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2010

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The Observer, Central Washington University May 2010

The Observer, Central Washington University

Student Newspaper

Student newspaper for Central Washington University for May 13-19, 2010. Vol. 85, No. 6.

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Design And Analysis Of A Compliant Mechanism Spinal Implant, Eric M. Stratton May 2010

Design And Analysis Of A Compliant Mechanism Spinal Implant, Eric M. Stratton

Theses and Dissertations

This thesis introduces and presents the modeling of a novel compliant spinal implant designed to reduce back pain and restore function to degenerate spinal disc tissues as well as provide a mechanical environment conducive to healing the tissues. The initial objectives for this device development and the focus of this work are modeling and validation of the force-deflection relationships and stress analysis. Modeling was done using the pseudo-rigid-body model to create a 3 degree of freedom mechanism for flexion-extension (forward-backward bending) and a 5 degree of freedom mechanism for lateral bending (side-to-side). These models were analyzed using the principle of …

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Mustang Daily, May 13, 2010 May 2010

Mustang Daily, May 13, 2010

Cal Poly Student Newspaper

Student newspaper of California Polytechnic State University, San Luis Obispo, CA.

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Louisiana State University Health Sciences Center - 2010 - 136th Commencement, Office Of The Registrar, Lsu Health Sciences Center-No May 2010

Louisiana State University Health Sciences Center - 2010 - 136th Commencement, Office Of The Registrar, Lsu Health Sciences Center-No

Graduation & Commencement Programs

The program for the 136th Commencement of LSU Health Sciences Center - New Orleans held May 13, 2010.

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The Word On Terrorism Threat As Terrorism Threat, Ibpp Editor May 2010

The Word On Terrorism Threat As Terrorism Threat, Ibpp Editor

International Bulletin of Political Psychology

The author discusses terrorism (and terms associated with it), considering the social rhetoric surrounding the terms as well as other potential meanings. The constraints of the words used to define these terms of terror are considered.

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Identification And Impact Of Standard Treatment Protocols On The Impairments And Activity Limitations Related To Lower Extremity Lymphedema, Kevin Robert Kunkel May 2010

Identification And Impact Of Standard Treatment Protocols On The Impairments And Activity Limitations Related To Lower Extremity Lymphedema, Kevin Robert Kunkel

Open Access Dissertations

Lower Extremity Lymphedema is a chronic condition of characterized by swelling of body part. It is typically treated with Complex Decongestive Therapy (CDT) to reduce volume. While volume reduction is the primary goal of the treatment, third party payers often require the presence of activity limitations in order to qualify for coverage. The purpose of this dissertation was to identify the types of impairments and functional limitations that occur in this population. A second goal was to determine if volume reduction from CDT is sufficient to resolve the impairments and activity limitations associated with lymphedema, or if traditional physical therapy …

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The Effects Of Early Life History On Recruitment And Early Juvenile Survival Of A Coral Reef Fish In The Florida Keys, Tauna Leigh Rankin May 2010

The Effects Of Early Life History On Recruitment And Early Juvenile Survival Of A Coral Reef Fish In The Florida Keys, Tauna Leigh Rankin

Open Access Dissertations

Processes that influence the early life stages of fishes can significantly impact population dynamics, yet they continue to be poorly understood. This dissertation examined relationships between the environment, early life history traits (ELHTs), behavior, and post-settlement survival for a coral reef fish, Stegastes partitus, in the upper Florida Keys, to elucidate how they influence juvenile demography. Otolith analysis of settlers and recruits coupled with environmental data revealed that S. partitus surviving the early juvenile period settled at larger sizes and grew slower post-settlement. Water temperature also influenced the ranges of these and other ELHTs as well as the intensity and …

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A Study Of The Biological Significance Of A Male Color Polymorphism In The Lizard Sceloporus Minor, Barry P. Stephenson May 2010

A Study Of The Biological Significance Of A Male Color Polymorphism In The Lizard Sceloporus Minor, Barry P. Stephenson

