Digital Commons Network^™

Vista: September 30, 2010, University Of San Diego

USD Vista (1965-)

No abstract provided.

The Biogeochemistry Of Submerged Coastal Karst Features In West Central Florida, Keith Michael Garman

USF Tampa Graduate Theses and Dissertations

West Central Florida is a complex karst environment with numerous sinkholes, springs, and submerged cave systems. Many of these karst features are anchialine, located within the subterranean estuary where freshwater and saltwater mix. Water quality data and/or fauna data were obtained from twenty-one karst features and their associated cave systems. The anchialine karst environment of the study area has a wide range of habitats with measured salinities ranging from freshwater at <0.2 ppt to sulfidic, hypersaline water at 38.5 ppt and measured pH readings ranging from 6.39 in water impacted by sulfur oxidizing bacteria to 10.3 in an isolated room of a cave. Stygobitic crustaceans were identified in conduits extending beneath the Gulf of Mexico supporting the hypotheses that freshwater crustaceans could survive higher sea levels in freshwater conduits beneath saltwater. The fauna associated with the anchialine cave systems included Sabellidae and Polychaeta worms, hydroids, cnidarians and hydrobiid snails. Jewfish Sink, like other anaerobic marine basins that were submarine springs, has four zones: oxic zone, transition zone, upper anoxic zone and anoxic bottom water. The upper zones have seasonal water quality variations from winter cooling and sinking of surface water and changes in the microbial communities. Activity of sulfate reducing bacteria is carbon limited in the anoxic zones, where sulfate reduction is the major metabolic process, and primary production is phosphate limited in the oxic zones. Organic input from the Gulf of Mexico drives the bacterial anaerobic ecosystem, resulting in a “sulfide pump”, in which sulfide percolates upward removing oxygen from the overlying sediment.

New Mechanism For Notch Signaling To Endothelium At A Distance By Delta-Like 4 Incorporation Into Exosomes, H Sheldon, E Heikamp, H Turley, R Dragovic, Et Al

School of Biomedical Sciences

Notch signaling is an evolutionary conserved pathway that is mediated by cell-cell contact. It is involved in a variety of developmental processes and has an essential role in vascular development and angiogenesis. Delta-like 4 (Dll4) is a Notch ligand that is up-regulated during angiogenesis. It is expressed in endothelial cells and regulates the differentiation between tip cells and stalk cells of neovasculature. Here, we present evidence that Dll4 is incorporated into endothelial exosomes. It can also be incorporated into the exosomes of tumor cells that overexpress Dll4. These exosomes can transfer the Dll4 protein to other endothelial cells and incorporate …

Book Reviews And Notes., Paul Carus

The Open Court

No abstract provided.

Religion In France., Dr. Paul Topinard

The Open Court

No abstract provided.

A New Theory Of The Origin Of Species., J. Arthur Harris

The Open Court

No abstract provided.

Using The R Package Crlmm For Genotyping And Copy Number Estimation, Robert B. Scharpf, Rafael Irizarry, Walter Ritchie, Benilton Carvalho, Ingo Ruczinski

Johns Hopkins University, Dept. of Biostatistics Working Papers

Genotyping platforms such as Affymetrix can be used to assess genotype-phenotype as well as copy number-phenotype associations at millions of markers. While genotyping algorithms are largely concordant when assessed on HapMap samples, tools to assess copy number changes are more variable and often discordant. One explanation for the discordance is that copy number estimates are susceptible to systematic differences between groups of samples that were processed at different times or by different labs. Analysis algorithms that do not adjust for batch effects are prone to spurious measures of association. The R package crlmm implements a multilevel model that adjusts for …

Estimating Temporal Associations In Electrocorticographic (Ecog) Time Series With First Order Pruning, Haley Hedlin, Dana Boatman, Brian Caffo

Johns Hopkins University, Dept. of Biostatistics Working Papers

Granger causality (GC) is a statistical technique used to estimate temporal associations in multivariate time series. Many applications and extensions of GC have been proposed since its formulation by Granger in 1969. Here we control for potentially mediating or confounding associations between time series in the context of event-related electrocorticographic (ECoG) time series. A pruning approach to remove spurious connections and simultaneously reduce the required number of estimations to fit the effective connectivity graph is proposed. Additionally, we consider the potential of adjusted GC applied to independent components as a method to explore temporal relationships between underlying source signals. Both …

09-29-2010 Swosu Receives Research Mentor Grant, Southwestern Oklahoma State University

THE BARK ARCHIVE 2010

Southwestern Oklahoma State University and three faculty members are the latest recipients of the INBRE research mentor grants as a collaborating institution with the University of Oklahoma Health Sciences Center.

