Digital Commons Network^™

Particle Swarm Optimization And Gravitational Wave Data Analysis: Performance On A Binary Inspiral Testbed, Yan Wang, Soumya Mohanty

Physics & Astronomy Faculty Publications

The detection and estimation of gravitational wave signals belonging to a parameterized family of waveforms requires, in general, the numerical maximization of a data-dependent function of the signal parameters. Because of noise in the data, the function to be maximized is often highly multimodal with numerous local maxima. Searching for the global maximum then becomes computationally expensive, which in turn can limit the scientific scope of the search. Stochastic optimization is one possible approach to reducing computational costs in such applications. We report results from a first investigation of the particle swarm optimization method in this context. The method is …

Toward A Grounded Theory On The Management Of Orphanages In South Africa And Zimbabwe, Anna Siyavora

Walden Dissertations and Doctoral Studies

The number of orphaned children in many parts of Africa is increasing as their parents die from human immunodeficiency virus (HIV) or acquired immune deficiency syndrome (AIDS). The research problem addressed in this qualitative study was lack of understanding by others about how the managers of orphanages in 2 African countries -- South Africa and Zimbabwe - were responding to the emotional and social needs of these orphans. The purpose of this study was to develop an orphanage management theory or model that could replicate the African kinship environment in the orphanages under study. Nurturing leadership theory provided the conceptual …

Differential Gene Expression Profile Of Retinoblastoma Compared To Normal Retina., Arupa Ganguly, Carol L Shields

Wills Eye Hospital Papers

PURPOSE: The retinoblastoma gene (RB1) is a tumor suppressor gene that was first discovered in a rare ocular pediatric tumor called retinoblastoma (RB). The RB1 gene is essential for normal progression through the cell cycle and exerts part of its function through the family of transcription factors (E2F) and many other intermediaries. In the absence of normal RB1, genomic instability and chromosomal aberrations accumulate, leading to tumor initiation, progression, and ultimately metastasis. The purpose of this report was to identify the molecular pathways that are deregulated in retinoblastoma.

METHODS: We compared gene expression signatures of matched normal retinal tissue and …

Autoimmunity In Transfusion Babesiosis: A Spectrum Of Clinical Presentations., Jay H Herman, Saleh Ayache, Danuta Olkowska

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Transfusion-acquired babesiosis can be an asymptomatic or self-limited febrile hemolytic illness in a healthy host. A persistent, relapsing, and/or fulminant course with the development of life-threatening complications may be seen in immunocompromised or splenectomized patients. As in malaria, erythrocyte parasitemia is often associated with nonimmune hemolysis, and can be treated with erythrocytapheresis. Just as warm autoantibodies have been reported in malaria infection, the development of autoantibody-mediated immune hemolysis has been reported in babesiosis. We treated a previously healthy male with multiple injuries from a motor vehicle accident necessitating massive transfusion. Late in the hospitalization, his blood smear revealed Babesia microti, …

Sustained Expression Of Tdp-43 And Fus In Motor Neurons In Rodent's Lifetime., Cao Huang, Pedro Yuxing Xia, Hongxia Zhou

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

TAR DNA-binding protein (TDP-43) and fused in sarcoma (FUS) are two highly conserved ribonucleoproteins. Pathogenic mutations of the TDP-43 or the FUS gene are all linked to amyotrophic lateral sclerosis (ALS) that is characterized by progressive degeneration of motor neurons. To better understand the correlation of ALS disease genes with the selectivity of chronic motor neuron degeneration, we examined the longitudinal expression of the TDP-43 and the FUS genes in C57BL6 mice and in Sprague-Dawley rats. TDP-43 and FUS were robustly and ubiquitously expressed in the postnatal mice and rats, but were markedly decreased in the adult rodents. In adulthood, …

The Role Of Socioeconomic Factors In Racial And Ethnic Disparities Among Child And Adult Tuberculosis Cases, Spatial And Non-Spatial Analysis: Alabama 1993-2007, Sharada Adolph

All ETDs from UAB

This study aimed to evaluate the role of individual and community/population level socioeconomic factors on racial/ethnic disparities among children and adults with TB, and used area-based socioeconomic measures (ABSMs) for the identification of high-risk geographic areas for populations-at-risk. Joinpoint, multivariable and Poisson regression, and spatial methods were used to determine the trends and risks of disease in a low TB incidence state. General disease trends declined significantly by factors of -0.044838 from 1993-1998, and -0.061821 from 2001-2007; but, were disparate and increased for the foreign-born, African Americans (AA) and Latinos, and in long-term care settings. The average annual percentage change …