Open Access Dissertations

Males of the Mexican lizard Sceloporus minor (Phrynosomatidae) exhibit striking variation in dorsal coloration, both within and among populations, which may have arisen by sexual selection. The possible significance of this trait was investigated through a combination of observational and experimental approaches. This research revealed that males in one population (La Manzana) in NW Hidalgo exhibit three discrete color morphs (blue, yellow, red) each characterized by morphological, physiological and behavioral differences. Furthermore, these morphs can be identified by an objective approach to color assessment (spectroradiometry). In addition, males in a second population (Escalerillas) from SE San Luis Potosí were also …

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The Communicator, May 12, 2010, Bronx Community College May 2010

The Communicator, May 12, 2010, Bronx Community College

The Communicator

The Communicator newspaper published on May 12, 2010.

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Easterner, Vol. 61, No. 27, May 12, 2010, Associated Students Of Eastern Washington University May 2010

Easterner, Vol. 61, No. 27, May 12, 2010, Associated Students Of Eastern Washington University

Student Newspapers

This issue of the Easterner contains articles about a proposed Eastern Washington University (EWU) campus on Cyprus, the Spirit of the Eagle Powwow, a settlement for the death of EWU student Jerid Sturman-Camyn, changes to Dining Services offerings, planning for the Pence Union Building (PUB) remodel, increased applications to enter EWU, an interview of EWU computer science professor Thomas Capaul, a student production of "Almost, Maine", Metis artist Dylan Miner, Mixed Martial Arts event Rage in the Cage, expectations for the track team at the Big Sky Championships, and the EEEWOOS.

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Effect Of Anions On The Iron Release Pathways Of Human Serum Transferrin, Rashmi Subhash Chander Sharma May 2010

Effect Of Anions On The Iron Release Pathways Of Human Serum Transferrin, Rashmi Subhash Chander Sharma

Dissertations

Transferrin, the serum iron transport protein in humans, is used to transport 30-40 mg of iron per day through blood. The accessibility of transferrin makes it an attractive target for iron cheating therapeutic agents used in the treatment of iron overload. There is an ongoing search for ligands which can accelerate the rate of iron release, as the currently approved drug DFO has a very slow rate for iron removal. Previous studies have shown that anions can accelerate the rate of iron release. Studies on the effect of anions on the rates of iron release from C-terminal monoferric transferrin at …

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School Of Computing Students Survey May 2010, Jane Ferris May 2010

School Of Computing Students Survey May 2010, Jane Ferris

Reports

This report represents a snapshot of the students (full-time, part-time, undergraduate and postgraduate) attending the School of Computing in the DIT Kevin Street Campus in second semester of the academic session 2009/10.

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Spectator 2010-05-12, Editors Of The Spectator May 2010

Spectator 2010-05-12, Editors Of The Spectator

The Spectator

No abstract provided.

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Volume 47, Number 38: May 12, 2010, University Of North Dakota May 2010

Volume 47, Number 38: May 12, 2010, University Of North Dakota

University Letter Archive

No abstract provided.

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Hops Initiates Vacuole Docking By Tethering Membranes Before Trans-Snare Complex Assembly, Christopher M. Hickey, William Wickner May 2010

Hops Initiates Vacuole Docking By Tethering Membranes Before Trans-Snare Complex Assembly, Christopher M. Hickey, William Wickner

Dartmouth Scholarship

Vacuole homotypic fusion has been reconstituted with all purified components: vacuolar lipids, four soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins, Sec17p, Sec18p, the Rab Ypt7p, and the hexameric homotypic fusion and vacuole protein sorting complex (HOPS). HOPS is a Rab-effector with direct affinity for SNAREs (presumably via its Sec1-Munc18 homologous subunit Vps33p) and for certain vacuolar lipids. Each of these pure vacuolar proteins was required for optimal proteoliposome clustering, raising the question of which was most directly involved. We now present model subreactions of clustering and fusion that reveal that HOPS is the direct agent of tethering. The …

