suits are about affording plaintiffs an avenue of civil recourse against those who have wronged them. Although torts were once routinely understood as wrongs, since Holmes’s time, tort scholars have tended to suppose that …


Managing Health Care In A Libyan Public Hospital: A Case Study, Alexandria K. Osborne Jan 2010

Managing Health Care In A Libyan Public Hospital: A Case Study, Alexandria K. Osborne

Walden Dissertations and Doctoral Studies

Libyan citizens who can afford private health care are opting out of the public health care system. They have a perception that the quality of public health care has deteriorated. The negative perceptions have resulted in a lack of trust by many of Libyan's citizens in the Libyan public health care system and consequently to unequal access to quality health care. The purpose of this study was to identify the factors that have led to the negative perceptions and mistrust. The conceptual support for the study was based on a construct of trust that defines trust as the state of …


The Relationship Between Psychological Well-Being And Perceived Wellness In Graduate-Level Counseling Students, Michel Renee Harris Jan 2010

The Relationship Between Psychological Well-Being And Perceived Wellness In Graduate-Level Counseling Students, Michel Renee Harris

Walden Dissertations and Doctoral Studies

It is imperative that those who provide personal therapy to others be well-adjusted in their personal and professional lives and possess a keen and accurate perception of wellness. Yet, persons drawn to careers in counseling often have unresolved psychological issues. Counselor education programs should have a systematic way to evaluate and improve wellness in their students. Studies addressing the well-being of counselors-in-training, their perception of wellness, and their need for self-care are lacking in the professional literature. This study, therefore, examined the relationship between psychological well-being and perceived wellness in a sample (N = 97) of graduate students in a …


Using Globally Significant Children's Literature To Increase Fourth-Grade Students' Global Attitudes And Intercultural Sensitivity, Tonya Salisbury Jan 2010

Using Globally Significant Children's Literature To Increase Fourth-Grade Students' Global Attitudes And Intercultural Sensitivity, Tonya Salisbury

Walden Dissertations and Doctoral Studies

It is vital for future generations to clearly grasp what it means to be global citizens in order for them to be successful and for America to maintain its status as a world leader. The purpose of this mixed-method study was to measure and describe the growth of global attitudes and intercultural sensitivity that fourth-grade students acquire through reading and discussing globally significant children's literature which honors and celebrates diversity worldwide, in terms of culture, race, language, religion, and social status. According to Rosenblatt's transactional theory, readers experience aesthetic transactions with the text leading to an understanding of the world …


Social Capital Variables As Predictors Of Hiv Risk-Taking Behaviors Among Sub-Saharan African Immigrants In The United States, Gbadebo Ogundiran Ogungbade Jan 2010

Social Capital Variables As Predictors Of Hiv Risk-Taking Behaviors Among Sub-Saharan African Immigrants In The United States, Gbadebo Ogundiran Ogungbade

Walden Dissertations and Doctoral Studies

Vulnerable populations, including immigrants, are often at risk for human immunodeficiency virus (HIV) infection because of their risk-taking behaviors. This study investigated risk-taking behavior for HIV infection among Sub-Saharan African (SSA) immigrants in United States. Using social capital as a theoretical foundation, the study aimed to address the question, is there any association between social capital assets of educational opportunity, employment, and eligibility for social assistance and HIV risk-taking behavior, defined as condom use before sex (CUBS) among SSA immigrant in the U.S? Potential participants were recruited through religious and social organizations in a southwestern US state. The survey generated …


The Relationship Between Campus Climate And The Teaching Of Critical Thinking Skills In Community College Classrooms, Thomas C. Simon Jan 2010

The Relationship Between Campus Climate And The Teaching Of Critical Thinking Skills In Community College Classrooms, Thomas C. Simon

Walden Dissertations and Doctoral Studies

Although critical thinking skills are important for all citizens participating in a democratic society, many community college students appear to lack these skills. This study addressed the apparent lack of research relating critical thinking instruction to campus climate. Critical thinking theory and Moos's organizational climate theory served as the theoretical foundation. The relationship between faculty's perceptions of three campus climate factors and their use of five critical thinking instructional techniques in the classroom was analyzed in this quantitative study. An online instrument based on the School-Level Environment Questionnaire (SLEQ) to measure campus climate and a researcher-designed measure of critical thinking …


Perceived Attributes And Organizational Support Influencing Course Management System Adopter Status In Historically Black Colleges And Universities, Gayla Spooner Keesee Jan 2010

Perceived Attributes And Organizational Support Influencing Course Management System Adopter Status In Historically Black Colleges And Universities, Gayla Spooner Keesee

Walden Dissertations and Doctoral Studies

The rapid growth of online learning fueled by technologies including course management systems (CMS) has transformed the traditional educational landscape. Little research shows why faculty members at Historically Black Colleges and Universities (HBCUs) have been slow to adopt this new teaching paradigm. This quantitative, nonexperimental study utilized Rogers's diffusion of innovation theory as the theoretical base. Research questions explored faculty perceptions of the CMS's attributes (relative advantage, compatibility, complexity, trialability, observability) and organizational support (policies, procedures, and norms) in order to predict adopter status. The study used a convenience sample of 137 full-time faculty from 3 public and 2 private …


The Probability Of Actual Bias, Objective Standards, And Pandora's Box - Caperton V. A. T. Massey Coal Company, Leon D. Lazer Honorable Jan 2010

The Probability Of Actual Bias, Objective Standards, And Pandora's Box - Caperton V. A. T. Massey Coal Company, Leon D. Lazer Honorable

Touro Law Review

No abstract provided.