Nor'easter News Volume 4 Issue 1, Nor'easter News Staff

Nor'easter News

The twenty-eighth issue of the University of New England's student-run newspaper, Nor'easter News.

Spartan Daily September 29, 2010, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily (School of Journalism and Mass Communications)

Volume 135, Issue 17

"The Crescent" Student Newspaper, September 29, 2010, George Fox University Archives

"The Crescent" Student Newspaper

Student newspaper of George Fox University.

Volume 48, Number 6: September 29, 2010, University Of North Dakota

University Letter Archive

No abstract provided.

The Anchor, Volume 124.04: September 29, 2010, Hope College

The Anchor: 2010

The Anchor began in 1887 and was first issued weekly in 1914. Covering national and campus news alike, Hope College’s student-run newspaper has grown over the years to encompass over two-dozen editors, reporters, and staff. For much of The Anchor's history, the latest issue was distributed across campus each Wednesday throughout the academic school year (with few exceptions). In recent years The Anchor moved to monthly print issues and a more frequently updated website. The Anchor is now published in print twice per academic semester. Occasionally, the volume and/or issue numbering is irregular.

Stony Brook Press, V. 32, N. 02, Stony Brook University. Stony Brook Press.

Stony Brook Press

v. 32, n. 02, v.:ill. ; 38 cm (original analog pub.)

Rotunda - Vol 89, No 5 - Sep 29, 2010, Longwood University

Rotunda

No abstract provided.

The Winonan, Winona State University

The Winonan - 2010s

No abstract provided.

Uab College Of Arts And Sciences Announces Scholarships, Shannon Thomason

Browse All News

No abstract provided.

Uab College Of Arts And Sciences Announces Scholarships, Staff

Browse All News

No abstract provided.

Daily Eastern News: September 29, 2010, Eastern Illinois University

September

No abstract provided.

The Spinnaker [Vol. 33 No. 40], University Of North Florida

Spinnaker

Student newspaper for the UNF community.

The Daily Egyptian, September 29, 2010, Daily Egyptian Staff

September 2010

No abstract provided.

The Lumberjack, September 29, 2010

Cal Poly Humboldt's Student Newspaper

The student newspaper of Humboldt State University.

Whalesong 2010-09-29 (V.29 No.2), Randi Spray, Mallory Millay, Tyler Preston, Andria Budbill, Rich Moniak, Pat Race

Whalesong

No abstract provided.

Identification Of An Archaeal Presenilin-Like Intramembrane Protease, Celia Torres-Arancivia, Carolyn M. Ross, Jose Chavez, Zahra Assur, Georgia Dolios, Filippo Mancia, Iban Ubarretxena-Belandia

Publications and Research

Background: The GXGD-type diaspartyl intramembrane protease, presenilin, constitutes the catalytic core of the c-secretase multi-protein complex responsible for activating critical signaling cascades during development and for the production of b-amyloid peptides (Ab) implicated in Alzheimer’s disease. The only other known GXGD-type diaspartyl intramembrane proteases are the eukaryotic signal peptide peptidases (SPPs). The presence of presenilin-like enzymes outside eukaryots has not been demonstrated. Here we report the existence of presenilin-like GXGD-type diaspartyl intramembrane proteases in archaea.

Methodology and Principal Findings: We have employed in vitro activity assays to show that MCMJR1, a polytopic membrane protein from the archaeon Methanoculleus marisnigri JR1, …

The Colby Echo (2010-09-29), Colby College

The Colby Echo

Published by the students of Colby College since 1877, The Colby Echo is the weekly, editorially independent student-run newspaper of Colby College in Waterville, Maine. Published monthly, 1877-1886; semi-monthly, 1886-1897; and weekly, during the academic year, 1898-present.

September 29, 2010, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

The Antelope, University Of Nebraska At Kearney

The Antelope

No abstract provided.

Spartan Daily September 28, 2010, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily (School of Journalism and Mass Communications)

Volume 135, Issue 16

Ethical Considerations In Access To Experimental Drugs For Treatment Use, Sonja Rakowski

Yale Medicine Thesis Digital Library

Do dying patients have a moral claim to access experimental drugs when all else has failed? This question has been the focus of an active and evolving debate concerning the rights of terminally ill patients, the nature of the drug development process, and the scope of federal regulation, with supporters arguing that seriously ill patients should be able to decide for themselves whether and when to attempt experimental therapies and opponents arguing that the resulting state of affairs would be disastrous for patient safety and for the integrity of the drug development process. This thesis concerns the ethical considerations surrounding …