The Role Of Socs Proteins In Hiv Immune Evasion, Lisa Nowoslawski Akhtar

All ETDs from UAB

Upon human immunodeficiency virus (HIV) infection the host mounts a robust and multifaceted immune response. To achieve successful replication, HIV must possess a powerful arsenal of immune evasion weapons. While a complex strategy for HIV immune evasion has been described in the periphery, little is known about the mechanism allowing HIV to overcome the simple interferon (IFN)-ß-mediated innate immune defenses of the central nervous system (CNS). In light of the devastating cognitive dysfunction that is caused by HIV replication within the CNS, a better understanding of this mechanism is critical. Recent studies have shown that viral pathogens can induce the …

Mechanisms By Which Tra-8 Anti-Dr5 Antibody And Chemotherapy Enhance Cytotoxicity In Breast Cancer, Hope M. Amm

All ETDs from UAB

Breast cancer is the second leading cause of cancer-related death in American women and metastatic breast cancer has a 5-year survival rate of only 26%. Current targeted treatments for this disease include anti-estrogen strategies for estrogen receptor positive tumors (~60%) and anti-Her2/Neu strategies for tumors overexpressing this receptor (20-25%). A percentage of breast cancer patients, however, are resistant to these therapies and are left without any effective treatment options. One of the agents currently being investigated to improve breast cancer survival is TRA-8, an agonistic monoclonal antibody to death receptor 5 (DR5), which induces apoptosis in various types of cancer …

The Effectiveness Of Advanced Oxidation Techniques In Degrading Steroids In Wastewater, Bryan Stuart Arwood

All ETDs from UAB

No abstract provided.

Effect Of Dietary Protein An D Carbohydrate Levels On Weight Gain And Organ Production In The Sea Urchin Lytechinus Variegatus, Laura E Wright Heflin

All ETDs from UAB

No abstract provided.

The Combined Influence Of The Local Environment Andregional Enrichment On Bird Species Richness, Ethan P. White, A. H. Hurlbert

Biology Faculty Publications

It is generally accepted that local species richness at a site reflects the combined influence of local and regional processes. However, most empirical studies evaluate the influence of either local environmental variables or regional enrichment but not both simultaneously. Here we demonstrate the importance of combining these processes to understand continental scale richness patterns in breeding birds. We show that neither regional enrichment nor the local environment in isolation is sufficient to characterize observed patterns of species richness. Combining both sets of variables into a single model results in improved model fit and the removal of residual spatial autocorrelation. At …

Loss Of Foundation Species Increases Population Growth Of Exotic Forbs In Sagebrush Steppe, J S. Prevey, M J. Germino, Nancy J. Huntly

Biology Faculty Publications

The invasion and spread of exotic plants following land disturbance threatens semiarid ecosystems. In sagebrush steppe, soil water is scarce and is partitioned between deeprooted perennial shrubs and shallower-rooted native forbs and grasses. Disturbances commonly remove shrubs, leaving grass-dominated communities, and may allow for the exploitation of water resources by the many species of invasive, tap-rooted forbs that are increasingly successful in this habitat. We hypothesized that exotic forb populations would benefit from increased soil water made available by removal of sagebrush, a foundation species capable of deep-rooting, in semiarid shrub-steppe ecosystems. To test this hypothesis, we used periodic matrix …

Seasonal Patterns Of Arthropod Diversity And Abundance On Big Sagebrush, Artemisia Trientata, M P. Stanford, Nancy J. Huntly

Biology Faculty Publications

The sagebrush biotype is the largest in the western United States. This vast sagebrush community is thought to harbor equally vast and diverse arthropod communities, but these remain little explored. Our objective was to examine the diversity, abundance, and seasonal phenology of arthropod taxa found on the dominant shrub of the sagebrush ecosystem, big sagebrush (Artemisia tridentata). We wanted to improve understanding of this little-studied arthropod assemblage that may play significant roles in the dynamics of sagebrush populations and the sagebrush ecosystem. We sampled free-living and gall-forming arthropods from a stratified random sample of sagebrush plants at the Barton Road …

Volunteering With Friends Groups Is Rewarding Experience, John J. Roberts

Georgia Library Quarterly

The author discusses the role of libraries and books throughout his youth and professional career and his belief in their value to the community. Due to reduced state funding for public libraries, his family reportedly joined The Friends of The Libraries group to volunteer for fundraising efforts. It is stated that they sorted books and handled book sales and donations and have provided 80 percent of new books to those who need them.

