Digital Commons Network^™

The Vaccinia Virus Complement Control Protein Modulates Adaptive Immune Responses During Infection, N. M. Girgis, Brian Dehaven

Biology Faculty Scholarship

Complement activation is an important component of the innate immune response against viral infection and also shapes adaptive immune responses. Despite compelling evidence that complement activation enhances T cell and antibody (Ab) responses during viral infection, it is unknown whether inhibition of complement by pathogens alters these responses. Vaccinia virus (VACV) modulates complement activation by encoding a complement regulatory protein called the vaccinia virus complement control protein (VCP). Although VCP has been described as a virulence factor, the mechanisms by which VCP enhances VACV pathogenesis have not been fully defined. Since complement is necessary for optimal adaptive immune responses to …

Summers With My Bapuji: Opening Up A World Of What-Ifs, Amit Patel

Neureuther Book Collection Essay Competition

Graduate Winner: 2nd Place, 2010. 23rd Annual Carl Neureuther Student Book Collection Competition

Vigorous Currents, Painful Archives: The Production Of Affect And History In Poe's "Tale Of The Ragged Mountains", Christina Zwarg

English Faculty Scholarship

First delivered as a paper at the Poe conference in Philadelphia in 2009, this extended version reveals how Poe's mesmeric tale can help us rethink trauma theory before Freud. Poe's strategic use of archival materials concerning an 18th-century insurrection in India provides compelling insight into the transmission of affect in the construction of global histories. --author-supplied description

Regulating Polygamy: Intimacy, Default Rules, And Bargaining For Equality, Adrienne D. Davis

Scholarship@WashULaw

Most legal scholarship about polygamy has approached it in one of two ways. Some have framed it as a question of how far constitutional protection for religious freedom and privacy rights extends, including what we might think of as “intimacy liberty,” particularly in light of Lawrence v. Texas. Others have debated decriminalization, based on the contested effects of polygamy on matters ranging from women’s subordination to fraudulent behavior to democracy. This Essay shifts attention from the constitutionality and decriminalization debates to a new set of questions: whether and how polygamy might be effectively recognized and regulated, consistent with contemporary social …

Making Up Is Hard To Do: Race/Gender/Sexual Orientation In The Law School Classroom, Adrienne D. Davis, Robert S. Chang

Scholarship@WashULaw

This exchange of letters picks up where Professors Adrienne Davis and Robert Chang left off in an earlier exchange that examined who speaks, who is allowed to speak, and what is remembered. Here, Professors Davis and Chang explore the dynamics of race, gender, and sexual orientation in the law school classroom. They compare the experiences of African American women and Asian American men in trying to perform as law professors, considering how makeup and other gender tools simultaneously assist and hinder such performances. Their exchange examines the possibility of bias that complicates the use of student evaluations in assessing teaching …

Introduction To The Symposium: The Politics Of Identity After Identity Politics, Adrienne D. Davis

Scholarship@WashULaw

The Essays in this volume seek to shed some light on the politics of identity after the 2008 Presidential election in which identity politics dominated. To explore how 2008 and its aftermath have shifted both academic and political debates, Professor Adrienne Davis invited scholars from a variety of disciplines who embrace diverse methodologies—political theory; cultural studies; history; and law. These authors explore identity politics as a field of academic inquiry; a cultural discourse; a legal claim; a negotiation of institutions and power; and a predicate for political alliances. Collectively, the Articles both develop new frameworks and intervene in old ones …

Three Snapshots Of Scholarly Engagement: Catharine Mackinnon’S Ethical Entrenchment, Transformative Politics, And Personal Commitment, Adrienne D. Davis

Scholarship@WashULaw

One of Catharine MacKinnon's germinal works calls attention to the political effects of modifiers. So, I was intrigued by the modifier of the conference panel that sparked this essay, the "engaged" scholar. I was struck by the quite distinct connotations invoked by this modifier. Of course there is the use I believe was envisioned by the plenary organizers as characterizing Professor MacKinnon's stunning body of legal work: engaged as in connected to something, seriously paying attention to consequences, rigorous and sustained involvement with a subject. Yet there are other connotations of engaged that I think are also helpful in understanding …

