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April 8, 2010, James Madison University

The Breeze, 2010-2019

The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.

The Murray Ledger And Times, April 8, 2010, The Murray Ledger And Times

The Murray Ledger & Times

No abstract provided.

Dihydropyran Formation By A Two Step Process, James Zachary Wright

Undergraduate Honors Thesis Collection

The 2, 6-disubstitued dihydropyran is produced by a two step process, involving a Suzuki Miyaura Cross Coupling reaction followed by anintramolecular ring closing Michael Addition reaction. In this project a vinyl boronic acid, 6-(2-phenylethenyl)-2-hydroxy-I,2-oxaborole, was coupled with cis-ethyl-iodo-acrylate to yield ethyI 2E, 4Z, 8E-9-phenyl-7-hydroxy-2, 4, 8-nonatrienoate, which is capable of undergoing an intramolecular Michael addition to form the dihydropyran. The geometry of the cis enolate and the conjugated double bonds of the coupled product are such that under basic conditions a Michael addition is feasible. Throughout the project, the reaction conditions for high yields of Suzuki product were determined. Dihydropyrans …

The Pan American (2010-04-08), Brian Silva

UTPA Archives - The Pan American Newspaper

Vol. 66, No. 24

The Comment, April 8, 2010, Bridgewater State College

The Comment

No abstract provided.

The Missouri Miner, April 8, 2010

The Missouri Miner Newspaper

No abstract provided.

The Alestle - Vol. 62 No. 29 - 04/08/2010, Southern Illinois University Edwardsville

The Alestle

Vol. 62 No. 29

The Loss Of Species: Mangrove Extinction Risk And Geographic Areas Of Global Concern, Beth A. Polidoro, Kent E. Carpenter, Lorna Collins, Norman C. Duke, Aaron M. Ellison, Joanna C. Ellison, Elizabeth J. Farnsworth, Edwino S. Fernando, Kandasamy Kathiresan, Nico E. Koedam, Suzanne R. Livingstone, Toyohiko Miyagi, Gregg E. Moore, Vien Ngoc Nam, Jin Eong Ong, Jurgenne H. Primavera, Serverino G. Salmo, Jonnell C. Sanciango, Sukristijono Sukardjo, Yamin Wang, Jean Wan Hong Yong

Biological Sciences Faculty Publications

Mangrove species are uniquely adapted to tropical and subtropical coasts, and although relatively low in number of species, mangrove forests provide at least US $1.6 billion each year in ecosystem services and support coastal livelihoods worldwide. Globally, mangrove areas are declining rapidly as they are cleared for coastal development and aquaculture and logged for timber and fuel production. Little is known about the effects of mangrove area loss on individual mangrove species and local or regional populations. To address this gap, species-specific information on global distribution, population status, life history traits, and major threats were compiled for each of the …

2010.04.08 - Board Of Trustees Meeting Minutes, Northeastern Illinois University Board Of Trustees

Board of Trustees - 2010

Meeting materials for the NEIU Board of Trustees

Minutes From The April 8, 2010 Meeting Of The University Of Montana Faculty, University Of Montana--Missoula. Faculty

University of Montana Faculty Senate Meeting Minutes

Meeting minutes from the April 8, 2010 meeting of the University of Montana faculty.

Living On Autopilot: How Your Brain Thinks For You, Andrea Stathopoulos '10

Honor Scholar Theses

One way in which humans are set apart from other animals is by our impressive intellectual capacities. Humans are commonly considered to be true masters of rational, conscious control over our actions. However, that feeling of control may be mostly illusory. Accumulating evidence suggests that unconscious cognitive processes can account for much of human behavior. Homeostasis is a clear example of the evolutionary benefit of automation, allowing valuable energy and limited attention to be diverted elsewhere. I instead want to focus on the automaticity of more complicated behaviors, ones that are typically thought to require a large amount of cognitive …

An Economic Analysis Of Title I Of The Genetic Nondis, Elizabeth Cozzi '10

Honor Scholar Theses

No abstract provided.