Open Source Analysis Of Biomedical Figures, David Shao

Master's Projects

With a selection of biomedical literature available for open access, a natural pairing seems to be the use of open source software to automatically analyze content, in particular, the content of gures. Considering the large number of possible tools and approaches, we choose to focus on the recognition of printed characters. As the problem of optical character recognition (OCR) under rea- sonable conditions is considered to be solved, and as open source software is fully capable of isolating the location of characters and identifying most of them accurately, we instead use OCR as an application area for the relatively recent …

Catholic Feminism And Asian Religious Traditions: Rethinking Christ’S Offices Of Priest, Prophet, And King, Tracy Tiemeier

Theological Studies Faculty Works

No abstract provided.

Engendering The ‘Mysticism’ Of The Alvars, Tracy Tiemeier

Theological Studies Faculty Works

This essay explores the relationship between gender, power, and mysticism through an examination of the Tamil Vaiṣṇava Ālvārs and how two scholars, Friedhelm Hardy and S.M. Srinivasa Chari, interrelate Ālvār mysticism, female voice, and the one female Ālvār, Āṇṭāḷ. Although both Hardy and Chari define Ālvār mysticism through female voice and uphold Āṇṭāḷ as mystic par excellence, they miss important nuances of Āṇṭāḷ's poetry that radicalise female voice and frustrate gendered expectations. Āṇṭāḷ's mysticism proves to be socially and theologically subversive, laying claim to authority even over the divine.

Reading Out Of Doors: How Nature Becomes Text And Vice-Versa, Richmond Minor Eustis

LSU Doctoral Dissertations

The tensions between city and country, the artificial and the natural, the real and the fake are at the heart of attempts to render nature in writing. In many such texts, nature—especially wilderness—is the realm of the real, authentic, and pure, while the city is the realm of the artificial and corrupt. This placement of value in nature, members of the critical theory camp tend to counter, is misguided. Any effort to render nature in text is by its “nature” artificial—far more about human values embedded in language itself than about some extra-textual world. With an approach derived from theorists …

Other Tomorrows: Postcoloniality, Science Fiction And India, Suparno Banerjee

LSU Doctoral Dissertations

In this dissertation I argue that science fiction as a genre intervenes in the history-oriented discourse of postcolonial Anglophone Indian literature and refocuses attention on the nation’s future—its position in global politics, its shifting religious and social values, its rapid industrialization, the clash between orthodoxy and modernity, and ultimately the dream of a multicultural nation. Anglophone Indian science fiction also indicates India’s movement away from a nation trying to negotiate the stigma of colonialism to a nation emerging as a new world power. Thus, this genre reconstructs the Indian identity not only in the domestic sphere, but also in a …

Modeling And Simulation For Shape Memory Polymer Based Self-Healing Syntactic Foam, Wei Xu

LSU Doctoral Dissertations

Syntactic foams, renowned for their low density and high mechanical properties, are enjoying continuing growth in various civilian and military sectors. However, like laminated composites, foam cored structures are vulnerable to impact damages and suffering from inabilities in repairing macro-scale cracks. A self-healing mechanism for structural damage is genuinely desired. A recent development in self-healing structural damage is a two-step close then heal (CTH) scheme proposed by Li and Nettles [1] and elucidated by Li and Uppu [2], by mimicking the self-healing process of human skin. This concept has been further demonstrated in Nji and Li’s work [3] that a …

Oxidation Of Reduced Sulfur Compounds: A Triple-Oxygen-Isotope Perspective, Issaku E. Kohl

LSU Doctoral Dissertations

The Earth’s geochemical evolution is recorded in the rocks that compose its lithosphere. Specifically, sulfate minerals have been identified as being repositories of information concerning the past hydrosphere, atmosphere and biosphere. This is due to the non-labile nature of SO42- and its ability to store a record of the oxidative reactions and oxygen sources involved in its formation. Microbial dissimilatory sulfate reduction (MDSR) and sulfide oxidation cause oxygen from H2O and O2 to be trapped to varying degrees in ambient, dissolved SO42-. In order to better interpret the H2O and O2 signals in SO42-, we must deepen our understanding of …