Heat Stress Evaluation Of Protective Clothing Ensembles, Amanda Lee Pease

USF Tampa Graduate Theses and Dissertations

Clothing directly affects the level of heat stress exposure. Useful measures to express the thermal characteristics are WBGT (wet bulb globe temperature) clothing adjustment factor (CAF) or apparent total evaporative resistance (R_e,T,_a). The CAF is assigned through laboratory wear trials following a heat stress protocol in which the air temperature and humidity are progressively increased until the participant clearly loses the ability to maintain thermal equilibrium. The critical condition is the point of thermal transition and from these conditions both the CAF and Re,T,a are computed. The first objective of this study is to compare the …

A Mixed-Methods Research Study Comparing Observations During Integrated Curriculum Lessons With Traditional Single-Subject Lessons For Primary-Age Students, Ksenia Sergeevna Zhbanova

Graduate Research Papers

This study examined teacher talk and actions under two conditions: ( 1) subject-integrated lessons of an integrated curriculum unit on African culture ( experimental condition); and (2) single subject-focused lessons of a traditional separate subject curriculum on mathematics time and money measurement (control condition). The study sought to define and compare characteristics of both curriculum approaches. Although the study was primarily qualitative with observations being recorded by the researcher that were subsequently sorted into categories through a constant comparison method, counts of frequency of observations in categories were recorded, resulting in a mixed-methods design.

The observations were collected in two …

Fifth Grade Student Learning And Interest In The American Revolution Through Reading Graphic Novels Compared To Reading Biography Or Other Nonfiction Books, Kari Bosma

Graduate Research Papers

The purpose of this study was to examine student recall of facts, along with enjoyment of reading and interest in the topic when using graphic novels as compared to illustrated nonfiction prose in social studies content area reading. Twenty-two fifth grade students (13 f, 9 m) in a public school in a Midwestern state participated in the study. Half of the students read about the Boston Massacre and Patrick Henry through graphic novels and read about Paul Revere and the Boston Tea Party with illustrated nonfiction texts, with the other half doing the opposite. The mean number of correct ideas …

Caffeine, Exercise And The Human Body: Men Vs. Women, Allison Marie Miller

Graduate Research Papers

No abstract provided.

North Dakota's Pharmacy Ownership Law: An Analysis Of The Strictest Pharmacy Ownership Law In The United States, Stefanie Haarsager

North Dakota Law Review

No abstract provided.

Bankruptcy—Exemptions: When An Interested Party Must Object, And Exempting Property With The Intention Of Retaining Possession, Jonathan L. Voigt

North Dakota Law Review

Schwab v. Reilly, 130 S. Ct. 2652 (2010)In Schwab v. Reilly, the United States Supreme Court partially frustrated the primary purpose of bankruptcy by making it more difficult for the debtor to exempt property itself, rather than a liquidated interest in that property. The Supreme Court held that when a debtor lists the value of the property the debtor wishes to exempt as equal to the fair market value of the property as listed on the debtor’s schedules, the debtor has not effectively exempted the property itself, but rather only an interest in the property up to the value the …

Let's Go Sue: The Attorney General's Historical Perspective On State Of North Dakota V. National Collegiate Athletic Association, Wayne Stenehjem, Matthew Sagsveen

North Dakota Law Review

No abstract provided.

3d Visualization Of Hiv Virions By Cryoelectron Tomography, Jun Liu, Elizabeth R Wright, Hanspeter Winkler

Faculty, Staff and Student Publications

The structure of the human immunodeficiency virus (HIV) and some of its components have been difficult to study in three-dimensions (3D) primarily because of their intrinsic structural variability. Recent advances in cryoelectron tomography (cryo-ET) have provided a new approach for determining the 3D structures of the intact virus, the HIV capsid, and the envelope glycoproteins located on the viral surface. A number of cryo-ET procedures related to specimen preservation, data collection, and image processing are presented in this chapter. The techniques described herein are well suited for determining the ultrastructure of bacterial and viral pathogens and their associated molecular machines …

