Digital Commons Network^™

Successful Treatment Of Severe Stenosis Of The Posterior Cerebral Artery With Percutaneous Transluminal Angioplasty And Stenting, Chun-Xia Luo, Lu-Xiang Chi, Wen-Hui Fan, Kang-Ning Chen

Neurosciences

Cerebral arterial stenosis is a major cause of stroke and of insufficient blood supply to the vertebral basilar system. Percutaneous transluminal cerebral angioplasty and stenting (PTCAS) have been used to preliminarily treat vertebrobasilar stenosis. However, the feasibility to treat the posterior cerebral arterial stenosis by PTCAS has not been fully established. We report a case of a 64-year-old man with a severe stenosis of the posterior cerebral artery that was treated successfully using a PTCAS procedure.

Headbanging By Pigeons: A Systematic Replication And Extension Of An Animal Model Of Psychopathology, Allison H. Hahn

All NMU Master's Theses

No abstract provided.

The Occurrence Of The Subgenus Microlaccobius Gentili In Turkey (Coleoptera: Hydrophilidae, Laccobius), With Taxonomic Notes, Mustafa Cemal Darilmaz, Suat Kiyak

Turkish Journal of Zoology

Distributional data and the chorotype of all known taxa of Turkish species of the subgenus Microlaccobius Gentili, 1974 are summarized. The taxonomic position of Laccobius gracilis persicus Gentili, 1974 is discussed and L. persicus is elevated to the level of valid species and new record for the Turkish fauna. A short identification key of Turkish species of the subgenus is also given.

Histology Of The Androgenic Gland In Eriphia Verrucosa (Forskål, 1775) (Decapoda, Brachyura), Meli̇ke Erkan, Yasemi̇n Tunali, Serap Eki̇nci̇, Si̇mge Kara

Turkish Journal of Zoology

This study investigated the histology of the androgenic gland in Eriphia verrucosa (Forskål, 1775). The results obtained with light microscopy show that the androgenic gland in this species consists of 2 cell types. Type 1 cells are small and do not contain a secretory product. Type 2 cells are considerably larger and may produce a proteinaceous secretion. This study identified the location and structure of the androgenic gland in Eriphia verrucosa, which is an economically important brachyuran crab, and revealed the chemical nature of the secretions produced by its cells.

Age, Growth, Length-Weight Relationship And Reproduction Of The Striped Seabream (Lithognathus Mormyrus L., 1758) (Sparidae) In The Beymelek Lagoon (Antalya, Turkey), Yilmaz Emre, İsmet Balik, Çeti̇n Sümer, D. Aytuğ Oskay, H. Özgür Yeşi̇lçi̇men

Turkish Journal of Zoology

Age, growth, length-weight relationship and reproduction were investigated for striped seabream (Lithognathus mormyrus L., 1758) collected from Beymelek Lagoon (Antalya, Turkey) between February 2006 and January 2007. The ages of striped seabream ranged from 0 to 3 years for males and from 0 to 4 years for females. Their total lengths and weights ranged between 14.4 and 26.4 cm and 42 and 297 g for males and 14.3 and 27.4 cm and 40 and 329 g for females, respectively. The growth parameters of the von Bertalanffy equation were: L_{\infinity} = 28.3 cm, K = 0.456 year^{-1} and t_0 = -1.859 …

Length-Weight Relationships Of Marine Fishes Off Yumurtalık Coast (İskenderun Bay), Turkey, Gökhan Gökçe, Mustafa Çeki̇ç, Hali̇t Fi̇li̇z

Turkish Journal of Zoology

In this study, length and weight data are presented for 33 fish species inhabiting littoral habitats off the Yumurtalık coast. Samples were collected with combined gill and trammel nets. Parameters of the length-weight relationships were estimated for 14 species. The b values ranged between 2.35 and 3.53. For remained 19 species, the parameter a was estimated by setting b = 3.0.

Longwood University Catalog 2010-2011, Longwood University

Undergraduate Catalogs

No abstract provided.