The Effects Of Gdf8 And Activin A On Muscle Atrophy, Amy Sato '10

Honor Scholar Theses

Muscle atrophy and weakening are major health care concerns. For instance sarcopenia, which is a condition of extreme muscle loss and weakening due to aging, was estimated to have cost over 18.5 billion for the year 2000 in the US (Dirks & Leeuwenburgh, 2005). Abilities that depend upon muscle quality like strength, functional mobility, and balance are all key components for how people evaluate their self-rated health (SRH) and quality of life (QoL) (Ozcan et al., 2005; Sirola et al., 2010). Interestingly, SRH and QoL also serve as strong predictors for institutionalization, disability, and mortality for elderly populations (Marzetti & …

Lens: Alternative Realities Including Our Own., Shelby Vorndran '10

Honor Scholar Theses

No abstract provided.

The Inkwell, Armstrong Atlantic State University

The Inkwell

No abstract provided.

Perifosine, A Novel Akt Inhibitor Induces Apoptosis, Cell Cycle Arrest And Has A Chemo-Sensitizing Effect In Medulloblastoma Cell Lines, Anil Kumar

Theses and Dissertations

Primary central nervous system (CNS) tumors are the most common solid tumors found in children. While surgery and radiotherapy still remain the standard treatment modalities in pediatric brain tumors, chemotherapy also has an important part in the management of these tumors. However, most of the available chemotherapeutic drugs have suboptimal effectiveness. Deregulation of various pro-apoptotic and anti-apoptotic pathways has been cited as a major mechanism underlying this drug resistance. The role of various serine threonine kinases, including Akt kinases, in promoting drug resistance is being extensively studied in various cancers. A complete understanding of the molecular mechanisms that underlie drug …

Splicing Systems For Studying Signaling To The Spliceosome, Hercules S. Apostolatos

USF Tampa Graduate Theses and Dissertations

Alternative splicing is a major contributing factor to protein diversity. The human genome project validated that there are about 25,000 genes, but over 100,000 proteins. Genes contain numerous exons that are specifically regulated; thus, elucidating alternative splicing mechanisms of pre-mRNAs is an immense undertaking. Two basic tools are used to study this mammoth task. For in vitro studies, usually in vitro transcription followed by splicing assays is used. For in vivo studies, the main technique is the construction of minigenes. These techniques enable one to study the mechanisms/conditions that explain an exon's inclusion or exclusion in the mature mRNA.

In …

Recruit-Recruit Interactions, Density-Dependent Processes And Population Persistence In The Eastern Oyster, Crassostrea Virginica, Am Knights, K Walters

School of Biological and Marine Sciences

The supply and successful settlement of larvae is vital for the development and persistence of populations of many marine species. Strongly influenced by hydrodynamic processes, the rate of supply affects the interaction between recruits. Population structure is determined by densityindependent mortality when recruitment is limited, and by density-dependent mortality when saturated; however, the extent to which these processes determine population structure remains unclear. The relationship between recruitment and density-dependent processes in population persistence was examined in South Carolina for the eastern oyster Crassostrea virginica. Over a range of recruit densities, the resultant change in population structure was compared at locations …

Unamuno's Concept Of The Tragic, Ernesto O. Hernandez

USF Tampa Graduate Theses and Dissertations

This thesis focuses in presenting Miguel de Unamuno’s concept of the tragic. Historically this concept has suffered various changes of meaning and application. If successful the project shall provide the distinct connotation, features, and characteristics that Unamuno attributes to the tragic. His special treatment of the tragic harnesses a way for the will to become aware of its existential condition. This awakening of consciousness evokes an arousal of dichotomies that the will must confront. Faith against reason, religion against science, heart against intellect, are amongst these conflicting predicaments. The will’s constant struggle between these opposing forces constitutes for Unamuno the …

What The Surprising Failure Of Data Anonymization Means For Law And Policy, Paul Ohm

High Tech Law Institute Events

Paul Ohm is an Associate Professor of Law at the University of Colorado Law School. He writes in the areas of information privacy, computer crime law, intellectual property, and criminal procedure. Through his scholarship and outreach, Professor Ohm is leading efforts to build new interdisciplinary bridges between law and computer science. Before becoming a law professor, Professor Ohm served as a federal prosecutor for the U.S. Department of Justice in the computer crimes unit. Before law school, he worked as a computer programmer and network systems administrator.

6th Annual Undergraduate Research Conference Winners, Missouri University Of Science And Technology

Undergraduate Research Conference at Missouri S&T

No abstract provided.