Subacute Neural Stem Cell Therapy For Traumatic Brain Injury, Mikhail Bogdanov, Philip N Heacock, William Dowhan

Faculty, Staff and Student Publications

A protocol is described using lipid mutants and thiol-specific chemical reagents to study lipid-dependent and host-specific membrane protein topogenesis by the substituted-cysteine accessibility method as applied to transmembrane domains (SCAM). SCAM is adapted to follow changes in membrane protein topology as a function of changes in membrane lipid composition. The strategy described can be adapted to any membrane system.

Demonstrations Of Pedagogical Content Knowledge: Spanish Liberal Arts And Spanish Education Majors' Writing, Anne Cummings Hlas, Susan A. Hildebrandt

Faculty Publications – Languages, Literatures, and Cultures

Second language teachers’ pedagogical content knowledge (PCK) is a sophisticated combination of pedagogical and content knowledge. This study explores the acquisition and articulation of PCK, highlighting the question of whether teacher education programs add to language teachers' knowledge base. Data was gathered using a performance assessment that incorporated teacher writing tasks in Spanish with a reflective paragraph to explain decisions made while writing. Areas of interest were language awareness, knowledge of effective teaching, and knowledge of learners. The study’s primary purpose is to reveal whether PCK differed in preservice Spanish teachers’ writing, as compared to Spanish Liberal Arts majors’ writing. …

More Than Synaptic Plasticity: Role Of Nonsynaptic Plasticity In Learning And Memory, Riccardo Mozzachiodi, John H Byrne

Faculty, Staff and Student Publications

Decades of research on the cellular mechanisms of memory have led to the widely held view that memories are stored as modifications of synaptic strength. These changes involve presynaptic processes, such as direct modulation of the release machinery, or postsynaptic processes, such as modulation of receptor properties. Parallel studies have revealed that memories might also be stored by nonsynaptic processes, such as modulation of voltage-dependent membrane conductances, which are expressed as changes in neuronal excitability. Although in some cases nonsynaptic changes can function as part of the engram itself, they might also serve as mechanisms through which a neural circuit …

A Fall From Grace: United States V. W.R. Grace And The Need For Criminal Discovery Reform, Andrew King-Ries, Beth Brennan

Faculty Law Review Articles

This article examines several 2009 cases involving prosecutorial misconduct arising from the federal government's failure to live up to its criminal discovery obligations. The article focuses specifically on U.S. v. W.R. Grace, a Clean Air Act criminal case in Montana. The authors' analysis of Grace and other cases suggests that the absence of a clear, enforceable rule jeopardizes the government's ability to fairly prosecute its cases and supports amending Rule 16 to eliminate the gap between prosecutors' legal and ethical duties, and to require the pretrial disclosure of evidence favorable to the defendant.

The Campus Crime And Security Report, V. 14 (Fall 2009), Illinois State University Police Department

Clery Act Annual Security Report

Illinois State University Police Department Annual Security Report

A Bittersweet Heritage: Learning From The Making Of South African Legal Culture, Stephen Ellmann

Articles & Chapters

This essay responds to Martin Chanock's argument that race tainted the entire enterprise of South African judging. It seeks to understand how that could have been so, and looks to such driving forces as whites' guilt, denial, identity-building, self-protection, and legitimation for explanations. Then it asks whether an institution so tainted should now be altogether abandoned as part of the rebuilding of post-apartheid South Africa. The essay answers that much should be changed, but that the existence of a judiciary laying claim to a special expertise and responsibility in interpreting law and protecting rights a key heritage of the old …

Student Affairs Viewbook, 2010-2011, Division Of Student Affairs, Illinois State University

Student Affairs Viewbook

No abstract provided.

Social Support In An Internet Weight Loss Community, Kevin O Hwang, Allison J Ottenbacher, Angela P Green, M Roseann Cannon-Diehl, Oneka Richardson, Elmer V Bernstam, Eric J Thomas

Faculty, Staff and Student Publications

Purpose: To describe social support for weight loss shared by members of a large Internet weight loss community.