The Relationship Between Mosquito Abundance And Rice Field Density In The Republic Of Korea, Erin E. Richards, Penny Masuoka, David Brett-Major, Matthew Smith, Terry A. Klein, Heung Chul Kim, Assaf Anyamba, John Grieco

Journal Articles: Epidemiology

BACKGROUND: Japanese encephalitis virus (JEV), the causative agent of Japanese encephalitis (JE), is endemic to the Republic of Korea (ROK) where unvaccinated United States (U.S.) military Service members, civilians and family members are stationed. The primary vector of the JEV in the ROK is Culex tritaeniorhynchus. The ecological relationship between Culex spp. and rice fields has been studied extensively; rice fields have been shown to increase the prevalence of Cx. tritaeniorhynchus. This research was conducted to determine if the quantification of rice field land cover surrounding U.S. military installations in the ROK should be used as a parameter in a …

A Model For Understanding Epilepsy In Peromyscus, Kevin Ryan, Gabor Szalai

Journal of the South Carolina Academy of Science

No abstract provided.

The Effects Of The Sumter Wastewater Treatment Plant On The Survival And Reproduction Of Ceriodaphnia Dubia In Chronic Toxicity Tests, Erin Worley, Pearl R. Fernandes, S. Michele Harmon, Jeff Steinmetz

Journal of the South Carolina Academy of Science

No abstract provided.

Do Snakes Use Olfactory Receptors In The Nose To Detect Odors?: A Prediction Based On The Percentage Of Nonfunctional Olfactory Receptor Genes Amplified In Four Species Of Snakes, Taylor Byerly, Amanda Robinson, Michelle Vieyra

Journal of the South Carolina Academy of Science

No abstract provided.

Associative Learning In Larval Dosophila Melanogaster: The Role Of Heredity In Learning Speed And Persistence Of Leaning Into Adulthood, Jasmin Hicklen, Domonique Jones, Michelle Vieyra

Journal of the South Carolina Academy of Science

No abstract provided.

No.68 An Order Establishing The Tennessee Stem Innovation Network, Phil Bredesen

Executive Orders

No abstract provided.

Studies Toward The Total Synthesis Of (±)-Α-Yohimbine By Double Annulation, Raghu Ram Chamala

University of Kentucky Doctoral Dissertations

The indole alkaloids, a class of natural products, have received much synthetic attention for years due to their diverse structures and interesting biological properties. We are particularly interested in synthesizing some of the yohimbine alkaloids extracted from the bark of a tall evergreen African tree (Corynanthe yohimbe, commonly known as fringe tree). Yohimbine and its stereoisomers have been tempting targets for synthetic organic chemists for more than fifty years. These compounds feature a pentacyclic ring system with two heteroatoms and five stereogenic centers.

Broadly, the fifteen different synthetic approaches that led to the successful completion of yohimbine alkaloids …

The Role Of The Ca2+-Dependent Protein Kinase, Camk-Ii, In Heart And Kidney Development In The Zebrafish, Danio Rerio, Sarah Rothschild

Theses and Dissertations

Ca2+/calmodulin-dependent protein kinase type II (CaMK-II) is a multifunctional serine/threonine kinase that is ubiquitously expressed throughout the lifespan of metazoans. Mammals encode four genes (α, β, γ, δ) that generate over forty splice-variants. CaMK-II is important in a myriad of functions, including ion channel regulation, cell-cycle progression, and long term potentiation. In adults, alterations in activation of CaMK-II induce cardiac arrhythmias and heart failure. Developmental roles for CaMK-II are not as well understood since mouse knockouts are embryonic lethal. Therefore the identification of other vertebrate CaMK-II genes will add to our understanding of development. Zebrafish encode seven catalytically active CaMK-II …

Biochemical Characterization Of Suppressor Of Ikk-Ε And Nak-Associated Protein 1, Jonathan Forbes

Theses and Dissertations

Innate immunity provides the first line of defense against invading pathogen by recognizing and mounting a response to the pathogenic challenge. Among the cellular mechanisms of the innate immune response, Toll-like receptor 3 (TLR3) recognizes viral dsRNA and signals subsequent production of type-I interferon. The TLR3:interferon signaling cascades contains a kinase complex composed of two kinases and a scaffold protein, NAK-associated protein 1 (NAP1). The role of NAP1 in modulating kinase activation or regulation is unknown. A key inhibitory protein identified in the TLR3:interferon pathway, silencer of inhibitor of κBα kinase ε (SIKE), blocks the activity of this kinase complex …