The Lethal Giant Larvae Tumour Suppressor Mutation Requires Dmyc Oncoprotein To Promote Clonal Malignancy, Francesca Froldi, Marcello Ziosi, Flavio Garoia, Andrea Pession, Nicola A. Grzeschik, Paola Bellosta, Dennis Strand, Helena E. Richardson, Annalisa Pession, Daniela Grifoni

Publications and Research

Background Neoplastic overgrowth depends on the cooperation of several mutations ultimately leading to major rearrangements in cellular behaviour. Precancerous cells are often removed by cell death from normal tissues in the early steps of the tumourigenic process, but the molecules responsible for such a fundamental safeguard process remain in part elusive. With the aim to investigate the molecular crosstalk occurring between precancerous and normal cells in vivo, we took advantage of the clonal analysis methods that are available in Drosophila for studying the phenotypes due to lethal giant larvae (lgl) neoplastic mutation induced in different backgrounds and tissues. Results We …

Family Factors As A Modifier Of Individual Differences In Children With Higher Functioning Autism And Their Families, Nicole Elyse Zahka

Open Access Dissertations

This study investigated the impact of family factors on individual differences in the social and emotional development of children with autism and their families. Based on the modifier model hypothesis suggested by Mundy, Henderson, Inge, and Coman (2007), family factors may serve as a modifier that contributes to the variability in the phenotypic presentation of children with higher functioning autism. Results indicated that Expressed Emotion (EE) was associated with parent-reported hyperactivity and anxiety in children and adolescents. Family cohesion was associated with parent-reported aggression and depression. These results differed for typically developing and HFA children; higher EE or lower cohesion …

Volume 101 Issue 21, Southwestern Oklahoma State University

The Southwestern - Archive

No abstract provided.

Modeling Growth And Telomere Dynamics In Saccharomyces Cerevisiae, Peter Olofsson, Alison A. Bertuch

Mathematics Faculty Research

A general branching process is proposed to model a population of cells of the yeast Saccharomyces cerevisiae following loss of telomerase. Previously published experimental data indicate that a population of telomerase-deficient cells regain exponential growth after a period of slowing due to critical telomere shortening. The explanation for this phenomenon is that some cells engage telomerase-independent pathways to maintain telomeres that allow them to become “survivors.” Our model takes into account random variation in individual cell cycle times, telomere length, finite lifespan of mother cells, and survivorship. We identify and estimate crucial parameters such as the probability of an individual …

Easterner, Vol. 61, No. 22, April 7, 2010, Associated Students Of Eastern Washington University

Student Newspapers

This issue of the Easterner contains articles about the Friday commencement date for spring, the Associated Students (ASEWU) elections, the Science Olympiad, the consolidation and renaming of Eastern Washington University colleges, a federally funded program for first generation college students called TRiO, Creative Writing student Summer Hess' Fulbright Scholarship, an interview with track coach Stanley Kerr, Cheney artist Nancy Morrow, the track team's performance at the Al Manuel Invitational, and runner Kyle King.\

Effects Of Butyltin Exposures On Map Kinase-Dependent Transcription Regulators In Human Natural Killer Cells, Rachel J. Person, Margaret M. Whalen

Chemistry Faculty Research

Natural killer (NK) cells are a major immune defense mechanism against cancer development and viral infection. The butyltins (BTs), tributyltin (TBT) and dibutyltin (DBT), have been widely used in industrial and other applications and significantly contaminate the environment. Both TBT and DBT have been detected in human blood. These compounds inhibit the lytic and binding function of human NK cells and thus could increase the incidence of cancer and viral infections. Butyltin (BT)-induced loss of NK function is accompanied by activation of mitogen activated protein kinases (MAPKs) and decreases in expression of cell-surface and cytolytic proteins. MAPKs activate components of …

Mustang Daily, April 7, 2010

Cal Poly Student Newspaper

Student newspaper of California Polytechnic State University, San Luis Obispo, CA.

The Murray Ledger And Times, April 7, 2010, The Murray Ledger And Times

The Murray Ledger & Times

No abstract provided.

"The Crescent" Student Newspaper, April 7, 2010, George Fox University Archives

"The Crescent" Student Newspaper

Student newspaper of George Fox University.