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Student Content Knowledge Increases After Participation In A Hands-On Biotechnology Intervention, Amber L. Bigler May 2010

Student Content Knowledge Increases After Participation In A Hands-On Biotechnology Intervention, Amber L. Bigler

Theses and Dissertations

Hands-on learning is at the heart of science learning. This study examined increased changes of student content knowledge in biology, particularly biotechnology, after a hands-on biotechnology intervention was implemented into a secondary school. A traditional learning school was selected for a control. Both teachers had participated in a biotechnology professional development program called Project Crawfish. Students from both schools took the same assessment before and after their respective units (biotechnology intervention and genetics unit), and the classroom was the unit of analysis (n=5, n=6, respectively). The assessment was compared as a whole and then divided into five components, eight questions …

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An Indecent Obsession, Aaron Mcintosh May 2010

An Indecent Obsession, Aaron Mcintosh

Theses and Dissertations

The title of my thesis is appropriately borrowed from a romance novel title, as my work proposes to mine the content, design and culture of romance novels and other erotic texts in order to excavate my own queer romance narrative. The body of work includes large-scale drawings of “stand-in boyfriends” stolen from romance novel covers, pieced fabric text works based on the titles of erotic texts, and a couch covered in erotic reading material. Drawing attention to the ubiquity of heterosexualized images and texts by deconstructing them, my work critically questions larger social constructions of normality and deviance, pleasure and …

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Powerful Snp Set Analysis For Case-Control Genome Wide Association Studies, Michael C. Wu, Peter Kraft, Michael P. Epstein, Deanne M. Taylor, Stephen J. Chanock, David J. Hunter, Xihong Lin May 2010

Powerful Snp Set Analysis For Case-Control Genome Wide Association Studies, Michael C. Wu, Peter Kraft, Michael P. Epstein, Deanne M. Taylor, Stephen J. Chanock, David J. Hunter, Xihong Lin

Harvard University Biostatistics Working Paper Series

No abstract provided.

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"It's No Secret": The Experiences Of Eight Lesbian Public School Administrators With District Personnel, Students And Their Parents, Kelly Marie Grigsby May 2010

"It's No Secret": The Experiences Of Eight Lesbian Public School Administrators With District Personnel, Students And Their Parents, Kelly Marie Grigsby

Dissertations

“…These questions are always hard to answer because when you’re living gay, you don’t know which decisions you’re making because you’re gay or because you’re living” (Adrian 596 – 598). The purpose of this phenomenological study was to explore the ways lesbian school administrators in K-12 public schools answer questions about their sexuality from students and their parents and how their feelings, experiences and this partial or potential closet affect their leadership. I completed a series of three in depth interviews with eight European American school administrators that identify as lesbian. I begin by sharing a snapshot of the participants’ …

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Ua35/11 Arête May 2010, Honors College May 2010

Ua35/11 Arête May 2010, Honors College

Arête: Honors College at WKU Newsletter

No abstract provided.

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Methods And Compounds For Inhibition Of Cell Death, Antonis Zervos May 2010

Methods And Compounds For Inhibition Of Cell Death, Antonis Zervos

UCF Patents

This invention is directed to methods and compositions for inhibiting caspase-independent apoptosis. In particular, methods and compositions for inhibiting Omi/HtrA2 activity, as well as method for identifying other inhibitors of Omi/HtrA2. Also disclosed are Omi/HtrA2 specific substrates and methods for identifying other substrates of Omi/HtrA2.