Common Data Set, 2009-2010, Planning, Research, And Policy Analysis

Common Data Set (2001-present)

Common Data Set 2009-2010 for Illinois State University

The Development Of A Model Program For The Effective Management Of Biomedical Waste In The Caribbean. A Review Of Barriers Within Public Hospitals In The Caribbean., Andrea Spence

Theses

When biomedical waste is improperly managed it poses a health hazard and risk to healthcare workers, sanitation workers and the general public in contracting infectious/dangerous diseases. Biomedical waste is also generated from individuals in their homes from the use of syringes or diagnostic lancets that are not properly managed. Biomedical waste is considered special waste and has a health and environmental hazard that can result in infections and diseases such as HIV/AIDs. Discarded sharps pose a health risk to the public particularly solid waste workers who may suffer a needle stick injury if they are not properly packaged for disposal. …

Choosing One: Resolving The Epidemic Of Multiples In Assisted Reproduction, Theresa Glennon

Villanova Law Review (1956 - )

No abstract provided.

Finding A Footing: A Theological Perspective On Law And The Work Of Joseph Vining, John L. Mccausland

Villanova Law Review (1956 - )

No abstract provided.

Symposium Introduction, Various Editors

Villanova Law Review (1956 - )

No abstract provided.

Structure And Content Semantic Similarity Detection Of Extensible Markup Language Documents Using Keys, Waraporn Viyanon

Doctoral Dissertations

"XML (eXtensible Mark-up Language) has become the fundamental standard for efficient data management and exchange. Due to the widespread use of XML for describing and exchanging data on the web, XML-based comparison is central issues in database management and information retrieval. In fact, although many heterogeneous XML sources have similar content, they may be described using different tag names and structures. This work proposes a series of algorithms for detection of structural and content changes among XML data. The first is an algorithm called XDoI (XML Data Integration Based on Content and Structure Similarity Using Keys) that clusters XML documents …

Borate Based Bioactive Glass Scaffolds For Hard And Soft Tissue Engineering, Steven B. Jung

Doctoral Dissertations

"The main objectives of this dissertation were to evaluate bioactive borate glass scaffolds for hard and soft tissue applications and determine the potential toxicity of the borate glasses on the adjacent and systemic tissues. Porous randomly oriented fiber scaffolds composed of bioactive borate glass were implanted in subcutaneous soft tissue sites and in calvaria defects of laboratory rats and no signs of toxicity (necrotic tissue, increase in macrophages or other immune cells) were detected in any of the adjacent tissues (hard or soft). Systemic organs (kidney and liver) of laboratory rats implanted with bioactive borate scaffolds were analyzed for possible …

The Stereochemistry Of Selected Supramolecular Complexes Of Cucurbiturils And The Effect Of Homogeneous Equilibria And Electron Transfer Of The Guest, Arumugam Thangavel

Doctoral Dissertations

"From a practical perspective, host-guest complexes are vehicles for understanding and using supramolecular interactions for purposeful function in sensors, molecular machines and switches, while from a fundamental perspective they may lead to novel supramolecular protection schemes in basic organic reactions. This dissertation examines the interactions of cucurbiturils as barrel-shaped hosts, exhibiting a hydrophobic cavity, with substituted benzoylpyrydinium, phenypyrylium, and diazaanthraquinonediium cations as guests. In water, N-methyl-4-(p-substituted benzoyl)pyridinium cations exist in equilibrium with their hydrated forms (gem-diols), whose concentrations depend on the para substituent. In the presence of cucurbit7uril (CB[7]), the benzoyl group shows a preference for the CB[7] cavity, and …

Computational Intelligence Methods In Wireless Sensor Networks, Raghavendra V. Kulkarni

Doctoral Dissertations

"Wireless sensor networks (WSNs) are networks of autonomous nodes that sense, compute and communicate in order to monitor an environment collectively. Ad hoc deployment, dynamic environment and resource constraints in nodes need to be considered while addressing WSN challenges such as deployment, localization, routing and scheduling. Adaptive mechanisms that exhibit intelligent behavior in complex and dynamic environments are desirable to address these challenges. The potential of computational intelligence ( CI) based approaches for addressing WSN challenges is investigated in this study. Contributions of this dissertation are in the following three areas: critical literature analysis, new architectures and approaches, and new …