Role Of Oxidative Reactive Species And Antioxidants In Metabolism And Transport Of Therapeutic Drugs, Svetlana Verenich

Theses and Dissertations

Oxidative stress (OS) is a frequent complication of various disease conditions such as Alzheimer’s and Parkinson’s disease, atherosclerosis, preeclampsia, rheumatoid arthritis, diabetes including gestational diabetes, etc. OS is defined as an imbalance between the production of reactive species and the ability of an organism to detoxify the reactive intermediates and repair the damage. As a result of OS, the excess of reactive species such as oxygen superoxide (O2-), hydroxyl radical (OH), peroxynitrite (ONOO−), 4-hydroxynonenal (4HNE), etc., have a tendency to react with nearby proteins/nucleic acids/lipids changing their functionality or inactivating them completely. The organism has many ways to protect itself …

P53 Mediated Cell Motility In H1299 Lung Cancer Cells, Mi-Yon Choi

Theses and Dissertations

Studies have shown that gain-of- function mutant p53, AKT, and NFκB promote invasion and metastasis in tumor cells. Signals transduced by AKT and p53 are integrated via negative feedback between the two pathways. Tumor derived p53 was also indicated to induce NFκB gene expression. Due to the close relationship between p53/AKT and p53/NFκB, we hypothesized that AKT and NFκB can enhance motility in cells expressing mutant p53. Effects on cell motility were determined by scratch assays. CXCL5- chemokine is also known to induce cell motility. We hypothesized that enhanced cell motility by AKT and NFκB is mediated, in part, by …

Mirror Neurons, The New Neuroscience, And The Law: Some Preliminary Observations, 39 Sw. L. Rev. 499 (2010), Timothy P. O'Neill

UIC Law Open Access Faculty Scholarship

No abstract provided.

Autotaxin: A Regulator Of Oligodendrocyte Differentiation, Larra Yuelling

Theses and Dissertations

In order for oligodendrocyte progenitor cells (OPCs) to differentiate into fully mature, myelinating oligodendrocytes, they must be specified at the correct times and undergo coordinated changes in both gene expression and morphology. As oligodendrocytes differentiate, they transition from a bipolar morphology into a morphology characterized by a complex network of multiple processes, which will eventually generate membranous structures necessary for myelination of axonal segments. As changes are observed in cellular morphology, oligodendrocytes also undergo changes in their gene expression profile and express genes necessary for both early and later stages of development such as olig1 and myelin basic protein (mbp), …

Health Promotion And Health Education: Nursing Students’ Perspectives, Kathleen Ann Halcomb

University of Kentucky Doctoral Dissertations

The purpose of this study was to determine student nurses’ perceptions of (1) the role of the nurse in health promotion, and (2) how the concept of health promotion is presented in nursing curricula. Research questions for this study included the following: 1) Can nursing students explain the difference between health education and health promotion? 2) What have nursing students been exposed to within their curriculum regarding health promotion? 3) What health promoting behaviors are nursing faculty role modeling as perceived by nursing students? 4) What is the role of the nurse in implementing health promotion as perceived by nursing …

Polychlorinated Biphenyl-Induced Endothelial Cell Dysfunction And Its Modulation By Dietary Lipids, Zuzana Majkova

University of Kentucky Doctoral Dissertations

Cardiovascular diseases are the number one cause of death in Western societies. Endothelial dysfunction is an early event in the pathology of atherosclerosis, which is an underlying cause in the majority of cardiovascular events. Exposure to persistent environmental pollutants, such as polychlorinated biphenyls (PCBs), is a risk factor for the development of atherosclerosis.