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Comparative Transcriptional Profiling Identifies Takeout As A Gene That Regulates Life Span, Johannes Bauer, Michael Antosh, Chengyi Chang, Christoph Schorl, Santharam Kolli, Nicola Neretti, Stephen L. Helfand May 2010

Comparative Transcriptional Profiling Identifies Takeout As A Gene That Regulates Life Span, Johannes Bauer, Michael Antosh, Chengyi Chang, Christoph Schorl, Santharam Kolli, Nicola Neretti, Stephen L. Helfand

Biosciences Research

A major challenge in translating the positive effects of dietary restriction (DR) for the improvement of human health is the development of therapeutic mimics. One approach to finding DR mimics is based upon identification of the proximal effectors of DR life span extension. Whole genome profiling of DR in Drosophila shows a large number of changes in gene expression, making it difficult to establish which changes are involved in life span determination as opposed to other unrelated physiological changes. We used comparative whole genome expression profiling to discover genes whose change in expression is shared between DR and two molecular …

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Method Of Using Electric Fields To Facilitate The Entry Of Molecules Into Cells In Vivo, Mark J. Jaroszeski, Richard Gilbert, Richard Heller May 2010

Method Of Using Electric Fields To Facilitate The Entry Of Molecules Into Cells In Vivo, Mark J. Jaroszeski, Richard Gilbert, Richard Heller

USF Patents

A method for facilitating a delivery of a molecule into an interior space of a cell includes the steps of introducing a molecule into a target tissue comprising a cell and applying a substantially continuous low-level electric field to the target tissue. The field is applied for a duration sufficient to effect a change in porosity the cell of the target tissue sufficient to facilitate an entry of a desired molecule into an interior of the cell.

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Inhibition Of The Raf/Mek/P-Erk Pathway For Treating Cancer, Said M. Sebti May 2010

Inhibition Of The Raf/Mek/P-Erk Pathway For Treating Cancer, Said M. Sebti

USF Patents

The invention disclosed herein provides for methods of treating cancer using inhibitors of the Raf/Mek/P-Erk 1/2 pathway. These inhibitors include B2AR agonists (such as ARA-211 (pirbuterol) and isoproterenol), adenylyl cyclase activators, cAMP analogs and Epac activators. The invention also provides methods for diagnosing cancer in an individual.

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Control Of Nk Cell Function And Survival By Modulation Of Ship Activity, William G. Kerr May 2010

Control Of Nk Cell Function And Survival By Modulation Of Ship Activity, William G. Kerr

USF Patents

Inhibition of dendritic cell function in solid organ grafts or allogeneic bone marrow transplants prior to or during engraftment by blocking SH2-containing inositol phosphatase (SHIP) expression or function is taught as a method of abrogating immune rejection and thereby increasing the efficacy of engraftment of an allogeneic bone marrow transplant or solid organ allograft or xenograft. Also disclosed is a transgenic mouse having the genotype SHIP−/− which exhibits enhanced survival following mismatched allogeneic marrow grafts.

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A Brain-Specific Cytochrome P450 Responsible For The Majority Of Deltamethrin Resistance In The Qtc279 Strain Of Tribolium Castaneum, Fang Zhu, R. Parthasarathy, Hua Bai, Katharina Woithe, Martin Kaussmann, Ralf Nauen, Douglas A. Harrison, Subba R. Palli May 2010

A Brain-Specific Cytochrome P450 Responsible For The Majority Of Deltamethrin Resistance In The Qtc279 Strain Of Tribolium Castaneum, Fang Zhu, R. Parthasarathy, Hua Bai, Katharina Woithe, Martin Kaussmann, Ralf Nauen, Douglas A. Harrison, Subba R. Palli

Entomology Faculty Publications

Cytochrome P450-mediated detoxification is one of the most important mechanisms involved in insecticide resistance. However, the molecular basis of this mechanism and the physiological functions of P450s associated with insecticide resistance remain largely unknown. Here, we exploited the functional genomics and reverse genetic approaches to identify and characterize a P450 gene responsible for the majority of deltamethrin resistance observed in the QTC279 strain of Tribolium castaneum. We used recently completed whole-genome sequence of T. castaneum to prepare custom microarrays and identified a P450 gene, CYP6BQ9, which showed more than a 200-fold higher expression in the deltamethrin-resistant QTC279 strain when compared …