Methods: We conducted a mixed-methods study with surveys (n=193) and interviews (n=13) of community members along with a content analysis of discussion forum messages (n=1924 messages). Qualitative data were analyzed for social support themes.

Results: Survey respondents were primarily white (91.4%) and female (93.8%) with mean age 37.3 years and mean body mass index 30.9. They used forums frequently, with 56.8% reading messages, 36.1% replying to messages, and 18.5% posting messages to start a discussion related to weight loss on a daily …

Determinants Of Self-Employment In The United States, Viktoriya Nikolova, Michael S. Bargar

Undergraduate Economic Review

The prominence entrepreneurs have occupied in the popular imagination belies their relative neglect in formal economic theory. This paper adds to the growing body of work on entrepreneurs by examining the characteristics of self-employed individuals in the National Longitudinal Survey of Youth 1997. We believe our article to be the first that uses this fresh body of data for this purpose. Employing the standard binomial probit model with a list of potentially significant variables drawn from existing literature, we discovered that women are significantly less likely to be self-employed than men.

Can Sweden Afford Another High Equity Premium?, Matthew K. Miller

Undergraduate Economic Review

This paper calculates the empirical equity premium in Sweden between 1919-2006 and disaster probabilities of 25% and 50% contractions in real Gross Domestic Product. The calculation puts the equity premium at approximately 8%, 2% higher than what appears in the historical United States data, due to rare disaster events outside and idiosyncratic to Sweden. This study makes two important contributions. First, it projects that Sweden can afford the economic cost of another high equity premium but should remain cautious. Second, this paper affirms that WWII increased investors' perceptions of future equity risk despite Sweden's neutrality. To arrive at the empirical …

Economic Transformation And Urban-Rural Disparity In China, 2002-2008, Lingyi Sun

Undergraduate Economic Review

The year 2008 marked the 30th anniversary of China's beginning on its path of economic transformation. During the past three decades, a series of reform policies have been carried out to liberalize the economy and attract foreign investments. Rapid economic growth is accompanied by rising inequality. The Gini Coefficient of China increased from 0.23 in 1980 to 0.47 in 2005, according to official statistics (NBS). This disequalizing trend coincides with the initial stage of the debated Kuznets curve in which inequality of income distribution first increases during urbanization because of the difference between returns to industries and agriculture; then decreases …

Greg Shaw, Charlie Schlenker

Interviews for WGLT

Charlie Schlenker of WGLT interviews Professor of Political Science Greg Shaw about his book, The Healthcare Debate. (requires RealPlayer)

Broadening Ethics Teaching In Engineering: Beyond The Individualistic Approach, Eddie Conlon, H. Zandvoort

Articles

There is a widespread approach to the teaching of ethics to engineering students in which the exclusive focus is on engineers as individual agents and the broader context in which they do their work is ignored. Although this approach has frequently been criticised in the literature, it persists on a wide scale, as can be inferred from accounts in the educational literature and from the contents of widely used textbooks in engineering ethics. In this contribution we intend to: (1) Restate why the individualistic approach to the teaching of ethics to engineering students is inadequate in view of preparing them …

Reconceptualizing Vagrancy And Reconstructing The Vagrant: A Socio-Legal Analysis Of Criminal Law Reform In Canada, 1953-1972, Prashan Ranasinhe

Osgoode Hall Law Journal

This article explores significant reforms to the vagrancy section of the Criminal Code during the mid-to-late twentieth century. By locating the reforms within their unique social, political, and economic climates, I examine how they reconceptualized the offence of vagrancy and concomitantly reconstructed the vagrant as a social problem. The reforms played a seminal role in reducing the number of vagrancy offences, eventually leading to the demise of vagrancy in the criminal law. Yet, while the "vagrant" ceased to exist in the law, the law still continues to preserve vestiges of the vagrant in a highly gendered manner.

Reconciling The Science And Economics Of Climate Change, Eban Goodstein

Clemens Lecture Series

No abstract provided.