First, we tested a hypothesis that coplanar PCBs, dioxin-like chemicals with affinity for aryl hydrocarbon receptor (AhR), can stimulate up-regulation of monocyte chemoattractant protein-1 (MCP-1), an endothelium-derived chemokine that attracts monocytes into sub-endothelial space in early stages of atherosclerosis. Coplanar PCBs 77 and 126 increased expression of …

15N Solid-State Nmr Detection Of Flavin Perturbation By H-Bonding In Models And Enzyme Active Sites, Dongtao Cui

University of Kentucky Doctoral Dissertations

Massey and Hemmerich proposed that the different reactivities displayed by different flavoenzymes could be achieved as a result of dominance of different flavin ring resonance structures in different binding sites. Thus, the FMN cofactor would engage in different reactions when it had different electronic structures. To test this proposal and understand how different protein sites could produce different flavin electronic structures, we are developing solid-state NMR as a means of characterizing the electronic state of the flavin ring, via the ¹⁵N chemical shift tensors of the ring N atoms. These provide information on the frontier orbitals. We propose that …

Repressive Bodies, Transgressive Bodies : Dracula And The Feminine, Sharon Kostopoulos

Theses : Honours

Dracula has long been associated with the repressive qualities of Victorian society and the oppression of the emerging New Woman. However, taking into account that the novel is part of the gothic genre, a genre which endeavours to infringe the social boundaries in any given era, this thesis will demonstrate an equally visible and potent transgressive feminine element playing out in Dracula. Using Michel Foucault's idea of discourse to show how subjects are generated, the novel can be seen as facilitating both productive and repressive ideas of femininity. Power, as it operates through discourse, tends to produce its own resistance, …

The Experience Of Retirement For Individuals With An Intellectual Disability, Megan Flowers

Theses : Honours

Retirement is a significant life transition that affects all workers; it is therefore important that individuals in the workforce are aware of the issues that can occur during the retirement years. The retirement experience has been researched in depth, however studies into the experience of retirement for individuals with an intellectual disability is severely lacking. Robert Atchley researched the factors that facilitate successful retirement adjustment for individuals in the normative population; this narrative review discusses these factors in relation to the barriers that individuals with an intellectual disability face in achieving a smooth retirement adjustment. The results found that: individuals …

Our Grandparents, Our Parents, Our Future Selves: Optimizing Function In Old Age., Thomas Michael Gill

Center for Policy Research

Most of my research at Yale University School of Medicine over the past several years has focused on identifying older adults at risk of functional decline and disability, identifying events that may precipitate the transition from functional independence to disability, and developing strategies to postpone or reduce frailty and disability. As a result of the Precipitating Events Project (PEP) and other research conducted by the Yale Center on Aging/Pepper Center, we now realize that age is only a proxy for other factors that lead to disability, and that some of these factors can be modified to reduce the risk of …

Contents And Abstracts

Basic Communication Course Annual

No abstract provided.

Basic Communication Course Annual Vol. 22

Basic Communication Course Annual

Full issue (241 pages, 8.6 MB)

[Introduction To] Mother Tongues And Nations: The Invention Of The Native Speaker, Thomas Paul Bonfiglio

Bookshelf

This monograph examines the ideological legacy of the the apparently innocent kinship metaphors of “mother tongue” and “native speaker” by historicizing their linguistic development. It shows how the early nation states constructed the ideology of ethnolinguistic nationalism, a composite of national language, identity, geography, and race. This ideology invented myths of congenital communities that configured the national language in a symbiotic matrix between body and physical environment and as the ethnic and corporeal ownership of national identity and local organic nature. These ethno-nationalist gestures informed the philology of the early modern era and generated arboreal and genealogical models of language, …

Density Based Pruning For Identification Of Differentially Expressed Genes From Microarray Data, Jianjun Hu, J. Xu

Faculty Publications

Motivation

Identification of differentially expressed genes from microarray datasets is one of the most important analyses for microarray data mining. Popular algorithms such as statistical t-test rank genes based on a single statistics. The false positive rate of these methods can be improved by considering other features of differentially expressed genes.

Results

We proposed a pattern recognition strategy for identifying differentially expressed genes. Genes are mapped to a two dimension feature space composed of average difference of gene expression and average expression levels. A density based pruning algorithm (DB Pruning) is developed to screen out potential differentially expressed genes usually …