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Advancing The Future Of Physical Activity Guidelines In Canada: An Independent Expert Panel Interpretation Of The Evidence, Antero Kesäniemi, Chris J. Riddoch, Bruce Reeder, Steven N. Blair, Thorkild I. A. Sørensen May 2010

Advancing The Future Of Physical Activity Guidelines In Canada: An Independent Expert Panel Interpretation Of The Evidence, Antero Kesäniemi, Chris J. Riddoch, Bruce Reeder, Steven N. Blair, Thorkild I. A. Sørensen

Faculty Publications

The Canadian Society for Exercise Physiology, in partnership with the Public Health Agency of Canada, has initiated a review of their physical activity guidelines to promote healthy active living for Canadian children, youth, adults and older adults; previous guidelines were released in 2002, 2002, 1998 and 1999 respectively. Several background papers from this project were published recently and provide foundation evidence upon which to base new guidelines. Furthermore, comprehensive systematic reviews were completed to ensure a rigorous evaluation of evidence informing the revision of physical activity guidelines for asymptomatic populations. The overall guideline development process is being guided and assessed …

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Artificial Selection For Determinate Growth Habit In Soybean, Zhixi Tian, Xiaobo Wang, Rian Lee, Yinghui Li, James E. Specht, Randall L. Nelson, Phillip E. Mcclean, Lijuan Qiu, Jianxin Ma May 2010

Artificial Selection For Determinate Growth Habit In Soybean, Zhixi Tian, Xiaobo Wang, Rian Lee, Yinghui Li, James E. Specht, Randall L. Nelson, Phillip E. Mcclean, Lijuan Qiu, Jianxin Ma

Department of Agronomy and Horticulture: Faculty Publications

Determinacy is an agronomically important trait associated with the domestication in soybean (Glycine max). Most soybean cultivars are classifiable into indeterminate and determinate growth habit, whereas Glycine soja, the wild progenitor of soybean, is indeterminate. Indeterminate (Dt1/Dt1) and determinate (dt1/dt1) genotypes, when mated, produce progeny that segregate in a monogenic pattern. Here, we show evidence that Dt1 is a homolog (designated as GmTfl1) of Arabidopsis terminal flower 1 (TFL1), a regulatory gene encoding a signaling protein of shoot meristems. The transition from indeterminate to determinate phenotypes in soybean is associated …

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The Relationship Between Treatment-Seeking And Characteristics Of Depression Among African Americans, Tamara Scott May 2010

The Relationship Between Treatment-Seeking And Characteristics Of Depression Among African Americans, Tamara Scott

Theses and Dissertations

Objective: Depression is a common psychiatric condition, and despite the availability of effective treatments, this condition is largely under-recognized and undertreated, particularly among African Americans. One reason for this discrepancy may be that depressive symptoms often co-occur with physical health conditions, which can influence both the reporting of depressive symptomology, willingness to seek care, and the type of healthcare provider sought. The purpose of this study was to explore the relationship between treatment-seeking characteristics and diagnostic attributions of depression among community-dwelling African American adults. Methods: Data come from the National Survey of American Life, a nationally representative sample of African …

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Self-Ligating Vs. Conventional Brackets As Perceived By Orthodontists, Chase Prettyman May 2010

Self-Ligating Vs. Conventional Brackets As Perceived By Orthodontists, Chase Prettyman

Theses and Dissertations

Introduction: Within the past decade, significant developments, new designs, and numerous proposed advantages of self-ligating (SL) brackets have caused them to gain great popularity among practicing orthodontists. The purpose of this study was to determine if there are significant clinical differences between SL and conventional brackets on orthodontic treatment as perceived by practicing orthodontists, and more specifically, if the proposed advantages of SL brackets are evident in clinical practice. Methods: A survey was developed to evaluate how SL brackets compare to conventional brackets when perceived by practicing orthodontists (n=430). The initial series of questions focused on individual practitioner characteristics and …

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